RU2016103149A - Пестицидно-активные би-или трициклические гетероциклы с серосодержащими заместителями - Google Patents
Пестицидно-активные би-или трициклические гетероциклы с серосодержащими заместителями Download PDFInfo
- Publication number
- RU2016103149A RU2016103149A RU2016103149A RU2016103149A RU2016103149A RU 2016103149 A RU2016103149 A RU 2016103149A RU 2016103149 A RU2016103149 A RU 2016103149A RU 2016103149 A RU2016103149 A RU 2016103149A RU 2016103149 A RU2016103149 A RU 2016103149A
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- cycloalkyl
- haloalkyl
- alkynyl
- alkenyl
- Prior art date
Links
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 76
- 125000004765 (C1-C4) haloalkyl group Chemical group 0.000 claims 56
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 claims 54
- 125000000882 C2-C6 alkenyl group Chemical group 0.000 claims 47
- 125000006643 (C2-C6) haloalkenyl group Chemical group 0.000 claims 46
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 claims 46
- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims 46
- 229910052757 nitrogen Inorganic materials 0.000 claims 38
- 229910052736 halogen Inorganic materials 0.000 claims 33
- 150000002367 halogens Chemical class 0.000 claims 26
- 125000006677 (C1-C3) haloalkoxy group Chemical group 0.000 claims 23
- 229910052739 hydrogen Inorganic materials 0.000 claims 19
- 239000001257 hydrogen Substances 0.000 claims 19
- 150000001875 compounds Chemical class 0.000 claims 17
- -1 cyano, hydroxy Chemical group 0.000 claims 16
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 claims 14
- 125000001424 substituent group Chemical group 0.000 claims 14
- 150000002431 hydrogen Chemical class 0.000 claims 12
- 125000004093 cyano group Chemical group *C#N 0.000 claims 11
- 229910052799 carbon Inorganic materials 0.000 claims 10
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 claims 9
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 claims 9
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 claims 9
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 claims 8
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 claims 8
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 claims 8
- 125000004740 (C1-C6) haloalkylsulfanyl group Chemical group 0.000 claims 7
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 7
- BTIIGNUPPKUQAP-UHFFFAOYSA-N [1-[2,3-dihydroxy-4-[4-(oxoazaniumylmethylidene)pyridin-1-yl]butyl]pyridin-4-ylidene]methyl-oxoazanium;diperchlorate Chemical compound [O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O.C1=CC(=C[NH+]=O)C=CN1CC(O)C(O)CN1C=CC(=C[NH+]=O)C=C1 BTIIGNUPPKUQAP-UHFFFAOYSA-N 0.000 claims 6
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 6
- 125000006766 (C2-C6) alkynyloxy group Chemical group 0.000 claims 5
- 125000006765 (C2-C6) haloalkenyloxy group Chemical group 0.000 claims 5
- 125000006767 (C2-C6) haloalkynyloxy group Chemical group 0.000 claims 5
- 125000003320 C2-C6 alkenyloxy group Chemical group 0.000 claims 5
- 241000607479 Yersinia pestis Species 0.000 claims 5
- 125000004890 (C1-C6) alkylamino group Chemical group 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 229910052717 sulfur Inorganic materials 0.000 claims 4
- 125000002373 5 membered heterocyclic group Chemical group 0.000 claims 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 3
- 230000000895 acaricidal effect Effects 0.000 claims 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 3
- 230000000749 insecticidal effect Effects 0.000 claims 3
- 230000002013 molluscicidal effect Effects 0.000 claims 3
- 230000001069 nematicidal effect Effects 0.000 claims 3
- 229910052760 oxygen Inorganic materials 0.000 claims 3
- 239000001301 oxygen Substances 0.000 claims 3
- 239000011593 sulfur Substances 0.000 claims 3
- 125000004070 6 membered heterocyclic group Chemical group 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 150000001204 N-oxides Chemical class 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000004663 dialkyl amino group Chemical group 0.000 claims 2
- 125000004430 oxygen atom Chemical group O* 0.000 claims 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
- 125000004434 sulfur atom Chemical group 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000006728 (C1-C6) alkynyl group Chemical group 0.000 claims 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 238000002405 diagnostic procedure Methods 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 125000004692 haloalkylcarbonyl group Chemical group 0.000 claims 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 claims 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 238000011477 surgical intervention Methods 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 125000003396 thiol group Chemical class [H]S* 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13174698.4 | 2013-07-02 | ||
| EP13174698 | 2013-07-02 | ||
| EP13176263 | 2013-07-12 | ||
| EP13176263.5 | 2013-07-12 | ||
| EP13197069.1 | 2013-12-13 | ||
| EP13197069 | 2013-12-13 | ||
| CN2014076736 | 2014-05-04 | ||
| CNPCT/CN2014/076736 | 2014-05-04 | ||
| PCT/EP2014/062946 WO2015000715A1 (en) | 2013-07-02 | 2014-06-19 | Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016103149A true RU2016103149A (ru) | 2017-08-07 |
| RU2016103149A3 RU2016103149A3 (enExample) | 2018-04-28 |
Family
ID=50976655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016103149A RU2016103149A (ru) | 2013-07-02 | 2014-06-19 | Пестицидно-активные би-или трициклические гетероциклы с серосодержащими заместителями |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10939682B2 (enExample) |
| EP (3) | EP3016949B1 (enExample) |
| JP (1) | JP6677637B2 (enExample) |
| BR (1) | BR112016000059B1 (enExample) |
| CA (1) | CA2917262A1 (enExample) |
| ES (1) | ES2807599T3 (enExample) |
| HU (1) | HUE049733T2 (enExample) |
| MX (1) | MX2015017821A (enExample) |
| RU (1) | RU2016103149A (enExample) |
| TW (1) | TW201536781A (enExample) |
| WO (1) | WO2015000715A1 (enExample) |
Families Citing this family (156)
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| WO2012088266A2 (en) | 2010-12-22 | 2012-06-28 | Incyte Corporation | Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3 |
| SI2861595T1 (sl) | 2012-06-13 | 2017-04-26 | Incyte Holdings Corporation | Substituirane triciklične spojine kot inhibitorji fgfr |
| US9388185B2 (en) | 2012-08-10 | 2016-07-12 | Incyte Holdings Corporation | Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors |
| US9266892B2 (en) | 2012-12-19 | 2016-02-23 | Incyte Holdings Corporation | Fused pyrazoles as FGFR inhibitors |
| LT2986610T (lt) | 2013-04-19 | 2018-04-10 | Incyte Holdings Corporation | Bicikliniai heterociklai, kaip fgfr inhibitoriai |
| TWI652014B (zh) * | 2013-09-13 | 2019-03-01 | 美商艾佛艾姆希公司 | 雜環取代之雙環唑殺蟲劑 |
| ES2987367T3 (es) * | 2014-02-17 | 2024-11-14 | Bayer Cropscience Ag | Derivados de heterociclos bicíclicos condensados sustituidos con 2-(het)arilo como agentes para combatir parásitos |
| JP6689821B2 (ja) | 2014-08-12 | 2020-04-28 | シンジェンタ パーティシペーションズ アーゲー | 硫黄含有置換基を有する殺有害生物的に活性な複素環式誘導体 |
| JP6695326B2 (ja) * | 2014-08-21 | 2020-05-20 | シンジェンタ パーティシペーションズ アーゲー | 硫黄含有置換基を有する殺有害生物的に活性な複素環式誘導体 |
| WO2016039444A1 (ja) * | 2014-09-12 | 2016-03-17 | 日本農薬株式会社 | イミダゾピリダジン化合物又はその塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法 |
| WO2016039441A1 (ja) * | 2014-09-12 | 2016-03-17 | 日本農薬株式会社 | イミダゾピリダジン化合物又はその塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法 |
| WO2016058928A1 (en) * | 2014-10-14 | 2016-04-21 | Syngenta Participations Ag | Pesticidally active heterocyclic derivatives with sulphur containing substituents |
| US10851105B2 (en) | 2014-10-22 | 2020-12-01 | Incyte Corporation | Bicyclic heterocycles as FGFR4 inhibitors |
| RU2738359C2 (ru) * | 2014-11-07 | 2020-12-11 | Зингента Партисипейшнс Аг | Пестицидно активные полициклические производные с серосодержащими заместителями |
| EP3230284B1 (en) | 2014-12-11 | 2020-04-15 | Syngenta Participations AG | Pesticidally active tetracyclic derivatives with sulfur containing substituents |
| JP2018052816A (ja) * | 2014-12-26 | 2018-04-05 | 日本農薬株式会社 | シクロアルキル基を有する縮合複素環化合物又はその塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法 |
| EP3247712B1 (en) * | 2015-01-19 | 2022-04-20 | Syngenta Participations AG | Pesticidally active polycyclic derivatives with sulfur containing substituents |
| TWI696612B (zh) * | 2015-01-29 | 2020-06-21 | 日商日本農藥股份有限公司 | 具有環烷基吡啶基的稠合雜環化合物或其鹽類及含有該化合物的農園藝用殺蟲劑以及其使用方法 |
| UY36547A (es) | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
| UY36548A (es) * | 2015-02-05 | 2016-06-01 | Bayer Cropscience Ag | Derivados heterocíclicos condensados bicíclicos sustituidos por 2-(het)arilo como pesticidas |
| PT3257853T (pt) * | 2015-02-12 | 2021-12-23 | Nissan Chemical Corp | Composto heterocíclico condensado e agente de controlo de organismos prejudiciais |
| MA41551A (fr) | 2015-02-20 | 2017-12-26 | Incyte Corp | Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4 |
| SG10201913036RA (en) | 2015-02-20 | 2020-02-27 | Incyte Corp | Bicyclic heterocycles as fgfr inhibitors |
| WO2016134294A1 (en) | 2015-02-20 | 2016-08-25 | Incyte Corporation | Bicyclic heterocycles as fgfr4 inhibitors |
| CN112608300B (zh) * | 2015-03-11 | 2024-04-26 | Fmc公司 | 杂环取代的二环唑杀有害生物剂 |
| MX2017011579A (es) * | 2015-03-12 | 2018-03-15 | Du Pont | Pesticidas de tipo azol bicíclicos sustituidos con un heterociclo. |
| ES2762936T3 (es) * | 2015-03-12 | 2020-05-26 | Syngenta Participations Ag | Derivados tetracíclicos activos como plaguicidas con sustituyentes que contienen azufre |
| BR112017019372B1 (pt) * | 2015-03-12 | 2022-08-16 | Syngenta Participations Ag | Compostos derivados tetracíclicos ativos em termos pesticidas com substituintes contendo enxofre, composição pesticida, método para controle de pragas e método para a proteção de sementes do ataque por pragas |
| ES2779532T3 (es) * | 2015-04-08 | 2020-08-18 | Bayer Cropscience Ag | Derivados de imidazo[1,2a]piridin-2-ilo como pesticidas y sus productos intermedios |
| CN107531704B (zh) * | 2015-04-24 | 2021-01-01 | 先正达参股股份有限公司 | 具有硫取代的五元环杂环的杀有害生物活性多环衍生物 |
| US10125139B2 (en) | 2015-04-24 | 2018-11-13 | Syngenta Crop Protection Ag | Pesticidally active polycyclic derivatives with sulfur substituted five-membered ring heterocycles |
| WO2017001311A1 (en) * | 2015-07-01 | 2017-01-05 | Syngenta Participations Ag | Pesticidally active tetracyclic derivatives with sulfur containing substituents |
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| WO2017026384A1 (ja) * | 2015-08-07 | 2017-02-16 | 日本農薬株式会社 | インダゾール化合物又はその塩類及び該化合物を含有する農園芸用殺虫剤並びにその使用方法 |
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| PE20181094A1 (es) * | 2015-09-28 | 2018-07-09 | Bayer Cropscience Ag | Derivados heterociclicos condensados sustituidos por 2-(het)arilo como pesticidas |
| AU2016332021A1 (en) * | 2015-09-29 | 2018-04-19 | Oncotherapy Science, Inc. | Bicyclic compound and use thereof for inhibiting SUV39H2 |
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| BR122021026497B1 (pt) * | 2015-10-13 | 2022-10-25 | Nihon Nohyaku Co., Ltd | Heterocíclico condensado contendo grupo oxima ou sal deste, inseticida agrícola e hortícola, método para usar o inseticida e agente de controle de ectoparasitas animais |
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-
2014
- 2014-06-19 WO PCT/EP2014/062946 patent/WO2015000715A1/en not_active Ceased
- 2014-06-19 US US14/898,597 patent/US10939682B2/en active Active
- 2014-06-19 JP JP2016522405A patent/JP6677637B2/ja not_active Expired - Fee Related
- 2014-06-19 ES ES14731284T patent/ES2807599T3/es active Active
- 2014-06-19 BR BR112016000059-5A patent/BR112016000059B1/pt active IP Right Grant
- 2014-06-19 HU HUE14731284A patent/HUE049733T2/hu unknown
- 2014-06-19 EP EP14731284.7A patent/EP3016949B1/en active Active
- 2014-06-19 MX MX2015017821A patent/MX2015017821A/es unknown
- 2014-06-19 CA CA2917262A patent/CA2917262A1/en not_active Abandoned
- 2014-06-19 RU RU2016103149A patent/RU2016103149A/ru not_active Application Discontinuation
- 2014-06-19 EP EP20170168.7A patent/EP3778598A3/en not_active Withdrawn
- 2014-06-19 EP EP20170169.5A patent/EP3778599A3/en not_active Withdrawn
- 2014-07-02 TW TW103122814A patent/TW201536781A/zh unknown
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2021
- 2021-12-15 US US17/551,910 patent/US20220104496A1/en not_active Abandoned
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|---|---|
| EP3778599A3 (en) | 2021-04-21 |
| EP3016949A1 (en) | 2016-05-11 |
| TW201536781A (zh) | 2015-10-01 |
| JP6677637B2 (ja) | 2020-04-08 |
| MX2015017821A (es) | 2016-04-15 |
| US10939682B2 (en) | 2021-03-09 |
| EP3778598A3 (en) | 2021-08-04 |
| HUE049733T2 (hu) | 2020-10-28 |
| EP3016949B1 (en) | 2020-05-13 |
| CA2917262A1 (en) | 2015-01-08 |
| BR112016000059A2 (pt) | 2017-07-25 |
| JP2016528189A (ja) | 2016-09-15 |
| BR112016000059B1 (pt) | 2020-12-29 |
| ES2807599T3 (es) | 2021-02-23 |
| WO2015000715A1 (en) | 2015-01-08 |
| EP3778598A2 (en) | 2021-02-17 |
| EP3778599A2 (en) | 2021-02-17 |
| US20160255837A1 (en) | 2016-09-08 |
| US20220104496A1 (en) | 2022-04-07 |
| RU2016103149A3 (enExample) | 2018-04-28 |
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