CZ302330B6 - Zpusob výroby a izolace proteinu, který má prokoagulacní aktivitu faktoru VIII a bunecná linie - Google Patents
Zpusob výroby a izolace proteinu, který má prokoagulacní aktivitu faktoru VIII a bunecná linie Download PDFInfo
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- CZ302330B6 CZ302330B6 CZ20012024A CZ20012024A CZ302330B6 CZ 302330 B6 CZ302330 B6 CZ 302330B6 CZ 20012024 A CZ20012024 A CZ 20012024A CZ 20012024 A CZ20012024 A CZ 20012024A CZ 302330 B6 CZ302330 B6 CZ 302330B6
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- Prior art keywords
- leu
- protein
- ser
- glu
- thr
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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Landscapes
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| US6475725B1 (en) | 1997-06-20 | 2002-11-05 | Baxter Aktiengesellschaft | Recombinant cell clones having increased stability and methods of making and using the same |
| US6180108B1 (en) * | 1998-12-10 | 2001-01-30 | Bayer Corporation | Vectors having terminal repeat sequence of Epstein-Barr virus |
| US6358703B1 (en) * | 1998-12-10 | 2002-03-19 | Bayer Corporation | Expression system for factor VIII |
| EP1460131A3 (en) * | 2000-03-22 | 2005-06-01 | Octagene GmbH | Production of recombinant blood clotting factors in human cell lines |
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