DK0830337T3 - Fremgangsmåde til hydrogenering af iminer - Google Patents

Fremgangsmåde til hydrogenering af iminer

Info

Publication number
DK0830337T3
DK0830337T3 DK96920786T DK96920786T DK0830337T3 DK 0830337 T3 DK0830337 T3 DK 0830337T3 DK 96920786 T DK96920786 T DK 96920786T DK 96920786 T DK96920786 T DK 96920786T DK 0830337 T3 DK0830337 T3 DK 0830337T3
Authority
DK
Denmark
Prior art keywords
imines
hydrogenation
Prior art date
Application number
DK96920786T
Other languages
Danish (da)
English (en)
Inventor
Hans-Peter Jalett
Felix Spindler
Reinhard Georg Hanreich
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK0830337T3 publication Critical patent/DK0830337T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/52Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of imines or imino-ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/88Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
DK96920786T 1995-06-08 1996-06-04 Fremgangsmåde til hydrogenering af iminer DK0830337T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH168595 1995-06-08
PCT/EP1996/002419 WO1996041793A1 (fr) 1995-06-08 1996-06-04 Procede d'hydrogenation des imines

Publications (1)

Publication Number Publication Date
DK0830337T3 true DK0830337T3 (da) 2000-06-13

Family

ID=4216210

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96920786T DK0830337T3 (da) 1995-06-08 1996-06-04 Fremgangsmåde til hydrogenering af iminer

Country Status (26)

Country Link
US (1) US5886225A (fr)
EP (1) EP0830337B1 (fr)
JP (1) JP4128623B2 (fr)
KR (1) KR100470884B1 (fr)
CN (1) CN1176900C (fr)
AR (1) AR002359A1 (fr)
AT (1) ATE187957T1 (fr)
AU (1) AU710870B2 (fr)
BR (1) BR9609159A (fr)
CA (1) CA2220999C (fr)
CZ (1) CZ287315B6 (fr)
DE (1) DE69605794T2 (fr)
DK (1) DK0830337T3 (fr)
EA (1) EA000498B1 (fr)
ES (1) ES2141512T3 (fr)
GR (1) GR3032521T3 (fr)
HR (1) HRP960253B1 (fr)
HU (1) HU229337B1 (fr)
IL (1) IL122184A (fr)
PL (1) PL183317B1 (fr)
PT (1) PT830337E (fr)
SK (1) SK281568B6 (fr)
TW (1) TW346482B (fr)
UA (1) UA51652C2 (fr)
WO (1) WO1996041793A1 (fr)
ZA (1) ZA964832B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691949B1 (fr) * 1994-02-02 1998-10-14 Novartis AG Procede d'hydrogenation d'imines
US6228971B1 (en) * 1999-06-21 2001-05-08 Ppg Industries Ohio, Inc. Polymeric imine functional compositions and their use in film-forming compositions
US20070213540A1 (en) * 2006-03-09 2007-09-13 Degussa Ag Process for the hydrogenation of imines
BRPI0907844B8 (pt) 2008-02-22 2021-05-25 Radius Health Inc compostos e método para modular um receptor de andrógeno, processos de preparação e composição farmacêutica dos mesmos e seus usos
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
JP5964756B2 (ja) 2010-02-04 2016-08-03 ラジウス ヘルス,インコーポレイテッド 選択的アンドロゲン受容体モジュレーター
PL2568806T3 (pl) 2010-05-12 2017-03-31 Radius Health, Inc. Schematy lecznicze
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
WO2012047617A1 (fr) 2010-09-28 2012-04-12 Radius Health, Inc. Modulateurs sélectifs du récepteur des androgènes
CN102153589B (zh) 2011-02-28 2013-01-02 大连多相触媒有限公司 一种亚胺的不对称加氢催化剂及其合成方法和应用
US9199930B2 (en) 2012-09-06 2015-12-01 Council Of Scientific And Industrial Research Process for the preparation of (S)-2-ethyl-N-(1-methoxypropan-2-yl)-6-methyl aniline
FI3122426T3 (fi) 2014-03-28 2023-03-31 Univ Duke Rintasyövän hoitaminen käyttäen selektiivisiä estrogeenin reseptorin modulaattoreita
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
PL3474841T3 (pl) 2016-06-22 2022-07-11 Ellipses Pharma Ltd Sposoby leczenia nowotworu złośliwego piersi ar+
AU2018205285C9 (en) 2017-01-05 2024-05-23 Radius Pharmaceuticals, Inc. Polymorphic forms of RAD1901-2HCl
CA3104395A1 (fr) 2018-07-04 2020-01-09 Radius Pharmaceuticals, Inc. Formes polymorphes de rad1901-2hcl
CN110305025B (zh) * 2019-07-23 2022-05-06 衢州学院 一种由亚胺催化氢化合成苄胺类化合物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256982B1 (fr) * 1986-08-04 1991-08-28 Ciba-Geigy Ag Procédé pour la fabrication d'amines aryles secondaires optiquement actives
US5011995A (en) * 1987-07-28 1991-04-30 Ciba-Geigy Corporation Process for the preparation of optically active secondary amines
US5112999A (en) * 1989-09-18 1992-05-12 Ciba-Geigy Corporation Iridium complexes, process for their preparation and their use
EP0564406B1 (fr) * 1992-04-02 1999-05-06 Novartis AG Ferrocenyldiphosphine comme ligandes de catalyseurs homogènes
WO1995021176A1 (fr) * 1994-02-02 1995-08-10 Ciba-Geigy Ag Catalyseur d'hydrogenation, son procede de preparation et procede d'hydrogenation

Also Published As

Publication number Publication date
DE69605794T2 (de) 2000-07-20
CN1187183A (zh) 1998-07-08
US5886225A (en) 1999-03-23
JP4128623B2 (ja) 2008-07-30
JPH11507917A (ja) 1999-07-13
UA51652C2 (uk) 2002-12-16
EA000498B1 (ru) 1999-08-26
KR100470884B1 (ko) 2005-06-22
GR3032521T3 (en) 2000-05-31
EA199700424A1 (ru) 1999-02-25
CZ391997A3 (cs) 1998-03-18
BR9609159A (pt) 1999-05-04
HUP9802307A2 (hu) 1999-02-01
IL122184A (en) 2000-02-29
HRP960253A2 (en) 1997-10-31
AR002359A1 (es) 1998-03-11
IL122184A0 (en) 1998-04-05
TW346482B (en) 1998-12-01
SK168197A3 (en) 1998-05-06
CN1176900C (zh) 2004-11-24
SK281568B6 (sk) 2001-05-10
KR19990021908A (ko) 1999-03-25
DE69605794D1 (de) 2000-01-27
HRP960253B1 (en) 2000-10-31
PL323946A1 (en) 1998-04-27
AU6221896A (en) 1997-01-09
HU229337B1 (en) 2013-11-28
CZ287315B6 (en) 2000-10-11
PT830337E (pt) 2000-05-31
AU710870B2 (en) 1999-09-30
EP0830337B1 (fr) 1999-12-22
ZA964832B (en) 1996-12-09
CA2220999A1 (fr) 1996-12-27
HUP9802307A3 (en) 1999-03-29
EP0830337A1 (fr) 1998-03-25
CA2220999C (fr) 2008-01-29
PL183317B1 (pl) 2002-06-28
ES2141512T3 (es) 2000-03-16
WO1996041793A1 (fr) 1996-12-27
ATE187957T1 (de) 2000-01-15

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