SG144936A1 - 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative - Google Patents

7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative

Info

Publication number
SG144936A1
SG144936A1 SG200805397-7A SG2008053977A SG144936A1 SG 144936 A1 SG144936 A1 SG 144936A1 SG 2008053977 A SG2008053977 A SG 2008053977A SG 144936 A1 SG144936 A1 SG 144936A1
Authority
SG
Singapore
Prior art keywords
cyclopropylaminomethyl
pyrrolidinyl
substituted
acid derivative
quinolonecarboxylic acid
Prior art date
Application number
SG200805397-7A
Other languages
English (en)
Inventor
Asahina Yoshikazu
Masaya Takei
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Publication of SG144936A1 publication Critical patent/SG144936A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG200805397-7A 2003-09-10 2004-09-08 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative SG144936A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003318897 2003-09-10

Publications (1)

Publication Number Publication Date
SG144936A1 true SG144936A1 (en) 2008-08-28

Family

ID=34308537

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200805397-7A SG144936A1 (en) 2003-09-10 2004-09-08 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative

Country Status (18)

Country Link
US (2) US7514451B2 (fr)
EP (1) EP1666477B1 (fr)
JP (1) JP4639149B2 (fr)
KR (1) KR101077755B1 (fr)
CN (1) CN100410249C (fr)
AU (1) AU2004272414B2 (fr)
BR (1) BRPI0413964B8 (fr)
CA (1) CA2536429C (fr)
CY (1) CY1114476T1 (fr)
DK (1) DK1666477T3 (fr)
ES (1) ES2424676T3 (fr)
NO (1) NO333481B1 (fr)
NZ (1) NZ545472A (fr)
PL (1) PL1666477T3 (fr)
PT (1) PT1666477E (fr)
SG (1) SG144936A1 (fr)
SI (1) SI1666477T1 (fr)
WO (1) WO2005026147A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514451B2 (en) * 2003-09-10 2009-04-07 Kyorin Pharmaceutical Co., Ltd. 7-(4-Substituted-3-cyclopropylaminomethyl-1 pyrrolidinyl) quinolonecarboxylic acid derivative
JP5154402B2 (ja) * 2006-03-09 2013-02-27 杏林製薬株式会社 ３，４−ジ置換ピロリジン誘導体の製造方法及び製造中間体
BR112012030657A2 (pt) * 2010-05-31 2015-09-29 Kyorin Seiyaku Kk método para produzir derivado de 3-substituído-4-fluoropirrolidina
JP5844739B2 (ja) 2010-10-25 2016-01-20 杏林製薬株式会社 ３，４−二置換ピロリジン誘導体の製造方法
SA112330992B1 (ar) * 2011-11-10 2015-09-13 كيورين فارماسوتيكال كو.، ليمتد صورة متبلرة من 7-{(s4، s3)-3-[(سيكلو بروبيل أمينو) ميثيل]-4-فلورو بيروليدين-1-يل}-6-فلورو-1-(2-فلورو إيثيل)- 8-ميثوكسي-4-أوكسو-1، 4-داي هيدرو كينولين-3- حمض كربوكسيلي
WO2013145750A1 (fr) * 2012-03-29 2013-10-03 杏林製薬株式会社 Préparation pharmaceutique de capsule
JP6050322B2 (ja) * 2012-03-29 2016-12-21 杏林製薬株式会社 カプセル製剤
EP2990038B1 (fr) * 2013-04-25 2019-11-20 Kyorin Pharmaceutical Co., Ltd. Composition pharmaceutique solide
US9687453B2 (en) * 2013-04-25 2017-06-27 Kyorin Pharmaceutical Co., Ltd. Solid pharmaceutical composition
WO2014174848A1 (fr) * 2013-04-25 2014-10-30 杏林製薬株式会社 Comprimé
EP3210607A4 (fr) * 2014-10-23 2018-06-06 Kyorin Pharmaceutical Co., Ltd. Composition pharmaceutique solide
SG11201706951XA (en) * 2015-03-13 2017-09-28 Kyorin Seiyaku Kk Respiratory infection treating agent
JP6031217B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
US10406149B2 (en) 2015-06-02 2019-09-10 Kyorin Pharmaceutical Co., Ltd. Aqueous liquid formulation
EP3305295A4 (fr) * 2015-06-02 2019-02-20 Kyorin Pharmaceutical Co., Ltd. Médicament aqueux
JP6031216B1 (ja) * 2015-06-02 2016-11-24 杏林製薬株式会社 水性液剤
US10617684B2 (en) 2015-06-02 2020-04-14 Kyorin Pharmaceutical Co., Ltd. Aqueous drug
CN106831795B (zh) * 2017-01-16 2018-12-21 石家庄学院 喹诺酮异土木香内酯衍生物及其制备和应用
BR112019025960A2 (pt) 2017-06-16 2020-11-03 Kyorin Pharmaceutical Co., Ltd. agente terapêutico para pneumonia aspirativa, supuração pulmonar ou abcesso pulmonar
WO2018230686A1 (fr) 2017-06-16 2018-12-20 杏林製薬株式会社 Agent thérapeutique pour la pneumonie d'aspiration, la suppuration pulmonaire ou l'abcès pulmonaire

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Also Published As

Publication number Publication date
CA2536429A1 (fr) 2005-03-24
CA2536429C (fr) 2012-02-14
EP1666477A4 (fr) 2008-10-22
EP1666477A1 (fr) 2006-06-07
CN1849316A (zh) 2006-10-18
US20060281779A1 (en) 2006-12-14
KR101077755B1 (ko) 2011-10-27
BRPI0413964B1 (pt) 2017-03-28
NO333481B1 (no) 2013-06-24
PL1666477T3 (pl) 2013-11-29
WO2005026147A1 (fr) 2005-03-24
AU2004272414A1 (en) 2005-03-24
DK1666477T3 (da) 2013-07-29
PT1666477E (pt) 2013-08-28
BRPI0413964B8 (pt) 2021-05-25
KR20060123096A (ko) 2006-12-01
NO20061050L (no) 2006-04-04
US7514451B2 (en) 2009-04-07
CY1114476T1 (el) 2016-10-05
BRPI0413964A (pt) 2006-10-31
ES2424676T3 (es) 2013-10-07
CN100410249C (zh) 2008-08-13
SI1666477T1 (sl) 2013-10-30
US8106072B2 (en) 2012-01-31
AU2004272414B2 (en) 2009-05-28
NZ545472A (en) 2009-09-25
US20090176824A1 (en) 2009-07-09
JP4639149B2 (ja) 2011-02-23
JPWO2005026147A1 (ja) 2007-11-08
EP1666477B1 (fr) 2013-07-03

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