RU2017139267A - Усовершенствованные способы выделения рекомбинантных белков - Google Patents

Усовершенствованные способы выделения рекомбинантных белков Download PDF

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Publication number
RU2017139267A
RU2017139267A RU2017139267A RU2017139267A RU2017139267A RU 2017139267 A RU2017139267 A RU 2017139267A RU 2017139267 A RU2017139267 A RU 2017139267A RU 2017139267 A RU2017139267 A RU 2017139267A RU 2017139267 A RU2017139267 A RU 2017139267A
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Russia
Prior art keywords
level
recombinant protein
host cell
prokaryotic host
homogenization
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RU2017139267A
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English (en)
Russian (ru)
Inventor
Майкл У. ЛЕЙРД
Ричард СТ. ДЖОН
Джейн В. ГАНСОН
Ким КАЛЕАС
Дипа НАДАРАДЖА
Рэйчел АДАМС
Брэдли Р. СНЕДЕКОР
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Дженентек, Инк.
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Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of RU2017139267A publication Critical patent/RU2017139267A/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/42—Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2017139267A 2012-03-27 2013-03-14 Усовершенствованные способы выделения рекомбинантных белков RU2017139267A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616297P 2012-03-27 2012-03-27
US61/616,297 2012-03-27

Related Parent Applications (1)

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RU2014137554A Division RU2636353C2 (ru) 2012-03-27 2013-03-14 Усовершенствованные способы выделения рекобинантных белков

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RU2017139267A true RU2017139267A (ru) 2019-02-12

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RU2017139267A RU2017139267A (ru) 2012-03-27 2013-03-14 Усовершенствованные способы выделения рекомбинантных белков
RU2014137554A RU2636353C2 (ru) 2012-03-27 2013-03-14 Усовершенствованные способы выделения рекобинантных белков

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US (9) US20140080180A1 (enExample)
EP (1) EP2831261B1 (enExample)
JP (4) JP6225162B2 (enExample)
KR (2) KR20200037425A (enExample)
CN (2) CN109880867A (enExample)
AR (2) AR090340A1 (enExample)
AU (3) AU2013240280A1 (enExample)
BR (1) BR112014023176B1 (enExample)
CA (2) CA3086730A1 (enExample)
ES (1) ES2654424T3 (enExample)
HR (1) HRP20171966T1 (enExample)
IL (1) IL234377B (enExample)
MX (3) MX365947B (enExample)
MY (1) MY171729A (enExample)
PL (1) PL2831261T3 (enExample)
RU (2) RU2017139267A (enExample)
SG (4) SG10202007206WA (enExample)
SI (1) SI2831261T1 (enExample)
WO (1) WO2013148249A1 (enExample)
ZA (1) ZA201406434B (enExample)

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CN110305903B (zh) * 2019-07-31 2021-10-01 江苏璟泽生物医药有限公司 重组人促卵泡激素及其制备方法
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Publication number Publication date
RU2636353C2 (ru) 2017-11-22
BR112014023176B1 (pt) 2021-09-28
US20250137027A1 (en) 2025-05-01
CN109880867A (zh) 2019-06-14
SG10202007206WA (en) 2020-08-28
CN104350156A (zh) 2015-02-11
US20240158825A1 (en) 2024-05-16
MX365947B (es) 2019-06-19
SG10201912877SA (en) 2020-02-27
KR20140148392A (ko) 2014-12-31
KR20200037425A (ko) 2020-04-08
EP2831261A1 (en) 2015-02-04
MX2019007032A (es) 2019-08-16
CA3086730A1 (en) 2013-10-03
JP2018046825A (ja) 2018-03-29
HK1207120A1 (en) 2016-01-22
JP2020202849A (ja) 2020-12-24
ES2654424T3 (es) 2018-02-13
JP2019141049A (ja) 2019-08-29
RU2014137554A (ru) 2016-05-20
IL234377B (en) 2021-01-31
CN104350156B (zh) 2019-04-02
SI2831261T1 (en) 2018-01-31
US20150225760A1 (en) 2015-08-13
AU2017202484B2 (en) 2019-06-13
KR102096678B1 (ko) 2020-04-02
CA2866753A1 (en) 2013-10-03
SG11201406112TA (en) 2014-10-30
HRP20171966T1 (hr) 2018-02-09
AU2017202484A1 (en) 2017-05-04
MY171729A (en) 2019-10-25
SG10201508420VA (en) 2015-11-27
US20200199639A1 (en) 2020-06-25
AU2019226192A1 (en) 2019-09-26
JP6225162B2 (ja) 2017-11-01
CA2866753C (en) 2020-09-22
AR090340A1 (es) 2014-11-05
WO2013148249A1 (en) 2013-10-03
MX2014011558A (es) 2014-11-14
US20140080180A1 (en) 2014-03-20
US20160130624A1 (en) 2016-05-12
PL2831261T3 (pl) 2018-04-30
EP2831261B1 (en) 2017-10-18
BR112014023176A2 (pt) 2017-06-20
ZA201406434B (en) 2017-08-30
JP2015512259A (ja) 2015-04-27
US20230069966A1 (en) 2023-03-09
US20180291411A1 (en) 2018-10-11
MX2018007677A (es) 2020-11-12
AR116615A2 (es) 2021-05-26
AU2013240280A1 (en) 2014-10-16
US9765379B2 (en) 2017-09-19
US20210171997A1 (en) 2021-06-10

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