FI883757A0 - Terapeutiska nukleosider. - Google Patents
Terapeutiska nukleosider.Info
- Publication number
- FI883757A0 FI883757A0 FI883757A FI883757A FI883757A0 FI 883757 A0 FI883757 A0 FI 883757A0 FI 883757 A FI883757 A FI 883757A FI 883757 A FI883757 A FI 883757A FI 883757 A0 FI883757 A0 FI 883757A0
- Authority
- FI
- Finland
- Prior art keywords
- nucleosider
- therapeutic
- therapeutic nucleosider
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878719367A GB8719367D0 (en) | 1987-08-15 | 1987-08-15 | Therapeutic compounds |
GB878725939A GB8725939D0 (en) | 1987-11-05 | 1987-11-05 | Therapeutic compounds |
GB8719367 | 1987-11-05 | ||
GB8725939 | 1987-11-05 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI883757A0 true FI883757A0 (fi) | 1988-08-12 |
FI883757A FI883757A (fi) | 1989-02-16 |
FI89713B FI89713B (fi) | 1993-07-30 |
FI89713C FI89713C (fi) | 1993-11-10 |
Family
ID=26292613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI883757A FI89713C (fi) | 1987-08-15 | 1988-08-12 | Foerfarande foer framstaellning av terapeutiskt aktivt 2-(2-amino-1,6-dihydro-6-oxo-9h(purin-9-yl)metoxi)etyl-l-valinat eller l-isoleucinat eller deras salt |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP0308065B1 (fi) |
JP (2) | JPH0662623B2 (fi) |
KR (2) | KR960002849B1 (fi) |
CN (1) | CN1033701C (fi) |
AP (2) | AP55A (fi) |
AT (1) | ATE138660T1 (fi) |
AU (1) | AU612393C (fi) |
CS (1) | CS276903B6 (fi) |
CY (1) | CY1833A (fi) |
DE (1) | DE3855333T2 (fi) |
DK (2) | DK170045B1 (fi) |
ES (1) | ES2087639T3 (fi) |
FI (1) | FI89713C (fi) |
GR (1) | GR3020372T3 (fi) |
HU (1) | HU201071B (fi) |
IE (1) | IE65551B1 (fi) |
IL (1) | IL87434A (fi) |
LU (1) | LU88746I2 (fi) |
LV (1) | LV5264A3 (fi) |
MC (1) | MC1968A1 (fi) |
MX (1) | MX9203418A (fi) |
MY (1) | MY103760A (fi) |
NL (1) | NL960001I2 (fi) |
NO (2) | NO167805C (fi) |
NZ (1) | NZ225809A (fi) |
PL (1) | PL158285B1 (fi) |
PT (1) | PT88261B (fi) |
SA (1) | SA95160244B1 (fi) |
SG (1) | SG26346G (fi) |
SU (1) | SU1634138A3 (fi) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AP55A (en) * | 1987-08-15 | 1989-09-26 | The Wellcome Foundation Ltd | Therapeutic Acyclic Nucleosides |
GB8816760D0 (en) * | 1988-07-14 | 1988-08-17 | Wellcome Found | Therapeutic compounds |
GB8829571D0 (en) * | 1988-12-19 | 1989-02-08 | Wellcome Found | Antiviral compounds |
JP2788084B2 (ja) * | 1988-12-19 | 1998-08-20 | ザ ウエルカム フアウンデーシヨン リミテツド | 抗ウイルス化合物 |
DE4008858A1 (de) * | 1990-03-20 | 1991-09-26 | Hoechst Ag | Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel |
US5831075A (en) * | 1993-06-10 | 1998-11-03 | Rolabo Sl | Amino acid ester of nucleoside analogues |
GB9317146D0 (en) * | 1993-08-18 | 1993-10-06 | Wellcome Found | Therapeutic combinations |
GB9320316D0 (en) * | 1993-10-01 | 1993-11-17 | Smithkline Beecham Plc | Pharmaceuticals |
TW282470B (fi) * | 1993-11-18 | 1996-08-01 | Ajinomoto Kk | |
EP0665229B1 (en) * | 1994-02-01 | 1999-11-17 | Ajinomoto Co., Inc. | Process for the production of nucleic acid base derivatives |
PE32296A1 (es) * | 1994-07-28 | 1996-08-07 | Hoffmann La Roche | Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables |
US5543414A (en) * | 1994-07-28 | 1996-08-06 | Syntex (Usa) Inc. | Achiral amino acid acyl esters of ganciclovir and its derivatives |
US5840891A (en) * | 1994-07-28 | 1998-11-24 | Syntex (U.S.A.) Inc. | 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
GB9501178D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Guanine derivative |
GB9501142D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Compounds for use in medicine |
GB9501127D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Tablet |
DE19536164A1 (de) * | 1995-09-28 | 1997-04-03 | Boehringer Ingelheim Kg | Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir) |
DK0874631T3 (da) * | 1996-01-19 | 2004-03-22 | Glaxo Group Ltd | Anvendelse af valaciclovir til fremstilling af et medikament til behandling af genital herpes ved en enkelt daglig anvendelse |
US5756736A (en) * | 1996-01-26 | 1998-05-26 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
US5840890A (en) * | 1996-01-26 | 1998-11-24 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
ATE222909T1 (de) * | 1996-01-26 | 2002-09-15 | Hoffmann La Roche | Verfahren zur herstellung von purin-derivaten |
US6040446A (en) | 1996-01-26 | 2000-03-21 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
US5700936A (en) * | 1996-01-26 | 1997-12-23 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate |
US5869493A (en) | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
IT1283447B1 (it) * | 1996-07-18 | 1998-04-21 | Ind Chimica Srl | Processo di preparazione del valaciclovir e relativi intermedi |
EP0976750A4 (en) * | 1997-01-17 | 2001-05-30 | Ajinomoto Kk | NEW Z-VALACYCLOVIR CRYSTALS |
CA2332961A1 (en) * | 1998-05-21 | 1999-11-25 | Michael Zasloff | A method for stimulation of defensin production by exposure to isoleucine |
US6849736B2 (en) * | 2001-09-07 | 2005-02-01 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of valacyclovir hydrochloride |
WO2004000265A2 (en) | 2002-06-24 | 2003-12-31 | Ranbaxy Laboratories Limited | Process for the preparation of robust formulations of valacyclovir hydrochloride tablets |
US20050043329A1 (en) * | 2002-09-06 | 2005-02-24 | Shlomit Wizel | Crystalline forms of valacyclovir hydrochloride |
CN1309732C (zh) * | 2002-10-28 | 2007-04-11 | 南京长澳医药科技有限公司 | 6-烷氧基-2’,3’-双脱氧鸟嘌呤核苷的制备方法 |
EP1638972A2 (en) * | 2003-06-02 | 2006-03-29 | Teva Pharmaceutical Industries Limited | Novel crystalline forms of valacyclovir hydrochloride |
CN1331471C (zh) * | 2003-09-22 | 2007-08-15 | 陈云芳 | 盐酸万乃洛韦软胶囊组合物 |
JP2007522130A (ja) * | 2004-01-21 | 2007-08-09 | テバ ファーマシューティカル インダストリーズ リミティド | 塩酸バラシクロビルの調製方法 |
GB2413017A (en) * | 2004-04-06 | 2005-10-12 | Ford Global Tech Llc | An electrical connector for a vehicle |
WO2006035452A1 (en) * | 2004-09-27 | 2006-04-06 | Matrix Laboratories Ltd | Novel pseudomorph of valaciclovir hydrochloride |
WO2006127217A2 (en) | 2005-05-25 | 2006-11-30 | Eli Lilly And Company | Cyclopropanecarboxylate esters of acyclovir |
EP1746098A1 (en) | 2005-07-21 | 2007-01-24 | SOLMAG S.p.A. | Valacyclovir polymorphs and a process for the preparation thereof |
CN101456859B (zh) * | 2009-01-06 | 2011-07-20 | 华南理工大学 | 抗病毒药物缬昔洛韦的制备方法 |
WO2011158252A1 (en) | 2010-06-15 | 2011-12-22 | Matrix Laboratories Ltd | Process for the preparation of valacyclovir hydrochloride polymorphic form ii |
CN102850354B (zh) * | 2012-10-10 | 2014-07-23 | 山东金城医药化工股份有限公司 | 高纯度cbz-万乃洛韦的制备方法 |
CN106632335A (zh) * | 2016-12-27 | 2017-05-10 | 河南康达制药有限公司 | 一种盐酸伐昔洛韦的制备方法 |
RU2750867C1 (ru) * | 2020-05-18 | 2021-07-05 | Александр Сергеевич Самойлов | Производные гуанина |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8202626A (nl) * | 1982-06-29 | 1984-01-16 | Stichting Rega V Z W | Derivaten van 9-(2-hydroxyethoxymethyl)guanine. |
DE3627024A1 (de) * | 1985-09-24 | 1987-04-02 | Hoechst Ag | In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine |
DE3534774A1 (de) * | 1985-09-30 | 1987-04-02 | Robugen Gmbh | Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung |
AP55A (en) * | 1987-08-15 | 1989-09-26 | The Wellcome Foundation Ltd | Therapeutic Acyclic Nucleosides |
-
1988
- 1988-08-10 AP APAP/P/1988/000099A patent/AP55A/en active
- 1988-08-10 AP APAP/P/1991/000238A patent/AP160A/en active
- 1988-08-11 MC MC881999A patent/MC1968A1/xx unknown
- 1988-08-12 EP EP88307512A patent/EP0308065B1/en not_active Expired - Lifetime
- 1988-08-12 NO NO883612A patent/NO167805C/no not_active IP Right Cessation
- 1988-08-12 ES ES93120604T patent/ES2087639T3/es not_active Expired - Lifetime
- 1988-08-12 KR KR1019880010298A patent/KR960002849B1/ko not_active IP Right Cessation
- 1988-08-12 HU HU884332A patent/HU201071B/hu unknown
- 1988-08-12 SU SU884356404A patent/SU1634138A3/ru active
- 1988-08-12 EP EP93120604A patent/EP0596542B1/en not_active Expired - Lifetime
- 1988-08-12 NZ NZ225809A patent/NZ225809A/en unknown
- 1988-08-12 CN CN88106535A patent/CN1033701C/zh not_active Expired - Lifetime
- 1988-08-12 LU LU88746C patent/LU88746I2/fr unknown
- 1988-08-12 IE IE246388A patent/IE65551B1/en not_active IP Right Cessation
- 1988-08-12 AT AT93120604T patent/ATE138660T1/de not_active IP Right Cessation
- 1988-08-12 AU AU20978/88A patent/AU612393C/en not_active Expired
- 1988-08-12 CS CS885594A patent/CS276903B6/cs not_active IP Right Cessation
- 1988-08-12 PL PL1988274215A patent/PL158285B1/pl unknown
- 1988-08-12 JP JP63200320A patent/JPH0662623B2/ja not_active Expired - Lifetime
- 1988-08-12 DK DK451388A patent/DK170045B1/da not_active IP Right Cessation
- 1988-08-12 PT PT88261A patent/PT88261B/pt not_active IP Right Cessation
- 1988-08-12 FI FI883757A patent/FI89713C/fi not_active IP Right Cessation
- 1988-08-12 MY MYPI88000934A patent/MY103760A/en unknown
- 1988-08-12 IL IL87434A patent/IL87434A/xx not_active IP Right Cessation
- 1988-08-12 DE DE3855333T patent/DE3855333T2/de not_active Expired - Lifetime
-
1990
- 1990-08-28 JP JP2226434A patent/JPH07113025B2/ja not_active Expired - Lifetime
-
1992
- 1992-06-25 MX MX9203418A patent/MX9203418A/es unknown
- 1992-12-18 LV LV920335A patent/LV5264A3/xx unknown
-
1994
- 1994-07-08 DK DK082694A patent/DK170803B1/da not_active IP Right Cessation
-
1995
- 1995-02-24 SG SG1995903373A patent/SG26346G/en unknown
- 1995-09-20 SA SA95160244A patent/SA95160244B1/ar unknown
- 1995-12-01 CY CY183395A patent/CY1833A/xx unknown
-
1996
- 1996-01-17 KR KR1019960000775A patent/KR960004940B1/ko not_active IP Right Cessation
- 1996-01-18 NL NL960001C patent/NL960001I2/nl unknown
- 1996-06-27 GR GR960401743T patent/GR3020372T3/el unknown
- 1996-12-17 NO NO1996015C patent/NO1996015I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI883757A0 (fi) | Terapeutiska nukleosider. | |
DE68921798D1 (de) | Therapeutische Nuleoside. | |
FI903656A0 (fi) | Terapeutiska kinuklidinfoereningar. | |
FI906367A0 (fi) | Terapeutiska nukleosider. | |
FI913899A0 (fi) | Terapeutiska aerosolblandningar. | |
DE3862564D1 (de) | Erdanker. | |
DE3873127D1 (de) | Therapeutische praeparate. | |
FI881651A0 (fi) | Terapeutiska nukleosider. | |
DE3884692D1 (de) | Defibrillator. | |
DE3785663D1 (de) | Loetgeraet. | |
FI904854A0 (fi) | Terapeutiska nukleosider. | |
FI902973A0 (fi) | Magnetfaeltsgenerator foer terapeutiska aendamaol. | |
FI875039A (fi) | Terapeutiska sammansaettningar foer veterinaermedicinsk anvaendning. | |
DE3788873D1 (de) | Massagegerät. | |
FI893897A0 (fi) | Terapeutiska nukleosider. | |
DE3885475D1 (de) | Eintaschverfahren. | |
DE3862309D1 (de) | Aminomethyltetrahydrofurane. | |
FI883441A (fi) | Hydrokanelsyraderivat. | |
FI881216A0 (fi) | Terapeutiska nukleosider. | |
DE3861694D1 (de) | Cyclopropancarboxamide. | |
FI894321A0 (fi) | Terapeutiska aemnen. | |
DE3860307D1 (de) | 2-aminomethyltetrahydrofurane. | |
DE3860710D1 (de) | Exklusiv-oder-schaltung. | |
DE3873615D1 (de) | Polycyanoarylthioether. | |
NO884021D0 (no) | Matlysthemmende tannpleiemiddel. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
ND | Supplementary protection certificate (spc) granted | ||
SPCG | Supplementary protection certificate granted |
Spc suppl protection certif: L52 Extension date: 20091220 |
|
FG | Patent granted |
Owner name: THE WELLCOME FOUNDATION LIMITED |
|
MA | Patent expired |