SG26346G - Therapeutic nucleosides - Google Patents

Therapeutic nucleosides

Info

Publication number
SG26346G
SG26346G SG1995903373A SG1995903373A SG26346G SG 26346 G SG26346 G SG 26346G SG 1995903373 A SG1995903373 A SG 1995903373A SG 1995903373 A SG1995903373 A SG 1995903373A SG 26346 G SG26346 G SG 26346G
Authority
SG
Singapore
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
Prior art date
Application number
SG1995903373A
Other languages
English (en)
Inventor
Thomas Anthony Krenitsky
Lilia Marie Beauchamp
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG26346(G) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719367A external-priority patent/GB8719367D0/en
Priority claimed from GB878725939A external-priority patent/GB8725939D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SG26346G publication Critical patent/SG26346G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
SG1995903373A 1987-08-15 1995-02-24 Therapeutic nucleosides SG26346G (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719367A GB8719367D0 (en) 1987-08-15 1987-08-15 Therapeutic compounds
GB878725939A GB8725939D0 (en) 1987-11-05 1987-11-05 Therapeutic compounds

Publications (1)

Publication Number Publication Date
SG26346G true SG26346G (en) 1995-09-01

Family

ID=26292613

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1995903373A SG26346G (en) 1987-08-15 1995-02-24 Therapeutic nucleosides

Country Status (30)

Country Link
EP (2) EP0596542B1 (hu)
JP (2) JPH0662623B2 (hu)
KR (2) KR960002849B1 (hu)
CN (1) CN1033701C (hu)
AP (2) AP160A (hu)
AT (1) ATE138660T1 (hu)
AU (1) AU612393C (hu)
CS (1) CS276903B6 (hu)
CY (1) CY1833A (hu)
DE (1) DE3855333T2 (hu)
DK (2) DK170045B1 (hu)
ES (1) ES2087639T3 (hu)
FI (1) FI89713C (hu)
GR (1) GR3020372T3 (hu)
HU (1) HU201071B (hu)
IE (1) IE65551B1 (hu)
IL (1) IL87434A (hu)
LU (1) LU88746I2 (hu)
LV (1) LV5264A3 (hu)
MC (1) MC1968A1 (hu)
MX (1) MX9203418A (hu)
MY (1) MY103760A (hu)
NL (1) NL960001I2 (hu)
NO (2) NO167805C (hu)
NZ (1) NZ225809A (hu)
PL (1) PL158285B1 (hu)
PT (1) PT88261B (hu)
SA (1) SA95160244B1 (hu)
SG (1) SG26346G (hu)
SU (1) SU1634138A3 (hu)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
AU618436B2 (en) * 1988-12-19 1991-12-19 Wellcome Foundation Limited, The Antiviral cytosine and guanine derivatives
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
ES2157259T3 (es) * 1993-06-10 2001-08-16 Rolabo Sl Procedimiento para preparar esteres de aminoacidos y analogos de nucleosidos.
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (hu) * 1993-11-18 1996-08-01 Ajinomoto Kk
DE69513313T2 (de) * 1994-02-01 2000-07-13 Ajinomoto Kk Verfahren zur Herstellung von Nukleinsäurebasenderivaten
US5840891A (en) * 1994-07-28 1998-11-24 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501142D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Compounds for use in medicine
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
DK0874631T3 (da) * 1996-01-19 2004-03-22 Glaxo Group Ltd Anvendelse af valaciclovir til fremstilling af et medikament til behandling af genital herpes ved en enkelt daglig anvendelse
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
ES2180923T5 (es) * 1996-01-26 2005-10-16 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de purina.
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
AU5495898A (en) * 1997-01-17 1998-08-07 Ajinomoto Co., Inc. Novel z-valacyclovir crystals
AU4007699A (en) * 1998-05-21 1999-12-06 Mark Anderson A method for stimulation of defensin production by exposure to isoleucin
SK1592004A3 (sk) * 2001-09-07 2005-03-04 Teva Pharmaceutical Industries Ltd. Kryštalické formy valaciklovírus hydrochlóridu
WO2004000265A2 (en) 2002-06-24 2003-12-31 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
CN1309732C (zh) * 2002-10-28 2007-04-11 南京长澳医药科技有限公司 6－烷氧基－2’，3’－双脱氧鸟嘌呤核苷的制备方法
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태
CN1331471C (zh) * 2003-09-22 2007-08-15 陈云芳 盐酸万乃洛韦软胶囊组合物
CA2552560A1 (en) * 2004-01-21 2005-08-11 Teva Pharmaceutical Industries Ltd. Process for the preparation of valacyclovir hydrochloride
GB2413017A (en) * 2004-04-06 2005-10-12 Ford Global Tech Llc An electrical connector for a vehicle
WO2006035452A1 (en) * 2004-09-27 2006-04-06 Matrix Laboratories Ltd Novel pseudomorph of valaciclovir hydrochloride
WO2006127217A2 (en) 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir
EP1746098A1 (en) 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
CN101456859B (zh) * 2009-01-06 2011-07-20 华南理工大学 抗病毒药物缬昔洛韦的制备方法
WO2011158252A1 (en) 2010-06-15 2011-12-22 Matrix Laboratories Ltd Process for the preparation of valacyclovir hydrochloride polymorphic form ii
CN102850354B (zh) * 2012-10-10 2014-07-23 山东金城医药化工股份有限公司 高纯度cbz-万乃洛韦的制备方法
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
RU2750867C1 (ru) * 2020-05-18 2021-07-05 Александр Сергеевич Самойлов Производные гуанина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3534774A1 (de) * 1985-09-30 1987-04-02 Robugen Gmbh Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
EP0308065A3 (en) 1989-09-27
KR890003761A (ko) 1989-04-17
CN1032538A (zh) 1989-04-26
DK451388D0 (da) 1988-08-12
CS8805594A2 (en) 1990-06-13
MC1968A1 (fr) 1989-09-29
PL158285B1 (en) 1992-08-31
CN1033701C (zh) 1997-01-01
ATE138660T1 (de) 1996-06-15
JPS6468373A (en) 1989-03-14
FI883757A0 (fi) 1988-08-12
EP0596542B1 (en) 1996-05-29
PT88261A (pt) 1989-06-30
CY1833A (en) 1995-12-01
SU1634138A3 (ru) 1991-03-07
AU2097888A (en) 1989-02-16
KR960002849B1 (ko) 1996-02-27
EP0308065A2 (en) 1989-03-22
DE3855333D1 (de) 1996-07-04
FI883757A (fi) 1989-02-16
NO883612D0 (no) 1988-08-12
NO1996015I1 (no) 1996-12-17
FI89713B (fi) 1993-07-30
CS276903B6 (en) 1992-09-16
DK451388A (da) 1989-02-16
DK82694A (da) 1994-07-08
IE882463L (en) 1989-02-15
IL87434A (en) 1993-06-10
AP160A (en) 1991-11-18
MX9203418A (es) 1992-07-01
ES2087639T3 (es) 1996-07-16
HUT47935A (en) 1989-04-28
EP0596542A1 (en) 1994-05-11
AU612393C (en) 2006-08-17
NO167805B (no) 1991-09-02
JPH07113025B2 (ja) 1995-12-06
IE65551B1 (en) 1995-11-01
DK170803B1 (da) 1996-01-22
IL87434A0 (en) 1989-01-31
GR3020372T3 (en) 1996-09-30
FI89713C (fi) 1993-11-10
AP8800099A0 (en) 1988-08-01
MY103760A (en) 1993-09-30
PL274215A1 (en) 1990-02-19
AU612393B2 (en) 1991-07-11
PT88261B (pt) 1995-03-01
NO167805C (no) 1991-12-11
NO883612L (no) 1989-02-16
LV5264A3 (lv) 1993-10-10
NL960001I1 (nl) 1996-03-01
DK170045B1 (da) 1995-05-08
SA95160244B1 (ar) 2006-10-02
AP55A (en) 1989-09-26
EP0308065B1 (en) 1995-01-04
JPH0662623B2 (ja) 1994-08-17
JPH03115284A (ja) 1991-05-16
NZ225809A (en) 1991-07-26
DE3855333T2 (de) 1996-12-05
NL960001I2 (nl) 1996-11-01
HU201071B (en) 1990-09-28
KR960004940B1 (ko) 1996-04-18
LU88746I2 (fr) 1996-10-04

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