PT915874E - Processo de preparacao de valaciclovir e intermediarios relevantes - Google Patents
Processo de preparacao de valaciclovir e intermediarios relevantesInfo
- Publication number
- PT915874E PT915874E PT97937496T PT97937496T PT915874E PT 915874 E PT915874 E PT 915874E PT 97937496 T PT97937496 T PT 97937496T PT 97937496 T PT97937496 T PT 97937496T PT 915874 E PT915874 E PT 915874E
- Authority
- PT
- Portugal
- Prior art keywords
- valaciclovir
- intermediaries
- relevant
- preparation process
- preparation
- Prior art date
Links
- HDOVUKNUBWVHOX-QMMMGPOBSA-N Valacyclovir Chemical compound N1C(N)=NC(=O)C2=C1N(COCCOC(=O)[C@@H](N)C(C)C)C=N2 HDOVUKNUBWVHOX-QMMMGPOBSA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 229940093257 valacyclovir Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001491A IT1283447B1 (it) | 1996-07-18 | 1996-07-18 | Processo di preparazione del valaciclovir e relativi intermedi |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT915874E true PT915874E (pt) | 2004-04-30 |
Family
ID=11374611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97937496T PT915874E (pt) | 1996-07-18 | 1997-07-17 | Processo de preparacao de valaciclovir e intermediarios relevantes |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0915874B1 (pt) |
| AU (1) | AU4010797A (pt) |
| BG (1) | BG63721B1 (pt) |
| CA (1) | CA2261050A1 (pt) |
| ES (1) | ES2212122T3 (pt) |
| IT (1) | IT1283447B1 (pt) |
| PT (1) | PT915874E (pt) |
| WO (1) | WO1998003553A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1436295A4 (en) * | 2001-09-07 | 2007-07-11 | Teva Pharma | CRISTALLINE FORMS OF VALACYCLOVIR HYDROCHLORIDE |
| CA2649826A1 (en) * | 2001-11-14 | 2003-05-22 | Teva Pharmaceutical Industries Ltd. | Synthesis and purification of valacyclovir |
| US20050043329A1 (en) * | 2002-09-06 | 2005-02-24 | Shlomit Wizel | Crystalline forms of valacyclovir hydrochloride |
| AU2003232719A1 (en) * | 2003-05-30 | 2005-01-21 | Eos Eczacibasi Ozgun Kimyasal Urunler Sanayi Ve Ticaret A.S. | Novel crystalline forms of valacyclovir hydrochloride |
| EP2014660A3 (en) * | 2003-06-02 | 2009-07-15 | Teva Pharmaceutical Industries Ltd | Novel crystalline forms of valacyclovir hydrochloride |
| WO2005073233A1 (en) * | 2004-01-21 | 2005-08-11 | Teva Pharmaceutical Industries Ltd. | Process for the preparation of valacyclovir hydrochloride |
| CA2578750A1 (en) | 2004-09-04 | 2006-03-16 | Teva Pharmaceutical Industries, Ltd. | A valacyclovir impurity, process for the preparation of valacyclovir impurity and use as a reference standard |
| US20060178512A1 (en) * | 2005-02-04 | 2006-08-10 | Cheruthur Govindan | Method for preparing amino acid esters of nucleoside analogues |
| ES2291101B1 (es) * | 2005-12-23 | 2009-02-16 | Quimica Sintetica, S.A. | Procedimiento para la preparacion de valaciclovir. |
| WO2008139539A1 (ja) * | 2007-04-27 | 2008-11-20 | Ajinomoto Co., Inc. | バラシクロビルの製造方法 |
| CN101456859B (zh) * | 2009-01-06 | 2011-07-20 | 华南理工大学 | 抗病毒药物缬昔洛韦的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP160A (en) * | 1987-08-15 | 1991-11-18 | The Wellcome Foundation Ltd | Therapeutic acyclic nucleosides. |
| DE69426880T2 (de) * | 1993-06-10 | 2001-10-31 | Rolabo S.L., Zaragoza | Verfahren zur herstellung von aminosäureester von nukleosid analogen |
| GB9501178D0 (en) * | 1995-01-20 | 1995-03-08 | Wellcome Found | Guanine derivative |
-
1996
- 1996-07-18 IT IT96MI001491A patent/IT1283447B1/it active IP Right Grant
-
1997
- 1997-07-17 WO PCT/EP1997/003826 patent/WO1998003553A1/en active IP Right Grant
- 1997-07-17 CA CA002261050A patent/CA2261050A1/en not_active Abandoned
- 1997-07-17 ES ES97937496T patent/ES2212122T3/es not_active Expired - Lifetime
- 1997-07-17 EP EP97937496A patent/EP0915874B1/en not_active Expired - Lifetime
- 1997-07-17 PT PT97937496T patent/PT915874E/pt unknown
- 1997-07-17 AU AU40107/97A patent/AU4010797A/en not_active Abandoned
-
1999
- 1999-01-14 BG BG103082A patent/BG63721B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2261050A1 (en) | 1998-01-29 |
| AU4010797A (en) | 1998-02-10 |
| BG63721B1 (bg) | 2002-10-31 |
| ITMI961491A0 (pt) | 1996-07-18 |
| ITMI961491A1 (it) | 1998-01-18 |
| EP0915874A2 (en) | 1999-05-19 |
| EP0915874B1 (en) | 2003-12-10 |
| ES2212122T3 (es) | 2004-07-16 |
| IT1283447B1 (it) | 1998-04-21 |
| BG103082A (en) | 1999-09-30 |
| WO1998003553A1 (en) | 1998-01-29 |
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