NL960001I1 - Therapeutische nucleosiden. - Google Patents

Therapeutische nucleosiden.

Info

Publication number
NL960001I1
NL960001I1 NL960001C NL960001C NL960001I1 NL 960001 I1 NL960001 I1 NL 960001I1 NL 960001 C NL960001 C NL 960001C NL 960001 C NL960001 C NL 960001C NL 960001 I1 NL960001 I1 NL 960001I1
Authority
NL
Netherlands
Prior art keywords
therapeutic nucleosides
nucleosides
therapeutic
Prior art date
Application number
NL960001C
Other languages
English (en)
Other versions
NL960001I2 (nl
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL960001(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB878719367A external-priority patent/GB8719367D0/en
Priority claimed from GB878725939A external-priority patent/GB8725939D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NL960001I1 publication Critical patent/NL960001I1/nl
Publication of NL960001I2 publication Critical patent/NL960001I2/nl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
NL960001C 1987-08-15 1996-01-18 Therapeutische nucleosiden. NL960001I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878719367A GB8719367D0 (en) 1987-08-15 1987-08-15 Therapeutic compounds
GB878725939A GB8725939D0 (en) 1987-11-05 1987-11-05 Therapeutic compounds

Publications (2)

Publication Number Publication Date
NL960001I1 true NL960001I1 (nl) 1996-03-01
NL960001I2 NL960001I2 (nl) 1996-11-01

Family

ID=26292613

Family Applications (1)

Application Number Title Priority Date Filing Date
NL960001C NL960001I2 (nl) 1987-08-15 1996-01-18 Therapeutische nucleosiden.

Country Status (30)

Country Link
EP (2) EP0308065B1 (nl)
JP (2) JPH0662623B2 (nl)
KR (2) KR960002849B1 (nl)
CN (1) CN1033701C (nl)
AP (2) AP160A (nl)
AT (1) ATE138660T1 (nl)
AU (1) AU612393C (nl)
CS (1) CS276903B6 (nl)
CY (1) CY1833A (nl)
DE (1) DE3855333T2 (nl)
DK (2) DK170045B1 (nl)
ES (1) ES2087639T3 (nl)
FI (1) FI89713C (nl)
GR (1) GR3020372T3 (nl)
HU (1) HU201071B (nl)
IE (1) IE65551B1 (nl)
IL (1) IL87434A (nl)
LU (1) LU88746I2 (nl)
LV (1) LV5264A3 (nl)
MC (1) MC1968A1 (nl)
MX (1) MX9203418A (nl)
MY (1) MY103760A (nl)
NL (1) NL960001I2 (nl)
NO (2) NO167805C (nl)
NZ (1) NZ225809A (nl)
PL (1) PL158285B1 (nl)
PT (1) PT88261B (nl)
SA (1) SA95160244B1 (nl)
SG (1) SG26346G (nl)
SU (1) SU1634138A3 (nl)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.
GB8816760D0 (en) * 1988-07-14 1988-08-17 Wellcome Found Therapeutic compounds
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
DE68922903T2 (de) * 1988-12-19 1995-11-23 Wellcome Found Antivirale Pyrimidin- und Purinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
DE4008858A1 (de) * 1990-03-20 1991-09-26 Hoechst Ag Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
ES2157259T3 (es) * 1993-06-10 2001-08-16 Rolabo Sl Procedimiento para preparar esteres de aminoacidos y analogos de nucleosidos.
GB9317146D0 (en) * 1993-08-18 1993-10-06 Wellcome Found Therapeutic combinations
GB9320316D0 (en) * 1993-10-01 1993-11-17 Smithkline Beecham Plc Pharmaceuticals
TW282470B (nl) * 1993-11-18 1996-08-01 Ajinomoto Kk
EP0665229B1 (en) * 1994-02-01 1999-11-17 Ajinomoto Co., Inc. Process for the production of nucleic acid base derivatives
US5840891A (en) * 1994-07-28 1998-11-24 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) * 1994-07-28 1996-08-07 Hoffmann La Roche Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
GB9501178D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Guanine derivative
GB9501127D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Tablet
GB9501142D0 (en) * 1995-01-20 1995-03-08 Wellcome Found Compounds for use in medicine
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
CA2243237C (en) * 1996-01-19 2008-09-02 Glaxo Group Limited Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
JP4094667B2 (ja) * 1996-01-26 2008-06-04 エフ・ホフマン―ラ ロシュ アーゲー プリン誘導体の製造方法
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
IT1283447B1 (it) * 1996-07-18 1998-04-21 Ind Chimica Srl Processo di preparazione del valaciclovir e relativi intermedi
CN1250449A (zh) * 1997-01-17 2000-04-12 味之素株式会社 新型z－伐昔洛韦结晶
WO1999059574A1 (en) * 1998-05-21 1999-11-25 Magainin Pharmaceuticals, Inc. A method for stimulation of defensin production by exposure to isoleucin
EP1436295A4 (en) * 2001-09-07 2007-07-11 Teva Pharma CRISTALLINE FORMS OF VALACYCLOVIR HYDROCHLORIDE
AU2003240213A1 (en) 2002-06-24 2004-01-06 Ranbaxy Laboratories Limited Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) * 2002-09-06 2005-02-24 Shlomit Wizel Crystalline forms of valacyclovir hydrochloride
CN1309732C (zh) * 2002-10-28 2007-04-11 南京长澳医药科技有限公司 6－烷氧基－2’，3’－双脱氧鸟嘌呤核苷的制备方法
KR100871621B1 (ko) * 2003-06-02 2008-12-02 테바 파마슈티컬 인더스트리즈 리미티드 발라시클로비르 히드로클로라이드의 신규한 결정질 형태
CN1331471C (zh) * 2003-09-22 2007-08-15 陈云芳 盐酸万乃洛韦软胶囊组合物
JP2007522130A (ja) * 2004-01-21 2007-08-09 テバ ファーマシューティカル インダストリーズ リミティド 塩酸バラシクロビルの調製方法
GB2413017A (en) * 2004-04-06 2005-10-12 Ford Global Tech Llc An electrical connector for a vehicle
WO2006035452A1 (en) * 2004-09-27 2006-04-06 Matrix Laboratories Ltd Novel pseudomorph of valaciclovir hydrochloride
WO2006127217A2 (en) 2005-05-25 2006-11-30 Eli Lilly And Company Cyclopropanecarboxylate esters of acyclovir
EP1746098A1 (en) 2005-07-21 2007-01-24 SOLMAG S.p.A. Valacyclovir polymorphs and a process for the preparation thereof
CN101456859B (zh) * 2009-01-06 2011-07-20 华南理工大学 抗病毒药物缬昔洛韦的制备方法
WO2011158252A1 (en) 2010-06-15 2011-12-22 Matrix Laboratories Ltd Process for the preparation of valacyclovir hydrochloride polymorphic form ii
CN102850354B (zh) * 2012-10-10 2014-07-23 山东金城医药化工股份有限公司 高纯度cbz-万乃洛韦的制备方法
CN106632335A (zh) * 2016-12-27 2017-05-10 河南康达制药有限公司 一种盐酸伐昔洛韦的制备方法
RU2750867C1 (ru) * 2020-05-18 2021-07-05 Александр Сергеевич Самойлов Производные гуанина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3534774A1 (de) * 1985-09-30 1987-04-02 Robugen Gmbh Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
FI883757A0 (fi) 1988-08-12
CN1033701C (zh) 1997-01-01
FI883757A (fi) 1989-02-16
KR890003761A (ko) 1989-04-17
FI89713B (fi) 1993-07-30
CS8805594A2 (en) 1990-06-13
AU612393C (en) 2006-08-17
AP8800099A0 (en) 1988-08-01
CY1833A (en) 1995-12-01
DK451388A (da) 1989-02-16
GR3020372T3 (en) 1996-09-30
ATE138660T1 (de) 1996-06-15
DE3855333T2 (de) 1996-12-05
JPH03115284A (ja) 1991-05-16
AU612393B2 (en) 1991-07-11
DE3855333D1 (de) 1996-07-04
CS276903B6 (en) 1992-09-16
IE882463L (en) 1989-02-15
IL87434A (en) 1993-06-10
AP160A (en) 1991-11-18
NL960001I2 (nl) 1996-11-01
MC1968A1 (fr) 1989-09-29
PT88261A (pt) 1989-06-30
EP0596542B1 (en) 1996-05-29
EP0308065B1 (en) 1995-01-04
MX9203418A (es) 1992-07-01
NO883612L (no) 1989-02-16
DK451388D0 (da) 1988-08-12
SA95160244B1 (ar) 2006-10-02
IE65551B1 (en) 1995-11-01
KR960002849B1 (ko) 1996-02-27
CN1032538A (zh) 1989-04-26
PT88261B (pt) 1995-03-01
SG26346G (en) 1995-09-01
NO883612D0 (no) 1988-08-12
NO167805B (no) 1991-09-02
HU201071B (en) 1990-09-28
JPH0662623B2 (ja) 1994-08-17
AP55A (en) 1989-09-26
DK170045B1 (da) 1995-05-08
DK82694A (da) 1994-07-08
PL158285B1 (en) 1992-08-31
FI89713C (fi) 1993-11-10
DK170803B1 (da) 1996-01-22
IL87434A0 (en) 1989-01-31
LV5264A3 (lv) 1993-10-10
JPH07113025B2 (ja) 1995-12-06
EP0308065A3 (en) 1989-09-27
SU1634138A3 (ru) 1991-03-07
EP0596542A1 (en) 1994-05-11
JPS6468373A (en) 1989-03-14
HUT47935A (en) 1989-04-28
MY103760A (en) 1993-09-30
AU2097888A (en) 1989-02-16
NO1996015I1 (no) 1996-12-17
KR960004940B1 (ko) 1996-04-18
ES2087639T3 (es) 1996-07-16
LU88746I2 (fr) 1996-10-04
NZ225809A (en) 1991-07-26
EP0308065A2 (en) 1989-03-22
PL274215A1 (en) 1990-02-19
NO167805C (no) 1991-12-11

Similar Documents

Publication Publication Date Title
NL960001I1 (nl) Therapeutische nucleosiden.
ATE116648T1 (de) Therapeutische nucleoside.
MX9203215A (es) Nucleosidos terapeuticos.
ATE116984T1 (de) Therapeutische nukleoside.
DK564088D0 (da) Nukleosidderivater
FI902973A0 (fi) Magnetfaeltsgenerator foer terapeutiska aendamaol.
FI875039A0 (fi) Terapeutiska sammansaettningar foer veterinaermedicinsk anvaendning.
DE3788873T2 (de) Massagegerät.
MX9203420A (es) Nucleosidos terapeuticos.
DE3872028T2 (de) Therapeutische nucleoside.
ATE77386T1 (de) Therapeutische nucleoside.
DK725088A (da) Terapeutiske nucleosider
FI871028A (fi) Slirskydd med kombinationsstomme foer fordonsdaeck.
ATE104675T1 (de) Therapeutische nucleoside.
ES1003952Y (es) Pulsera terapeutica.
FI870144A0 (fi) Uppvaermningsanordning med staolplaotskonstruktion.
FI870526A0 (fi) Trevaegsventil med gummislang.
FI870853A0 (fi) Torkstaellning med flaekt.