SG10201408229WA - Biomarkers and methods of treatment - Google Patents
Biomarkers and methods of treatmentInfo
- Publication number
- SG10201408229WA SG10201408229WA SG10201408229WA SG10201408229WA SG10201408229WA SG 10201408229W A SG10201408229W A SG 10201408229WA SG 10201408229W A SG10201408229W A SG 10201408229WA SG 10201408229W A SG10201408229W A SG 10201408229WA SG 10201408229W A SG10201408229W A SG 10201408229WA
- Authority
- SG
- Singapore
- Prior art keywords
- biomarkers
- treatment
- methods
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5752—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the lungs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q99/00—Subject matter not provided for in other groups of this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/4753—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Theoretical Computer Science (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Business, Economics & Management (AREA)
- General Business, Economics & Management (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37891110P | 2010-08-31 | 2010-08-31 | |
| US38992210P | 2010-10-05 | 2010-10-05 | |
| US39099510P | 2010-10-07 | 2010-10-07 | |
| US42070310P | 2010-12-07 | 2010-12-07 | |
| US201161487527P | 2011-05-18 | 2011-05-18 | |
| US201161492338P | 2011-06-01 | 2011-06-01 | |
| US201161503489P | 2011-06-30 | 2011-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201408229WA true SG10201408229WA (en) | 2015-02-27 |
Family
ID=44583514
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201408229WA SG10201408229WA (en) | 2010-08-31 | 2011-08-31 | Biomarkers and methods of treatment |
| SG2013011911A SG187886A1 (en) | 2010-08-31 | 2011-08-31 | Biomarkers and methods of treatment |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013011911A SG187886A1 (en) | 2010-08-31 | 2011-08-31 | Biomarkers and methods of treatment |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20120089541A1 (https=) |
| EP (2) | EP2612151B1 (https=) |
| JP (2) | JP2013537966A (https=) |
| KR (1) | KR20130103734A (https=) |
| CN (1) | CN103221825A (https=) |
| AU (1) | AU2011295919A1 (https=) |
| BR (1) | BR112013004673A8 (https=) |
| CA (1) | CA2808236A1 (https=) |
| DK (1) | DK2612151T3 (https=) |
| ES (1) | ES2641916T3 (https=) |
| IL (1) | IL248530A0 (https=) |
| MX (1) | MX2013002084A (https=) |
| RU (1) | RU2013114360A (https=) |
| SG (2) | SG10201408229WA (https=) |
| WO (1) | WO2012031027A1 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100135780A (ko) * | 2008-03-06 | 2010-12-27 | 제넨테크, 인크. | C-met 및 egfr 길항제로의 조합 요법 |
| EP2496601B1 (en) | 2009-11-05 | 2017-06-07 | F. Hoffmann-La Roche AG | Methods and composition for secretion of heterologous polypeptides |
| AR086823A1 (es) * | 2011-06-30 | 2014-01-22 | Genentech Inc | Formulaciones de anticuerpo anti-c-met, metodos |
| SG11201400724SA (en) | 2011-09-19 | 2014-04-28 | Genentech Inc | Combination treatments comprising c-met antagonists and b-raf antagonists |
| EP2758057B1 (en) * | 2011-09-22 | 2017-05-31 | Exelixis, Inc. | Method for treating osteoporosis |
| WO2013166296A1 (en) | 2012-05-02 | 2013-11-07 | Exelixis, Inc. | A dual met - vegf modulator for treating osteolytic bone metastases |
| KR101938699B1 (ko) * | 2012-07-23 | 2019-01-16 | 삼성전자주식회사 | Lrig1의 항 c―met 항체 적용 대상 환자 선별을 위한 용도 |
| KR101938698B1 (ko) | 2012-07-23 | 2019-01-16 | 삼성전자주식회사 | Cbl의 항 c-met 항체 적용 대상 환자 선별을 위한 바이오마커로서의 용도 |
| US20140030259A1 (en) * | 2012-07-27 | 2014-01-30 | Genentech, Inc. | Methods of treating fgfr3 related conditions |
| US9446039B2 (en) * | 2012-08-27 | 2016-09-20 | Cemm Forschungszentrum Für Molekulare Medizin Gmbh | Aminoheteroaryl compounds as MTH1 inhibitors |
| US20150276748A1 (en) * | 2012-10-25 | 2015-10-01 | Cedars-Sinai Medical Center | Methods of prognosticating and treating cancer |
| KR20140093347A (ko) * | 2013-01-15 | 2014-07-28 | 삼성전자주식회사 | 항 c-Met 항체 처리에 의해 부작용을 유발하는 유전자 및 이를 이용한 약물 스크리닝 방법 |
| JP6352952B2 (ja) | 2013-03-07 | 2018-07-04 | バーマーサ・リサーチ・エルエルシーBarmarsa Research Llc | グリアジンペプチドを用いた癌の治療のためのキットおよび方法 |
| US10933417B2 (en) | 2013-03-15 | 2021-03-02 | Nanobiosym, Inc. | Systems and methods for mobile device analysis of nucleic acids and proteins |
| HK1218096A1 (zh) * | 2013-03-15 | 2017-02-03 | Nanobiosym, Inc. | 用於移动设备分析核酸和蛋白质的系统和方法 |
| WO2014150819A2 (en) * | 2013-03-15 | 2014-09-25 | Genentech, Inc. | Biomarkers and methods of treatment |
| BR112015023120A2 (pt) * | 2013-03-15 | 2017-11-21 | Genentech Inc | método para identificar um indivíduo com uma doença ou disfunção, método para prever a responsividade de um indivíduo com uma doença ou disfunção, método para determinar a probabilidade de que um indivíduo com uma doença ou disfunção exibirá benefício do tratamento, método para selecionar uma terapia, usos de um antagonista de ligação do eixo pd-l1, ensaio para identificar um indivíduo com uma doença, kit de diagnóstico, método para avaliar uma resposta ao tratamento e método para monitorar a resposta de um indivíduo tratado |
| WO2015010596A1 (zh) * | 2013-07-22 | 2015-01-29 | 北京盛诺基医药科技有限公司 | 一种乳腺癌预后诊断的方法 |
| WO2015031626A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Soluble cmet assay |
| WO2015031614A1 (en) * | 2013-08-28 | 2015-03-05 | Abbvie Inc. | Soluble cmet assay |
| WO2015069489A1 (en) | 2013-11-06 | 2015-05-14 | Merck Patent Gmbh | Predictive biomarker for hypoxia-activated prodrug therapy |
| KR102272788B1 (ko) * | 2014-01-07 | 2021-07-05 | 삼성전자주식회사 | c-Met 저해제의 효능 예측 또는 효능 검증을 위한 바이오마커 |
| EP2891884B1 (en) | 2014-01-07 | 2017-10-25 | Samsung Electronics Co., Ltd | IL-8 for predicting or monitoring efficacy of c-MET inhibitor |
| AU2015229035B2 (en) | 2014-03-14 | 2021-08-05 | Genentech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| RU2016141385A (ru) * | 2014-03-24 | 2018-04-28 | Дженентек, Инк. | Лечение рака антагонистами с-мет и их корреляция с экспрессией hgf |
| US20160327559A1 (en) * | 2014-04-24 | 2016-11-10 | Fundació Institut Mar D'investigacions Mèdiques (Imim) | Hepatocyte growth factor as marker of prognosis in small cell lung cancer (sclc) |
| CN107517590B (zh) * | 2014-07-29 | 2021-11-12 | 威马克生物有限公司 | 与表皮生长因子受体-靶制剂有关的感受性预测用新型生物标志物及其用途 |
| KR20160024639A (ko) | 2014-08-26 | 2016-03-07 | 삼성전자주식회사 | c-Met 표적 치료제의 저항성 또는 효능 예측을 위한 바이오마커 PDGF |
| JP2016155776A (ja) * | 2015-02-24 | 2016-09-01 | 学校法人兵庫医科大学 | 抗腫瘍効果増強剤および抗腫瘍剤 |
| RU2714233C2 (ru) | 2015-02-26 | 2020-02-13 | Мерк Патент Гмбх | Ингибиторы pd-1 / pd-l1 для лечения рака |
| MY193229A (en) | 2015-06-16 | 2022-09-26 | Merck Patent GmbH | Pd-l1 antagonist combination treatments |
| CN105087775A (zh) * | 2015-07-24 | 2015-11-25 | 北京莱尔生物医药科技有限公司 | 一种基于稀有细胞检测c-MET/CEP7基因状态的方法及相关试剂盒 |
| CA2999895A1 (en) | 2015-09-24 | 2017-03-30 | Expression Pathology, Inc. | Quantifying met protein for cancer treatment |
| US20190336599A1 (en) * | 2016-04-15 | 2019-11-07 | Eli Lilly And Company | Combination of ramucirumab and merestinib for use in treatment of colorectal cancer |
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| CN107561625A (zh) * | 2016-06-30 | 2018-01-09 | 扬升照明股份有限公司 | 光源模组以及导光板 |
| KR20190062515A (ko) | 2016-10-06 | 2019-06-05 | 화이자 인코포레이티드 | 암의 치료를 위한 아벨루맙의 투약 용법 |
| JP6709340B2 (ja) | 2016-11-16 | 2020-06-10 | イーライ リリー アンド カンパニー | エクソン14スキッピング変異(複数可)またはエクソン14スキッピング表現型を有するがんの併用療法 |
| RU2765997C2 (ru) | 2017-03-30 | 2022-02-07 | Мерк Патент Гмбх | Комбинация анти-pd-l1 антитела и ингибитора днк-пк для лечения злокачественного новообразования |
| MX2020011684A (es) | 2018-05-04 | 2020-12-10 | Merck Patent Gmbh | Inhibicion combinada de pd-1/pd-l1, tgfbeta y dna-pk para el tratamiento del cancer. |
| KR20210066837A (ko) | 2018-09-26 | 2021-06-07 | 메르크 파텐트 게엠베하 | 암 치료를 위한 pd-1 안타고니스트, atr 억제제 및 백금화제의 조합 |
| US20220252603A1 (en) * | 2019-06-06 | 2022-08-11 | Apollomics Inc. (Hangzhou) | Method for treating cancer patients using c-met inhibitor |
| WO2021084124A1 (en) | 2019-11-01 | 2021-05-06 | Ares Trading S.A. | COMBINED INHIBITION OF PD-1, TGFβ AND ATM TOGETHER WITH RADIOTHERAPY FOR THE TREATMENT OF CANCER |
| WO2021224293A1 (en) * | 2020-05-07 | 2021-11-11 | Ventana Medical Systems, Inc. | Histochemical systems and methods for evaluating egfr and egfr ligand expression in tumor samples |
| DE102020005002A1 (de) * | 2020-08-17 | 2022-02-17 | Epo Experimentelle Pharmakologie & Onkologie Berlin-Buch Gmbh | Mittel zur Therapie von Tumorerkrankungen |
| TW202309094A (zh) * | 2021-05-18 | 2023-03-01 | 美商健生生物科技公司 | 用於識別癌症患者以進行組合治療之方法 |
| CN114512183B (zh) * | 2022-01-27 | 2022-09-20 | 北京吉因加医学检验实验室有限公司 | 一种预测met基因扩增或多倍体的方法及装置 |
| CN115678993B (zh) * | 2022-01-27 | 2025-09-02 | 上海爱谱蒂康生物科技有限公司 | 一种生物标志物组合、含其的试剂及其应用 |
| TW202527997A (zh) * | 2023-11-15 | 2025-07-16 | 大陸商四川科倫博泰生物醫藥股份有限公司 | 靶向egfr/c—met之抗體—藥物結合物以及其製備方法及用途 |
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2011
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- 2011-08-31 EP EP11754597.0A patent/EP2612151B1/en active Active
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- 2011-08-31 JP JP2013526209A patent/JP2013537966A/ja active Pending
- 2011-08-31 BR BR112013004673A patent/BR112013004673A8/pt not_active IP Right Cessation
- 2011-08-31 AU AU2011295919A patent/AU2011295919A1/en not_active Abandoned
- 2011-08-31 RU RU2013114360/15A patent/RU2013114360A/ru not_active Application Discontinuation
- 2011-08-31 EP EP17183227.2A patent/EP3264089A1/en not_active Withdrawn
- 2011-08-31 SG SG10201408229WA patent/SG10201408229WA/en unknown
- 2011-08-31 CA CA2808236A patent/CA2808236A1/en not_active Abandoned
- 2011-08-31 CN CN2011800517811A patent/CN103221825A/zh active Pending
- 2011-08-31 SG SG2013011911A patent/SG187886A1/en unknown
- 2011-08-31 DK DK11754597.0T patent/DK2612151T3/en active
- 2011-08-31 US US13/223,173 patent/US20120089541A1/en not_active Abandoned
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2015
- 2015-12-25 JP JP2015253669A patent/JP2016105096A/ja active Pending
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2016
- 2016-10-26 IL IL248530A patent/IL248530A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2013114360A (ru) | 2014-10-10 |
| JP2013537966A (ja) | 2013-10-07 |
| IL248530A0 (en) | 2016-12-29 |
| AU2011295919A1 (en) | 2013-03-07 |
| CN103221825A (zh) | 2013-07-24 |
| KR20130103734A (ko) | 2013-09-24 |
| EP2612151B1 (en) | 2017-08-09 |
| US20140037625A1 (en) | 2014-02-06 |
| BR112013004673A2 (pt) | 2016-08-02 |
| WO2012031027A1 (en) | 2012-03-08 |
| MX2013002084A (es) | 2013-05-09 |
| DK2612151T3 (en) | 2017-10-02 |
| JP2016105096A (ja) | 2016-06-09 |
| EP3264089A1 (en) | 2018-01-03 |
| US20120089541A1 (en) | 2012-04-12 |
| EP2612151A1 (en) | 2013-07-10 |
| BR112013004673A8 (pt) | 2018-01-02 |
| SG187886A1 (en) | 2013-04-30 |
| ES2641916T3 (es) | 2017-11-14 |
| CA2808236A1 (en) | 2012-03-08 |
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