RU2004139022A - Фармацевтические препараты для орального употребления, содержащие заполненные биологически активными веществами ионообменные смолы, а также структурно-вязкие агенты гелеобразования в качестве загустителей - Google Patents
Фармацевтические препараты для орального употребления, содержащие заполненные биологически активными веществами ионообменные смолы, а также структурно-вязкие агенты гелеобразования в качестве загустителей Download PDFInfo
- Publication number
- RU2004139022A RU2004139022A RU2004139022/15A RU2004139022A RU2004139022A RU 2004139022 A RU2004139022 A RU 2004139022A RU 2004139022/15 A RU2004139022/15 A RU 2004139022/15A RU 2004139022 A RU2004139022 A RU 2004139022A RU 2004139022 A RU2004139022 A RU 2004139022A
- Authority
- RU
- Russia
- Prior art keywords
- biologically active
- pharmaceutical preparation
- ion exchanger
- preparation according
- agents
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (10)
1. Фармацевтический препарат, содержащий одно или несколько связанных с ионитом биологически активных веществ, отличающийся тем, что наполненный ионит диспергирован в среде-носителе, содержащей один или несколько структурно-вязких агентов гелеобразования.
2. Фармацевтический препарат по п.1, отличающийся тем, что в качестве структурно-вязкого агента гелеобразования он содержит полиакриловую кислоту, ксантан, микрокристаллическую целлюлозу, простой эфир целлюлозы, бентонит, высокодисперсный диоксид кремния или смесь указанных агентов гелеобразования.
3. Фармацевтический препарат по п.1, отличающийся тем, что ионит является кислым ионитом.
4. Фармацевтический препарат по п.1, отличающийся тем, что среда-носитель содержит воду.
5. Фармацевтический препарат по п.1, отличающийся тем, что биологически активным веществом, связанным с ионитом, является хинолоновый антибиотик.
6. Фармацевтический препарат по п.1, отличающийся тем, что биологически активным веществом, связанным с ионитом, является прадофлоксацин.
7. Фармацевтический препарат по п.1, отличающийся тем, что биологически активным веществом, связанным с ионитом, является энрофлоксацин.
8. Фармацевтический препарат по п.1, отличающийся тем, что биологически активным веществом, связанным с ионитом, является флупиртин.
9. Применение фармацевтических препаратов по п.1 для орального применения.
10. Применение структурно-вязких агентов гелеобразования для улучшения свойств жидких суспензий, предназначенных для использования в качестве орально применяемых лекарственных средств для животных.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10224086.8 | 2002-05-31 | ||
| DE10224086A DE10224086A1 (de) | 2002-05-31 | 2002-05-31 | Pharmazeutische Zubereitungen zur oralen Anwendung enthaltend wirkstoffbeladene Ionentauscherharze sowie strukturviskose Gelbildner als Verdicker |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2004139022A true RU2004139022A (ru) | 2005-07-10 |
| RU2380091C2 RU2380091C2 (ru) | 2010-01-27 |
Family
ID=29432468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2004139022/15A RU2380091C2 (ru) | 2002-05-31 | 2003-05-19 | Фармацевтические препараты для орального употребления, содержащие заполненные биологически активными веществами ионообменные смолы, а также структурно-вязкие агенты гелеобразования в качестве загустителей |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US8545829B2 (ru) |
| EP (1) | EP1513500B1 (ru) |
| JP (2) | JP5350574B2 (ru) |
| KR (3) | KR20050010015A (ru) |
| CN (1) | CN1671361B (ru) |
| AR (2) | AR039861A1 (ru) |
| AT (1) | ATE421317T1 (ru) |
| AU (1) | AU2003242545B2 (ru) |
| BR (2) | BR0311511A (ru) |
| CA (1) | CA2487648C (ru) |
| CR (1) | CR7598A (ru) |
| DE (2) | DE10224086A1 (ru) |
| DK (1) | DK1513500T3 (ru) |
| ES (1) | ES2319115T3 (ru) |
| HK (1) | HK1083200A1 (ru) |
| HR (1) | HRP20041219B1 (ru) |
| IL (2) | IL165322A0 (ru) |
| MX (1) | MXPA04011820A (ru) |
| MY (1) | MY140953A (ru) |
| NO (1) | NO333939B1 (ru) |
| PL (1) | PL207269B1 (ru) |
| PT (1) | PT1513500E (ru) |
| RU (1) | RU2380091C2 (ru) |
| SI (1) | SI1513500T1 (ru) |
| TW (1) | TWI333422B (ru) |
| UA (1) | UA84270C2 (ru) |
| WO (1) | WO2003101422A2 (ru) |
| ZA (1) | ZA200409616B (ru) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004001558A1 (de) * | 2004-01-10 | 2005-08-18 | Bayer Healthcare Ag | Arzneimittel zur topischen Applikation bei Tieren |
| EP1830851A2 (en) * | 2004-12-06 | 2007-09-12 | Themis Laboratories Private Limited | Rapid disintegrating taste masked compositions and a process for its preparations |
| DE102005025900A1 (de) * | 2005-06-06 | 2006-12-07 | Basf Ag | Verfahren zur Entfernung von Salzen aus einem Alkoxycarbonylaminotriazin enthaltenden Reaktionsgemisch |
| US20080051332A1 (en) * | 2005-11-18 | 2008-02-28 | Nastech Pharmaceutical Company Inc. | Method of modulating hematopoietic stem cells and treating hematologic diseases using intranasal parathyroid hormone |
| CN100360131C (zh) * | 2006-01-24 | 2008-01-09 | 新昌国邦化学工业有限公司 | 一种掩味恩诺沙星的生产方法 |
| US20070248564A1 (en) * | 2006-04-25 | 2007-10-25 | Roxane Laboratories, Inc. | Formulation of sodium polystyrene sulfonate suspension for the treatment of hyperkalemia |
| CA2661576A1 (en) * | 2006-09-26 | 2008-04-03 | Taro Pharmaceuticals North America, Inc. | Stabilizing compositions for antibiotics and methods of use |
| DE102006049520A1 (de) | 2006-10-20 | 2008-04-24 | Bayer Healthcare Ag | Verfahren zur Herstellung von Pradofloxacin |
| US20080118570A1 (en) * | 2006-11-20 | 2008-05-22 | Zhi Liu | Polymer coated drug-ion exchange resins and methods |
| CA2719246A1 (en) * | 2008-03-26 | 2009-10-01 | Taro Pharmaceuticals North America, Inc. | Stabilizing lipid compositions for oral pharmaceutical agents |
| PL2544532T3 (pl) | 2010-03-12 | 2017-08-31 | Monsanto Technology Llc | Agrochemiczne kompozycje żelowe |
| PT2572717T (pt) * | 2010-05-19 | 2016-07-19 | Astellas Pharma Inc | Composição farmacêutica contendo solifenacina |
| BR112014009547A8 (pt) | 2011-10-19 | 2018-01-23 | Scherer Technologies Llc R P | composição farmacêutica para administração oral, e, sistema de liberação para a administração oral de uma composição farmacêutica bifásica |
| FR2998305B1 (fr) * | 2012-11-22 | 2015-02-20 | Henkel Ag & Co Kgaa | Substances actives contenant des groupes sulfonates ameliorant la puissance de lavage primaire |
| KR101697095B1 (ko) * | 2015-09-30 | 2017-01-18 | 주식회사 포스코 | 더스트 막힘을 방지할 수 있는 배가스 청정 라인의 실탱크 |
| DK3784656T3 (da) | 2018-04-25 | 2023-09-18 | Elanco Animal Health Gmbh | Fremgangsmåde til hydrolyse af quinoloncarboxylestere |
| CN114249749B (zh) * | 2022-01-08 | 2024-03-22 | 天象生物药业邢台有限责任公司 | 一种马波沙星甲酸盐的转化方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60204713A (ja) | 1984-03-30 | 1985-10-16 | Zenyaku Kogyo Kk | 水性懸濁組成物 |
| GB8618847D0 (en) * | 1986-08-01 | 1986-09-10 | Smith Kline French Lab | Pharmaceutical formulations |
| DE3719764A1 (de) * | 1987-06-13 | 1988-12-22 | Bayer Ag | Ionenaustauscherharze beladen mit chinoloncarbonsaeurederivaten, ihre herstellung und verwendung |
| US5338732A (en) * | 1991-06-18 | 1994-08-16 | Bristol-Myers Squibb Company | Megestrol acetate formulation |
| JP3311350B2 (ja) * | 1991-10-28 | 2002-08-05 | ザ、プロクター、エンド、ギャンブル、カンパニー | 飲料増粘剤／乳化剤系 |
| JP3207494B2 (ja) * | 1992-04-02 | 2001-09-10 | ロート製薬株式会社 | 水性懸濁製剤 |
| DE4319649A1 (de) * | 1993-03-18 | 1994-09-22 | Asta Medica Ag | Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe |
| PT882049E (pt) * | 1996-02-23 | 2003-04-30 | Bayer Ag | Acidos 8-ciano-1-ciclopropil-7-(2,8-diazabiciclo-¬4.3.0|nonan-8-il)-6-fluoro-1,4-dihidro-4-oxo-quinolino-carboxilicos eventualmente substituidos e seus derivados |
| US5980882A (en) * | 1997-04-16 | 1999-11-09 | Medeva Pharmaceuticals Manufacturing | Drug-resin complexes stabilized by chelating agents |
| DE19854357A1 (de) * | 1998-11-25 | 2000-05-31 | Bayer Ag | Semi-Hydrochlorid von 8-Cyan-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo/4.3.0/ -nonan-8-yl)-6-fluor-1,4-dihydro-4-oxo-3-chinolincarbonsäure |
| WO2001005431A1 (en) | 1999-07-14 | 2001-01-25 | Schering-Plough Ltd. | Taste masking of oral quinolone liquid preparations using ion exchange resins |
| GB9930058D0 (en) * | 1999-12-20 | 2000-02-09 | Novartis Ag | Organic compounds |
| GB0020089D0 (en) | 2000-08-15 | 2000-10-04 | Smithkline Beecham Biolog | Vaccine Composition |
| DE10134719A1 (de) | 2001-07-17 | 2003-02-06 | Bayer Ag | Pharmazeutische Zubereitungen enthaltend wirkstoffbeladene Ionentauscherharze |
| US7001667B2 (en) * | 2002-07-17 | 2006-02-21 | Ppg Industries Ohio, Inc. | Alkyd-based free radical wood coating compositions |
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2002
- 2002-05-31 DE DE10224086A patent/DE10224086A1/de not_active Withdrawn
-
2003
- 2003-05-19 WO PCT/EP2003/005228 patent/WO2003101422A2/de active Application Filing
- 2003-05-19 RU RU2004139022/15A patent/RU2380091C2/ru active
- 2003-05-19 BR BR0311511-9A patent/BR0311511A/pt active IP Right Grant
- 2003-05-19 US US10/516,344 patent/US8545829B2/en not_active Expired - Lifetime
- 2003-05-19 AU AU2003242545A patent/AU2003242545B2/en not_active Expired
- 2003-05-19 BR BRPI0311511-9A patent/BRPI0311511B1/pt unknown
- 2003-05-19 DE DE50311123T patent/DE50311123D1/de not_active Expired - Lifetime
- 2003-05-19 KR KR10-2004-7019371A patent/KR20050010015A/ko not_active Application Discontinuation
- 2003-05-19 PT PT03755931T patent/PT1513500E/pt unknown
- 2003-05-19 UA UA20041210942A patent/UA84270C2/ru unknown
- 2003-05-19 EP EP03755931A patent/EP1513500B1/de not_active Expired - Lifetime
- 2003-05-19 MX MXPA04011820A patent/MXPA04011820A/es active IP Right Grant
- 2003-05-19 DK DK03755931T patent/DK1513500T3/da active
- 2003-05-19 KR KR1020127026888A patent/KR20120123607A/ko not_active Application Discontinuation
- 2003-05-19 IL IL16532203A patent/IL165322A0/xx unknown
- 2003-05-19 SI SI200331534T patent/SI1513500T1/sl unknown
- 2003-05-19 KR KR1020117031524A patent/KR101258373B1/ko active IP Right Grant
- 2003-05-19 ES ES03755931T patent/ES2319115T3/es not_active Expired - Lifetime
- 2003-05-19 JP JP2004508780A patent/JP5350574B2/ja not_active Expired - Lifetime
- 2003-05-19 AT AT03755931T patent/ATE421317T1/de active
- 2003-05-19 CN CN038182106A patent/CN1671361B/zh not_active Expired - Lifetime
- 2003-05-19 CA CA2487648A patent/CA2487648C/en not_active Expired - Lifetime
- 2003-05-19 PL PL373456A patent/PL207269B1/pl unknown
- 2003-05-28 AR ARP030101867A patent/AR039861A1/es not_active Application Discontinuation
- 2003-05-29 MY MYPI20031984A patent/MY140953A/en unknown
- 2003-05-30 TW TW092114643A patent/TWI333422B/zh not_active IP Right Cessation
-
2004
- 2004-11-22 IL IL165322A patent/IL165322A/en active IP Right Grant
- 2004-11-24 CR CR7598A patent/CR7598A/es not_active Application Discontinuation
- 2004-11-29 ZA ZA200409616A patent/ZA200409616B/xx unknown
- 2004-12-28 HR HRP20041219AA patent/HRP20041219B1/hr not_active IP Right Cessation
- 2004-12-29 NO NO20045700A patent/NO333939B1/no not_active IP Right Cessation
-
2006
- 2006-03-14 HK HK06103261.0A patent/HK1083200A1/xx not_active IP Right Cessation
-
2010
- 2010-10-20 JP JP2010235021A patent/JP2011012087A/ja not_active Withdrawn
-
2016
- 2016-08-23 AR ARP160102580A patent/AR105798A2/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TZ4A | Amendments of patent specification | ||
| PC41 | Official registration of the transfer of exclusive right |
Effective date: 20130207 |