KR101382710B1 - 신규한 티오펜 유도체 - Google Patents

신규한 티오펜 유도체 Download PDF

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Publication number
KR101382710B1
KR101382710B1 KR1020087018081A KR20087018081A KR101382710B1 KR 101382710 B1 KR101382710 B1 KR 101382710B1 KR 1020087018081 A KR1020087018081 A KR 1020087018081A KR 20087018081 A KR20087018081 A KR 20087018081A KR 101382710 B1 KR101382710 B1 KR 101382710B1
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South Korea
Prior art keywords
hydroxy
methyl
isobutyl
thiophen
propyl
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Expired - Fee Related
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KR1020087018081A
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Korean (ko)
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KR20080083010A (ko
Inventor
마틴 볼리
데이비드 레흐만
보리스 매티스
클라우스 무엘레르
올리버 네이레르
비트 스테이네르
조르그 벨케르
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액테리온 파마슈티칼 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Life Sciences & Earth Sciences (AREA)
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  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Diabetes (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
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KR1020087018081A 2006-01-11 2007-01-10 신규한 티오펜 유도체 Expired - Fee Related KR101382710B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IB2006050103 2006-01-11
IBPCT/IB2006/050103 2006-01-11
PCT/IB2007/050070 WO2007080542A1 (en) 2006-01-11 2007-01-10 Novel thiophene derivatives as s1p1/edg1 receptor agonists

Publications (2)

Publication Number Publication Date
KR20080083010A KR20080083010A (ko) 2008-09-12
KR101382710B1 true KR101382710B1 (ko) 2014-04-08

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KR1020087018081A Expired - Fee Related KR101382710B1 (ko) 2006-01-11 2007-01-10 신규한 티오펜 유도체

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Country Link
US (1) US8003800B2 (https=)
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CA2635047A1 (en) 2007-07-19
WO2007080542A1 (en) 2007-07-19
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