HK1246807A1 - Mk2抑制劑肽的製劑 - Google Patents
Mk2抑制劑肽的製劑Info
- Publication number
- HK1246807A1 HK1246807A1 HK18106201.2A HK18106201A HK1246807A1 HK 1246807 A1 HK1246807 A1 HK 1246807A1 HK 18106201 A HK18106201 A HK 18106201A HK 1246807 A1 HK1246807 A1 HK 1246807A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- formulation
- inhibitor peptides
- peptides
- inhibitor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562101190P | 2015-01-08 | 2015-01-08 | |
PCT/US2016/012650 WO2016112292A1 (en) | 2015-01-08 | 2016-01-08 | Formulation of mk2 inhibitor peptides |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1246807A1 true HK1246807A1 (zh) | 2018-09-14 |
Family
ID=56356475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18106201.2A HK1246807A1 (zh) | 2015-01-08 | 2018-05-14 | Mk2抑制劑肽的製劑 |
Country Status (14)
Country | Link |
---|---|
US (2) | US10087225B2 (zh) |
EP (1) | EP3242886A4 (zh) |
JP (1) | JP2018502860A (zh) |
KR (1) | KR20170102900A (zh) |
CN (1) | CN107406489A (zh) |
AU (1) | AU2016205125A1 (zh) |
BR (1) | BR112017014737A2 (zh) |
CA (1) | CA2972916A1 (zh) |
HK (1) | HK1246807A1 (zh) |
MX (1) | MX2017008994A (zh) |
RU (1) | RU2017128077A (zh) |
SG (1) | SG11201705559RA (zh) |
WO (1) | WO2016112292A1 (zh) |
ZA (1) | ZA201704495B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2874561T3 (es) | 2014-09-17 | 2021-11-05 | Celgene Car Llc | Inhibidores de MK2 y usos de los mismos |
EP3595658A4 (en) * | 2017-03-16 | 2020-11-25 | Celgene CAR LLC | FORMS AND COMPOSITIONS OF A MK2 INHIBITOR |
JP7216073B2 (ja) | 2018-03-13 | 2023-01-31 | 株式会社Adeka | 非水電解質二次電池 |
WO2021211854A1 (en) * | 2020-04-16 | 2021-10-21 | Cai Gu Huang | Inhalable formulation of a solution containing tiotropium bromide |
CN111647088B (zh) * | 2020-06-29 | 2023-05-02 | 东北师范大学 | 细胞渗透短肽tat-hns-3及对炎性疾病的应用 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1521000A (en) | 1975-06-13 | 1978-08-09 | Syntex Puerto Rico Inc | Inhalation device |
US4227522A (en) | 1978-09-05 | 1980-10-14 | Syntex Puerto Rico, Inc. | Inhalation device |
US4192309A (en) | 1978-09-05 | 1980-03-11 | Syntex Puerto Rico, Inc. | Inhalation device with capsule opener |
US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
CA1224992A (en) | 1982-10-08 | 1987-08-04 | Robert E. Newell | Device for administering medicament to patients |
FI88112C (fi) | 1985-07-30 | 1993-04-13 | Glaxo Group Ltd | Anordning foer administrering av laekemedel till patienter |
JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
WO2006050247A2 (en) * | 2004-10-29 | 2006-05-11 | Neose Technologies, Inc. | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
EP2155228B1 (en) | 2007-01-10 | 2014-04-02 | Purdue Research Foundation | Polypeptide inhibitors of hsp27 kinase and uses therefor |
ES2547229T3 (es) | 2007-08-07 | 2015-10-02 | Purdue Research Foundation | Inhibidores de cinasa y usos de los mismos |
CA2741302C (en) * | 2008-10-20 | 2017-02-28 | Moerae Matrix, Inc. | Mapkap kinase inhibitor polypeptide for treating or preventing adhesions |
EP2378875B1 (en) * | 2008-12-10 | 2018-05-30 | Purdue Research Foundation | Cell-permeant peptide-based inhibitor of kinases |
US9890195B2 (en) | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
EP2575855A4 (en) * | 2010-05-24 | 2014-03-12 | Moerae Matrix Inc | METHOD FOR TREATING OR PREVENTING VASCULAR GRAFT BREAKAGE |
US9890200B2 (en) * | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
AU2012242768B2 (en) * | 2011-04-12 | 2017-10-12 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
US20140072613A1 (en) * | 2012-09-10 | 2014-03-13 | Cynthia Lander | Compositions and Methods for Treating Cutaneous Scarring |
US9102015B2 (en) * | 2013-03-14 | 2015-08-11 | Siemens Energy, Inc | Method and apparatus for fabrication and repair of thermal barriers |
JP2016518358A (ja) * | 2013-04-11 | 2016-06-23 | ヴァンダービルト ユニバーシティーVanderbilt University | ポリプレックス |
-
2016
- 2016-01-08 US US14/991,531 patent/US10087225B2/en not_active Expired - Fee Related
- 2016-01-08 RU RU2017128077A patent/RU2017128077A/ru not_active Application Discontinuation
- 2016-01-08 CN CN201680005237.6A patent/CN107406489A/zh active Pending
- 2016-01-08 SG SG11201705559RA patent/SG11201705559RA/en unknown
- 2016-01-08 CA CA2972916A patent/CA2972916A1/en not_active Abandoned
- 2016-01-08 WO PCT/US2016/012650 patent/WO2016112292A1/en active Application Filing
- 2016-01-08 JP JP2017536526A patent/JP2018502860A/ja active Pending
- 2016-01-08 EP EP16735478.6A patent/EP3242886A4/en not_active Withdrawn
- 2016-01-08 AU AU2016205125A patent/AU2016205125A1/en not_active Abandoned
- 2016-01-08 MX MX2017008994A patent/MX2017008994A/es unknown
- 2016-01-08 KR KR1020177021042A patent/KR20170102900A/ko unknown
- 2016-01-08 BR BR112017014737A patent/BR112017014737A2/pt not_active Application Discontinuation
-
2017
- 2017-07-03 ZA ZA2017/04495A patent/ZA201704495B/en unknown
-
2018
- 2018-05-14 HK HK18106201.2A patent/HK1246807A1/zh unknown
- 2018-08-21 US US16/106,504 patent/US20190031730A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20160200782A1 (en) | 2016-07-14 |
US10087225B2 (en) | 2018-10-02 |
AU2016205125A1 (en) | 2017-07-13 |
RU2017128077A (ru) | 2019-02-08 |
RU2017128077A3 (zh) | 2019-09-30 |
JP2018502860A (ja) | 2018-02-01 |
BR112017014737A2 (pt) | 2018-01-16 |
SG11201705559RA (en) | 2017-08-30 |
ZA201704495B (en) | 2019-01-30 |
EP3242886A4 (en) | 2018-08-29 |
MX2017008994A (es) | 2018-09-18 |
US20190031730A1 (en) | 2019-01-31 |
KR20170102900A (ko) | 2017-09-12 |
AU2016205125A2 (en) | 2017-10-19 |
WO2016112292A1 (en) | 2016-07-14 |
EP3242886A1 (en) | 2017-11-15 |
CA2972916A1 (en) | 2016-07-14 |
CN107406489A (zh) | 2017-11-28 |
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