RU2437877C2 - Новые производные тиофена в качестве агонистов рецептора s1p1/edg1 - Google Patents

Новые производные тиофена в качестве агонистов рецептора s1p1/edg1 Download PDF

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Publication number
RU2437877C2
RU2437877C2 RU2008132802/04A RU2008132802A RU2437877C2 RU 2437877 C2 RU2437877 C2 RU 2437877C2 RU 2008132802/04 A RU2008132802/04 A RU 2008132802/04A RU 2008132802 A RU2008132802 A RU 2008132802A RU 2437877 C2 RU2437877 C2 RU 2437877C2
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Russia
Prior art keywords
isobutyl
hydroxy
oxadiazol
methylthiophen
compound according
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RU2008132802/04A
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English (en)
Russian (ru)
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RU2008132802A (ru
Inventor
Мартин БОЛЛИ (CH)
Мартин БОЛЛИ
Давид ЛЕМАНН (CH)
Давид ЛЕМАНН
Борис МАТИС (CH)
Борис МАТИС
Клаус МЮЛЛЕР (DE)
Клаус Мюллер
Оливер НАЙЛЕР (CH)
Оливер НАЙЛЕР
Беат ШТАЙНЕР (CH)
Беат ШТАЙНЕР
Йёрг ФЕЛЬКЕР (FR)
Йёрг ФЕЛЬКЕР
Original Assignee
Актелион Фармасьютиклз Лтд
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Application filed by Актелион Фармасьютиклз Лтд filed Critical Актелион Фармасьютиклз Лтд
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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RU2008132802/04A 2006-01-11 2007-01-10 Новые производные тиофена в качестве агонистов рецептора s1p1/edg1 RU2437877C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006050103 2006-01-11
IBPCT/IB2006/050103 2006-01-11

Publications (2)

Publication Number Publication Date
RU2008132802A RU2008132802A (ru) 2010-02-20
RU2437877C2 true RU2437877C2 (ru) 2011-12-27

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Country Status (17)

Country Link
US (1) US8003800B2 (https=)
EP (1) EP1976512B1 (https=)
JP (1) JP5114430B2 (https=)
KR (1) KR101382710B1 (https=)
CN (1) CN101370496B (https=)
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