RO121604B1 - Sistem de expresie pentru factorul viii - Google Patents
Sistem de expresie pentru factorul viii Download PDFInfo
- Publication number
- RO121604B1 RO121604B1 ROA200100649A RO200100649A RO121604B1 RO 121604 B1 RO121604 B1 RO 121604B1 RO A200100649 A ROA200100649 A RO A200100649A RO 200100649 A RO200100649 A RO 200100649A RO 121604 B1 RO121604 B1 RO 121604B1
- Authority
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- Romania
- Prior art keywords
- serum
- lion
- wave
- gly
- thr
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- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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Landscapes
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| US09/209,916 US6358703B1 (en) | 1998-12-10 | 1998-12-10 | Expression system for factor VIII |
| PCT/US1999/029169 WO2000034505A1 (en) | 1998-12-10 | 1999-12-08 | Expression system for factor viii |
Publications (1)
| Publication Number | Publication Date |
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Family Applications (1)
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| ROA200100649A RO121604B1 (ro) | 1998-12-10 | 1999-12-08 | Sistem de expresie pentru factorul viii |
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| NO (1) | NO329544B1 (enExample) |
| NZ (1) | NZ512234A (enExample) |
| PL (1) | PL200676B1 (enExample) |
| PT (1) | PT1137797E (enExample) |
| RO (1) | RO121604B1 (enExample) |
| RU (1) | RU2249041C2 (enExample) |
| SI (1) | SI20644B (enExample) |
| SK (1) | SK286945B6 (enExample) |
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| TWI423986B (zh) | 2005-12-20 | 2014-01-21 | 必治妥美雅史谷比公司 | 組合物及製造組合物之方法 |
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| PL2235197T3 (pl) | 2007-12-27 | 2018-01-31 | Baxalta GmbH | Sposoby hodowli komórek |
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| CA2728708A1 (en) * | 2008-06-25 | 2009-12-30 | Bayer Healthcare Llc | Factor viii muteins with reduced immunogenicity |
| AU2009284113B2 (en) | 2008-08-21 | 2015-05-14 | Octapharma Ag | Recombinantly produced human factor VIII and IX |
| KR101691443B1 (ko) * | 2008-09-03 | 2016-12-30 | 옥타파마 아게 | 재조합에 의해 제조된 인자 ⅷ을 위한 신규한 보호 조성물 |
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| CN102427823A (zh) * | 2009-03-24 | 2012-04-25 | 拜耳医药保健有限公司 | 因子viii变体及使用方法 |
| BR112012004094A2 (pt) | 2009-08-24 | 2016-03-08 | Amunix Operating Inc | composições de fator vii de coagulação e métodos para fazer e usar as mesmas |
| US20110150843A1 (en) * | 2009-10-30 | 2011-06-23 | National Institute Of Immunology | Method for the therapeutic correction of hemophilia a by transplanting bone marrow cells |
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| KR101980164B1 (ko) * | 2011-05-13 | 2019-05-20 | 옥타파마 아게 | 재조합 ｆｖｉｉｉ의 생산에서 진핵 세포의 생산성을 증가시키는 방법 |
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| LT2822577T (lt) | 2012-02-15 | 2019-03-25 | Bioverativ Therapeutics Inc. | Rekombinantiniai faktoriaus viii baltymai |
| HRP20221531T1 (hr) * | 2012-02-15 | 2023-02-17 | Bioverativ Therapeutics Inc. | Pripravci faktora viii i postupci dobivanja i korištenja istih |
| EP3033097B1 (en) | 2013-08-14 | 2021-03-10 | Bioverativ Therapeutics Inc. | Factor viii-xten fusions and uses thereof |
| DK3091997T5 (da) | 2014-01-10 | 2024-10-14 | Bioverativ Therapeutics Inc | Kimære faktor viii-proteiner og anvendelser deraf |
| MX2018001497A (es) | 2015-08-03 | 2018-05-15 | Bioverativ Therapeutics Inc | Proteinas de fusion de factor ix y metodos para producirlas y usarlas. |
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| RS66972B1 (sr) | 2018-05-18 | 2025-07-31 | Bioverativ Therapeutics Inc | Metode lečenja hemofilije a |
| CA3115535A1 (en) * | 2018-10-23 | 2020-04-30 | The Children's Hospital Of Philadelphia | Compositions and methods for modulating factor viii function |
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-
1998
- 1998-12-10 US US09/209,916 patent/US6358703B1/en not_active Expired - Lifetime
-
1999
- 1999-08-12 UA UA2001074777A patent/UA77383C2/uk unknown
- 1999-12-08 DK DK99966068T patent/DK1137797T3/da active
- 1999-12-08 TR TR2001/01592T patent/TR200101592T2/xx unknown
- 1999-12-08 CZ CZ20012024A patent/CZ302330B6/cs not_active IP Right Cessation
- 1999-12-08 AU AU21701/00A patent/AU761801B2/en not_active Expired
- 1999-12-08 EP EP99966068A patent/EP1137797B1/en not_active Expired - Lifetime
- 1999-12-08 SI SI9920097A patent/SI20644B/sl active Search and Examination
- 1999-12-08 RU RU2001119156/13A patent/RU2249041C2/ru active
- 1999-12-08 NZ NZ512234A patent/NZ512234A/xx not_active IP Right Cessation
- 1999-12-08 BR BRPI9916069A patent/BRPI9916069B8/pt not_active IP Right Cessation
- 1999-12-08 CA CA002354845A patent/CA2354845C/en not_active Expired - Lifetime
- 1999-12-08 DE DE69939839T patent/DE69939839D1/de not_active Expired - Lifetime
- 1999-12-08 PT PT99966068T patent/PT1137797E/pt unknown
- 1999-12-08 SK SK792-2001A patent/SK286945B6/sk not_active IP Right Cessation
- 1999-12-08 RO ROA200100649A patent/RO121604B1/ro unknown
- 1999-12-08 PL PL349284A patent/PL200676B1/pl unknown
- 1999-12-08 HU HU0200558A patent/HU228489B1/hu unknown
- 1999-12-08 AT AT99966068T patent/ATE412765T1/de active
- 1999-12-08 WO PCT/US1999/029169 patent/WO2000034505A1/en not_active Ceased
- 1999-12-08 JP JP2000586938A patent/JP4240818B2/ja not_active Expired - Lifetime
- 1999-12-08 IL IL14335399A patent/IL143353A0/xx unknown
- 1999-12-08 KR KR1020017007149A patent/KR100616028B1/ko not_active Expired - Lifetime
- 1999-12-08 ES ES99966068T patent/ES2315026T3/es not_active Expired - Lifetime
-
2001
- 2001-05-24 IL IL143353A patent/IL143353A/en not_active IP Right Cessation
- 2001-06-01 NO NO20012718A patent/NO329544B1/no not_active IP Right Cessation
- 2001-06-06 BG BG105567A patent/BG65431B1/bg unknown
- 2001-12-06 US US10/006,091 patent/US20020102730A1/en not_active Abandoned
-
2002
- 2002-01-15 US US10/047,257 patent/US20020115152A1/en not_active Abandoned
- 2002-08-22 US US10/225,900 patent/US7459525B2/en not_active Expired - Fee Related
-
2007
- 2007-04-25 US US11/789,580 patent/US20090036358A1/en not_active Abandoned
-
2010
- 2010-11-08 US US12/941,685 patent/US8207117B2/en not_active Expired - Fee Related
-
2012
- 2012-05-29 US US13/482,326 patent/US8945869B2/en not_active Expired - Fee Related
-
2013
- 2013-06-14 US US13/918,053 patent/US9249209B2/en not_active Expired - Fee Related
-
2015
- 2015-12-30 US US14/985,134 patent/US9650431B2/en not_active Expired - Fee Related
-
2017
- 2017-04-05 US US15/480,162 patent/US20170267745A1/en not_active Abandoned
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