US3361742A
(en)
|
1964-12-07 |
1968-01-02 |
Hoffmann La Roche |
5-oxo-1h-pyrrolo-[2, 1-c][1, 4]-benzodiazepin-2-crylamides
|
US3523941A
(en)
|
1967-03-06 |
1970-08-11 |
Hoffmann La Roche |
Benzodiazepine compounds and process for their preparation
|
US3524849A
(en)
|
1967-10-27 |
1970-08-18 |
Hoffmann La Roche |
Process for the preparation of pyrrolo-benzodiazepine acrylamides and intermediates useful therein
|
IL33558A
(en)
|
1968-12-30 |
1973-10-25 |
Fujisawa Pharmaceutical Co |
Antibiotic pyrrolo-benzodiazepine compound,its derivatives and processes for their production
|
JPS4843755B1
(sl)
|
1969-06-26 |
1973-12-20 |
|
|
DE1965304A1
(de)
|
1968-12-30 |
1970-07-23 |
Fujisawa Pharmaceutical Co |
Benzdiazepinon-Verbindungen und Verfahren zu ihrer Herstellung
|
JPS6053033B2
(ja)
|
1976-12-28 |
1985-11-22 |
財団法人微生物化学研究会 |
新制癌抗生物質マゼスラマイシン及びその製造方法
|
JPS585916B2
(ja)
|
1977-12-27 |
1983-02-02 |
株式会社ミドリ十字 |
新規ベンゾジアゼピン系化合物
|
JPS5615289A
(en)
|
1979-07-17 |
1981-02-14 |
Green Cross Corp:The |
Novel benzodiazepinnbased compound 3
|
JPS57131791A
(en)
|
1980-12-31 |
1982-08-14 |
Fujisawa Pharmaceut Co Ltd |
Benzodiazepine derivative and its preparation
|
CA1173441A
(en)
|
1981-02-27 |
1984-08-28 |
Hoffmann-La Roche Limited |
Imidazodiazepines
|
CA1184175A
(en)
|
1981-02-27 |
1985-03-19 |
Walter Hunkeler |
Imidazodiazepines
|
CA1185602A
(en)
|
1981-02-27 |
1985-04-16 |
Emilio Kyburz |
Imidazodiazepines
|
JPS58180487A
(ja)
|
1982-04-16 |
1983-10-21 |
Kyowa Hakko Kogyo Co Ltd |
抗生物質dc−81およびその製造法
|
US4427588A
(en)
|
1982-11-08 |
1984-01-24 |
Bristol-Myers Company |
Process for conversion of oxotomaymycin to tomaymycin
|
US4427587A
(en)
|
1982-11-10 |
1984-01-24 |
Bristol-Myers Company |
Total synthesis of antitumor antibiotics BBM-2040A and BBM-2040B
|
JPS59152329A
(ja)
|
1983-02-17 |
1984-08-31 |
Green Cross Corp:The |
局所障害抑制剤
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
FR2586683B1
(fr)
|
1985-08-29 |
1988-07-01 |
Centre Nat Rech Scient |
Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
|
US5583024A
(en)
|
1985-12-02 |
1996-12-10 |
The Regents Of The University Of California |
Recombinant expression of Coleoptera luciferase
|
JP2660201B2
(ja)
|
1988-08-05 |
1997-10-08 |
塩野義製薬株式会社 |
新規ピロロ[1,4]ベンゾジアゼピン誘導体および老人性痴呆薬
|
WO1991002536A1
(en)
|
1989-08-23 |
1991-03-07 |
Scripps Clinic And Research Foundation |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
JPH053790A
(ja)
|
1990-04-19 |
1993-01-14 |
Fujisawa Pharmaceut Co Ltd |
デヒドロペプチダーゼ−i
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
AU9016591A
(en)
|
1990-10-25 |
1992-05-26 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on B cells
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
EP0577752B2
(en)
|
1991-03-29 |
2007-07-11 |
Genentech, Inc. |
Human pf4a receptors and their use
|
FR2676230B1
(fr)
|
1991-05-07 |
1993-08-27 |
Centre Nat Rech Scient |
Nouveaux derives de pyrrolo [1,4]-benzodiazepines, leur procede de preparation et medicaments les contenant.
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
US5362852A
(en)
|
1991-09-27 |
1994-11-08 |
Pfizer Inc. |
Modified peptide derivatives conjugated at 2-hydroxyethylamine moieties
|
US5976551A
(en)
|
1991-11-15 |
1999-11-02 |
Institut Pasteur And Institut Nationale De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and method of using the determinant
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
GB9205051D0
(en)
|
1992-03-09 |
1992-04-22 |
Cancer Res Campaign Tech |
Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
|
FR2696176B1
(fr)
|
1992-09-28 |
1994-11-10 |
Synthelabo |
Dérivés de pipéridine, leur préparation et leur application en thérapeutique.
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
US6214345B1
(en)
|
1993-05-14 |
2001-04-10 |
Bristol-Myers Squibb Co. |
Lysosomal enzyme-cleavable antitumor drug conjugates
|
GB9316162D0
(en)
|
1993-08-04 |
1993-09-22 |
Zeneca Ltd |
Fungicides
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
EP0647450A1
(en)
|
1993-09-09 |
1995-04-12 |
BEHRINGWERKE Aktiengesellschaft |
Improved prodrugs for enzyme mediated activation
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
JPH08336393A
(ja)
|
1995-04-13 |
1996-12-24 |
Mitsubishi Chem Corp |
光学活性なγ−置換−β−ヒドロキシ酪酸エステルの製造法
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
US6218519B1
(en)
|
1996-04-12 |
2001-04-17 |
Pro-Neuron, Inc. |
Compounds and methods for the selective treatment of cancer and bacterial infections
|
EP0910636A1
(en)
|
1996-05-17 |
1999-04-28 |
Schering Corporation |
Human b-cell antigens, related reagents
|
CA2264227A1
(en)
|
1996-09-27 |
1998-04-02 |
Raymond A. Firestone |
Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
|
US6759509B1
(en)
|
1996-11-05 |
2004-07-06 |
Bristol-Myers Squibb Company |
Branched peptide linkers
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
NZ337413A
(en)
|
1997-03-10 |
2003-02-28 |
Univ California |
Antibodies that bind to Prostate Stem Cell Antigen (PSCA) to treat prostate cancer.
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
WO1998051805A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
WO1999046284A2
(en)
|
1998-03-13 |
1999-09-16 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
JP2002520000A
(ja)
|
1998-05-13 |
2002-07-09 |
エピミューン, インコーポレイテッド |
免疫応答を刺激するための発現ベクターおよびそのベクターの使用方法
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
EP1080732A4
(en)
|
1998-05-22 |
2004-08-25 |
Daiichi Seiyaku Co |
DRUG COMPOSITION
|
ATE552530T1
(de)
|
1998-07-08 |
2012-04-15 |
E Ink Corp |
Verfahren zur erzielung von verbesserten farben in mikroverkapselten elektrophoretischen vorrichtungen
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
EP1193270B1
(en)
|
1998-08-27 |
2003-05-14 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
GB9818732D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
AU5963699A
(en)
|
1998-10-02 |
2000-04-26 |
Mcmaster University |
Spliced form of (erb)b-2/neu oncogene
|
WO2001057188A2
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
CA2360396A1
(en)
|
1998-12-30 |
2000-07-13 |
Andrew M. Scharenberg |
Characterization of a calcium channel family
|
US20030187196A1
(en)
|
1998-12-30 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
DE60044665D1
(de)
|
1999-01-29 |
2010-08-26 |
Corixa Corp |
Her2/neu fusionsproteine
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
US7304126B2
(en)
|
1999-05-11 |
2007-12-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6268488B1
(en)
|
1999-05-25 |
2001-07-31 |
Barbas, Iii Carlos F. |
Prodrug activation using catalytic antibodies
|
WO2000075655A1
(fr)
|
1999-06-03 |
2000-12-14 |
Takeda Chemical Industries, Ltd. |
Procede de criblage avec cd100
|
EP2977063A1
(en)
|
1999-06-25 |
2016-01-27 |
Genentech, Inc. |
Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
|
US6302318B1
(en)
|
1999-06-29 |
2001-10-16 |
General Electric Company |
Method of providing wear-resistant coatings, and related articles
|
US7589172B2
(en)
|
1999-07-20 |
2009-09-15 |
Genentech, Inc. |
PRO256 polypeptides
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
CA2380355A1
(en)
|
1999-09-01 |
2001-03-08 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
US6750054B2
(en)
|
2000-05-18 |
2004-06-15 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
ES2309012T3
(es)
|
1999-10-29 |
2008-12-16 |
Genentech, Inc. |
Composiciones del anticuerpo anti-psca y a sus procedimientos contra celulas cancerigenas que expresen psca.
|
EP1235847B1
(en)
|
1999-11-29 |
2016-01-20 |
The Trustees of Columbia University in the City of New York |
ISOLATION OF FIVE NOVEL GENES CODING FOR NEW Fc RECEPTORS-TYPE MELANOMA INVOLVED IN THE PATHOGENESIS OF LYMPHOMA/MELANOMA
|
WO2001040269A2
(en)
|
1999-11-30 |
2001-06-07 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
EP1568373A3
(en)
|
1999-12-10 |
2005-12-21 |
Epimmune Inc. |
Inducing cellular immune responses to HER2/neu using peptide and nucleic acid compositions
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
AU2458001A
(en)
|
1999-12-23 |
2001-07-03 |
Zymogenetics Inc. |
Method for treating inflammation
|
DK1246846T3
(da)
|
1999-12-23 |
2008-12-08 |
Zymogenetics Inc |
Oplöselig interleukin-20-receptor
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
PT1240337E
(pt)
|
1999-12-24 |
2007-01-31 |
Genentech Inc |
Métodos e composições para prolongar as meias-vidas de eliminação de compostos bioactivos
|
US20040001827A1
(en)
|
2002-06-28 |
2004-01-01 |
Dennis Mark S. |
Serum albumin binding peptides for tumor targeting
|
US7294695B2
(en)
|
2000-01-20 |
2007-11-13 |
Genentech, Inc. |
PRO10268 polypeptides
|
WO2001053463A2
(en)
|
2000-01-21 |
2001-07-26 |
Corixa Corporation |
COMPOUNDS AND METHODS FOR PREVENTION AND TREATMENT OF HER-2/neu ASSOCIATED MALIGNANCIES
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
US20030186372A1
(en)
|
2000-02-11 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
WO2001062794A2
(en)
|
2000-02-22 |
2001-08-30 |
Millennium Pharmaceuticals, Inc. |
18607, a human calcium channel
|
US20040052793A1
(en)
|
2001-02-22 |
2004-03-18 |
Carter Paul J. |
Caspase activivated prodrugs therapy
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
AU2001245280A1
(en)
|
2000-03-07 |
2001-09-17 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
AU4941101A
(en)
|
2000-03-24 |
2001-10-08 |
Fahri Saatcioglu |
Novel prostate-specific or testis-specific nucleic acid molecules, polypeptides,and diagnostic and therapeutic methods
|
WO2004043361A2
(en)
|
2002-11-08 |
2004-05-27 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
WO2001072830A2
(de)
|
2000-03-31 |
2001-10-04 |
Ipf Pharmaceuticals Gmbh |
Diagnostik- und arzneimittel zur untersuchung des zelloberflächenproteoms von tumor- und entzündungszellen sowie zur behandlung von tumorerkrankungen und entzündlichen erkrankungen vorzugsweise mit hilfe einer spezifischen chemokinrezeptor-analyse und der chemokinrezeptor-ligand-interaktion
|
WO2001075177A2
(en)
|
2000-04-03 |
2001-10-11 |
The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Tumor markers in ovarian cancer
|
WO2001077172A2
(en)
|
2000-04-07 |
2001-10-18 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated known g protein-coupled receptors
|
WO2001090304A2
(en)
|
2000-05-19 |
2001-11-29 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
US20020051990A1
(en)
|
2000-06-09 |
2002-05-02 |
Eric Ople |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
CA2409776A1
(en)
|
2000-06-16 |
2001-12-27 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
WO2002002587A1
(en)
|
2000-06-30 |
2002-01-10 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
EP1294885A2
(en)
|
2000-06-30 |
2003-03-26 |
Amgen, Inc. |
B7-like molecules and uses thereof
|
JP2004528003A
(ja)
|
2000-06-30 |
2004-09-16 |
インサイト・ゲノミックス・インコーポレイテッド |
細胞外マトリクスおよび細胞接着分子
|
AU2002214531A1
(en)
|
2000-07-03 |
2002-01-30 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6891030B2
(en)
|
2000-07-27 |
2005-05-10 |
Mayo Foundation For Medical Education And Research |
T-cell immunoregulatory molecule
|
EP1366158B1
(en)
|
2000-07-28 |
2008-05-21 |
Ulrich Wissenbach |
Trp8 markers for cancer
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
US20020193329A1
(en)
|
2000-08-14 |
2002-12-19 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of Her-2/neu-associated malignancies
|
WO2002013847A2
(en)
|
2000-08-14 |
2002-02-21 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
JP2004520806A
(ja)
|
2000-08-24 |
2004-07-15 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断と治療のための組成物と方法
|
EP1346040A2
(en)
|
2000-09-11 |
2003-09-24 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
WO2002022153A2
(en)
|
2000-09-15 |
2002-03-21 |
Zymogenetics, Inc. |
Use of a polypeptide comprising the extracellular domains of il-20rb for the treatment of inflammation
|
US20060073551A1
(en)
|
2000-09-15 |
2006-04-06 |
Genentech, Inc. |
Pro4487 polypeptides
|
AU2001292724B2
(en)
|
2000-09-18 |
2005-05-26 |
Biogen Idec Ma Inc. |
CRIPTO mutant and uses thereof
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
EP1320522B8
(en)
|
2000-09-19 |
2006-02-01 |
Moses Lee |
Compositions and methods of the use thereof achiral analogues of cc-1065 and the duocarmycins
|
WO2002030268A2
(en)
|
2000-10-13 |
2002-04-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
|
ATE432986T1
(de)
|
2000-11-07 |
2009-06-15 |
Zymogenetics Inc |
Menschlicher rezeptor für tumor necrosis factor
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
US20040018194A1
(en)
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
EP1357828A2
(en)
|
2001-01-12 |
2003-11-05 |
University of Medicine and Dentistry of New Jersey |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
US20030119133A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US20030119119A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
JP2005503760A
(ja)
|
2001-01-24 |
2005-02-10 |
プロテイン デザイン ラブス, インコーポレイテッド |
乳癌の診断方法、組成物および乳癌のモジュレーターのスクリーニング方法
|
US20030073144A1
(en)
|
2001-01-30 |
2003-04-17 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
WO2002064798A1
(en)
|
2001-02-12 |
2002-08-22 |
Bionomics Limited |
Dna sequences differentially expressed in tumour cell lines
|
WO2002071928A2
(en)
|
2001-03-14 |
2002-09-19 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
EP1243276A1
(en)
|
2001-03-23 |
2002-09-25 |
Franciscus Marinus Hendrikus De Groot |
Elongated and multiple spacers containing activatible prodrugs
|
US20040236091A1
(en)
|
2001-03-28 |
2004-11-25 |
Chicz Roman M. |
Translational profiling
|
US6362331B1
(en)
|
2001-03-30 |
2002-03-26 |
Council Of Scientific And Industrial Research |
Process for the preparation of antitumor agents
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
EP1414477B1
(en)
|
2001-04-17 |
2015-06-10 |
The Board Of Trustees Of The University Of Arkansas |
Repeat sequences of the ca125 gene and their use for diagnostic interventions
|
EP1463928A2
(en)
|
2001-04-18 |
2004-10-06 |
Protein Design Labs |
Methods of diagnosis of lung cancer, compositions and methods of screening for modulators of lung cancer
|
RS51635B
(sr)
|
2001-04-26 |
2011-08-31 |
Biogen Idec Ma Inc. |
Antitela koja blokiraju cripto i njihova upotreba
|
US6884869B2
(en)
|
2001-04-30 |
2005-04-26 |
Seattle Genetics, Inc. |
Pentapeptide compounds and uses related thereto
|
WO2002089747A2
(en)
|
2001-05-09 |
2002-11-14 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
AU2002344326A1
(en)
|
2001-05-11 |
2002-11-25 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
DE60234202D1
(de)
|
2001-05-24 |
2009-12-10 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
WO2003000842A2
(en)
|
2001-06-04 |
2003-01-03 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
AU2002314901A1
(en)
|
2001-06-04 |
2002-12-16 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
ATE483976T1
(de)
|
2001-06-05 |
2010-10-15 |
Exelixis Inc |
Gfats als modifikatoren des p53-wegs und verwendungsverfahren
|
AU2002310256A1
(en)
|
2001-06-05 |
2002-12-16 |
Exelixis Inc. |
Ppp2cs as modifiers of the p53 pathway and methods of use
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
WO2002101075A2
(en)
|
2001-06-13 |
2002-12-19 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
JP2005508144A
(ja)
|
2001-06-18 |
2005-03-31 |
イオス バイオテクノロジー,インコーポレイティド |
卵巣癌の診断方法、卵巣癌のモジュレーターをスクリーニングする組成物及び方法
|
AU2002322280A1
(en)
|
2001-06-21 |
2003-01-21 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
US20030108958A1
(en)
|
2001-06-28 |
2003-06-12 |
Rene De Waal Malefyt |
Biological activity of AK155
|
US20030120040A1
(en)
|
2001-06-29 |
2003-06-26 |
Genentech, Inc. |
Secreted and Transmembrane polypeptides and nucleic acids encoding the same
|
WO2003004529A2
(en)
|
2001-07-02 |
2003-01-16 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
US7446185B2
(en)
|
2001-07-18 |
2008-11-04 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
US20030108963A1
(en)
|
2001-07-25 |
2003-06-12 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer
|
JP2005510208A
(ja)
|
2001-08-03 |
2005-04-21 |
ジェネンテック・インコーポレーテッド |
TACIs及びBR3ポリペプチドとその用途
|
AU2002324700A1
(en)
|
2001-08-14 |
2003-03-03 |
Bayer Ag |
Nucleic acid and amino acid sequences involved in pain
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
AU2002313559A1
(en)
|
2001-08-23 |
2003-03-10 |
Oxford Biomedica (Uk) Limited |
Genes
|
AU2002357643A1
(en)
|
2001-08-29 |
2003-04-14 |
Vanderbilt University |
The human mob-5 (il-24) receptors and uses thereof
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
WO2003022995A2
(en)
|
2001-09-06 |
2003-03-20 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled steap-1 useful in treatment and detection of cancer
|
AU2002330039A1
(en)
|
2001-09-17 |
2003-04-01 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
US20050004017A1
(en)
|
2001-09-18 |
2005-01-06 |
Yuval Reiss |
Methods and compositions for treating hcap associated diseases
|
EP2143438B1
(en)
|
2001-09-18 |
2011-07-13 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumors
|
CA2460621A1
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
WO2003026577A2
(en)
|
2001-09-24 |
2003-04-03 |
Seattle Genetics, Inc. |
P-amidobenzylethers in drug delivery agents
|
US7091186B2
(en)
|
2001-09-24 |
2006-08-15 |
Seattle Genetics, Inc. |
p-Amidobenzylethers in drug delivery agents
|
AU2002327792A1
(en)
|
2001-09-28 |
2003-04-07 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in cd72
|
AU2002362436A1
(en)
|
2001-10-03 |
2003-04-14 |
Rigel Pharmaceuticals, Inc. |
Modulators of lymphocyte activation and migration
|
AU2002362454A1
(en)
|
2001-10-03 |
2003-04-14 |
Origene Technologies, Inc. |
Regulated breast cancer genes
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
US20040241703A1
(en)
|
2002-08-19 |
2004-12-02 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
JP2005522986A
(ja)
|
2001-10-19 |
2005-08-04 |
ジェネンテック・インコーポレーテッド |
炎症性腸疾患の診断と治療のための組成物と方法
|
AU2002356858A1
(en)
|
2001-10-24 |
2003-05-06 |
National Jewish Medical And Research Center |
Structure of tall-1 and its cognate receptor
|
JP4255382B2
(ja)
|
2001-10-31 |
2009-04-15 |
アルコン,インコーポレイテッド |
骨形成タンパク質(bmp)、bmpレセプターおよびbmp結合タンパク質ならびに緑内障の診断および処置におけるそれらの使用
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
EP1482972A4
(en)
|
2001-11-20 |
2005-11-23 |
Seattle Genetics Inc |
TREATMENT OF IMMUNOLOGICAL DISORDERS USING ANTI-CD30 ANTIBODIES
|
US7344843B2
(en)
|
2001-11-29 |
2008-03-18 |
Serono Genetics Institute S.A. |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
AU2002349784A1
(en)
|
2001-12-03 |
2003-06-17 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
DK1461428T3
(da)
|
2001-12-03 |
2012-06-04 |
Alexion Pharma Inc |
Fremgangsmåde til at fremstille hybridantistoffer
|
EP1504099A4
(en)
|
2001-12-10 |
2006-05-10 |
Nuvelo Inc |
NEW NUCLEIC ACIDS AND POLYPEPTIDES
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
US20050041271A1
(en)
|
2002-01-16 |
2005-02-24 |
Ito Tomoyoshi |
Moving image holography reproducing device and color moving image holography reproducing device
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
AU2003224624B2
(en)
|
2002-02-21 |
2008-08-28 |
Duke University |
Reagents and treatment methods for autoimmune diseases
|
EP2388265A1
(en)
|
2002-02-22 |
2011-11-23 |
Genentech, Inc. |
Compositions and methods for the treatment of immune related diseases
|
AU2003213606A1
(en)
|
2002-03-01 |
2003-10-13 |
Exelixis, Inc. |
MP53s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
US20050287147A1
(en)
|
2002-05-15 |
2005-12-29 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
US6660856B2
(en)
|
2002-03-08 |
2003-12-09 |
Kaohsiung Medical University |
Synthesis of pyrrolo[2,1-c][1,4]benzodiazepine analogues
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
CA2486490A1
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
WO2003081210A2
(en)
|
2002-03-21 |
2003-10-02 |
Sunesis Pharmaceuticals, Inc. |
Identification of kinase inhibitors
|
EP1494693B1
(en)
|
2002-03-22 |
2010-12-08 |
Biogen Idec MA Inc. |
Cripto-specific antibodies
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
AU2003245239A1
(en)
|
2002-03-25 |
2003-11-03 |
Uab Research Foundation |
FC receptor homolog, reagents, and uses thereof
|
AU2003222103A1
(en)
|
2002-03-28 |
2003-10-13 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
JP2005534287A
(ja)
|
2002-04-05 |
2005-11-17 |
アジェンシス, インコーポレイテッド |
癌の処置および検出において有用な98p4b6との名称の核酸および対応するタンパク質
|
US20040101874A1
(en)
|
2002-04-12 |
2004-05-27 |
Mitokor Inc. |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
KR20040101502A
(ko)
|
2002-04-16 |
2004-12-02 |
제넨테크, 인크. |
종양의 진단 및 치료 방법 및 이를 위한 조성물
|
WO2003089904A2
(en)
|
2002-04-17 |
2003-10-30 |
Baylor College Of Medicine |
Aib1 as a prognostic marker and predictor of resistance to encocrine therapy
|
WO2003093444A2
(en)
|
2002-05-03 |
2003-11-13 |
Incyte Corporation |
Transporters and ion channels
|
WO2003101388A2
(en)
|
2002-05-30 |
2003-12-11 |
Bristol-Myers Squibb Company |
Human solute carrier family 7 member 11 (hslc7a11)
|
WO2003101283A2
(en)
|
2002-06-04 |
2003-12-11 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
CA2488284A1
(en)
|
2002-06-04 |
2003-12-11 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
WO2003104270A2
(en)
|
2002-06-06 |
2003-12-18 |
Ingenium Pharmaceuticals Ag |
Dudulin 2 genes, expression products, non-human animal model: uses in human hematological disease
|
DK1513934T3
(da)
|
2002-06-06 |
2011-05-02 |
Oncotherapy Science Inc |
Gener og polypeptider relateret til humane coloncancersygdomme
|
US20060228705A1
(en)
|
2002-06-07 |
2006-10-12 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
WO2003105758A2
(en)
|
2002-06-12 |
2003-12-24 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
US20040022727A1
(en)
|
2002-06-18 |
2004-02-05 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
AU2003245615A1
(en)
|
2002-06-20 |
2004-01-06 |
The Regents Of The University Of California |
Compositions and methods for modulating lymphocyte activity
|
EP2365004B1
(en)
|
2002-06-21 |
2016-01-06 |
Johns Hopkins University School of Medicine |
Membrane associated tumor endothelium markers
|
DE10229834A1
(de)
|
2002-07-03 |
2004-01-29 |
Zinser Textilmaschinen Gmbh |
Streckwerk für Spinnmaschinen mit nachgeordneter Verdichtungsvorrichtung
|
AU2003281515A1
(en)
|
2002-07-19 |
2004-02-09 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
JP2005533863A
(ja)
|
2002-07-25 |
2005-11-10 |
ジェネンテック・インコーポレーテッド |
Taci抗体とその用途
|
AU2003263964C1
(en)
|
2002-07-31 |
2010-08-19 |
Seagen Inc. |
Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease
|
US20050180972A1
(en)
|
2002-07-31 |
2005-08-18 |
Wahl Alan F. |
Anti-CD20 antibody-drug conjugates for the treatment of cancer and immune disorders
|
AU2003251471A1
(en)
|
2002-08-06 |
2004-02-25 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
WO2004020583A2
(en)
|
2002-08-27 |
2004-03-11 |
Bristol-Myers Squibb Company |
Polynucleotide predictor set for identifying protein tyrosine kinase modulators
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
WO2004019993A1
(en)
|
2002-08-30 |
2004-03-11 |
Ramot At Tel Aviv University Ltd. |
Self-immolative dendrimers releasing many active moieties upon a single activating event
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
US20040180354A1
(en)
|
2002-09-06 |
2004-09-16 |
Simard John J.L. |
Epitope sequences
|
AU2003300776A1
(en)
|
2002-09-09 |
2004-05-25 |
Omeros Corporation |
G protein coupled receptors and uses thereof
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
EP1554309A2
(en)
|
2002-10-03 |
2005-07-20 |
McGILL UNIVERSITY |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
EP1570078A4
(en)
|
2002-10-04 |
2006-09-13 |
Van Andel Res Inst |
MOLECULAR CLASSIFICATION OF RENAL TUMORS AND DISCOVERING NEW DIAGNOSTIC MARKERS
|
US20040138269A1
(en)
|
2002-10-11 |
2004-07-15 |
Sugen, Inc. |
Substituted pyrroles as kinase inhibitors
|
AU2003295511A1
(en)
|
2002-11-13 |
2004-06-03 |
Genentech, Inc. |
Methods and compositions for diagnosing dysplasia
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
EP1560599A1
(en)
|
2002-11-14 |
2005-08-10 |
Syntarga B.V. |
Prodrugs built as multiple self-elimination-release spacers
|
US8007804B2
(en)
|
2002-11-15 |
2011-08-30 |
Musc Foundation For Research Development |
Complement receptor 2 targeted complement modulators
|
CN101124244B
(zh)
*
|
2002-11-15 |
2012-10-10 |
根马布股份公司 |
抗cd25的人单克隆抗体
|
AU2003294355A1
(en)
|
2002-11-15 |
2004-06-15 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
WO2004046342A2
(en)
|
2002-11-20 |
2004-06-03 |
Biogen Idec Inc. |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of carcinomas
|
AU2003294462C1
(en)
|
2002-11-21 |
2011-06-30 |
University Of Utah Research Foundation |
Purinergic modulation of smell
|
US20040253606A1
(en)
|
2002-11-26 |
2004-12-16 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
WO2004053079A2
(en)
|
2002-12-06 |
2004-06-24 |
Diadexus, Inc. |
Compositions, splice variants and methods relating to ovarian specific genes and proteins
|
US20040157278A1
(en)
|
2002-12-13 |
2004-08-12 |
Bayer Corporation |
Detection methods using TIMP 1
|
EP1581171B1
(en)
|
2002-12-20 |
2012-06-27 |
Abbott Biotherapeutics Corp. |
Antibodies against gpr64 and uses thereof
|
WO2004058309A1
(en)
|
2002-12-23 |
2004-07-15 |
Human Genome Sciences, Inc. |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
WO2004063709A2
(en)
|
2003-01-08 |
2004-07-29 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
US20050181375A1
(en)
|
2003-01-10 |
2005-08-18 |
Natasha Aziz |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of metastatic cancer
|
WO2004065577A2
(en)
|
2003-01-14 |
2004-08-05 |
Bristol-Myers Squibb Company |
Polynucleotides and polypeptides associated with the nf-kb pathway
|
WO2004065576A2
(en)
|
2003-01-15 |
2004-08-05 |
Millennium Pharmaceuticals, Inc. |
Methods and compositions for the treatment of urological disorder using differential expressed polypeptides
|
WO2004074320A2
(en)
|
2003-02-14 |
2004-09-02 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
DE60326060D1
(de)
|
2003-03-31 |
2009-03-19 |
Council Scient Ind Res |
Nichtvernetzende pyrroloä2,1-cüä1,4übenzodiazepine als potentielle antitumor-agentien und ihre herstellung
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
GB0416511D0
(en)
|
2003-10-22 |
2004-08-25 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
ATE516288T1
(de)
|
2003-10-22 |
2011-07-15 |
Us Gov Health & Human Serv |
Pyrrolobenzodiazepinderivate, zusammensetzungen, die diese enthalten, und damit in zusammenhang stehende verfahren
|
PT1725249E
(pt)
|
2003-11-06 |
2014-04-10 |
Seattle Genetics Inc |
Compostos de monometilvalina capazes de conjugação a ligandos
|
US20050288491A1
(en)
|
2004-02-17 |
2005-12-29 |
Wilson David S |
Super-humanized antibodies against respiratory syncytial virus
|
EP1718667B1
(en)
|
2004-02-23 |
2013-01-09 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0404574D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Amino acids
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
DK2270010T3
(da)
|
2004-03-01 |
2012-05-14 |
Spirogen Ltd |
11-hydroxy-5h-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-derivater som vigtige mellemprodukter i fremstillingen af c2-substituerede pyrrolobenzodiazepiner
|
DE102004010943A1
(de)
|
2004-03-03 |
2005-09-29 |
Degussa Ag |
Verfahren zur Herstellung von N-geschützten 4-Ketprolinderivaten
|
US7528126B2
(en)
|
2004-03-09 |
2009-05-05 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
FR2869231B1
(fr)
|
2004-04-27 |
2008-03-14 |
Sod Conseils Rech Applic |
Composition therapeutique contenant au moins un derive de la pyrrolobenzodiazepine et la fludarabine
|
GB0410725D0
(en)
|
2004-05-13 |
2004-06-16 |
Spirogen Ltd |
Pyrrolobenzodiazepine therapeutic agents
|
DK1791565T3
(en)
|
2004-09-23 |
2016-08-01 |
Genentech Inc |
Cysteingensplejsede antibodies and conjugates
|
RU2364643C2
(ru)
|
2004-12-24 |
2009-08-20 |
Сова Денко К.К. |
Способ получения термоэлектрического полупроводникового сплава, модуль термоэлектрического преобразования и термоэлектрическое устройство генерации электроэнергии
|
DK1844074T3
(da)
|
2005-02-03 |
2013-07-15 |
Antitope Ltd |
Humane antistoffer og proteiner
|
DK1871418T3
(da)
|
2005-04-19 |
2014-06-10 |
Seattle Genetics Inc |
Humaniserede anti-cd70-bindende midler og anvendelser deraf
|
US7612062B2
(en)
|
2005-04-21 |
2009-11-03 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
DE602006006199D1
(de)
|
2005-10-05 |
2009-05-20 |
Spirogen Ltd |
4-ä4-(5-oxo-2,3,5,11a-tetrahydro-5h-pyrrolo ä2, 1-cüä1,4übenzodiazepin-8-yloxy)-butyrylaminoü-1h-pyrrol-2-carbonsäurealkylesterderivate und verwandte verbindung zur behandlung einer proliferativen erkrankung
|
CN110668988A
(zh)
|
2005-10-07 |
2020-01-10 |
埃克塞利希斯股份有限公司 |
作为用于治疗增生性疾病的mek抑制剂的吖丁啶
|
DK2270050T3
(da)
|
2005-12-30 |
2013-08-12 |
Merck Patent Gmbh |
Anti-CD19-antistoffer med nedsat immunogenicitet
|
ES2374964T3
(es)
|
2006-01-25 |
2012-02-23 |
Sanofi |
Agentes citotóxicos que comprenden nuevos derivados de tomaimicina.
|
CA2658276A1
(en)
|
2006-07-18 |
2008-01-24 |
Sanofi-Aventis |
Antagonist antibody for the treatment of cancer
|
WO2008022152A2
(en)
|
2006-08-14 |
2008-02-21 |
Xencor, Inc. |
Optimized antibodies that target cd19
|
US20080112961A1
(en)
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
ES2523915T5
(es)
|
2006-12-01 |
2022-05-26 |
Seagen Inc |
Agentes de unión a la diana variantes y usos de los mismos
|
CA2673771A1
(en)
*
|
2007-01-17 |
2008-07-24 |
Merck Serono S.A. |
Process for the purification of fc-containing proteins
|
CN101687037B
(zh)
|
2007-05-08 |
2013-07-10 |
健泰科生物技术公司 |
半胱氨酸改造的抗muc16抗体和抗体药物偶联物
|
PL2019104T3
(pl)
|
2007-07-19 |
2014-03-31 |
Sanofi Sa |
Środki cytotoksyczne obejmujące nowe pochodne tomaymycyny i ich zastosowanie terapeutyczne
|
AU2008312457B2
(en)
|
2007-10-19 |
2014-04-17 |
Genentech, Inc. |
Cysteine engineered anti-TENB2 antibodies and antibody drug conjugates
|
EP2842575B1
(en)
|
2008-03-18 |
2017-09-27 |
Seattle Genetics, Inc. |
Auristatin drug linker conjugates
|
GB0813432D0
(en)
|
2008-07-22 |
2008-08-27 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
US8668695B2
(en)
|
2008-10-15 |
2014-03-11 |
Zimmer Gmbh |
Intramedullary nail
|
GB0819097D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
AU2010210646B2
(en)
*
|
2009-02-05 |
2015-10-29 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
EP2398829A2
(en)
|
2009-02-23 |
2011-12-28 |
Glenmark Pharmaceuticals S.A. |
Humanized antibodies that bind to cd19 and their uses
|
FR2949469A1
(fr)
|
2009-08-25 |
2011-03-04 |
Sanofi Aventis |
Derives anticancereux, leur preparation et leur application en therapeutique
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
US20110070248A1
(en)
|
2009-09-24 |
2011-03-24 |
Seattle Genetics, Inc. |
Dr5 ligand drug conjugates
|
EP2534158B1
(en)
|
2010-02-09 |
2014-01-08 |
Bristol-Myers Squibb Company |
Benzylpyrrolidinone derivatives as modulators of chemokine receptor activity
|
WO2011130616A1
(en)
|
2010-04-15 |
2011-10-20 |
Spirogen Limited |
Pyrrolobenzodiazepines used to treat proliferative diseases
|
KR101772354B1
(ko)
|
2010-04-15 |
2017-08-28 |
시애틀 지네틱스, 인크. |
표적화된 피롤로벤조디아제핀 접합체
|
WO2011130615A2
(en)
|
2010-04-15 |
2011-10-20 |
Dr. Reddy's Laboratories Ltd. |
Preparation of lacosamide
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
SI2528625T1
(sl)
|
2010-04-15 |
2013-11-29 |
Spirogen Sarl |
Pirolobenzodiazepini in njihovi konjugati
|
KR20140010067A
(ko)
|
2011-02-15 |
2014-01-23 |
이뮤노젠 아이엔씨 |
컨쥬게이트의 제조방법
|
US9399641B2
(en)
|
2011-09-20 |
2016-07-26 |
Medimmune Limited |
Pyrrolobenzodiazepines as unsymmetrical dimeric PBD compounds for inclusion in targeted conjugates
|
BR112014009055B1
(pt)
|
2011-10-14 |
2021-12-14 |
Seattle Genetics, Inc. |
Compostos pirrolobenzodiazepinas, conjugados alvos, ligante de fármaco e uso dos ditos conjugados para tratar uma doença proliferativa
|
CA2850103C
(en)
|
2011-10-14 |
2019-09-10 |
Spirogen Sarl |
Pyrrolobenzodiazepines
|
AU2012322932B2
(en)
|
2011-10-14 |
2016-11-10 |
Medimmune Limited |
Pyrrolobenzodiazepines
|
AU2012322607B2
(en)
|
2011-10-14 |
2017-02-16 |
Genentech, Inc. |
Pyrrolobenzodiazepines and conjugates thereof
|
CN103987384A
(zh)
|
2011-10-14 |
2014-08-13 |
西雅图基因公司 |
吡咯并苯并二氮杂卓和靶向结合物
|
EP2751076B1
(en)
|
2011-10-14 |
2018-04-25 |
MedImmune Limited |
Synthesis method and intermediates useful in the preparation of pyrrolobenzodiazepines
|
EA201590171A1
(ru)
|
2012-07-09 |
2015-09-30 |
Дженентек, Инк. |
ИММУНОКОНЪЮГАТЫ, СОДЕРЖАЩИЕ АНТИТЕЛА К CD79b
|
PE20150615A1
(es)
|
2012-07-09 |
2015-05-28 |
Genentech Inc |
Inmunoconjugados que comprenden un anticuerpo anti-cd22 ligado a una pirrolobenzodiazepina
|
MX2015001399A
(es)
|
2012-08-02 |
2015-09-07 |
Genentech Inc |
Anticuerpos anti-etbr e inmunoconjugados.
|
TR201902494T4
(tr)
|
2012-10-12 |
2019-03-21 |
Medimmune Ltd |
Pirrolobenzodiazepinler ve onların konjugatları.
|
HUE039329T2
(hu)
*
|
2012-10-12 |
2018-12-28 |
Adc Therapeutics Sa |
Pirrolobenzodiazepin-antitest konjugátumok
|
JP6367204B2
(ja)
|
2012-10-12 |
2018-08-01 |
メドイミューン・リミテッドMedImmune Limited |
結合用のピロロベンゾジアゼピン誘導体の合成および中間体
|
HUE045435T2
(hu)
*
|
2012-10-12 |
2019-12-30 |
Medimmune Ltd |
Pirrolobenzodiazepinek és konjugátumaik
|
MX363787B
(es)
|
2013-03-13 |
2019-04-03 |
Medimmune Ltd |
Pirrolobenzodiazepinas y conjugados de los mismos.
|
BR112017011111A2
(pt)
*
|
2014-11-25 |
2017-12-26 |
Adc Therapeutics Sa |
conjugados de pirrolobenzodiazepina-anticorpo
|
AU2018253950A1
(en)
*
|
2017-04-20 |
2019-09-19 |
Adc Therapeutics Sa |
Combination therapy with an anti-CD25 antibody-drug conjugate
|