RU2505544C2 - Антитела против tenb2, сконструированные с цистеином, и конъюгаты антитело - лекарственное средство - Google Patents

Антитела против tenb2, сконструированные с цистеином, и конъюгаты антитело - лекарственное средство Download PDF

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RU2505544C2
RU2505544C2 RU2010119937/10A RU2010119937A RU2505544C2 RU 2505544 C2 RU2505544 C2 RU 2505544C2 RU 2010119937/10 A RU2010119937/10 A RU 2010119937/10A RU 2010119937 A RU2010119937 A RU 2010119937A RU 2505544 C2 RU2505544 C2 RU 2505544C2
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antibody
tenb2
drug
cysteine
conjugate
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RU2010119937/10A
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English (en)
Russian (ru)
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RU2010119937A (ru
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Вэйгуан МАО
Джагатх Редди ДЖУНУТУЛА
Пол Полакис
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Дженентек, Инк.
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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RU2010119937/10A 2007-10-19 2008-10-16 Антитела против tenb2, сконструированные с цистеином, и конъюгаты антитело - лекарственное средство RU2505544C2 (ru)

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Application Number Priority Date Filing Date Title
US98141107P 2007-10-19 2007-10-19
US60/981,411 2007-10-19
PCT/US2008/080102 WO2009052249A1 (en) 2007-10-19 2008-10-16 Cysteine engineered anti-tenb2 antibodies and antibody drug conjugates

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RU2010119937A RU2010119937A (ru) 2011-11-27
RU2505544C2 true RU2505544C2 (ru) 2014-01-27

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US (3) US8937161B2 (enExample)
EP (1) EP2209808B1 (enExample)
JP (2) JP5606916B2 (enExample)
KR (1) KR101622412B1 (enExample)
CN (1) CN101835803B (enExample)
AR (1) AR068941A1 (enExample)
AU (2) AU2008312457B2 (enExample)
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CL (1) CL2008003074A1 (enExample)
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ES (1) ES2450755T3 (enExample)
IL (1) IL204159A (enExample)
MX (1) MX2010003718A (enExample)
MY (1) MY188455A (enExample)
NZ (1) NZ584514A (enExample)
PE (2) PE20140833A1 (enExample)
RU (1) RU2505544C2 (enExample)
TW (1) TWI438004B (enExample)
WO (1) WO2009052249A1 (enExample)
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2728101C2 (ru) * 2015-09-22 2020-07-28 Байондис Б.В. Лечение syd985 пациентов с t-dm1 рефрактерным раком
RU2737727C2 (ru) * 2013-04-16 2020-12-02 Дженентек, Инк. Варианты пертузумаба и их аналитическая характеристика

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