JP6225162B2 - 組換えタンパク質の改良された収集操作 - Google Patents

組換えタンパク質の改良された収集操作 Download PDF

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Publication number
JP6225162B2
JP6225162B2 JP2015503300A JP2015503300A JP6225162B2 JP 6225162 B2 JP6225162 B2 JP 6225162B2 JP 2015503300 A JP2015503300 A JP 2015503300A JP 2015503300 A JP2015503300 A JP 2015503300A JP 6225162 B2 JP6225162 B2 JP 6225162B2
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recombinant protein
antibody
recombinant
protein
host cell
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Japanese (ja)
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JP2015512259A5 (enExample
JP2015512259A (ja
Inventor
マイケル ダブリュ． レアード，
マイケル ダブリュ． レアード，
ジョン， リチャード セント
ジョン， リチャード セント
ジェーン ヴィー． ガンソン，
ジェーン ヴィー． ガンソン，
キム カレアス，
キム カレアス，
ディーパ ナダラジャ，
ディーパ ナダラジャ，
レイチェル アダムズ，
レイチェル アダムズ，
ブラッドリー アール． スネデカー，
ブラッドリー アール． スネデカー，
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Genentech Inc
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Genentech Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40—Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/42—Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2015503300A 2012-03-27 2013-03-14 組換えタンパク質の改良された収集操作 Active JP6225162B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261616297P 2012-03-27 2012-03-27
US61/616,297 2012-03-27
PCT/US2013/031383 WO2013148249A1 (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Related Child Applications (1)

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JP2017195016A Division JP2018046825A (ja) 2012-03-27 2017-10-05 組換えタンパク質の改良された収集操作

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JP2015512259A JP2015512259A (ja) 2015-04-27
JP2015512259A5 JP2015512259A5 (enExample) 2016-05-12
JP6225162B2 true JP6225162B2 (ja) 2017-11-01

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JP2015503300A Active JP6225162B2 (ja) 2012-03-27 2013-03-14 組換えタンパク質の改良された収集操作
JP2017195016A Pending JP2018046825A (ja) 2012-03-27 2017-10-05 組換えタンパク質の改良された収集操作
JP2019049717A Withdrawn JP2019141049A (ja) 2012-03-27 2019-03-18 組換えタンパク質の改良された収集操作
JP2020137053A Withdrawn JP2020202849A (ja) 2012-03-27 2020-08-14 組換えタンパク質の改良された収集操作

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JP2017195016A Pending JP2018046825A (ja) 2012-03-27 2017-10-05 組換えタンパク質の改良された収集操作
JP2019049717A Withdrawn JP2019141049A (ja) 2012-03-27 2019-03-18 組換えタンパク質の改良された収集操作
JP2020137053A Withdrawn JP2020202849A (ja) 2012-03-27 2020-08-14 組換えタンパク質の改良された収集操作

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US (9) US20140080180A1 (enExample)
EP (1) EP2831261B1 (enExample)
JP (4) JP6225162B2 (enExample)
KR (2) KR102096678B1 (enExample)
CN (2) CN109880867A (enExample)
AR (2) AR090340A1 (enExample)
AU (3) AU2013240280A1 (enExample)
BR (1) BR112014023176B1 (enExample)
CA (2) CA3086730A1 (enExample)
ES (1) ES2654424T3 (enExample)
HR (1) HRP20171966T1 (enExample)
IL (1) IL234377B (enExample)
MX (3) MX365947B (enExample)
MY (1) MY171729A (enExample)
PL (1) PL2831261T3 (enExample)
RU (2) RU2017139267A (enExample)
SG (4) SG11201406112TA (enExample)
SI (1) SI2831261T1 (enExample)
WO (1) WO2013148249A1 (enExample)
ZA (1) ZA201406434B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0755972B2 (ja) 1988-11-18 1995-06-14 キュー２１００，インコーポレーテッド プラスチックレンズ組成物

Families Citing this family (8)

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JP2019517272A (ja) * 2016-06-10 2019-06-24 ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ タンパク質の安定化方法
KR102595048B1 (ko) * 2016-11-07 2023-10-26 씨젠 인크. 조작된-시스테인 캡의 분포
US20210024873A1 (en) * 2018-03-27 2021-01-28 Bristol-Myers Squibb Company Real-time monitoring of protein concentration using ultraviolet signal
FI3857237T3 (fi) * 2019-01-16 2023-05-03 Regeneron Pharma Disulfidisidosten luonnehtimismenetelmiä
CN109725088B (zh) * 2019-03-16 2021-05-18 丁立平 一种测定豆芽中2-萘甲酸及其衍生物的气相色谱-质谱联用法
CN110305903B (zh) * 2019-07-31 2021-10-01 江苏璟泽生物医药有限公司 重组人促卵泡激素及其制备方法
CN113155776A (zh) * 2021-04-29 2021-07-23 华东交通大学 一种柑桔最佳采收期预测方法
FR3146146A1 (fr) 2023-02-24 2024-08-30 Bgene Genetics Production d’acide 1-4-dihydroxy-2-naphtoïque par Escherichia coli

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0755972B2 (ja) 1988-11-18 1995-06-14 キュー２１００，インコーポレーテッド プラスチックレンズ組成物

Also Published As

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AR090340A1 (es) 2014-11-05
KR20200037425A (ko) 2020-04-08
HK1207120A1 (en) 2016-01-22
US20200199639A1 (en) 2020-06-25
SI2831261T1 (en) 2018-01-31
EP2831261B1 (en) 2017-10-18
RU2014137554A (ru) 2016-05-20
RU2017139267A (ru) 2019-02-12
SG10201912877SA (en) 2020-02-27
JP2020202849A (ja) 2020-12-24
MX365947B (es) 2019-06-19
CA2866753A1 (en) 2013-10-03
US20240158825A1 (en) 2024-05-16
BR112014023176A2 (pt) 2017-06-20
CA2866753C (en) 2020-09-22
KR102096678B1 (ko) 2020-04-02
AU2017202484B2 (en) 2019-06-13
US20180291411A1 (en) 2018-10-11
RU2636353C2 (ru) 2017-11-22
JP2018046825A (ja) 2018-03-29
SG11201406112TA (en) 2014-10-30
JP2015512259A (ja) 2015-04-27
MX2019007032A (es) 2019-08-16
MX2014011558A (es) 2014-11-14
ZA201406434B (en) 2017-08-30
US9765379B2 (en) 2017-09-19
MX2018007677A (es) 2020-11-12
SG10202007206WA (en) 2020-08-28
CN104350156A (zh) 2015-02-11
BR112014023176B1 (pt) 2021-09-28
AU2013240280A1 (en) 2014-10-16
EP2831261A1 (en) 2015-02-04
CN109880867A (zh) 2019-06-14
US20150225760A1 (en) 2015-08-13
WO2013148249A1 (en) 2013-10-03
AR116615A2 (es) 2021-05-26
MY171729A (en) 2019-10-25
AU2019226192A1 (en) 2019-09-26
US20140080180A1 (en) 2014-03-20
JP2019141049A (ja) 2019-08-29
IL234377B (en) 2021-01-31
PL2831261T3 (pl) 2018-04-30
HRP20171966T1 (hr) 2018-02-09
CA3086730A1 (en) 2013-10-03
AU2017202484A1 (en) 2017-05-04
KR20140148392A (ko) 2014-12-31
SG10201508420VA (en) 2015-11-27
US20250137027A1 (en) 2025-05-01
US20230069966A1 (en) 2023-03-09
CN104350156B (zh) 2019-04-02
ES2654424T3 (es) 2018-02-13
US20160130624A1 (en) 2016-05-12
US20210171997A1 (en) 2021-06-10

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