IT1283447B1 - Processo di preparazione del valaciclovir e relativi intermedi - Google Patents

Processo di preparazione del valaciclovir e relativi intermedi

Info

Publication number
IT1283447B1
IT1283447B1 IT96MI001491A ITMI961491A IT1283447B1 IT 1283447 B1 IT1283447 B1 IT 1283447B1 IT 96MI001491 A IT96MI001491 A IT 96MI001491A IT MI961491 A ITMI961491 A IT MI961491A IT 1283447 B1 IT1283447 B1 IT 1283447B1
Authority
IT
Italy
Prior art keywords
valaciclovir
preparation process
related intermediates
intermediates
preparation
Prior art date
Application number
IT96MI001491A
Other languages
English (en)
Inventor
Maurizio Montoro
Silvio Pirovano
Original Assignee
Ind Chimica Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Chimica Srl filed Critical Ind Chimica Srl
Publication of ITMI961491A0 publication Critical patent/ITMI961491A0/it
Priority to IT96MI001491A priority Critical patent/IT1283447B1/it
Priority to ES97937496T priority patent/ES2212122T3/es
Priority to EP97937496A priority patent/EP0915874B1/en
Priority to AU40107/97A priority patent/AU4010797A/en
Priority to CA002261050A priority patent/CA2261050A1/en
Priority to PT97937496T priority patent/PT915874E/pt
Priority to PCT/EP1997/003826 priority patent/WO1998003553A1/en
Publication of ITMI961491A1 publication Critical patent/ITMI961491A1/it
Application granted granted Critical
Publication of IT1283447B1 publication Critical patent/IT1283447B1/it
Priority to BG103082A priority patent/BG63721B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
IT96MI001491A 1996-07-18 1996-07-18 Processo di preparazione del valaciclovir e relativi intermedi IT1283447B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT96MI001491A IT1283447B1 (it) 1996-07-18 1996-07-18 Processo di preparazione del valaciclovir e relativi intermedi
CA002261050A CA2261050A1 (en) 1996-07-18 1997-07-17 Process of preparation of valacyclovir and relevant intermediates
EP97937496A EP0915874B1 (en) 1996-07-18 1997-07-17 Process of preparation of valacyclovir and relevant intermediates
AU40107/97A AU4010797A (en) 1996-07-18 1997-07-17 Process of preparation of valacyclovir and relevant intermediates
ES97937496T ES2212122T3 (es) 1996-07-18 1997-07-17 Proceso de preparacion de valaciclovir y de productos intermedios adecuados.
PT97937496T PT915874E (pt) 1996-07-18 1997-07-17 Processo de preparacao de valaciclovir e intermediarios relevantes
PCT/EP1997/003826 WO1998003553A1 (en) 1996-07-18 1997-07-17 Process of preparation of valacyclovir and relevant intermediates
BG103082A BG63721B1 (bg) 1996-07-18 1999-01-14 Метод за получаване на валацикловир и релевантни междинни продукти

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96MI001491A IT1283447B1 (it) 1996-07-18 1996-07-18 Processo di preparazione del valaciclovir e relativi intermedi

Publications (3)

Publication Number Publication Date
ITMI961491A0 ITMI961491A0 (it) 1996-07-18
ITMI961491A1 ITMI961491A1 (it) 1998-01-18
IT1283447B1 true IT1283447B1 (it) 1998-04-21

Family

ID=11374611

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96MI001491A IT1283447B1 (it) 1996-07-18 1996-07-18 Processo di preparazione del valaciclovir e relativi intermedi

Country Status (8)

Country Link
EP (1) EP0915874B1 (it)
AU (1) AU4010797A (it)
BG (1) BG63721B1 (it)
CA (1) CA2261050A1 (it)
ES (1) ES2212122T3 (it)
IT (1) IT1283447B1 (it)
PT (1) PT915874E (it)
WO (1) WO1998003553A1 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849736B2 (en) * 2001-09-07 2005-02-01 Teva Pharmaceutical Industries Ltd. Crystalline forms of valacyclovir hydrochloride
KR20070020149A (ko) * 2001-11-14 2007-02-16 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르의 합성 및 정제 방법
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
AU2003232719A1 (en) * 2003-05-30 2005-01-21 Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. Novel crystalline forms of valacyclovir hydrochloride
EP1638972A2 (en) * 2003-06-02 2006-03-29 Teva Pharmaceutical Industries Limited Novel crystalline forms of valacyclovir hydrochloride
JP2007522130A (ja) * 2004-01-21 2007-08-09 テバ ファーマシューティカル インダストリーズ リミティド 塩酸バラシクロビルの調製方法
CN101068814A (zh) * 2004-09-04 2007-11-07 特瓦制药工业有限公司 分离的伐昔洛韦杂质，制备伐昔洛韦杂质的方法及其作为参比标准物的应用
US20060178512A1 (en) * 2005-02-04 2006-08-10 Cheruthur Govindan Method for preparing amino acid esters of nucleoside analogues
ES2291101B1 (es) * 2005-12-23 2009-02-16 Quimica Sintetica, S.A. Procedimiento para la preparacion de valaciclovir.
WO2008139539A1 (ja) * 2007-04-27 2008-11-20 Ajinomoto Co., Inc. バラシクロビルの製造方法
CN101456859B (zh) * 2009-01-06 2011-07-20 华南理工大学 抗病毒药物缬昔洛韦的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
US5831075A (en) * 1993-06-10 1998-11-03 Rolabo Sl Amino acid ester of nucleoside analogues
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative

Also Published As

Publication number Publication date
ES2212122T3 (es) 2004-07-16
EP0915874A2 (en) 1999-05-19
ITMI961491A1 (it) 1998-01-18
WO1998003553A1 (en) 1998-01-29
PT915874E (pt) 2004-04-30
EP0915874B1 (en) 2003-12-10
BG103082A (en) 1999-09-30
AU4010797A (en) 1998-02-10
ITMI961491A0 (it) 1996-07-18
CA2261050A1 (en) 1998-01-29
BG63721B1 (bg) 2002-10-31

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Legal Events

Date Code Title Description
0001 Granted