GR3020372T3 - Therapeutic nucleosides. - Google Patents

Therapeutic nucleosides.

Info

Publication number
GR3020372T3
GR3020372T3 GR960401743T GR960401743T GR3020372T3 GR 3020372 T3 GR3020372 T3 GR 3020372T3 GR 960401743 T GR960401743 T GR 960401743T GR 960401743 T GR960401743 T GR 960401743T GR 3020372 T3 GR3020372 T3 GR 3020372T3
Authority
GR
Greece
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
Prior art date
Application number
GR960401743T
Other languages
English (en)
Inventor
Thomas Anthony Krenitsky
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3020372(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719367A external-priority patent/GB8719367D0/en
Priority claimed from GB878725939A external-priority patent/GB8725939D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of GR3020372T3 publication Critical patent/GR3020372T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
GR960401743T 1987-08-15 1996-06-27 Therapeutic nucleosides. GR3020372T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB878719367A GB8719367D0 (en) 1987-08-15 1987-08-15 Therapeutic compounds
GB878725939A GB8725939D0 (en) 1987-11-05 1987-11-05 Therapeutic compounds
EP88307512A EP0308065B1 (en) 1987-08-15 1988-08-12 Therapeutic nucleosides

Publications (1)

Publication Number Publication Date
GR3020372T3 true GR3020372T3 (en) 1996-09-30

Family

ID=26292613

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960401743T GR3020372T3 (en) 1987-08-15 1996-06-27 Therapeutic nucleosides.

Country Status (30)

Country Link
EP (2) EP0596542B1 (el)
JP (2) JPH0662623B2 (el)
KR (2) KR960002849B1 (el)
CN (1) CN1033701C (el)
AP (2) AP160A (el)
AT (1) ATE138660T1 (el)
AU (1) AU612393C (el)
CS (1) CS276903B6 (el)
CY (1) CY1833A (el)
DE (1) DE3855333T2 (el)
DK (2) DK170045B1 (el)
ES (1) ES2087639T3 (el)
FI (1) FI89713C (el)
GR (1) GR3020372T3 (el)
HU (1) HU201071B (el)
IE (1) IE65551B1 (el)
IL (1) IL87434A (el)
LU (1) LU88746I2 (el)
LV (1) LV5264A3 (el)
MC (1) MC1968A1 (el)
MX (1) MX9203418A (el)
MY (1) MY103760A (el)
NL (1) NL960001I2 (el)
NO (2) NO167805C (el)
NZ (1) NZ225809A (el)
PL (1) PL158285B1 (el)
PT (1) PT88261B (el)
SA (1) SA95160244B1 (el)
SG (1) SG26346G (el)
SU (1) SU1634138A3 (el)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
DE68922903T2 (de) * 1988-12-19 1995-11-23 Wellcome Found Antivirale Pyrimidin- und Purinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
DE69426880T2 (de) * 1993-06-10 2001-10-31 Rolabo S.L., Zaragoza Verfahren zur herstellung von aminosäureester von nukleosid analogen
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (el) * 1993-11-18 1996-08-01 Ajinomoto Kk
EP0665229B1 (en) * 1994-02-01 1999-11-17 Ajinomoto Co., Inc. Process for the production of nucleic acid base derivatives
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
US5856481A (en) * 1994-07-28 1999-01-05 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
GB9501142D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Compounds for use in medicine
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
ES2210490T3 (es) * 1996-01-19 2004-07-01 Glaxo Group Limited Uso de valaciclovir para la fabricacion de un medicamento para el tratamiento del herpes genital por una unica administracion diaria.
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
ES2180923T5 (es) * 1996-01-26 2005-10-16 F. Hoffmann-La Roche Ag Proceso para la preparacion de derivados de purina.
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
EP0976750A4 (en) * 1997-01-17 2001-05-30 Ajinomoto Kk NEW Z-VALACYCLOVIR CRYSTALS
CA2332961A1 (en) * 1998-05-21 1999-11-25 Michael Zasloff A method for stimulation of defensin production by exposure to isoleucine
CA2457835A1 (en) * 2001-09-07 2003-03-20 Teva Pharmaceutical Industries Ltd. Crystalline forms of valacyclovir hydrochloride
AU2003240213A1 (en) 2002-06-24 2004-01-06 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
CN1309732C (zh) * 2002-10-28 2007-04-11 南京长澳医药科技有限公司 6－烷氧基－2’，3’－双脱氧鸟嘌呤核苷的制备方法
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태
CN1331471C (zh) * 2003-09-22 2007-08-15 陈云芳 盐酸万乃洛韦软胶囊组合物
JP2007522130A (ja) * 2004-01-21 2007-08-09 テバ ファーマシューティカル インダストリーズ リミティド 塩酸バラシクロビルの調製方法
GB2413017A (en) * 2004-04-06 2005-10-12 Ford Global Tech Llc An electrical connector for a vehicle
WO2006035452A1 (en) * 2004-09-27 2006-04-06 Matrix Laboratories Ltd Novel pseudomorph of valaciclovir hydrochloride
ATE546451T1 (de) 2005-05-25 2012-03-15 Lilly Co Eli Cyclopropancarbonsäureester von acyclovir
EP1746098A1 (en) 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
CN101456859B (zh) * 2009-01-06 2011-07-20 华南理工大学 抗病毒药物缬昔洛韦的制备方法
WO2011158252A1 (en) 2010-06-15 2011-12-22 Matrix Laboratories Ltd Process for the preparation of valacyclovir hydrochloride polymorphic form ii
CN102850354B (zh) * 2012-10-10 2014-07-23 山东金城医药化工股份有限公司 高纯度cbz-万乃洛韦的制备方法
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
RU2750867C1 (ru) * 2020-05-18 2021-07-05 Александр Сергеевич Самойлов Производные гуанина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3534774A1 (de) * 1985-09-30 1987-04-02 Robugen Gmbh Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
AP55A (en) 1989-09-26
AP160A (en) 1991-11-18
AU612393B2 (en) 1991-07-11
EP0596542A1 (en) 1994-05-11
IE882463L (en) 1989-02-15
IL87434A (en) 1993-06-10
AU2097888A (en) 1989-02-16
NO167805B (no) 1991-09-02
NO1996015I1 (no) 1996-12-17
NO883612L (no) 1989-02-16
MY103760A (en) 1993-09-30
NL960001I2 (nl) 1996-11-01
SG26346G (en) 1995-09-01
DK82694A (da) 1994-07-08
PL274215A1 (en) 1990-02-19
MX9203418A (es) 1992-07-01
FI89713C (fi) 1993-11-10
SU1634138A3 (ru) 1991-03-07
KR960004940B1 (ko) 1996-04-18
CS8805594A2 (en) 1990-06-13
ATE138660T1 (de) 1996-06-15
DE3855333D1 (de) 1996-07-04
AP8800099A0 (en) 1988-08-01
JPH0662623B2 (ja) 1994-08-17
DE3855333T2 (de) 1996-12-05
IL87434A0 (en) 1989-01-31
NO883612D0 (no) 1988-08-12
KR960002849B1 (ko) 1996-02-27
EP0308065B1 (en) 1995-01-04
NZ225809A (en) 1991-07-26
AU612393C (en) 2006-08-17
FI883757A0 (fi) 1988-08-12
LV5264A3 (lv) 1993-10-10
NL960001I1 (nl) 1996-03-01
ES2087639T3 (es) 1996-07-16
DK451388D0 (da) 1988-08-12
DK451388A (da) 1989-02-16
SA95160244B1 (ar) 2006-10-02
DK170045B1 (da) 1995-05-08
KR890003761A (ko) 1989-04-17
DK170803B1 (da) 1996-01-22
PT88261B (pt) 1995-03-01
FI89713B (fi) 1993-07-30
PL158285B1 (en) 1992-08-31
HU201071B (en) 1990-09-28
JPH03115284A (ja) 1991-05-16
JPS6468373A (en) 1989-03-14
EP0308065A3 (en) 1989-09-27
JPH07113025B2 (ja) 1995-12-06
HUT47935A (en) 1989-04-28
FI883757A (fi) 1989-02-16
CN1032538A (zh) 1989-04-26
LU88746I2 (fr) 1996-10-04
MC1968A1 (fr) 1989-09-29
PT88261A (pt) 1989-06-30
CY1833A (en) 1995-12-01
CN1033701C (zh) 1997-01-01
NO167805C (no) 1991-12-11
CS276903B6 (en) 1992-09-16
EP0596542B1 (en) 1996-05-29
IE65551B1 (en) 1995-11-01
EP0308065A2 (en) 1989-03-22

Similar Documents

Publication Publication Date Title
GR3020372T3 (en) Therapeutic nucleosides.
GR3015966T3 (en) Therapeutic nucleosides.
HK39595A (en) Therapeutic nucleosides
AP8800086A0 (en) Therapeutic nucleosides
EP0356166A3 (en) Therapeutic nucleosides
DE3872028D1 (en) Therapeutische nucleoside.
ZA881842B (en) Therapeutic nucleosides
ZA883830B (en) Therapeutic nucleosides
GB8823353D0 (en) Therapeutic nucleosides
GB8723013D0 (en) Therapeutic nucleosides
ZA882477B (en) Therapeutic nucleosides
PH29941A (en) Therapeutic nucleosides
GB8723793D0 (en) Therapeutic nucleosides
GB8723747D0 (en) Therapeutic nucleosides
GB8723746D0 (en) Therapeutic nucleosides
IE861273L (en) Therapeutic nucleosides
IE862454L (en) therapeutic nucleosides
IE870520L (en) Isohexide nucleoside
GB8816284D0 (en) Therapeutic nucleosides
IE880748L (en) Therapeutic nucleosides
IE881047L (en) Therapeutic nucleosides
GB8819732D0 (en) Therapeutic nucleosides
GB8824899D0 (en) Therapeutic nucleosides