SI1309581T1 - Method for the preparation of citalopram - Google Patents

Method for the preparation of citalopram

Info

Publication number
SI1309581T1
SI1309581T1 SI200130273T SI200130273T SI1309581T1 SI 1309581 T1 SI1309581 T1 SI 1309581T1 SI 200130273 T SI200130273 T SI 200130273T SI 200130273 T SI200130273 T SI 200130273T SI 1309581 T1 SI1309581 T1 SI 1309581T1
Authority
SI
Slovenia
Prior art keywords
citalopram
preparation
Prior art date
Application number
SI200130273T
Other languages
English (en)
Slovenian (sl)
Inventor
Hans Petersen
Haleh Ahmadian
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of SI1309581T1 publication Critical patent/SI1309581T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
SI200130273T 2000-08-18 2001-08-14 Method for the preparation of citalopram SI1309581T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200001231 2000-08-18
PCT/DK2001/000541 WO2002016341A1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram
EP01957785A EP1309581B1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Publications (1)

Publication Number Publication Date
SI1309581T1 true SI1309581T1 (en) 2005-04-30

Family

ID=8159660

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200130273T SI1309581T1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram
SI200130272T SI1309582T1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200130272T SI1309582T1 (en) 2000-08-18 2001-08-14 Method for the preparation of citalopram

Country Status (41)

Country Link
US (2) US6426422B1 (cs)
EP (2) EP1309582B1 (cs)
JP (2) JP2004506729A (cs)
KR (2) KR100887206B1 (cs)
CN (3) CN1159307C (cs)
AR (3) AR029597A1 (cs)
AT (4) ATE281448T1 (cs)
AU (6) AU2001279609B2 (cs)
BE (2) BE1013443A6 (cs)
BG (2) BG65965B1 (cs)
CA (2) CA2354880C (cs)
CH (2) CH691969A5 (cs)
CL (2) CL2008002412A1 (cs)
CZ (2) CZ295863B6 (cs)
DE (4) DE60106933T2 (cs)
DK (4) DK200101219A (cs)
EA (2) EA005946B1 (cs)
ES (4) ES2230347T3 (cs)
FI (2) FI20011622L (cs)
FR (2) FR2813078B1 (cs)
GB (2) GB2365865B (cs)
GR (1) GR1004074B (cs)
HK (2) HK1044538B (cs)
HR (2) HRP20030065A2 (cs)
HU (2) HUP0103291A3 (cs)
IE (2) IES20010760A2 (cs)
IL (2) IL144816A (cs)
IS (2) IS2121B (cs)
ME (2) MEP2308A (cs)
MX (2) MXPA03000913A (cs)
NL (2) NL1018775C1 (cs)
NO (2) NO326772B1 (cs)
NZ (2) NZ523877A (cs)
PL (2) PL359825A1 (cs)
PT (2) PT1309581E (cs)
RS (2) RS50287B (cs)
SI (2) SI1309581T1 (cs)
SK (2) SK287008B6 (cs)
UA (2) UA71676C2 (cs)
WO (2) WO2002016342A1 (cs)
ZA (1) ZA200106683B (cs)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) * 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
KR100505820B1 (ko) 1999-10-25 2005-08-03 하. 룬트벡 아크티에 셀스카브 시탈로프람의 제조방법
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
ATE261953T1 (de) 1999-12-28 2004-04-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
AU1858400A (en) 1999-12-30 2001-07-16 H. Lundbeck A/S Method for the preparation of citalopram
DK1254129T3 (da) * 2000-01-14 2004-03-29 Lundbeck & Co As H Fremgangsmåde til fremstilling af 5-cyanophthalid
IES20010157A2 (en) 2000-03-03 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CZ20023100A3 (cs) * 2000-03-13 2003-02-12 H. Lundbeck A/S Způsob výroby citalopramu
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
HRP20020744A2 (en) 2000-03-13 2004-12-31 Lundbeck & Co As H Method for the preparation of citalopram
DK1265882T3 (da) 2000-03-14 2004-06-01 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
CZ20023406A3 (cs) * 2000-03-16 2003-01-15 H. Lundbeck A/S Způsob výroby 5-kyano-1-(4-fluorfenyl)-1,3-dihydroisobenzofuranu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
WO2003057132A2 (en) * 2002-01-07 2003-07-17 Sun Pharmaceutical Industries Limited Process for the preparation of 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
TWI306846B (en) * 2002-08-12 2009-03-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
US9339500B2 (en) * 2008-03-04 2016-05-17 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms
US20100087664A1 (en) * 2008-10-07 2010-04-08 Ravindra Vedantham Preparation of citalopram and salts thereof
JP6222973B2 (ja) * 2013-04-19 2017-11-01 日本テルペン化学株式会社 ジベンジルトリチオカーボネート誘導体
CN103936702A (zh) * 2014-05-07 2014-07-23 成都诺维尔生物医药有限公司 艾司西酞普兰杂质j的合成方法
WO2016058896A1 (en) * 2014-10-14 2016-04-21 Syngenta Participations Ag Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (cs) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE3926765A1 (de) 1989-08-12 1991-02-14 Hoechst Ag Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
CN1206207C (zh) 1997-07-08 2005-06-15 H.隆德贝克有限公司 氰酞氟苯胺的制备方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
EP1042310B1 (en) 1997-11-11 2002-07-31 H. Lundbeck A/S Method for the preparation of citalopram
CZ299920B6 (cs) 1998-10-20 2008-12-29 H. Lundbeck A/S Zpusob výroby citalopramu
PL203275B1 (pl) 1998-12-23 2009-09-30 Lundbeck & Co As H Sposób wytwarzania 5-cyjanoftalidu
AR022329A1 (es) * 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DK1173431T4 (da) 1999-04-14 2010-01-04 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
FR2805812A1 (fr) 2000-02-24 2001-09-07 Lundbeck & Co As H Procede de preparation du citalopram
IES20010143A2 (en) 2000-02-24 2001-07-25 Lundbeck & Co As H Method for the preparation of citalopram
GB0005477D0 (en) * 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
WO2001045483A2 (en) 2000-12-22 2001-06-28 H. Lundbeck A/S Method for the preparation of pure citalopram
BR0106271A (pt) 2000-12-28 2002-05-21 Lundbeck & Co As H Processo para preparação de citalopram puro

Also Published As

Publication number Publication date
RS50258B (sr) 2009-07-15
ATE281447T1 (de) 2004-11-15
DK200101216A (da) 2002-02-19
DE60106933T2 (de) 2005-12-01
CN1159307C (zh) 2004-07-28
SK287008B6 (sk) 2009-09-07
CA2354877A1 (en) 2002-02-18
HUP0103295A3 (en) 2005-01-28
AT4946U1 (de) 2002-01-25
ATE281448T1 (de) 2004-11-15
UA71676C2 (en) 2004-12-15
GB2362647A (en) 2001-11-28
IS2121B (is) 2006-06-15
IS6047A (is) 2001-10-20
EA005811B1 (ru) 2005-06-30
CH691969A5 (de) 2001-12-14
NL1018776C1 (nl) 2001-10-24
HRP20030064A2 (en) 2005-02-28
EA200300279A1 (ru) 2003-08-28
ES2170735A1 (es) 2002-08-01
HUP0103291A3 (en) 2003-02-28
ES2170734A1 (es) 2002-08-01
BG65965B1 (bg) 2010-07-30
IS2120B (is) 2006-06-15
BE1013443A6 (fr) 2002-01-15
AU2001100278B4 (en) 2001-11-29
CN1515564A (zh) 2004-07-28
GB0119733D0 (en) 2001-10-03
DE60106932T2 (de) 2005-11-03
AU7960901A (en) 2002-03-04
HU0103291D0 (en) 2001-10-28
MEP2308A (xx) 2010-02-10
CN1239490C (zh) 2006-02-01
BE1013444A6 (fr) 2002-01-15
FR2813078A1 (fr) 2002-02-22
HK1068069A1 (en) 2005-04-22
SK3202003A3 (en) 2003-08-05
CH691968A5 (de) 2001-12-14
NO326570B1 (no) 2009-01-12
IES20010761A2 (en) 2002-02-20
MXPA03000913A (es) 2003-06-24
NZ523853A (en) 2004-07-30
GB2362647B (en) 2002-09-18
PL359825A1 (pl) 2004-09-06
NO326772B1 (no) 2009-02-16
NO20013943L (no) 2002-02-19
AU2001100271B4 (en) 2001-11-29
HK1044538A1 (en) 2002-10-25
IL144817A0 (en) 2002-06-30
HUP0103295A2 (hu) 2002-05-29
EP1309582B1 (en) 2004-11-03
NL1018775C1 (nl) 2001-10-24
CL2008002412A1 (es) 2009-01-02
NO20013943D0 (no) 2001-08-14
FR2813077B1 (fr) 2004-08-20
ES2228920T3 (es) 2005-04-16
CL2008002673A1 (es) 2009-01-02
DE60106933D1 (de) 2004-12-09
WO2002016341A1 (en) 2002-02-28
CN1222517C (zh) 2005-10-12
AT5026U1 (de) 2002-02-25
PL359969A1 (en) 2004-09-06
US6426422B1 (en) 2002-07-30
UA72340C2 (uk) 2005-02-15
US20020026062A1 (en) 2002-02-28
US20020025982A1 (en) 2002-02-28
WO2002016342A1 (en) 2002-02-28
KR20030022385A (ko) 2003-03-15
HK1044538B (zh) 2006-07-07
HUP0103291A2 (hu) 2002-05-29
MXPA03001329A (es) 2003-06-06
GB2365865A (en) 2002-02-27
ES2230347T3 (es) 2005-05-01
IES20010760A2 (en) 2002-02-20
KR100887206B1 (ko) 2009-03-06
DE10140028A1 (de) 2002-04-18
CZ20012959A3 (cs) 2002-04-17
GR1004074B (el) 2002-11-26
FI20011622A7 (fi) 2002-02-19
HRP20030065A2 (en) 2005-02-28
EA005946B1 (ru) 2005-08-25
PT1309582E (pt) 2005-03-31
CZ20012958A3 (cs) 2002-04-17
CZ295863B6 (cs) 2005-11-16
SI1309582T1 (en) 2005-06-30
DE60106932D1 (de) 2004-12-09
KR100887207B1 (ko) 2009-03-06
EP1309581A1 (en) 2003-05-14
CA2354880C (en) 2003-06-03
NO20013942L (no) 2002-02-19
US6509483B2 (en) 2003-01-21
AR029598A1 (es) 2003-07-10
AU2001279609B2 (en) 2007-09-06
ES2170734B2 (es) 2003-09-16
DE10140029A1 (de) 2002-05-02
IS6048A (is) 2001-10-19
CN1339436A (zh) 2002-03-13
FI20011622A0 (fi) 2001-08-09
HK1047086B (zh) 2005-04-22
RS50287B (sr) 2009-09-08
YU6903A (sh) 2006-05-25
KR20030022378A (ko) 2003-03-15
AU7960801A (en) 2002-03-04
BG65964B1 (bg) 2010-07-30
NO20013942D0 (no) 2001-08-14
IL144816A (en) 2005-09-25
BG107583A (bg) 2004-01-30
FR2813077A1 (fr) 2002-02-22
YU11503A (sh) 2006-05-25
CA2354880A1 (en) 2002-01-22
DK1309582T3 (da) 2005-03-14
EA200300277A1 (ru) 2003-08-28
MEP2208A (xx) 2010-02-10
IL144816A0 (en) 2002-06-30
AU2001100278A4 (en) 2001-09-13
AR066694A2 (es) 2009-09-09
PT1309581E (pt) 2005-03-31
JP2004506729A (ja) 2004-03-04
FI20011622L (fi) 2002-02-19
AU2001279608B2 (en) 2006-10-05
GB2365865B (en) 2002-07-17
ZA200106683B (en) 2002-08-05
DK1309581T3 (da) 2005-03-14
EP1309581B1 (en) 2004-11-03
AU2001100271A4 (en) 2001-09-13
JP2004506730A (ja) 2004-03-04
NZ523877A (en) 2004-08-27
DK200101219A (da) 2002-02-19
FR2813078B1 (fr) 2004-04-02
CN1339435A (zh) 2002-03-13
HK1047086A1 (en) 2003-02-07
CA2354877C (en) 2006-05-02
FI20011621A7 (fi) 2002-02-19
BG107584A (bg) 2004-01-30
AR029597A1 (es) 2003-07-10
GR20010100398A (el) 2002-05-24
EP1309582A1 (en) 2003-05-14
ES2170735B2 (es) 2003-09-16
FI20011621A0 (fi) 2001-08-09
SK287236B6 (sk) 2010-04-07
CZ294746B6 (cs) 2005-03-16
GB0119734D0 (en) 2001-10-03
FI20011621L (fi) 2002-02-19
SK3222003A3 (en) 2003-08-05

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