DE69605794T2 - Verfahren zur hydrierung von iminen - Google Patents

Verfahren zur hydrierung von iminen

Info

Publication number
DE69605794T2
DE69605794T2 DE69605794T DE69605794T DE69605794T2 DE 69605794 T2 DE69605794 T2 DE 69605794T2 DE 69605794 T DE69605794 T DE 69605794T DE 69605794 T DE69605794 T DE 69605794T DE 69605794 T2 DE69605794 T2 DE 69605794T2
Authority
DE
Germany
Prior art keywords
hydrating
imines
hydrating imines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69605794T
Other languages
English (en)
Other versions
DE69605794D1 (de
Inventor
Hans-Peter Jalett
Felix Spindler
Reinhard Hanreich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of DE69605794D1 publication Critical patent/DE69605794D1/de
Publication of DE69605794T2 publication Critical patent/DE69605794T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
DE69605794T 1995-06-08 1996-06-04 Verfahren zur hydrierung von iminen Expired - Lifetime DE69605794T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH168595 1995-06-08
PCT/EP1996/002419 WO1996041793A1 (en) 1995-06-08 1996-06-04 Process for the hydrogenation of imines

Publications (2)

Publication Number Publication Date
DE69605794D1 DE69605794D1 (de) 2000-01-27
DE69605794T2 true DE69605794T2 (de) 2000-07-20

Family

ID=4216210

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69605794T Expired - Lifetime DE69605794T2 (de) 1995-06-08 1996-06-04 Verfahren zur hydrierung von iminen

Country Status (26)

Country Link
US (1) US5886225A (de)
EP (1) EP0830337B1 (de)
JP (1) JP4128623B2 (de)
KR (1) KR100470884B1 (de)
CN (1) CN1176900C (de)
AR (1) AR002359A1 (de)
AT (1) ATE187957T1 (de)
AU (1) AU710870B2 (de)
BR (1) BR9609159A (de)
CA (1) CA2220999C (de)
CZ (1) CZ287315B6 (de)
DE (1) DE69605794T2 (de)
DK (1) DK0830337T3 (de)
EA (1) EA000498B1 (de)
ES (1) ES2141512T3 (de)
GR (1) GR3032521T3 (de)
HR (1) HRP960253B1 (de)
HU (1) HU229337B1 (de)
IL (1) IL122184A (de)
PL (1) PL183317B1 (de)
PT (1) PT830337E (de)
SK (1) SK281568B6 (de)
TW (1) TW346482B (de)
UA (1) UA51652C2 (de)
WO (1) WO1996041793A1 (de)
ZA (1) ZA964832B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69505312T2 (de) * 1994-02-02 1999-04-08 Novartis Ag Verfahren zur hydrierung von iminen
US6228971B1 (en) * 1999-06-21 2001-05-08 Ppg Industries Ohio, Inc. Polymeric imine functional compositions and their use in film-forming compositions
US20070213540A1 (en) * 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines
ES2488990T3 (es) 2008-02-22 2014-09-01 Radius Health, Inc. Moduladores selectivos del receptor de andrógenos
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
EP2531029B1 (de) 2010-02-04 2016-10-19 Radius Health, Inc. Selektive androgenrezeptormodulatoren
WO2011143469A1 (en) 2010-05-12 2011-11-17 Radius Health,Inc Therapeutic regimens
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
WO2012047617A1 (en) 2010-09-28 2012-04-12 Radius Health, Inc. Selective androgen receptor modulators
CN102153589B (zh) 2011-02-28 2013-01-02 大连多相触媒有限公司 一种亚胺的不对称加氢催化剂及其合成方法和应用
US9199930B2 (en) 2012-09-06 2015-12-01 Council Of Scientific And Industrial Research Process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline
EP3834824A1 (de) 2014-03-28 2021-06-16 Duke University Verfahren zur behandlung von krebs unter verwendung von selektiven östrogenrezeptormodulatoren
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
WO2017223115A1 (en) 2016-06-22 2017-12-28 Radius Health, Inc. Ar+ breast cancer treatment methods
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ,インコーポレイテッド Rad1901-2hclの多形性形態
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
CN110305025B (zh) * 2019-07-23 2022-05-06 衢州学院 一种由亚胺催化氢化合成苄胺类化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE66666T1 (de) * 1986-08-04 1991-09-15 Ciba Geigy Ag Verfahren zur herstellung von optisch aktiven sekundaeren arylaminen.
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
US5112999A (en) * 1989-09-18 1992-05-12 Ciba-Geigy Corporation Iridium complexes, process for their preparation and their use
DE59309554D1 (de) * 1992-04-02 1999-06-10 Novartis Ag Ferrocenyldiphosphine als Liganden für homogene Katalysatoren
DK0741738T3 (da) * 1994-02-02 2000-04-17 Novartis Ag Hydrogeneringskatallysator, fremgangsmåde til fremstilling deraf og hydrogeneringsfremgangsmåde

Also Published As

Publication number Publication date
HUP9802307A2 (hu) 1999-02-01
WO1996041793A1 (en) 1996-12-27
IL122184A0 (en) 1998-04-05
PL323946A1 (en) 1998-04-27
HRP960253B1 (en) 2000-10-31
HU229337B1 (en) 2013-11-28
AR002359A1 (es) 1998-03-11
JPH11507917A (ja) 1999-07-13
PL183317B1 (pl) 2002-06-28
KR100470884B1 (ko) 2005-06-22
CN1187183A (zh) 1998-07-08
US5886225A (en) 1999-03-23
KR19990021908A (ko) 1999-03-25
HRP960253A2 (en) 1997-10-31
EP0830337A1 (de) 1998-03-25
DK0830337T3 (da) 2000-06-13
CZ287315B6 (en) 2000-10-11
CA2220999A1 (en) 1996-12-27
DE69605794D1 (de) 2000-01-27
PT830337E (pt) 2000-05-31
ES2141512T3 (es) 2000-03-16
CZ391997A3 (cs) 1998-03-18
UA51652C2 (uk) 2002-12-16
TW346482B (en) 1998-12-01
HUP9802307A3 (en) 1999-03-29
CA2220999C (en) 2008-01-29
AU6221896A (en) 1997-01-09
BR9609159A (pt) 1999-05-04
EA000498B1 (ru) 1999-08-26
GR3032521T3 (en) 2000-05-31
JP4128623B2 (ja) 2008-07-30
IL122184A (en) 2000-02-29
CN1176900C (zh) 2004-11-24
AU710870B2 (en) 1999-09-30
ZA964832B (en) 1996-12-09
ATE187957T1 (de) 2000-01-15
EP0830337B1 (de) 1999-12-22
SK281568B6 (sk) 2001-05-10
EA199700424A1 (ru) 1999-02-25
SK168197A3 (en) 1998-05-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SYNGENTA PARTICIPATIONS AG, BASEL, CH

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC