SK282925B6 - Substituované benzylaminopiperidíny, ich použitie a farmaceutické prostriedky na ich báze - Google Patents

Substituované benzylaminopiperidíny, ich použitie a farmaceutické prostriedky na ich báze Download PDF

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Publication number
SK282925B6
SK282925B6 SK207-98A SK20798A SK282925B6 SK 282925 B6 SK282925 B6 SK 282925B6 SK 20798 A SK20798 A SK 20798A SK 282925 B6 SK282925 B6 SK 282925B6
Authority
SK
Slovakia
Prior art keywords
compound
trifluoromethyl
phenylpiperidine
methoxy
amino
Prior art date
Application number
SK207-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK20798A3 (en
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of SK20798A3 publication Critical patent/SK20798A3/sk
Publication of SK282925B6 publication Critical patent/SK282925B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SK207-98A 1995-08-24 1996-06-10 Substituované benzylaminopiperidíny, ich použitie a farmaceutické prostriedky na ich báze SK282925B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24
PCT/IB1996/000572 WO1997008144A1 (en) 1995-08-24 1996-06-10 Substituted benzylaminopiperidine compounds

Publications (2)

Publication Number Publication Date
SK20798A3 SK20798A3 (en) 1999-03-12
SK282925B6 true SK282925B6 (sk) 2003-01-09

Family

ID=11004362

Family Applications (1)

Application Number Title Priority Date Filing Date
SK207-98A SK282925B6 (sk) 1995-08-24 1996-06-10 Substituované benzylaminopiperidíny, ich použitie a farmaceutické prostriedky na ich báze

Country Status (41)

Country Link
US (1) US6506775B1 (cs)
EP (2) EP1114817B1 (cs)
JP (1) JP3084069B2 (cs)
KR (1) KR100288673B1 (cs)
CN (1) CN1153764C (cs)
AP (1) AP643A (cs)
AR (1) AR006305A1 (cs)
AT (2) ATE258166T1 (cs)
AU (1) AU702698B2 (cs)
BG (1) BG64126B1 (cs)
BR (1) BR9609989A (cs)
CA (1) CA2227814C (cs)
CO (1) CO4480738A1 (cs)
CZ (1) CZ297543B6 (cs)
DE (2) DE69631390T2 (cs)
DK (2) DK1114817T3 (cs)
DZ (1) DZ2086A1 (cs)
ES (2) ES2211684T3 (cs)
HR (1) HRP960386B1 (cs)
HU (1) HU225480B1 (cs)
IL (1) IL119078A (cs)
IS (1) IS1947B (cs)
MA (1) MA23961A1 (cs)
MX (1) MX9801467A (cs)
MY (1) MY114800A (cs)
NO (1) NO310720B1 (cs)
NZ (1) NZ308207A (cs)
OA (1) OA10666A (cs)
PE (2) PE20010700A1 (cs)
PL (1) PL186773B1 (cs)
PT (2) PT1114817E (cs)
RO (1) RO119299B1 (cs)
RU (1) RU2152930C2 (cs)
SI (2) SI1114817T1 (cs)
SK (1) SK282925B6 (cs)
TN (1) TNSN96107A1 (cs)
TR (1) TR199800300T1 (cs)
TW (1) TW340842B (cs)
UA (1) UA48981C2 (cs)
WO (1) WO1997008144A1 (cs)
YU (1) YU49122B (cs)

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JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
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CA2415532C (en) 2000-07-11 2010-05-11 Albany Molecular Research, Inc. Novel 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof
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US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
MXPA05011223A (es) 2003-04-18 2006-01-26 Lilly Co Eli Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif.
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US8362075B2 (en) 2005-05-17 2013-01-29 Merck Sharp & Dohme Corp. Cyclohexyl sulphones for treatment of cancer
CN101495184A (zh) 2005-07-15 2009-07-29 Amr科技公司 芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
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SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
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US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
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JP5319518B2 (ja) 2007-04-02 2013-10-16 Msd株式会社 インドールジオン誘導体
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JP5511080B2 (ja) 2008-03-31 2014-06-04 興和株式会社 1,3−ジヒドロイソベンゾフラン誘導体
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US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
BR9205807A (pt) * 1991-03-26 1994-06-28 Pfizer Preparação estéreo-seletiva de piperidinas substituidas
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US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
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Also Published As

Publication number Publication date
PT1114817E (pt) 2004-05-31
IL119078A0 (en) 1996-11-14
DK1114817T3 (da) 2004-04-26
PE1398A1 (es) 1998-02-27
BG102288A (en) 1998-09-30
ES2211684T3 (es) 2004-07-16
US6506775B1 (en) 2003-01-14
DZ2086A1 (fr) 2002-07-22
ATE258166T1 (de) 2004-02-15
WO1997008144A1 (en) 1997-03-06
DE69631390T2 (de) 2004-11-25
PE20010700A1 (es) 2001-07-09
EP0861235A1 (en) 1998-09-02
CN1153764C (zh) 2004-06-16
PL186773B1 (pl) 2004-02-27
BG64126B1 (bg) 2004-01-30
BR9609989A (pt) 1999-07-06
AU702698B2 (en) 1999-03-04
SI1114817T1 (en) 2004-06-30
AU5776996A (en) 1997-03-19
HUP9901159A2 (hu) 1999-07-28
AP9600850A0 (en) 1996-10-31
NO310720B1 (no) 2001-08-20
DK0861235T3 (da) 2001-12-27
HUP9901159A3 (en) 2000-05-29
HK1014935A1 (en) 1999-10-08
DE69631390D1 (de) 2004-02-26
PL325332A1 (en) 1998-07-20
TNSN96107A1 (fr) 2005-03-15
ATE208377T1 (de) 2001-11-15
NO980751L (no) 1998-02-23
UA48981C2 (uk) 2002-09-16
MA23961A1 (fr) 1997-04-01
NZ308207A (en) 1998-07-28
AP643A (en) 1998-04-24
CA2227814C (en) 2002-12-31
CA2227814A1 (en) 1997-03-06
PT861235E (pt) 2002-03-28
SI0861235T1 (en) 2002-04-30
IS4644A (is) 1997-12-30
TW340842B (en) 1998-09-21
OA10666A (en) 2002-11-25
MY114800A (en) 2003-01-31
CZ297543B6 (cs) 2007-02-07
KR100288673B1 (ko) 2001-05-02
HU225480B1 (en) 2006-12-28
AR006305A1 (es) 1999-08-25
IL119078A (en) 2003-11-23
RU2152930C2 (ru) 2000-07-20
SK20798A3 (en) 1999-03-12
CO4480738A1 (es) 1997-07-09
DE69616817T2 (de) 2002-04-04
YU47896A (sh) 1998-12-23
JPH10510554A (ja) 1998-10-13
CN1193961A (zh) 1998-09-23
EP0861235B1 (en) 2001-11-07
HRP960386A2 (en) 1998-04-30
MX9801467A (es) 1998-05-31
JP3084069B2 (ja) 2000-09-04
HRP960386B1 (en) 2002-04-30
KR19990044077A (ko) 1999-06-25
RO119299B1 (ro) 2004-07-30
CZ52198A3 (cs) 1999-01-13
TR199800300T1 (xx) 1998-06-22
ES2163017T3 (es) 2002-01-16
EP1114817A1 (en) 2001-07-11
DE69616817D1 (de) 2001-12-13
EP1114817B1 (en) 2004-01-21
IS1947B (is) 2004-10-13
YU49122B (sh) 2004-03-12
NO980751D0 (no) 1998-02-23

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MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20090610