CA3086730A1 - Improved harvest operations for recombinant proteins - Google Patents

Improved harvest operations for recombinant proteins

Info

Publication number
CA3086730A1
CA3086730A1 CA3086730A CA3086730A CA3086730A1 CA 3086730 A1 CA3086730 A1 CA 3086730A1 CA 3086730 A CA3086730 A CA 3086730A CA 3086730 A CA3086730 A CA 3086730A CA 3086730 A1 CA3086730 A1 CA 3086730A1
Authority
CA
Canada
Prior art keywords
recombinant protein
host cell
prokaryotic host
antibodies
maintained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA3086730A
Other languages
English (en)
French (fr)
Inventor
Michael W. Laird
Richard St. John
Jane V. GUNSON
Kim KALEAS
Deepa NADARAJAH
Bradley R. Snedecor
Rachel Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA3086730A1 publication Critical patent/CA3086730A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/40Means for regulation, monitoring, measurement or control, e.g. flow regulation of pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/42Means for regulation, monitoring, measurement or control, e.g. flow regulation of agitation speed
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Sustainable Development (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA3086730A 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins Abandoned CA3086730A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261616297P 2012-03-27 2012-03-27
US61/616,297 2012-03-27
CA2866753A CA2866753C (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2866753A Division CA2866753C (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Publications (1)

Publication Number Publication Date
CA3086730A1 true CA3086730A1 (en) 2013-10-03

Family

ID=48040433

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3086730A Abandoned CA3086730A1 (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins
CA2866753A Active CA2866753C (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2866753A Active CA2866753C (en) 2012-03-27 2013-03-14 Improved harvest operations for recombinant proteins

Country Status (20)

Country Link
US (9) US20140080180A1 (enExample)
EP (1) EP2831261B1 (enExample)
JP (4) JP6225162B2 (enExample)
KR (2) KR102096678B1 (enExample)
CN (2) CN109880867A (enExample)
AR (2) AR090340A1 (enExample)
AU (3) AU2013240280A1 (enExample)
BR (1) BR112014023176B1 (enExample)
CA (2) CA3086730A1 (enExample)
ES (1) ES2654424T3 (enExample)
HR (1) HRP20171966T1 (enExample)
IL (1) IL234377B (enExample)
MX (3) MX365947B (enExample)
MY (1) MY171729A (enExample)
PL (1) PL2831261T3 (enExample)
RU (2) RU2017139267A (enExample)
SG (4) SG11201406112TA (enExample)
SI (1) SI2831261T1 (enExample)
WO (1) WO2013148249A1 (enExample)
ZA (1) ZA201406434B (enExample)

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JP2019517272A (ja) * 2016-06-10 2019-06-24 ロンザ リミテッドLonza Limited タンパク質の安定化方法
KR102595048B1 (ko) * 2016-11-07 2023-10-26 씨젠 인크. 조작된-시스테인 캡의 분포
US20210024873A1 (en) * 2018-03-27 2021-01-28 Bristol-Myers Squibb Company Real-time monitoring of protein concentration using ultraviolet signal
FI3857237T3 (fi) * 2019-01-16 2023-05-03 Regeneron Pharma Disulfidisidosten luonnehtimismenetelmiä
CN109725088B (zh) * 2019-03-16 2021-05-18 丁立平 一种测定豆芽中2-萘甲酸及其衍生物的气相色谱-质谱联用法
CN110305903B (zh) * 2019-07-31 2021-10-01 江苏璟泽生物医药有限公司 重组人促卵泡激素及其制备方法
CN113155776A (zh) * 2021-04-29 2021-07-23 华东交通大学 一种柑桔最佳采收期预测方法
FR3146146A1 (fr) 2023-02-24 2024-08-30 Bgene Genetics Production d’acide 1-4-dihydroxy-2-naphtoïque par Escherichia coli

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Also Published As

Publication number Publication date
AR090340A1 (es) 2014-11-05
KR20200037425A (ko) 2020-04-08
HK1207120A1 (en) 2016-01-22
US20200199639A1 (en) 2020-06-25
SI2831261T1 (en) 2018-01-31
EP2831261B1 (en) 2017-10-18
RU2014137554A (ru) 2016-05-20
RU2017139267A (ru) 2019-02-12
SG10201912877SA (en) 2020-02-27
JP2020202849A (ja) 2020-12-24
MX365947B (es) 2019-06-19
CA2866753A1 (en) 2013-10-03
US20240158825A1 (en) 2024-05-16
BR112014023176A2 (pt) 2017-06-20
CA2866753C (en) 2020-09-22
KR102096678B1 (ko) 2020-04-02
AU2017202484B2 (en) 2019-06-13
US20180291411A1 (en) 2018-10-11
RU2636353C2 (ru) 2017-11-22
JP2018046825A (ja) 2018-03-29
SG11201406112TA (en) 2014-10-30
JP2015512259A (ja) 2015-04-27
MX2019007032A (es) 2019-08-16
MX2014011558A (es) 2014-11-14
ZA201406434B (en) 2017-08-30
US9765379B2 (en) 2017-09-19
MX2018007677A (es) 2020-11-12
SG10202007206WA (en) 2020-08-28
CN104350156A (zh) 2015-02-11
BR112014023176B1 (pt) 2021-09-28
AU2013240280A1 (en) 2014-10-16
EP2831261A1 (en) 2015-02-04
CN109880867A (zh) 2019-06-14
US20150225760A1 (en) 2015-08-13
JP6225162B2 (ja) 2017-11-01
WO2013148249A1 (en) 2013-10-03
AR116615A2 (es) 2021-05-26
MY171729A (en) 2019-10-25
AU2019226192A1 (en) 2019-09-26
US20140080180A1 (en) 2014-03-20
JP2019141049A (ja) 2019-08-29
IL234377B (en) 2021-01-31
PL2831261T3 (pl) 2018-04-30
HRP20171966T1 (hr) 2018-02-09
AU2017202484A1 (en) 2017-05-04
KR20140148392A (ko) 2014-12-31
SG10201508420VA (en) 2015-11-27
US20250137027A1 (en) 2025-05-01
US20230069966A1 (en) 2023-03-09
CN104350156B (zh) 2019-04-02
ES2654424T3 (es) 2018-02-13
US20160130624A1 (en) 2016-05-12
US20210171997A1 (en) 2021-06-10

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20220104

FZDE Discontinued

Effective date: 20220104