ZA200103630B - Particles coated with granulated crystalline ibuprofen. - Google Patents

Particles coated with granulated crystalline ibuprofen. Download PDF

Info

Publication number
ZA200103630B
ZA200103630B ZA200103630A ZA200103630A ZA200103630B ZA 200103630 B ZA200103630 B ZA 200103630B ZA 200103630 A ZA200103630 A ZA 200103630A ZA 200103630 A ZA200103630 A ZA 200103630A ZA 200103630 B ZA200103630 B ZA 200103630B
Authority
ZA
South Africa
Prior art keywords
ibuprofen
particles
weight
ethyl cellulose
coating
Prior art date
Application number
ZA200103630A
Other languages
English (en)
Inventor
Jean-Marc Zuccarelli
Charles Andre Chauveau
Gilles Demichelis
Karine Jean
Original Assignee
Prod Ethiques Ethypharm Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prod Ethiques Ethypharm Sa Lab filed Critical Prod Ethiques Ethypharm Sa Lab
Publication of ZA200103630B publication Critical patent/ZA200103630B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/501Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Glanulating (AREA)
ZA200103630A 1998-11-06 2001-05-04 Particles coated with granulated crystalline ibuprofen. ZA200103630B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9814033A FR2785539B1 (fr) 1998-11-06 1998-11-06 Particules enrobees d'ibuprofene cristallin granule

Publications (1)

Publication Number Publication Date
ZA200103630B true ZA200103630B (en) 2002-05-06

Family

ID=9532492

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200103630A ZA200103630B (en) 1998-11-06 2001-05-04 Particles coated with granulated crystalline ibuprofen.

Country Status (26)

Country Link
US (1) US6951657B1 (de)
EP (1) EP1126829B1 (de)
JP (1) JP3987282B2 (de)
KR (1) KR100586059B1 (de)
CN (1) CN1154482C (de)
AT (1) ATE265206T1 (de)
AU (1) AU765765B2 (de)
BR (1) BR9915111A (de)
CA (1) CA2349503C (de)
CZ (1) CZ292290B6 (de)
DE (1) DE69916876T2 (de)
DK (1) DK1126829T3 (de)
EA (1) EA002897B1 (de)
ES (1) ES2219073T3 (de)
FR (1) FR2785539B1 (de)
HK (1) HK1039890B (de)
HU (1) HU229936B1 (de)
IL (1) IL142787A (de)
MX (1) MXPA01004517A (de)
NZ (1) NZ511479A (de)
PL (1) PL194527B1 (de)
PT (1) PT1126829E (de)
SK (1) SK283944B6 (de)
TR (1) TR200101230T2 (de)
WO (1) WO2000027368A1 (de)
ZA (1) ZA200103630B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2795962B1 (fr) 1999-07-08 2003-05-09 Prographarm Laboratoires Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif
FR2824477B1 (fr) * 2001-05-09 2005-09-09 Ethypharm Lab Prod Ethiques Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes
FR2850275B1 (fr) * 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
EP1800667A1 (de) 2005-12-23 2007-06-27 Losan Pharma GmbH Schnell lösliches Ibuprofen-Granulat
AU2006226293B2 (en) * 2005-03-22 2011-04-07 Losan Pharma Gmbh Solubilized ibuprofen
US8067451B2 (en) * 2006-07-18 2011-11-29 Horizon Pharma Usa, Inc. Methods and medicaments for administration of ibuprofen
EP1919288A4 (de) * 2005-07-18 2009-12-16 Horizon Therapeutics Inc Famotidin- und ibuprofenhaltige arzneimittel und ihre verabreichung
US20080020040A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Unit dose form for administration of ibuprofen
DE102005049001A1 (de) * 2005-10-11 2007-04-12 Basf Ag Verfahren zur Herstellung von direkttablettierbaren Ibuprofen-Formulierungen
US8067033B2 (en) 2007-11-30 2011-11-29 Horizon Pharma Usa, Inc. Stable compositions of famotidine and ibuprofen
ATE553755T1 (de) * 2006-07-27 2012-05-15 Univ Sunderland Stärke enthaltende beschichtungszusammensetzung
TWI564008B (zh) 2010-09-30 2017-01-01 鹽野義製藥股份有限公司 難溶性藥物之溶解性改善製劑
WO2014198999A1 (en) * 2013-06-13 2014-12-18 Opes Corporation Oy Matrix
US9474699B2 (en) * 2014-03-31 2016-10-25 Johnson & Johnson Consumer Inc. Compostions and methods for enhancing the topical application of a basic benefit agent
WO2016081783A1 (en) * 2014-11-19 2016-05-26 Kiromic, Llc Novel nanoparticle-based vaccine targeting cancer/testis antigens (cta) and its use in solid and hematological malignancies
WO2019080693A1 (zh) 2017-10-26 2019-05-02 浙江越甲药业有限公司 一种稳定的含有非甾体抗炎药衍生物的药物组合物
AU2020225818A1 (en) 2019-02-22 2021-10-14 Catalent U.K. Swindon Zydis Limited Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension
GB2597577B (en) 2019-02-22 2023-09-20 Catalent Uk Swindon Zydis Ltd Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen
CN113453662A (zh) * 2019-02-22 2021-09-28 康特伦英国斯温顿捷迪斯有限公司 储存期间药物颗粒包衣材料的团聚最小化以稳定化药物产品的崩解时间

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4308251A (en) * 1980-01-11 1981-12-29 Boots Pharmaceuticals, Inc. Controlled release formulations of orally-active medicaments
US4588612A (en) * 1985-04-24 1986-05-13 Scm Corporation Pretreatment in encapsulation process
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
US4835186A (en) 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
NZ234587A (en) * 1989-08-04 1991-11-26 Mcneil Ppc Inc A chewable pharmaceutical tablet of compressed coated granules
IT1241417B (it) * 1990-03-06 1994-01-14 Vectorpharma Int Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
CA2076983A1 (en) * 1990-04-11 1991-10-12 Robert Wu-Wei Shen Taste masking of ibuprofen by fluid bed coating
FR2679451B1 (fr) * 1991-07-22 1994-09-09 Prographarm Laboratoires Comprime multiparticulaire a delitement rapide.
US5191114A (en) * 1991-10-09 1993-03-02 Sage Pharmaceuticals, Inc. Process for enhancing the flow characteristics of ibuprofen
ZA945944B (en) * 1993-08-13 1996-02-08 Eurand America Inc Procedure for encapsulating nsaids
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)

Also Published As

Publication number Publication date
NZ511479A (en) 2003-02-28
ATE265206T1 (de) 2004-05-15
EP1126829B1 (de) 2004-04-28
AU1050800A (en) 2000-05-29
EA200100491A1 (ru) 2001-12-24
FR2785539B1 (fr) 2004-04-09
KR20010090830A (ko) 2001-10-19
CZ292290B6 (cs) 2003-08-13
CN1328450A (zh) 2001-12-26
CA2349503A1 (fr) 2000-05-18
US6951657B1 (en) 2005-10-04
HK1039890B (zh) 2005-01-07
MXPA01004517A (es) 2003-06-09
PL347549A1 (en) 2002-04-08
SK5662001A3 (en) 2001-11-06
JP3987282B2 (ja) 2007-10-03
KR100586059B1 (ko) 2006-06-07
AU765765B2 (en) 2003-09-25
BR9915111A (pt) 2001-11-27
PL194527B1 (pl) 2007-06-29
HU229936B1 (en) 2015-01-28
JP2002529399A (ja) 2002-09-10
EP1126829A1 (de) 2001-08-29
DK1126829T3 (da) 2004-08-09
HK1039890A1 (en) 2002-05-17
FR2785539A1 (fr) 2000-05-12
HUP0104394A3 (en) 2002-12-28
DE69916876D1 (de) 2004-06-03
TR200101230T2 (tr) 2001-10-22
ES2219073T3 (es) 2004-11-16
WO2000027368A1 (fr) 2000-05-18
DE69916876T2 (de) 2005-03-31
PT1126829E (pt) 2004-08-31
CN1154482C (zh) 2004-06-23
HUP0104394A2 (hu) 2002-03-28
SK283944B6 (sk) 2004-05-04
IL142787A (en) 2007-06-03
EA002897B1 (ru) 2002-10-31
CA2349503C (fr) 2010-07-13
CZ20011434A3 (cs) 2001-09-12

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