SG6889G - Devices for administering medicaments to patients - Google Patents

Devices for administering medicaments to patients

Info

Publication number
SG6889G
SG6889G SG68/89A SG6889A SG6889G SG 6889 G SG6889 G SG 6889G SG 68/89 A SG68/89 A SG 68/89A SG 6889 A SG6889 A SG 6889A SG 6889 G SG6889 G SG 6889G
Authority
SG
Singapore
Prior art keywords
patients
devices
administering medicaments
medicaments
administering
Prior art date
Application number
SG68/89A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838314307A external-priority patent/GB8314307D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SG6889G publication Critical patent/SG6889G/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M13/00—Insufflators for therapeutic or disinfectant purposes, i.e. devices for blowing a gas, powder or vapour into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6063—Optical identification systems
    • A61M2205/6081—Colour codes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
SG68/89A 1982-10-08 1989-02-09 Devices for administering medicaments to patients SG6889G (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8228887 1982-10-08
GB838314307A GB8314307D0 (en) 1983-05-24 1983-05-24 Medical administration devices

Publications (1)

Publication Number Publication Date
SG6889G true SG6889G (en) 1989-06-09

Family

ID=26284076

Family Applications (1)

Application Number Title Priority Date Filing Date
SG68/89A SG6889G (en) 1982-10-08 1989-02-09 Devices for administering medicaments to patients

Country Status (30)

Country Link
US (1) US4627432A (Direct)
JP (2) JPH05200100A (Direct)
KR (1) KR910002248B1 (Direct)
AT (1) AT396333B (Direct)
AU (2) AU570013B2 (Direct)
BR (1) BR8305562A (Direct)
CA (1) CA1224992A (Direct)
CH (1) CH662277A5 (Direct)
CY (2) CY1478A (Direct)
DE (1) DE3336486A1 (Direct)
DK (1) DK172541B1 (Direct)
ES (1) ES286422Y (Direct)
FI (1) FI79651C (Direct)
FR (2) FR2550452B1 (Direct)
GB (1) GB2129691B (Direct)
GR (1) GR79615B (Direct)
HK (1) HK67789A (Direct)
IE (1) IE56059B1 (Direct)
IL (1) IL69932A (Direct)
IN (1) IN160851B (Direct)
IT (1) IT1203660B (Direct)
KE (1) KE3860A (Direct)
LU (1) LU85034A1 (Direct)
NL (1) NL192564C (Direct)
NO (1) NO160330C (Direct)
NZ (1) NZ205892A (Direct)
PT (1) PT77471B (Direct)
SE (2) SE458824B (Direct)
SG (1) SG6889G (Direct)
ZW (1) ZW21483A1 (Direct)

Families Citing this family (399)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3348370C2 (de) * 1982-10-08 2001-10-11 Glaxo Group Ltd Medikamenten-Packung und Verfahren zur Erzeugung eines zur Inhalation bestimmten Medikamenten-Pulver-Luftstroms
SE448277B (sv) * 1985-04-12 1987-02-09 Draco Ab Indikeringsanordning vid en doseringsanordning for lekemedel
AU591152B2 (en) * 1985-07-30 1989-11-30 Glaxo Group Limited Devices for administering medicaments to patients
SE8605130L (sv) * 1986-07-24 1988-01-25 Marcus Diamant Redskap for utklemning av tabletter fran tablettkartor och liknande
US4817800A (en) * 1987-05-20 1989-04-04 Surgikos, Inc. Fluid injection system cassette and fluid packaging methods
FR2626500B1 (fr) * 1988-01-28 1990-04-27 Valois Sa Poussoir de vaporisateur agence pour operer le melange d'un additif dans l'emission du jet
CH678151A5 (en) * 1988-07-13 1991-08-15 Heinz Hermann Weick Self-medication nasal dispenser
US5239991A (en) * 1989-06-21 1993-08-31 Fisons Plc Disposable powder medicament inhalation device with peel-off cover
GB8914223D0 (en) * 1989-06-21 1989-08-09 Fisons Plc Medicament container
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5009561A (en) * 1989-08-18 1991-04-23 Pharmacia Diagnostics Inc. Reagent tablet dispenser
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
MY105368A (en) 1990-03-02 1994-09-30 Glaxo Group Ltd Inhalation device.
GB9012870D0 (en) * 1990-06-08 1990-08-01 Glaxo Group Ltd Device
DE4021263C2 (de) * 1990-07-04 1996-04-11 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
GB9021433D0 (en) * 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) * 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5042472A (en) * 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
NL9002706A (nl) * 1990-12-10 1992-07-01 Pharmachemie Bv Inrichting ten gebruike bij het inhaleren van in staafvormige capsules verpakte poedervormige stoffen.
GB2253200A (en) * 1991-02-01 1992-09-02 Harris Pharma Ltd Inhalation apparatus and fracturable capsule for use therewith
US5243970A (en) * 1991-04-15 1993-09-14 Schering Corporation Dosing device for administering metered amounts of powdered medicaments to patients
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) * 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
USD350602S (en) 1991-11-01 1994-09-13 Rhone-Poulenc Rorer Limited Combined dry powder inhaler and cap
DE4142238A1 (de) * 1991-12-20 1993-06-24 Boehringer Ingelheim Kg Pulverinhalator mit pulvertraeger aus regelmaessigen mikrostrukturen
GB2264237A (en) * 1992-02-05 1993-08-25 Robert Edward Newell An inhaler
GB9203761D0 (en) * 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
US5301664A (en) * 1992-03-06 1994-04-12 Sievers Robert E Methods and apparatus for drug delivery using supercritical solutions
US5394868A (en) * 1992-06-25 1995-03-07 Schering Corporation Inhalation device for powdered medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US5785049A (en) * 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
SK51695A3 (en) * 1992-10-19 1995-11-08 Dura Pharma Inc Dry powder medicament inhaler
US6250300B1 (en) 1992-12-11 2001-06-26 Ab Astra System for dispensing pharmaceutically active compounds
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US5368187A (en) * 1993-01-19 1994-11-29 Poncetta; Stanley Method and apparatus for dispensing materials from blister packages
US5743250A (en) * 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5970973A (en) * 1993-01-29 1999-10-26 Aradigm Corporation Method of delivering insulin lispro
US6024090A (en) 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US5873358A (en) * 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5819726A (en) * 1993-01-29 1998-10-13 Aradigm Corporation Method for the delivery of aerosolized drugs to the lung for the treatment of respiratory disease
US5724957A (en) * 1993-01-29 1998-03-10 Aradigm Corporation Intrapulmonary delivery of narcotics
US5934272A (en) * 1993-01-29 1999-08-10 Aradigm Corporation Device and method of creating aerosolized mist of respiratory drug
US7448375B2 (en) 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5558085A (en) * 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US6098620A (en) * 1993-01-29 2000-08-08 Aradigm Corporation Device for aerosolizing narcotics
US5915378A (en) * 1993-01-29 1999-06-29 Aradigm Corporation Creating an aerosolized formulation of insulin
US6131567A (en) * 1993-01-29 2000-10-17 Aradigm Corporation Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin
US5672581A (en) * 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
WO1994020164A1 (en) * 1993-03-03 1994-09-15 Glaxo Wellcome Inc. Dry powder inhalator medicament carrier
TW404844B (en) * 1993-04-08 2000-09-11 Oxford Biosciences Ltd Needleless syringe
US5372128A (en) * 1993-04-14 1994-12-13 Habley Medical Technology Corporation Fluidizing powder inhaler
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
USD358880S (en) 1993-12-02 1995-05-30 Tenax Corporation Dry powder inhalator
CZ295827B6 (cs) 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
US5664557A (en) * 1994-03-10 1997-09-09 Respiratory Delivery Systems, Inc. Releasably engageable coupling for an inhaler
US6102036A (en) * 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
GB9409851D0 (en) * 1994-05-17 1994-07-06 Cambridge Consultants Improvements in and relating to containers of particulate material
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
HU220472B1 (hu) * 1994-09-21 2002-02-28 Inhale Therapeutic Systems Eljárás és készülék por aeroszolosítására, valamint a készülékben alkalmazott adagolócső-egység
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
FR2725626A1 (fr) * 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
DE19502725B4 (de) * 1995-01-28 2004-03-04 Ing. Erich Pfeiffer Gmbh & Co Kg Austragvorrichtung für Medien
US5676643A (en) * 1995-02-13 1997-10-14 The Procter & Gamble Company Dispenser for friably releasing dry particulate medicaments
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5669973A (en) * 1995-06-06 1997-09-23 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing and retaining materials upon a substrate
US5714007A (en) 1995-06-06 1998-02-03 David Sarnoff Research Center, Inc. Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5642727A (en) * 1995-07-25 1997-07-01 David Sarnoff Research Center, Inc. Inhaler apparatus using a tribo-electric charging technique
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5692496A (en) * 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5988163A (en) * 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US6209538B1 (en) * 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
NL1001031C1 (nl) * 1995-08-23 1997-02-25 Npk Ind Design B V Inrichting voor het afgeven van pillen uit een blisterverpakking.
DK0865302T3 (da) 1995-12-07 2000-10-02 Jago Pharma Ag Inhalator til gentagen dosisvis afgivelse af farmakologisk tørpulver
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
US5823179A (en) 1996-02-13 1998-10-20 1263152 Ontario Inc. Nebulizer apparatus and method
USD395499S (en) 1996-04-08 1998-06-23 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5743251A (en) * 1996-05-15 1998-04-28 Philip Morris Incorporated Aerosol and a method and apparatus for generating an aerosol
US5871010A (en) * 1996-06-10 1999-02-16 Sarnoff Corporation Inhaler apparatus with modified surfaces for enhanced release of dry powders
US5857456A (en) * 1996-06-10 1999-01-12 Sarnoff Corporation Inhaler apparatus with an electronic means for enhanced release of dry powders
EP0951300A4 (en) 1996-12-31 2006-07-26 Nektar Therapeutics PROCESS FOR SPRAY DRYING OF SOLUTIONS OF HYDROPHILIC DRUGS WITH HYDROPHILIC BINDERS AND COMPOSITIONS MADE BY THIS METHOD
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5909822A (en) * 1997-05-03 1999-06-08 George; Donald C. Pill dispenser employing a sealed pill carrier
US5915560A (en) * 1997-05-03 1999-06-29 George; Donald C. Compartmentalized pill dispenser
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
EP1042025B1 (en) 1997-12-02 2009-06-03 Valois SAS Dry powder inhaler
USD412978S (en) 1997-12-02 1999-08-17 Dura Pharmaceuticals, Inc. Inhaler
CA2315777C (en) 1998-01-16 2008-12-23 1263152 Ontario Inc. Indicating device for use with a dispensing device
NZ506289A (en) 1998-03-16 2004-12-24 Nektar Therapeutics Aerosolized active agent delivery to the lungs at a flow rate of less than 17 liters per minute
US6729330B2 (en) 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US6336453B1 (en) 1999-04-30 2002-01-08 Trudell Medical International Indicating device for aerosol container
US6082358A (en) 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6149774A (en) 1998-06-10 2000-11-21 Delsys Pharmaceutical Corporation AC waveforms biasing for bead manipulating chucks
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
UA73924C2 (en) 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6234167B1 (en) 1998-10-14 2001-05-22 Chrysalis Technologies, Incorporated Aerosol generator and methods of making and using an aerosol generator
US6923979B2 (en) * 1999-04-27 2005-08-02 Microdose Technologies, Inc. Method for depositing particles onto a substrate using an alternating electric field
DE29908593U1 (de) 1999-05-14 1999-07-22 Jago Research AG, Hergiswil Mundstück für einen Inhalator zur Abgabe eines Medikaments
NZ515557A (en) 1999-06-05 2003-10-31 Innovata Biomed Ltd Delivery system
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US6730066B1 (en) * 1999-08-03 2004-05-04 Pharmacia Ab Liquid delivery container
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
US6810872B1 (en) * 1999-12-10 2004-11-02 Unisia Jecs Corporation Inhalant medicator
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
US6427688B1 (en) * 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
US7069929B2 (en) * 2000-02-01 2006-07-04 Quadrant Technologies Limited Dry powder inhaler
PL204106B1 (pl) 2000-02-28 2009-12-31 Pharmakodex Ltd Zestaw do dostarczania środka terapeutycznego
MY136453A (en) 2000-04-27 2008-10-31 Philip Morris Usa Inc "improved method and apparatus for generating an aerosol"
US6883516B2 (en) 2000-04-27 2005-04-26 Chrysalis Technologies Incorporated Method for generating an aerosol with a predetermined and/or substantially monodispersed particle size distribution
US6948494B1 (en) 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
GB0015034D0 (en) * 2000-06-21 2000-08-09 Glaxo Group Ltd Inhalation device
TWI224515B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd Pre-metered dose magazine for breath-actuated dry powder inhaler
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US6759398B2 (en) 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
CZ2003353A3 (cs) 2000-08-05 2003-05-14 Glaxo Group Limited Estery steroidních thiokyselin
US6948492B2 (en) * 2000-08-15 2005-09-27 University Of Kentucky Research Foundation Programmable multi-dose intranasal drug delivery device
US6491233B2 (en) 2000-12-22 2002-12-10 Chrysalis Technologies Incorporated Vapor driven aerosol generator and method of use thereof
US6701921B2 (en) 2000-12-22 2004-03-09 Chrysalis Technologies Incorporated Aerosol generator having heater in multilayered composite and method of use thereof
US6799572B2 (en) 2000-12-22 2004-10-05 Chrysalis Technologies Incorporated Disposable aerosol generator system and methods for administering the aerosol
US7077130B2 (en) 2000-12-22 2006-07-18 Chrysalis Technologies Incorporated Disposable inhaler system
US6681998B2 (en) 2000-12-22 2004-01-27 Chrysalis Technologies Incorporated Aerosol generator having inductive heater and method of use thereof
US6501052B2 (en) 2000-12-22 2002-12-31 Chrysalis Technologies Incorporated Aerosol generator having multiple heating zones and methods of use thereof
GB0103630D0 (en) 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
AU2002238801A1 (en) 2001-03-20 2002-10-03 Trudell Medical International Nebulizer apparatus and method
ES2296923T3 (es) 2001-03-22 2008-05-01 Glaxo Group Limited Derivados formanilidas como agonistas del adrenorreceptor beta2.
CN1302007C (zh) 2001-04-30 2007-02-28 葛兰素集团有限公司 具有抗炎性的在17.α位上具有环酯基的雄甾烷的17.β.－硫代羧酸酯衍生物
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US7176278B2 (en) 2001-08-30 2007-02-13 Biorexis Technology, Inc. Modified transferrin fusion proteins
CN103288793B (zh) 2001-09-14 2015-09-23 葛兰素集团有限公司 治疗呼吸疾病的苯乙醇胺衍生物
WO2003024396A2 (en) 2001-09-17 2003-03-27 Glaxo Group Limited Dry powder medicament formulations
US6871647B2 (en) 2001-09-19 2005-03-29 Advent Pharmaceuticals Pty Ltd Inhaler
US6640050B2 (en) 2001-09-21 2003-10-28 Chrysalis Technologies Incorporated Fluid vaporizing device having controlled temperature profile heater/capillary tube
US6568390B2 (en) 2001-09-21 2003-05-27 Chrysalis Technologies Incorporated Dual capillary fluid vaporizing device
US7931022B2 (en) * 2001-10-19 2011-04-26 Respirks, Inc. Method and apparatus for dispensing inhalator medicament
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US6804458B2 (en) * 2001-12-06 2004-10-12 Chrysalis Technologies Incorporated Aerosol generator having heater arranged to vaporize fluid in fluid passage between bonded layers of laminate
US6681769B2 (en) 2001-12-06 2004-01-27 Crysalis Technologies Incorporated Aerosol generator having a multiple path heater arrangement and method of use thereof
US6701922B2 (en) 2001-12-20 2004-03-09 Chrysalis Technologies Incorporated Mouthpiece entrainment airflow control for aerosol generators
US7458373B2 (en) 2002-01-15 2008-12-02 Philip Morris Usa Inc. Aerosol generator for drug formulation
GB0217199D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
WO2003074164A1 (en) * 2002-03-01 2003-09-12 Glaxo Group Limited Rotary blending apparatus and system
US7794965B2 (en) 2002-03-13 2010-09-14 Signum Biosciences, Inc. Method of identifying modulators of PP2A methylase
US7004164B2 (en) 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
AU2003225973A1 (en) * 2002-03-26 2003-11-11 Glaxo Group Limited A method for forming a laminate assembly and products formed thereby
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
DE10217929A1 (de) * 2002-04-22 2003-11-06 Sixp Ag Vorrichtung zur Ausgabe von Tabletten
JP2005524134A (ja) * 2002-04-25 2005-08-11 グラクソ　グループ　リミテッド 環境条件を検知するための磁気音響センサーシステムおよびそれに関連する方法
JP2005523920A (ja) 2002-04-25 2005-08-11 グラクソ　グループ　リミテッド フェネタノールアミン誘導体
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
GB2388040B (en) * 2002-05-02 2005-12-14 Robert Jeremy West Nicotine inhalation device
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
WO2003095005A1 (en) * 2002-05-10 2003-11-20 Chrysalis Technologies Incorporated Aerosol generator for drug formulation and methods of generating aerosol
AU2003269872A1 (en) * 2002-05-15 2003-12-31 Glaxo Group Limited Microelectromechanical system and method for determining temperature and moisture profiles within pharmaceutical packaging
US6904908B2 (en) 2002-05-21 2005-06-14 Trudell Medical International Visual indicator for an aerosol medication delivery apparatus and system
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
AU2003250166A1 (en) * 2002-07-25 2004-02-16 Glaxo Group Limited Medicament dispenser
EP1534368A1 (en) * 2002-07-25 2005-06-01 Glaxo Group Limited Medicament dispenser
GB0217198D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0217225D0 (en) 2002-07-25 2002-09-04 Glaxo Group Ltd Medicinal compounds
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
JP4387948B2 (ja) 2002-09-06 2009-12-24 フィリップ モーリス ユーエスエー インコーポレイテッド エアロゾルを発生させる方法
EP1565256A4 (en) * 2002-09-13 2008-05-07 Glaxo Group Ltd COATED MIXING DEVICE
US6772757B2 (en) 2002-10-25 2004-08-10 Chrysalis Technologies Incorporated Concentric controlled temperature profile fluid vaporizing device
CA2503588A1 (en) 2002-10-28 2004-05-06 Glaxo Group Limited Phenethanolamine derivative for the treatment of respiratory diseases
JP2006511297A (ja) * 2002-12-18 2006-04-06 グラクソ　グループ　リミテッド ベント型マウスピースを有する投薬システム
US20040173211A1 (en) * 2003-01-14 2004-09-09 Boehringer Ingelheim International Gmbh Powder inhaler
DE602004026406D1 (de) * 2003-02-05 2010-05-20 Martin John Tedham Spender für in einer blisterverpackung enthaltenen produckte
GB0303396D0 (en) 2003-02-14 2003-03-19 Glaxo Group Ltd Medicinal compounds
DE10317461A1 (de) 2003-04-16 2004-10-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Radioaktiv markierte Mikropartikel, Verfahren zu deren Herstellung und deren Verwendung
EP1488819A1 (en) * 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
GB0315509D0 (en) 2003-07-02 2003-08-06 Meridica Ltd Dispensing device
TW200519108A (en) 2003-07-17 2005-06-16 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
US7367334B2 (en) 2003-08-27 2008-05-06 Philip Morris Usa Inc. Fluid vaporizing device having controlled temperature profile heater/capillary tube
PL1677795T3 (pl) 2003-10-14 2011-05-31 Glaxo Group Ltd Antagoniści receptora muskarynowego acetylocholiny
MXPA06004242A (es) 2003-10-17 2006-06-28 Glaxo Group Ltd Antagonistas del receptor muscarinico de la acetilcolina.
US20070277820A1 (en) * 2003-10-27 2007-12-06 Timothy Crowder Blister packages and associated methods of fabricating dry powder drug containment systems
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
AR046225A1 (es) 2003-11-04 2005-11-30 Glaxo Group Ltd Compuesto de 8-azoniabiciclo(3.2.1)octano, composicion farmaceutica para el tratamiento de enfermedades mediadas por receptores de acetilcolina muscarinicos que lo comprende y uso del compuesto para preparar dicha composicion
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
WO2005053647A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
US7100530B2 (en) 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
GB0329182D0 (en) 2003-12-17 2004-01-21 Glaxo Group Ltd Chemical compounds
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
JP2007529513A (ja) 2004-03-17 2007-10-25 グラクソ　グループ　リミテッド Ｍ３ムスカリン性アセチルコリン受容体アンタゴニスト
BRPI0509382A (pt) 2004-04-02 2007-09-18 Glaxo Group Ltd processo para a preparação de um sal monocloridrato de composto, monocloridrato cristalino, processo para obter monocloridrato cristalino, método para a profilaxia ou o tratamento de uma condição clìnica em um mamìfero, uso de monocloridrato cristalino, formulação farmacêutica, e, combinação
EP1744800B1 (en) 2004-04-21 2016-06-22 Innovata Biomed Limited Inhaler
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
MY144753A (en) 2004-04-27 2011-10-31 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
WO2005112644A2 (en) 2004-05-13 2005-12-01 Glaxo Group Limited Muscarinic acetylcholine receptor antagonists
GB0418738D0 (en) * 2004-08-23 2004-09-22 3M Innovative Properties Co Medicinal aerosol formulation receptacle and production thereof
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
EA013776B1 (ru) * 2004-10-21 2010-06-30 Бёрингер Ингельхайм Интернациональ Гмбх Блистерная упаковка для применения в ингаляторах
WO2006047663A2 (en) * 2004-10-26 2006-05-04 The University Of North Carolina At Chapel Hill Aerosol generation of therapeutic agents
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
JP2008519984A (ja) * 2004-11-12 2008-06-12 グラクソ グループ リミテッド 音響変換器を備えるセンサシステム
MX2007008752A (es) 2005-01-20 2007-08-14 Trudell Medical Int Dispositivo surtidor.
US7923041B2 (en) 2005-02-03 2011-04-12 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
US8221804B2 (en) 2005-02-03 2012-07-17 Signum Biosciences, Inc. Compositions and methods for enhancing cognitive function
CN101155590A (zh) 2005-02-10 2008-04-02 葛兰素集团有限公司 使用预分选技术制备乳糖的方法以及由此形成的药物制剂
UY29439A1 (es) 2005-03-25 2006-10-02 Glaxo Group Ltd Nuevos compuestos
AR053346A1 (es) 2005-03-25 2007-05-02 Glaxo Group Ltd Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
US9585932B2 (en) 2005-04-29 2017-03-07 Peter C. Dowling Use of EPO-derived peptide fragments for the treatment of neurodegenerative disorders
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
WO2007052154A2 (en) * 2005-04-29 2007-05-10 University Of Medicine And Dentistry Of New Jersey Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
WO2006117353A1 (en) * 2005-05-04 2006-11-09 Boehringer Ingelheim International Gmbh Inhalation device containing plural doses of a pharmaceutical composition
DE102005035705A1 (de) * 2005-07-27 2007-02-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Arzneimittelblister
EP1937068A4 (en) 2005-08-18 2010-08-04 Glaxo Group Ltd ANTAGONISTS OF ACETYLCHOLINE MUSCARINIC RECEPTORS
US20090192227A1 (en) * 2005-08-24 2009-07-30 Rabindra Tirouvanziam N-Acetylcysteine Compositions and Methods for Treating Acute Exacerbations of Inflammatory Lung Disease
US20070049641A1 (en) * 2005-08-24 2007-03-01 Rabindra Tirouvanziam Methods for treating and monitoring inflammation and redox imbalance cystic fibrosis
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
US8227408B2 (en) * 2005-09-07 2012-07-24 Neurotez, Inc. Leptin as an anti-amyloidogenic biologic and methods for delaying the onset and reducing Alzheimer's disease-like pathology
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
EP1795221A1 (en) * 2005-12-02 2007-06-13 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
US8037880B2 (en) * 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
EP1844809A1 (de) * 2006-04-13 2007-10-17 Boehringer Ingelheim Pharma GmbH & Co. KG Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator
EP1844808A1 (de) * 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
US9457161B2 (en) 2006-05-18 2016-10-04 Boehringer Ingelheim International Gmbh Inhaler
DE102006043637A1 (de) * 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zerstäuber
DE102006023662A1 (de) * 2006-05-18 2007-11-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
WO2008024375A2 (en) 2006-08-21 2008-02-28 Trudell Medical International Respiratory muscle endurance training device and method for the use thereof
DE102006045788A1 (de) * 2006-09-26 2008-03-27 Alfred Von Schuckmann Spender für pulverförmige Massen
WO2008051621A2 (en) 2006-10-25 2008-05-02 Novartis Ag Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
GB0621957D0 (en) * 2006-11-03 2006-12-13 Vectura Group Plc Inhaler devices and bespoke pharmaceutical compositions
EP1925295A1 (de) 2006-11-22 2008-05-28 Boehringer Ingelheim Pharma GmbH & Co. KG Stabile Pulverformulierung enthaltend ein Anticholinergikum
US8377009B2 (en) 2007-01-09 2013-02-19 Mystic Pharmaceuticals, Inc. Intranasal cartridge devices
ES2624196T3 (es) * 2007-01-10 2017-07-13 Purdue Research Foundation Inhibidores polipéptidicos de HSP27 quinasa y usos de los mismos
AR065804A1 (es) 2007-03-23 2009-07-01 Smithkline Beecham Corp Compuesto de indol carboxamida, composicion farmaceutica que lo comprende y uso de dicho compuesto para preparar un medicamento
EP1992372A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992376A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992380A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992379A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992378A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992374A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992373A1 (en) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP1992377A1 (en) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
JP5328776B2 (ja) * 2007-06-01 2013-10-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 小出し器具
AT505246B8 (de) * 2007-06-01 2009-06-15 Croma Pharma Gmbh Container für eine mehrzahl von einzeldosen sowie applikator für derartige container
JP5703466B2 (ja) * 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ キナーゼ阻害薬およびその使用
EP2042208A1 (en) * 2007-09-25 2009-04-01 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device
EP2077132A1 (en) 2008-01-02 2009-07-08 Boehringer Ingelheim Pharma GmbH & Co. KG Dispensing device, storage device and method for dispensing a formulation
EP2082763A1 (en) * 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhaler
EP2254630A1 (de) * 2008-02-20 2010-12-01 Boehringer Ingelheim International GmbH Pulverinhalatoren
EP2259849A2 (en) * 2008-02-21 2010-12-15 Trudell Medical International Respiratory muscle endurance training device and method for the use thereof
US20090235929A1 (en) * 2008-03-19 2009-09-24 Marc Egen Powder inhalers
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
CA2725143A1 (en) * 2008-05-21 2009-11-26 Neurotez, Inc. Methods for treating progressive cognitive disorders related to neurofibrillary tangles
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
GB2463451A (en) 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
JP5470393B2 (ja) 2008-09-26 2014-04-16 オリエル・セラピューティクス，インコーポレイテッド ドライパウダー吸入器
MX2011003232A (es) * 2008-09-26 2011-04-21 Oriel Therapeutics Inc Mecanismos inhaladaores con perforadores radialmente desviados y métodos relacionados.
US8550071B2 (en) 2008-09-26 2013-10-08 Oriel Therapeutics, Inc. Inhalers with airway disks having discrete airway channels and related disks and methods
WO2010039201A2 (en) * 2008-09-30 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with multi-facet surface deagglomeration chambers and related devices and methods
US8646446B2 (en) * 2008-10-01 2014-02-11 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
RU2514318C2 (ru) * 2008-10-08 2014-04-27 Астразенека Аб Ингалятор со звуковыми индикаторными средствами
DK2349310T3 (da) * 2008-10-20 2014-08-11 Moerae Matrix Inc Polypeptid til behandling eller forebyggelse af adhæsioner
EP2179760B1 (en) 2008-10-22 2013-02-27 Trudell Medical International Modular Aerosol Delivery System
CN102300581B (zh) * 2008-11-04 2016-12-21 尼古拉斯·泰萨普塞蒂斯 用于治疗因神经原纤维缠结和β淀粉状蛋白的积聚引起的进行性认知功能障碍的瘦蛋白组合物和方法
EP2373366B1 (de) * 2008-12-03 2016-02-17 Boehringer Ingelheim International GmbH Inhalator
CA2744104C (en) * 2008-12-10 2017-07-18 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
GB0901520D0 (en) * 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
SI3578169T1 (sl) 2009-02-26 2024-09-30 Glaxo Group Limited Farmacevtske formulacije, ki obsegajo 4-((1R)-2-((6-(2-((2,6-dikloro- benzil)oksi)etoksi)heksil)amino)-1-hidroksietil)-2-(hidroksimetil)fenol
JP2012520701A (ja) 2009-03-17 2012-09-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 小出し器具、貯蔵器具及び調合薬を小出しする方法
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
NZ596564A (en) * 2009-05-21 2012-11-30 Microdose Therapeutx Inx Rotary cassette system for dry powder inhaler with blister packs, a vibrating element and a piercing element
WO2010147947A2 (en) 2009-06-16 2010-12-23 Schering Corporation NOVEL [3,2-c] HETEROARYL STEROIDS AS GLUCOCORTICOID RECEPTOR AGONISTS, COMPOSITIONS AND USES THEREOF
CN102762573B (zh) 2009-07-24 2015-09-16 阿马曾提斯公司 用于在神经退行性障碍中保护脑部健康的化合物、组合物和方法
WO2011017132A2 (en) * 2009-07-27 2011-02-10 Purdue Research, Foundation Mk2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
CA2784041C (en) 2010-01-05 2017-11-07 Microdose Therapeutx, Inc. Inhalation device and method
US8135497B2 (en) * 2010-01-13 2012-03-13 Joslyn Matthew I Portable, personal medication dispensing apparatus and method
CN102985044B (zh) 2010-03-18 2015-01-21 麦德康股份有限公司 用于打开医药泡罩包装的系统
USD635246S1 (en) 2010-03-26 2011-03-29 Oriel Therapeutics, Inc. Dose disk for dry powder inhalers
USD641076S1 (en) 2010-03-26 2011-07-05 Oriel Therapeutics, Inc. Dry powder inhaler
JP5792307B2 (ja) 2010-08-31 2015-10-07 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 水分制御特性を示す乾燥粉末吸入薬物製品及びその投与方法
EP2954888A1 (en) 2010-08-31 2015-12-16 GlaxoSmithKline Intellectual Property Development Limited Dry powder inhalation drug products exhibiting moisture control properties and methods of administering the same
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
US9297813B2 (en) 2010-11-11 2016-03-29 Agency For Science, Technology And Research Targeting metabolic enzymes in human cancer
DK2696888T3 (en) 2011-04-12 2019-03-25 Moerae Matrix Inc COMPOSITIONS AND METHODS FOR PREVENTION OR TREATMENT OF PULMONAL FIBROSE
US9890200B2 (en) 2011-04-12 2018-02-13 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
CA2981038C (en) 2011-05-19 2018-09-25 Savara Inc. Dry powder vancomycin compositions and associated methods
US8585659B2 (en) 2011-05-31 2013-11-19 Mystic Pharmaceuticals, Inc. Piercing device for drug delivery systems
GB201116641D0 (en) 2011-09-27 2011-11-09 Glaxo Group Ltd Novel compounds
EP2589381B1 (en) 2011-11-04 2016-08-31 Rabindra Tirouvanziam Compositions for improving or preserving lung function in a patient with a pulmonary disorder
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
JP6182594B2 (ja) 2012-04-27 2017-08-16 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 新規化合物
GB201207406D0 (en) 2012-04-27 2012-06-13 Glaxo Group Ltd Novel compounds
MX2015002842A (es) 2012-09-04 2015-08-12 Eleison Pharmaceuticals LLC Prevencion de la recurrencia pulmonar del cancer con cisplatino lipido-complejado.
EP2925328A1 (en) 2012-11-28 2015-10-07 Intercept Pharmaceuticals, Inc. Treatment of pulmonary disease
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
JP2015037466A (ja) * 2013-04-08 2015-02-26 ニップファーマ株式会社 薬剤吸入デバイス
CA2924062C (en) 2013-09-10 2019-05-14 Board Of Regents Of The University Of Texas System Therapeutics targeting truncated adenomatous polyposis coli (apc) proteins
JP6570189B2 (ja) 2013-10-15 2019-09-04 ミスティック ファーマシューティカルズ， インコーポレイテッド 制御可能な速度の乱流形成ノズル
US10336788B2 (en) 2014-04-17 2019-07-02 Moerae Matrix, Inc. Inhibition of cardiac fibrosis in myocardial infarction
AU2015250132B2 (en) 2014-04-24 2020-11-26 Questa Corporation Multi-size pill splitter and methods
MX2016014859A (es) 2014-05-12 2017-06-27 Glaxosmithkline Intellectual Property (No 2) Ltd Composiciones farmaceuticas que comprenden danirixina para tratar enfermedades infecciosas.
US10082496B2 (en) 2014-09-10 2018-09-25 Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
WO2016067252A1 (en) 2014-10-31 2016-05-06 Glaxosmithkline Intellectual Property Development Limited Powder formulation
WO2016081475A1 (en) 2014-11-17 2016-05-26 Moerae Matrix, Inc. Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
WO2016092378A1 (en) 2014-12-10 2016-06-16 Angelo Luigi Vescovi Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brian tumors
USD754919S1 (en) * 2014-12-19 2016-04-26 Fontem Holdings 4 B.V. Mouthpiece
KR20170102900A (ko) 2015-01-08 2017-09-12 모레 매트릭스 인코포레이티드 Mk2 저해제 펩타이드의 제형
AU2016209379A1 (en) 2015-01-21 2017-08-31 Mylan Inc. Medication packaging and dose regimen system
UY36578A (es) 2015-03-11 2016-09-30 Glaxosmithkline Ip Dev Ltd Proteínas de unión a tslp
AU2016229017A1 (en) 2015-03-12 2017-09-28 Moerae Matrix, Inc. Use of MK2 inhibitor peptide-containing compositions for treating non-small cell lung cancer with same
CN107847689A (zh) * 2015-05-22 2018-03-27 压孔普卡技术公司 用于压制片和松散填充植物源材料的气化器设备
WO2016200694A1 (en) 2015-06-10 2016-12-15 Hackensack University Medical Center Use of telmisartan to prevent and treat graft versus host disease and other alloimmune and autoimmune diseases
HUE052919T2 (hu) 2015-06-15 2021-05-28 Glaxosmithkline Ip Dev Ltd NRF2 szabályozók
JP2018517732A (ja) 2015-06-15 2018-07-05 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーター
CN108137557B (zh) 2015-06-15 2021-09-07 葛兰素史密斯克莱知识产权发展有限公司 Nrf2调节剂
WO2017007634A1 (en) 2015-07-06 2017-01-12 The Board Of Regents Of The University Of Texas System Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers
CA2991420A1 (en) 2015-07-15 2017-01-19 The Board Of Regents Of The University Of Texas System Targeting emopamil binding protein (ebp) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
JP2018529744A (ja) 2015-10-06 2018-10-11 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーターとしてのアリールシクロヘキシルピラゾール
WO2017060854A1 (en) 2015-10-06 2017-04-13 Glaxosmithkline Intellectual Property Development Limited Biaryl pyrazoles as nrf2 regulators
BR112018009899A8 (pt) 2015-11-18 2019-02-26 Glaxosmithkline Ip No 2 Ltd composição, inalador, forma de dosagem única, métodos para fabricar partículas, para melhorar as exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para prevenir as exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para reduzir a incidência das exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para reduzir a gravidade das exacerbações induzidas por infecção respiratória de um distúrbio respiratório, para prevenir uma infecção respiratória viral e para fabricar uma partícula de inalação de pó seco de ribavirina controlada na forma polimorfa cristalina, partículas fabricadas, método de tratamento, pluralidade de partículas, e, recipiente de dose.
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
CA3011185A1 (en) 2016-01-20 2017-07-27 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
ES2966349T3 (es) 2016-05-19 2024-04-22 Trudell Medical Int Cámara de retención con válvula inteligente
US10786638B2 (en) 2016-07-08 2020-09-29 Trudell Medical International Nebulizer apparatus and method
ES2988939T3 (es) 2016-07-08 2024-11-22 Trudell Medical Int Inc Dispositivo de presión espiratoria positiva oscilante inteligente
CN109790116B (zh) 2016-09-20 2022-10-28 葛兰素史密斯克莱知识产权（第2 号）有限公司 Trpv4拮抗剂
EP3515889A1 (en) 2016-09-20 2019-07-31 GlaxoSmithKline Intellectual Property (No. 2) Limited Trpv4 antagonists
TW201825458A (zh) 2016-09-20 2018-07-16 英商葛蘭素史克智慧財產（第二）有限公司 Ｔｒｐｖ４拮抗劑
KR20190088404A (ko) 2016-12-06 2019-07-26 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 3-(2,3-디히드로-1h-인덴-5-일)프로판산 유도체 및 nrf2 조절제로서의 그의 용도
WO2018104805A1 (en) 2016-12-09 2018-06-14 Trudell Medical International Smart nebulizer
US20200071310A1 (en) 2016-12-12 2020-03-05 Glaxosmithkline Intellectual Property Development Limited N-aryl pyrazoles as nrf2 regulators
JP2020500919A (ja) 2016-12-12 2020-01-16 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドＧｌａｘｏｓｍｉｔｈｋｌｉｎｅ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ Ｄｅｖｅｌｏｐｍｅｎｔ Ｌｉｍｉｔｅｄ Ｎｒｆ２レギュレーターとしての３−カルボン酸ピロール
EP3555068B1 (en) 2016-12-14 2020-12-02 GlaxoSmithKline Intellectual Property Development Limited 3-oxo-1,4-diazepinyle compounds as nrf2 activators
US11117905B2 (en) 2016-12-14 2021-09-14 Glaxosmithkline Intellectual Property Development Limited Bisaryl heterocycles as NRF2 activators
ES2901617T3 (es) 2016-12-14 2022-03-23 Glaxosmithkline Ip Dev Ltd Bisarilamidas como reguladores de NRF2
ES2908941T3 (es) 2016-12-15 2022-05-04 Glaxosmithkline Ip Dev Ltd Triazoles unidos a éter como reguladores de NRF2
BR112019012300A2 (pt) 2016-12-15 2019-11-12 Glaxosmithkline Intellectual Property Development Limited ativadores nrf2
CN108328122B (zh) * 2017-01-17 2024-04-12 李和伟 一种制剂盒
ES2901875T3 (es) 2017-04-24 2022-03-24 Cocrystal Pharma Inc Derivados de la pirrolopirimidina útiles como inhibidores de la replicación del virus de la influenza
EP3723764A1 (en) 2017-12-11 2020-10-21 GlaxoSmithKline Intellectual Property Development Ltd Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
WO2019116231A1 (en) 2017-12-11 2019-06-20 Glaxosmithkline Intellectual Property Development Limited Nrf2 activator for the treatment of acute lung injury, acute respiratory distress syndrome and multiple organ dysfunction syndrome
GB201720989D0 (en) 2017-12-15 2018-01-31 Glaxosmithkline Ip Dev Ltd Chemical compounds
JP7312754B2 (ja) 2018-01-04 2023-07-21 トゥルーデル メディカル インターナショナル スマート振動型呼気陽圧器具
CA3088347A1 (en) 2018-01-17 2019-07-25 Glaxosmithkline Intellectual Property Development Limited Pi4kiii.beta. inhibitors
CN108815653B (zh) * 2018-04-19 2020-11-10 山西白求恩医院 一种气体速度可调节的雾化器
US11643407B2 (en) 2018-05-23 2023-05-09 Glaxosmithkline Intellectual Property Development Limited Indanes as NRF2 activators
JP7522722B2 (ja) 2018-07-27 2024-07-25 コクリスタル ファーマ，インコーポレイテッド インフルエンザウイルス複製阻害剤としてのピロロ［２，３－ｂ］ピリジン誘導体
GB201812671D0 (en) 2018-08-03 2018-09-19 Coalesce Product Dev Ltd An inhaler device
JP7472108B2 (ja) 2018-09-10 2024-04-22 コクリスタル ファーマ，インコーポレイテッド ピリドピラジン系及びピリドトリアジン系インフルエンザウィルス複製阻害剤
CN112969457B (zh) 2018-10-17 2025-10-28 共晶制药公司 流感病毒复制抑制剂的组合
MX2021005582A (es) 2018-11-13 2021-06-30 Cocrystal Pharma Inc Formulaciones de terapias contra la gripe.
WO2020112716A1 (en) 2018-11-26 2020-06-04 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
WO2020135920A1 (en) * 2018-12-28 2020-07-02 Université Libre de Bruxelles Kit for inhaled chemotherapy, and treatment of lung cancer with said kit
DE102019134285A1 (de) 2019-01-15 2020-07-16 Nuuvera Deutschland GmbH Vorrichtung und Verfahren zum Extrahieren und Aspirieren von Wirkstoffen, insbesondere aus der Cannabispflanze
CN109939309B (zh) * 2019-04-01 2021-06-01 中国科学院大学深圳医院(光明) 粉状物吸入装置
GB201908536D0 (en) 2019-06-13 2019-07-31 Glaxosmithkline Ip Dev Ltd Compounds
WO2021038467A1 (en) 2019-08-27 2021-03-04 Trudell Medical International Smart oscillating positive expiratory pressure device
WO2021188620A1 (en) 2020-03-17 2021-09-23 Cocrystal Pharma Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
BR112022019557A2 (pt) 2020-04-10 2022-12-06 Cocrystal Pharma Inc Inibidores de replicação de norovírus e coronavírus
US20230158125A1 (en) 2020-04-20 2023-05-25 Sorrento Therapeutics, Inc. Pulmonary Administration of ACE2 Polypeptides
CN112298819A (zh) * 2020-10-28 2021-02-02 朱爱庆 一种具有防潮功能的定量取药瓶
WO2022175425A1 (en) 2021-02-22 2022-08-25 Glaxosmithkline Intellectual Property Development Limited Inhaled mtor kinase inhibitors for use in the treatment or the prevention of a respiratory rna virus infection
WO2022179967A1 (en) 2021-02-23 2022-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Vadadustat for treating covid-19 in a hospitalized subject
WO2022221530A1 (en) 2021-04-14 2022-10-20 The University Of North Carolina At Chapel Hill Hot porous-solid metering systems and methods for generation of therapeutic aerosols by evaporation/condensation
CA3227602A1 (en) 2021-08-03 2023-02-09 Irina C. Jacobson Inhibitors for coronaviruses
US11517704B1 (en) * 2021-12-06 2022-12-06 Stat Capsule Inc. Wristband capsule crusher
CN114098624B (zh) * 2021-12-30 2022-09-02 山东第一医科大学附属省立医院(山东省立医院) 一种可视的直肠快速内检装置

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB516834A (en) * 1937-12-23 1940-01-12 Charles Alexandre Nicolle Improvements in or relating to packaging
CH385718A (fr) * 1961-11-04 1964-12-15 Bodet Jean Procédé et dispositif pour conditionner des articles solides de petit volume, et ensemble obtenu par ce procédé
CH411232A (de) * 1963-11-12 1966-04-15 Ciba Geigy Arzneimittelverpackung
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
DE2321615A1 (de) * 1973-04-28 1974-11-14 Aluminium Walzwerke Singen Kindersichere verpackung
GB1387954A (en) * 1973-05-08 1975-03-19 Miles Lab Insufflator
US4015717A (en) * 1974-03-29 1977-04-05 The Medical Dispenser Company Tablet package for use in chronologically dispensing tablets
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
AT337088B (de) * 1975-05-20 1977-06-10 Desinfecta Ges M B H Verpackung fur pulver, korner und dgl. und verfahren zu ihrer herstellung
GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
DE2716323C2 (de) * 1977-04-07 1986-03-13 Schering AG, 1000 Berlin und 4709 Bergkamen Vorrichtung zur Inhalation von Arzneimitteln
DE2835122C3 (de) * 1978-08-10 1982-02-18 Bosch-Siemens Hausgeräte GmbH, 7000 Stuttgart Inhalationsgerät
GB2061735B (en) * 1979-10-30 1983-11-30 Riker Laboratories Inc Breath actuated device for administration of powdered medicaments by inhalation
CY1308A (en) * 1979-12-06 1985-12-06 Glaxo Group Ltd Device for dispensing medicaments
BR8007911A (pt) * 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
US4307734A (en) * 1980-06-23 1981-12-29 B & B Inventors & Marketers, Inc. Snuff dispenser
ES506585A0 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
DE8218231U1 (de) * 1982-06-25 1982-12-30 Karl Knauer Gmbh & Co Kg, 7616 Biberach Schaupackung insbesondere Blisterpackung

Also Published As

Publication number Publication date
DK464383A (da) 1984-04-09
NL8303461A (nl) 1984-05-01
JPH0620532Y2 (ja) 1994-06-01
FR2550452A1 (fr) 1985-02-15
CH662277A5 (de) 1987-09-30
IN160851B (Direct) 1987-08-08
GR79615B (Direct) 1984-10-31
DE3336486C2 (Direct) 1990-10-04
FI79651B (fi) 1989-10-31
NL192564C (nl) 1997-10-03
GB2129691A (en) 1984-05-23
IL69932A (en) 1987-12-31
FI833641A0 (fi) 1983-10-07
FR2570607B1 (fr) 1992-04-10
BR8305562A (pt) 1984-05-15
FI833641L (fi) 1984-04-09
AU584535B2 (en) 1989-05-25
NZ205892A (en) 1987-07-31
GB8326878D0 (en) 1983-11-09
SE8305542D0 (sv) 1983-10-07
NL192564B (nl) 1997-06-02
DK464383D0 (da) 1983-10-07
SE8803702L (sv) 1988-10-17
AT396333B (de) 1993-08-25
ES286422U (es) 1986-02-01
FR2550452B1 (fr) 1992-05-22
SE8305542L (sv) 1984-04-09
IT1203660B (it) 1989-02-15
NO160330C (no) 1989-04-12
CY1478A (en) 1989-07-21
DK172541B1 (da) 1998-12-07
KR910002248B1 (ko) 1991-04-08
NO833667L (no) 1984-04-09
SE458824B (sv) 1989-05-16
FR2570607A1 (fr) 1986-03-28
JPH05200100A (ja) 1993-08-10
JPH0576872B2 (Direct) 1993-10-25
HK67789A (en) 1989-09-01
ES286422Y (es) 1986-09-16
AU1997783A (en) 1984-04-12
KE3860A (en) 1989-06-02
ZW21483A1 (en) 1985-05-08
ATA357683A (de) 1992-12-15
US4627432A (en) 1986-12-09
JPH04131250U (ja) 1992-12-02
CY1477A (en) 1989-07-21
IL69932A0 (en) 1984-01-31
AU8315587A (en) 1988-04-21
PT77471A (en) 1983-11-01
KR840006441A (ko) 1984-11-30
IE56059B1 (en) 1991-04-10
NO160330B (no) 1989-01-02
SE8803702D0 (sv) 1988-10-17
CA1224992A (en) 1987-08-04
LU85034A1 (fr) 1985-06-19
DE3336486A1 (de) 1984-04-26
IE832367L (en) 1984-04-08
FI79651C (fi) 1990-02-12
GB2129691B (en) 1987-08-05
IT8349120A0 (it) 1983-10-07
PT77471B (en) 1986-08-19
SE465752B (sv) 1991-10-28
AU570013B2 (en) 1988-03-03

Similar Documents

Publication Publication Date Title
GB2129691B (en) Devices for administering medicaments to patients
GB8602264D0 (en) Administering medicaments to patients
GB2178965B (en) Devices for administering medicaments to patients
DE3166709D1 (en) Inhalation device for administering medicaments
ZA82124B (en) Bandage for administering beneficial drug
GB2184016B (en) Therapeutic device for the administration of medicaments
GB8327748D0 (en) Medicinal preparation
DE3372066D1 (en) Pharmaceutical preparation for endermic use
GB8418367D0 (en) Medicinal preparation
ZA81706B (en) Device for the administration of medicaments
ZA837318B (en) Device for administering medicaments to patients
DE3367734D1 (en) Apparatus for administering a liquid to patients
GB8403257D0 (en) Medicinal preparation
ZA865655B (en) Devices for administering medicaments to patients
ZA833721B (en) Administering fluid to patients
GB8525067D0 (en) Administering medicaments to patients
RO81783A3 (ro) Medicament pentru tratamentul maladiei neoplazice
KR850002630Y1 (en) Device for administering medicine orally
ZA812634B (en) Breath actuated devices for administering powered medicaments
GB8316632D0 (en) Administering medicaments
GB8315106D0 (en) Dose administering device