SK281568B6 - Spôsob hydrogenácie imínov - Google Patents

Spôsob hydrogenácie imínov Download PDF

Info

Publication number
SK281568B6
SK281568B6 SK1681-97A SK168197A SK281568B6 SK 281568 B6 SK281568 B6 SK 281568B6 SK 168197 A SK168197 A SK 168197A SK 281568 B6 SK281568 B6 SK 281568B6
Authority
SK
Slovakia
Prior art keywords
group
alkyl
carbon atoms
phenyl
benzyl
Prior art date
Application number
SK1681-97A
Other languages
English (en)
Slovak (sk)
Other versions
SK168197A3 (en
Inventor
Hans-Peter Jalett
Felix Spindler
Reinhard Georg Hanreich
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SK168197A3 publication Critical patent/SK168197A3/sk
Publication of SK281568B6 publication Critical patent/SK281568B6/sk

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
SK1681-97A 1995-06-08 1996-06-04 Spôsob hydrogenácie imínov SK281568B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH168595 1995-06-08
PCT/EP1996/002419 WO1996041793A1 (fr) 1995-06-08 1996-06-04 Procede d'hydrogenation des imines

Publications (2)

Publication Number Publication Date
SK168197A3 SK168197A3 (en) 1998-05-06
SK281568B6 true SK281568B6 (sk) 2001-05-10

Family

ID=4216210

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1681-97A SK281568B6 (sk) 1995-06-08 1996-06-04 Spôsob hydrogenácie imínov

Country Status (26)

Country Link
US (1) US5886225A (fr)
EP (1) EP0830337B1 (fr)
JP (1) JP4128623B2 (fr)
KR (1) KR100470884B1 (fr)
CN (1) CN1176900C (fr)
AR (1) AR002359A1 (fr)
AT (1) ATE187957T1 (fr)
AU (1) AU710870B2 (fr)
BR (1) BR9609159A (fr)
CA (1) CA2220999C (fr)
CZ (1) CZ287315B6 (fr)
DE (1) DE69605794T2 (fr)
DK (1) DK0830337T3 (fr)
EA (1) EA000498B1 (fr)
ES (1) ES2141512T3 (fr)
GR (1) GR3032521T3 (fr)
HR (1) HRP960253B1 (fr)
HU (1) HU229337B1 (fr)
IL (1) IL122184A (fr)
PL (1) PL183317B1 (fr)
PT (1) PT830337E (fr)
SK (1) SK281568B6 (fr)
TW (1) TW346482B (fr)
UA (1) UA51652C2 (fr)
WO (1) WO1996041793A1 (fr)
ZA (1) ZA964832B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100355255B1 (ko) * 1994-02-02 2002-12-31 노바티스 아게 이민의수소화방법
US6228971B1 (en) * 1999-06-21 2001-05-08 Ppg Industries Ohio, Inc. Polymeric imine functional compositions and their use in film-forming compositions
US20070213540A1 (en) * 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines
MX2010009162A (es) 2008-02-22 2010-12-21 Radius Health Inc Moduladores selectivos del receptor de androgeno.
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
EP2531029B1 (fr) 2010-02-04 2016-10-19 Radius Health, Inc. Modulateurs sélectifs du récepteur des androgènes
ME02474B (fr) 2010-05-12 2017-02-20 Radius Health Inc Schémas thérapeutiques
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
BR112013007685B1 (pt) 2010-09-28 2021-11-09 Radius Pharmaceuticals, Inc Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto
CN102153589B (zh) 2011-02-28 2013-01-02 大连多相触媒有限公司 一种亚胺的不对称加氢催化剂及其合成方法和应用
WO2014037962A1 (fr) 2012-09-06 2014-03-13 Council Of Scientific And Industrial Research Procédé de préparation de (s)-2-éthyl-n-(1-méthoxypropan-2-yl)-6-méthylaniline
EP4035664A3 (fr) 2014-03-28 2022-11-30 Duke University Traitement du cancer faisant intervenir des modulateurs sélectifs des récepteurs des strogènes
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
RU2769527C2 (ru) 2016-06-22 2022-04-01 Эллипсес Фарма Лтд Способы лечения ar+ рака молочной железы
KR102322802B1 (ko) 2017-01-05 2021-11-04 래디어스 파마슈티컬스, 인코포레이티드 Rad1901-2hcl의 다형 형태
US11643385B2 (en) 2018-07-04 2023-05-09 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCl
CN110305025B (zh) * 2019-07-23 2022-05-06 衢州学院 一种由亚胺催化氢化合成苄胺类化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4994615A (en) * 1986-08-04 1991-02-19 Ciba-Geigy Corporation Process for the preparation of optically active secondary arylamines
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
DE59009835D1 (de) * 1989-09-18 1995-12-07 Ciba Geigy Ag Iridiumkomplexe, Verfahren zu deren Herstellung und deren Verwendung.
SG42936A1 (en) * 1992-04-02 1997-10-17 Ciba Geigy Ag Ferrocenyl diphosphines as ligands for homogeneous catalysts
JPH09508400A (ja) * 1994-02-02 1997-08-26 チバ−ガイギー アクチエンゲゼルシャフト 水素化触媒、その調製方法および水素化方法

Also Published As

Publication number Publication date
US5886225A (en) 1999-03-23
CZ287315B6 (en) 2000-10-11
KR100470884B1 (ko) 2005-06-22
WO1996041793A1 (fr) 1996-12-27
CN1176900C (zh) 2004-11-24
DE69605794D1 (de) 2000-01-27
TW346482B (en) 1998-12-01
CA2220999C (fr) 2008-01-29
CZ391997A3 (cs) 1998-03-18
IL122184A0 (en) 1998-04-05
AR002359A1 (es) 1998-03-11
CA2220999A1 (fr) 1996-12-27
AU710870B2 (en) 1999-09-30
JPH11507917A (ja) 1999-07-13
EA000498B1 (ru) 1999-08-26
EP0830337A1 (fr) 1998-03-25
HRP960253B1 (en) 2000-10-31
ES2141512T3 (es) 2000-03-16
HUP9802307A2 (hu) 1999-02-01
EP0830337B1 (fr) 1999-12-22
GR3032521T3 (en) 2000-05-31
CN1187183A (zh) 1998-07-08
BR9609159A (pt) 1999-05-04
PT830337E (pt) 2000-05-31
UA51652C2 (uk) 2002-12-16
SK168197A3 (en) 1998-05-06
EA199700424A1 (ru) 1999-02-25
PL323946A1 (en) 1998-04-27
DK0830337T3 (da) 2000-06-13
PL183317B1 (pl) 2002-06-28
HU229337B1 (en) 2013-11-28
IL122184A (en) 2000-02-29
KR19990021908A (ko) 1999-03-25
HUP9802307A3 (en) 1999-03-29
ZA964832B (en) 1996-12-09
DE69605794T2 (de) 2000-07-20
JP4128623B2 (ja) 2008-07-30
AU6221896A (en) 1997-01-09
HRP960253A2 (en) 1997-10-31
ATE187957T1 (de) 2000-01-15

Similar Documents

Publication Publication Date Title
AU677753B2 (en) Process for the hydrogenation of imines
SK281568B6 (sk) Spôsob hydrogenácie imínov
US20070213540A1 (en) Process for the hydrogenation of imines
US6218559B1 (en) Hydrogenation catalyst, process for the preparation thereof and hydrogenation process
EP0848697B1 (fr) Procede d'hydrogenation d'imines
JP4094663B2 (ja) イミンの水素添加方法
CA2157191C (fr) Procede d'hydrogenation d'imines
MXPA96003137A (en) Catalyst of hydrogenation, procedure for its preparation, and procedure of hidrogenac

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20160604