SG173774A1 - Combination of a nucleoside polymerase inhibitor with a macrocyclic protease inhibitor and use thereof in the treatment of hepatitis c, liver fibrosis and impaired liver function - Google Patents
Combination of a nucleoside polymerase inhibitor with a macrocyclic protease inhibitor and use thereof in the treatment of hepatitis c, liver fibrosis and impaired liver function Download PDFInfo
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- SG173774A1 SG173774A1 SG2011059904A SG2011059904A SG173774A1 SG 173774 A1 SG173774 A1 SG 173774A1 SG 2011059904 A SG2011059904 A SG 2011059904A SG 2011059904 A SG2011059904 A SG 2011059904A SG 173774 A1 SG173774 A1 SG 173774A1
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Landscapes
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| NZ565059A (en) | 2005-07-25 | 2011-08-26 | Intermune Inc | Novel macrocyclic inhibitors of hepatitus C virus replication |
| BRPI0617274A2 (pt) * | 2005-10-11 | 2011-07-19 | Intermune Inc | compostos e métodos para a inibição de replicação viral de hepatite c |
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| CA2720729A1 (en) | 2008-04-15 | 2009-11-26 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
| AR075584A1 (es) | 2009-02-27 | 2011-04-20 | Intermune Inc | COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO. |
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| SG186830A1 (en) | 2010-07-22 | 2013-02-28 | Gilead Sciences Inc | Methods and compounds for treating paramyxoviridae virus infections |
| TW201300106A (zh) * | 2010-11-09 | 2013-01-01 | Hoffmann La Roche | 治療ｈｃｖ感染之醫藥組合物 |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| CH707030B1 (de) | 2011-10-21 | 2015-03-13 | Abbvie Inc | Kombinationsbehandlung von DAAs zur Verwendung in der Behandlung von HCV |
| ES2529143B1 (es) | 2011-10-21 | 2015-10-26 | Abbvie Inc. | Combinación de al menos dos agentes antivirales de acción directa, ribavirina pero no interferón para uso de tratamiento del vhc |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| CN104136453B (zh) | 2012-01-11 | 2018-01-12 | 艾伯维公司 | 用于制备hcv蛋白酶抑制剂的方法 |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| EA201590006A1 (ru) * | 2012-06-12 | 2015-05-29 | Ф. Хоффманн-Ля Рош Аг | Комбинация терапевтических средств для лечения инфекции, вызванной вирусом гепатита c |
| MX356551B (es) | 2012-08-23 | 2018-06-04 | Grupo Medifarma S A De C V Star | Composición antiséptica, antiseborreica y exfoliante para eliminar o prevenir el acné. |
| EP2897611B1 (en) * | 2012-09-18 | 2019-07-24 | AbbVie Inc. | Methods for treating hepatitis c |
| TWI687432B (zh) | 2014-10-29 | 2020-03-11 | 美商基利科學股份有限公司 | 絲狀病毒科病毒感染之治療 |
| CA3182565A1 (en) | 2015-03-06 | 2016-09-15 | Atea Pharmaceuticals, Inc. | .beta.-d-2'-deoxy-2'-.alpha.-fluoro-2'-.beta.-c-substituted-2-modified-n6-substituted purine nucleotides for hcv treatment |
| BR122020020217B1 (pt) | 2015-09-16 | 2021-08-17 | Gilead Sciences, Inc | Uso de um composto antiviral ou sal do mesmo para o tratamento de uma infecção por arenaviridae |
| EP3448392A4 (en) | 2016-04-28 | 2020-01-15 | Emory University | ALKYNOUS THERAPEUTIC NUCLEOTIDE AND NUCLEOSIDE COMPOSITIONS AND RELATED APPLICATIONS |
| LU100724B1 (en) | 2016-07-14 | 2018-07-31 | Atea Pharmaceuticals Inc | Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection |
| EP3865136A1 (en) | 2016-09-07 | 2021-08-18 | ATEA Pharmaceuticals, Inc. | 2'-substituted-n6-substituted purine nucleotides for corona virus treatment |
| CN106674224A (zh) * | 2016-12-20 | 2017-05-17 | 天津迈德新医药科技有限公司 | mPEG4‑阿巴卡韦及其制备方法和应用 |
| FI3577124T3 (fi) | 2017-02-01 | 2025-02-13 | Atea Pharmaceuticals Inc | Nukleotidihemisulfaattisuola hepatiitti C -viruksen hoitoon |
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| PL3651734T3 (pl) | 2017-07-11 | 2025-03-31 | Gilead Sciences, Inc. | Kompozycje zawierające inhibitor polimerazy rna i cyklodekstrynę do leczenia infekcji wirusowych |
| KR20200140865A (ko) | 2018-04-10 | 2020-12-16 | 아테아 파마슈티컬즈, 인크. | 간경변증을 갖는 hcv 감염 환자의 치료 |
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| TW202532084A (zh) | 2020-05-29 | 2025-08-16 | 美商基利科學股份有限公司 | 瑞德西韋之治療方法 |
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| PT4204421T (pt) | 2020-08-27 | 2024-06-25 | Gilead Sciences Inc | Compostos e métodos para o tratamento de infeções virais |
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| JP2025508942A (ja) | 2022-03-02 | 2025-04-10 | ギリアード サイエンシーズ， インコーポレイテッド | ウイルス感染症の治療のための化合物及び方法 |
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| AR075584A1 (es) | 2009-02-27 | 2011-04-20 | Intermune Inc | COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO. |
| WO2010118078A1 (en) | 2009-04-08 | 2010-10-14 | Idenix Pharmaceuticals, Inc. | Macrocyclic serine protease inhibitors |
| US8512690B2 (en) | 2009-04-10 | 2013-08-20 | Novartis Ag | Derivatised proline containing peptide compounds as protease inhibitors |
| HRP20181306T1 (hr) | 2009-04-25 | 2018-10-19 | F. Hoffmann - La Roche Ag | Metode za poboljšavanje farmakokinetike |
| TW201105323A (en) | 2009-06-23 | 2011-02-16 | Gilead Sciences Inc | Pharmaceutical compositions useful for treating HCV |
| US20100324059A1 (en) | 2009-06-23 | 2010-12-23 | Gilead Sciences, Inc. | Pharmaceutical compositions useful for treating hcv |
| UY32715A (es) | 2009-06-23 | 2011-01-31 | Gilead Sciences Inc | Combinaciones farmacéuticas útiles para el tratamiento del virus de la hepatitis c (vhc), usos y métodos relacionados |
| US8232246B2 (en) | 2009-06-30 | 2012-07-31 | Abbott Laboratories | Anti-viral compounds |
| KR20120110090A (ko) | 2009-09-28 | 2012-10-09 | 에프. 호프만-라 로슈 리미티드 | Ｃ형 간염 바이러스 복제의 신규한 마크로시클릭 저해제 |
-
2010
- 2010-02-23 AR ARP100100517A patent/AR075584A1/es unknown
- 2010-02-26 NZ NZ594524A patent/NZ594524A/xx not_active IP Right Cessation
- 2010-02-26 KR KR1020117021515A patent/KR20110135941A/ko not_active Ceased
- 2010-02-26 AU AU2010217818A patent/AU2010217818A1/en not_active Abandoned
- 2010-02-26 MA MA34087A patent/MA33236B1/fr unknown
- 2010-02-26 TW TW99105744A patent/TWI473810B/zh not_active IP Right Cessation
- 2010-02-26 PE PE2011001548A patent/PE20120777A1/es not_active Application Discontinuation
- 2010-02-26 JP JP2011552194A patent/JP2012519181A/ja active Pending
- 2010-02-26 BR BRPI1009338A patent/BRPI1009338A2/pt not_active IP Right Cessation
- 2010-02-26 US US12/713,497 patent/US8735345B2/en not_active Expired - Fee Related
- 2010-02-26 MX MX2011008980A patent/MX2011008980A/es active IP Right Grant
- 2010-02-26 RU RU2011139180/15A patent/RU2011139180A/ru unknown
- 2010-02-26 US US13/203,334 patent/US20120128628A1/en not_active Abandoned
- 2010-02-26 EP EP10706121A patent/EP2400966A1/en not_active Withdrawn
- 2010-02-26 WO PCT/US2010/025611 patent/WO2010099458A1/en not_active Ceased
- 2010-02-26 CN CN2010800099017A patent/CN102361641A/zh active Pending
- 2010-02-26 CA CA2751220A patent/CA2751220A1/en not_active Abandoned
- 2010-02-26 SG SG2011059904A patent/SG173774A1/en unknown
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2011
- 2011-08-21 IL IL214760A patent/IL214760A0/en unknown
- 2011-08-23 CR CR20110453A patent/CR20110453A/es not_active Application Discontinuation
- 2011-08-25 CO CO11108893A patent/CO6410304A2/es not_active Application Discontinuation
- 2011-08-26 CL CL2011002082A patent/CL2011002082A1/es unknown
- 2011-08-26 EC EC2011011292A patent/ECSP11011292A/es unknown
-
2015
- 2015-03-03 JP JP2015041648A patent/JP2015098501A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20100221217A1 (en) | 2010-09-02 |
| CL2011002082A1 (es) | 2012-04-13 |
| US20120128628A1 (en) | 2012-05-24 |
| JP2012519181A (ja) | 2012-08-23 |
| JP2015098501A (ja) | 2015-05-28 |
| KR20110135941A (ko) | 2011-12-20 |
| TWI473810B (zh) | 2015-02-21 |
| WO2010099458A1 (en) | 2010-09-02 |
| CN102361641A (zh) | 2012-02-22 |
| IL214760A0 (en) | 2011-11-30 |
| MA33236B1 (fr) | 2012-05-02 |
| AU2010217818A1 (en) | 2011-08-18 |
| NZ594524A (en) | 2013-09-27 |
| CA2751220A1 (en) | 2010-09-02 |
| EP2400966A1 (en) | 2012-01-04 |
| CO6410304A2 (es) | 2012-03-30 |
| ECSP11011292A (es) | 2011-12-30 |
| BRPI1009338A2 (pt) | 2016-11-01 |
| TW201035099A (en) | 2010-10-01 |
| MX2011008980A (es) | 2011-11-18 |
| PE20120777A1 (es) | 2012-06-27 |
| AR075584A1 (es) | 2011-04-20 |
| US8735345B2 (en) | 2014-05-27 |
| CR20110453A (es) | 2011-12-08 |
| RU2011139180A (ru) | 2013-04-10 |
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