PT97832B - Processo para a preparacao de membranas biocompativeis perfuradas e de pele artificial - Google Patents
Processo para a preparacao de membranas biocompativeis perfuradas e de pele artificial Download PDFInfo
- Publication number
- PT97832B PT97832B PT97832A PT9783291A PT97832B PT 97832 B PT97832 B PT 97832B PT 97832 A PT97832 A PT 97832A PT 9783291 A PT9783291 A PT 9783291A PT 97832 B PT97832 B PT 97832B
- Authority
- PT
- Portugal
- Prior art keywords
- synthetic
- natural
- process according
- semi
- holes
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title claims abstract description 36
- 238000000034 method Methods 0.000 title claims description 38
- 238000002360 preparation method Methods 0.000 title claims description 6
- 239000000463 material Substances 0.000 claims abstract description 17
- 210000002919 epithelial cell Anatomy 0.000 claims abstract description 14
- 238000000338 in vitro Methods 0.000 claims abstract description 13
- 230000005855 radiation Effects 0.000 claims abstract 2
- 210000002510 keratinocyte Anatomy 0.000 claims description 15
- 210000003491 skin Anatomy 0.000 claims description 15
- 102000008186 Collagen Human genes 0.000 claims description 11
- 108010035532 Collagen Proteins 0.000 claims description 11
- 229920001436 collagen Polymers 0.000 claims description 11
- -1 gelane Polymers 0.000 claims description 10
- 235000010443 alginic acid Nutrition 0.000 claims description 7
- 229920000615 alginic acid Polymers 0.000 claims description 7
- 239000000560 biocompatible material Substances 0.000 claims description 7
- 229920001277 pectin Polymers 0.000 claims description 7
- 229920001817 Agar Polymers 0.000 claims description 6
- 229920000936 Agarose Polymers 0.000 claims description 6
- 229920002101 Chitin Polymers 0.000 claims description 6
- 229920001661 Chitosan Polymers 0.000 claims description 6
- 239000008272 agar Substances 0.000 claims description 6
- 239000001913 cellulose Substances 0.000 claims description 6
- 229920002678 cellulose Polymers 0.000 claims description 6
- 235000010980 cellulose Nutrition 0.000 claims description 6
- 229920002674 hyaluronan Polymers 0.000 claims description 6
- 229960003160 hyaluronic acid Drugs 0.000 claims description 6
- 239000001814 pectin Substances 0.000 claims description 6
- 235000010987 pectin Nutrition 0.000 claims description 6
- 229920001285 xanthan gum Polymers 0.000 claims description 6
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 5
- 229920002683 Glycosaminoglycan Polymers 0.000 claims description 5
- 229920002472 Starch Polymers 0.000 claims description 5
- 239000000783 alginic acid Substances 0.000 claims description 5
- 229960001126 alginic acid Drugs 0.000 claims description 5
- 150000004781 alginic acids Chemical class 0.000 claims description 5
- 230000032050 esterification Effects 0.000 claims description 5
- 238000005886 esterification reaction Methods 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 claims description 5
- 235000019698 starch Nutrition 0.000 claims description 5
- 244000043261 Hevea brasiliensis Species 0.000 claims description 4
- 238000005553 drilling Methods 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 4
- 229920003052 natural elastomer Polymers 0.000 claims description 4
- 229920001194 natural rubber Polymers 0.000 claims description 4
- GJCOSYZMQJWQCA-UHFFFAOYSA-N 9H-xanthene Chemical compound C1=CC=C2CC3=CC=CC=C3OC2=C1 GJCOSYZMQJWQCA-UHFFFAOYSA-N 0.000 claims description 3
- 229920000954 Polyglycolide Polymers 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 3
- 229920001577 copolymer Polymers 0.000 claims description 3
- 239000003431 cross linking reagent Substances 0.000 claims description 3
- 150000004985 diamines Chemical class 0.000 claims description 3
- 229920001971 elastomer Polymers 0.000 claims description 3
- 150000004820 halides Chemical class 0.000 claims description 3
- 229920005615 natural polymer Polymers 0.000 claims description 3
- 229920000747 poly(lactic acid) Polymers 0.000 claims description 3
- 229920002463 poly(p-dioxanone) polymer Polymers 0.000 claims description 3
- 229920002627 poly(phosphazenes) Polymers 0.000 claims description 3
- 229920002492 poly(sulfone) Polymers 0.000 claims description 3
- 229920000447 polyanionic polymer Polymers 0.000 claims description 3
- 239000000622 polydioxanone Substances 0.000 claims description 3
- 239000004633 polyglycolic acid Substances 0.000 claims description 3
- 239000004626 polylactic acid Substances 0.000 claims description 3
- 229920001282 polysaccharide Polymers 0.000 claims description 3
- 239000005017 polysaccharide Substances 0.000 claims description 3
- 150000004804 polysaccharides Chemical class 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 239000002243 precursor Substances 0.000 claims description 3
- 230000035755 proliferation Effects 0.000 claims description 3
- 239000005060 rubber Substances 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 2
- 238000001556 precipitation Methods 0.000 claims description 2
- 229920002230 Pectic acid Polymers 0.000 claims 4
- 150000001991 dicarboxylic acids Chemical class 0.000 claims 2
- 239000003349 gelling agent Substances 0.000 claims 2
- 229940032147 starch Drugs 0.000 claims 2
- 235000015243 ice cream Nutrition 0.000 claims 1
- 230000001376 precipitating effect Effects 0.000 claims 1
- 238000011161 development Methods 0.000 description 11
- 239000002253 acid Substances 0.000 description 9
- 210000004027 cell Anatomy 0.000 description 9
- 238000001356 surgical procedure Methods 0.000 description 5
- 239000001963 growth medium Substances 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 238000002054 transplantation Methods 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 150000007513 acids Chemical class 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 238000004113 cell culture Methods 0.000 description 3
- 230000006378 damage Effects 0.000 description 3
- 210000002615 epidermis Anatomy 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 210000002950 fibroblast Anatomy 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 241000282412 Homo Species 0.000 description 2
- 239000012620 biological material Substances 0.000 description 2
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- 230000001575 pathological effect Effects 0.000 description 2
- 230000000472 traumatic effect Effects 0.000 description 2
- 241000272522 Anas Species 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 description 1
- 206010052779 Transplant rejections Diseases 0.000 description 1
- 102000004142 Trypsin Human genes 0.000 description 1
- 108090000631 Trypsin Proteins 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 150000001299 aldehydes Chemical class 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 230000000890 antigenic effect Effects 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 229960005188 collagen Drugs 0.000 description 1
- 238000002316 cosmetic surgery Methods 0.000 description 1
- 238000005138 cryopreservation Methods 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 230000002055 immunohistochemical effect Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000011278 mitosis Effects 0.000 description 1
- 235000019271 petrolatum Nutrition 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 229910000077 silane Inorganic materials 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 229910021653 sulphate ion Inorganic materials 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
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- 238000012360 testing method Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
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- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0625—Epidermal cells, skin cells; Cells of the oral mucosa
- C12N5/0629—Keratinocytes; Whole skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/10—Hair or skin implants
- A61F2/105—Skin implants, e.g. artificial skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0062—General methods for three-dimensional culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/80—Hyaluronan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2539/00—Supports and/or coatings for cell culture characterised by properties
- C12N2539/10—Coating allowing for selective detachment of cells, e.g. thermoreactive coating
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24273—Structurally defined web or sheet [e.g., overall dimension, etc.] including aperture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Transplantation (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02051390A IT1248934B (it) | 1990-06-01 | 1990-06-01 | Membrane forate biocompatibili,processi per la loro preparazione,loro impiego come supporto per la crescita in vitro di cellule epiteliali, pelli artificiali cosi' ottenute e loro impiego nei trapianti di pelle |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT97832A PT97832A (pt) | 1992-02-28 |
| PT97832B true PT97832B (pt) | 1998-10-30 |
Family
ID=11168072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT97832A PT97832B (pt) | 1990-06-01 | 1991-05-31 | Processo para a preparacao de membranas biocompativeis perfuradas e de pele artificial |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US5326356A (en, 2012) |
| EP (1) | EP0462426B1 (en, 2012) |
| JP (1) | JP3202257B2 (en, 2012) |
| KR (1) | KR100195574B1 (en, 2012) |
| AR (1) | AR244354A1 (en, 2012) |
| AT (1) | ATE156689T1 (en, 2012) |
| AU (1) | AU637235B2 (en, 2012) |
| BR (1) | BR9102225A (en, 2012) |
| CA (1) | CA2043527C (en, 2012) |
| DE (1) | DE69127235T2 (en, 2012) |
| DK (1) | DK0462426T3 (en, 2012) |
| ES (1) | ES2108019T3 (en, 2012) |
| FI (1) | FI108918B (en, 2012) |
| GR (1) | GR3025075T3 (en, 2012) |
| HU (1) | HU215534B (en, 2012) |
| IE (1) | IE911825A1 (en, 2012) |
| IL (1) | IL98255A (en, 2012) |
| IT (1) | IT1248934B (en, 2012) |
| NO (1) | NO303562B1 (en, 2012) |
| PT (1) | PT97832B (en, 2012) |
| SG (1) | SG52545A1 (en, 2012) |
| TW (1) | TW208652B (en, 2012) |
| UY (1) | UY23231A1 (en, 2012) |
| ZA (1) | ZA914098B (en, 2012) |
Families Citing this family (165)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10237531A1 (de) | 2002-08-16 | 2004-02-26 | Tutogen Medical Gmbh | Implantat |
| US6033437A (en) | 1991-09-30 | 2000-03-07 | Orbital Implant Technology | Pegs for orbital implants |
| IT1263144B (it) * | 1993-02-04 | 1996-08-01 | Lanfranco Callegaro | Composizioni farmaceutiche comprendenti materiale spugnoso costituito da derivati esterei dell'acido ialuronico in associazione con altre sostanze farmacologicamente attive |
| IT1263316B (it) * | 1993-02-12 | 1996-08-05 | Fidia Advanced Biopolymers Srl | Tessuto non tessuto multistrato in cui uno degli strati e' costituito essenzialmente da esteri dell'acido ialuronico |
| US6176874B1 (en) * | 1993-10-18 | 2001-01-23 | Masschusetts Institute Of Technology | Vascularized tissue regeneration matrices formed by solid free form fabrication techniques |
| USD362120S (en) | 1994-03-16 | 1995-09-12 | Confab, Inc. | Apertured coverstock for absorbent articles |
| DE4426315C1 (de) * | 1994-07-25 | 1996-03-21 | Gore W L & Ass Gmbh | Membran zur Regeneration von Körpergeweben und Verwendung der Membran als Wundabdeckung und Hautersatz |
| US6294202B1 (en) * | 1994-10-06 | 2001-09-25 | Genzyme Corporation | Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers |
| JP3543869B2 (ja) * | 1995-03-07 | 2004-07-21 | 株式会社メニコン | 培養皮膚およびその製造法 |
| IT1281870B1 (it) * | 1995-04-27 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Pelle artificiale umana costituita da materiali biocompatibili a base di derivati dell'acido ialuronico |
| US20040002772A1 (en) * | 1995-04-28 | 2004-01-01 | Organogenesis, Inc. | Tissue equivalents with perforations for improved integration to host tissues and methods for producing perforated tissue equivalents |
| GB9512529D0 (en) * | 1995-06-20 | 1995-08-23 | Bnfl Fluorchem Ltd | Cell treatment |
| US5693332C1 (en) * | 1995-08-11 | 2001-01-09 | Univ California | Human keratinocytes supported on a hydrophilic membrane and methods of using same to effect wound closure |
| AU6775596A (en) * | 1995-08-16 | 1997-03-12 | Integra Lifesciences Corporation | Perforated artificial skin grafts |
| BR9610996A (pt) * | 1995-08-29 | 1999-07-13 | Fidia Advanced Biopolymers Srl | Biomateriais para prevenção de ades es pós-cirúrgicas compreendendo derivados de ácidos hialurônico |
| IT1282207B1 (it) * | 1995-11-20 | 1998-03-16 | Fidia Advanced Biopolymers Srl | Sistemi di coltura di cellule staminali di midollo osseo umano in matrici tridimensionali costituiti da esteri dell'acido ialuronico |
| WO1997045532A1 (en) * | 1996-05-28 | 1997-12-04 | Brown University Research Foundation | Hyaluronan based biodegradable scaffolds for tissue repair |
| US5919234A (en) | 1996-08-19 | 1999-07-06 | Macropore, Inc. | Resorbable, macro-porous, non-collapsing and flexible membrane barrier for skeletal repair and regeneration |
| US6306491B1 (en) | 1996-12-20 | 2001-10-23 | Gore Enterprise Holdings, Inc. | Respiratory aids |
| US20050033132A1 (en) | 1997-03-04 | 2005-02-10 | Shults Mark C. | Analyte measuring device |
| US7192450B2 (en) | 2003-05-21 | 2007-03-20 | Dexcom, Inc. | Porous membranes for use with implantable devices |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US6741877B1 (en) | 1997-03-04 | 2004-05-25 | Dexcom, Inc. | Device and method for determining analyte levels |
| TW586934B (en) * | 1997-05-19 | 2004-05-11 | Sumitomo Pharma | Immunopotentiating composition |
| ES2132027B1 (es) * | 1997-07-04 | 2000-04-01 | Comunitario De Transfusion Del | Desarrollo de una piel artificial mediante cultivo de queratinocitos sobre una base de fibrina y fibroblastos humanos y metodo de preparacion de esta piel para trasplante. |
| US6063117A (en) * | 1998-01-22 | 2000-05-16 | Perry; Arthur C. | Porous orbital implant structure |
| JP2003517326A (ja) * | 1998-01-23 | 2003-05-27 | マーコポーア インコーポレイテッド | 骨修復および再生のための再吸収性で、マクロ多孔性で、非崩壊性で且つ可撓性の膜バリア |
| ATE286692T1 (de) | 1998-04-07 | 2005-01-15 | Macropore Inc | Membran mit gewellter oberfläche zur führung des gewebes |
| US6175752B1 (en) | 1998-04-30 | 2001-01-16 | Therasense, Inc. | Analyte monitoring device and methods of use |
| US8974386B2 (en) | 1998-04-30 | 2015-03-10 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US9066695B2 (en) | 1998-04-30 | 2015-06-30 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8480580B2 (en) | 1998-04-30 | 2013-07-09 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US6949816B2 (en) | 2003-04-21 | 2005-09-27 | Motorola, Inc. | Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same |
| US8465425B2 (en) | 1998-04-30 | 2013-06-18 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8688188B2 (en) | 1998-04-30 | 2014-04-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| US8346337B2 (en) | 1998-04-30 | 2013-01-01 | Abbott Diabetes Care Inc. | Analyte monitoring device and methods of use |
| ITPD980149A1 (it) | 1998-06-17 | 1999-12-17 | Fidia Advanced Biopolymers Srl | Protesi tridimensionali comprendenti derivati dell'acido ialuronico per riparare o ricostruire i tessuti danneggiati e processo per la |
| US5976150A (en) * | 1998-08-25 | 1999-11-02 | Alcon Laboratories, Inc. | Intraocular lens injection system |
| US6278079B1 (en) | 1999-02-09 | 2001-08-21 | Edwards Lifesciences Corp. | Laser cutting of fabric grafts |
| FR2792650B1 (fr) | 1999-04-20 | 2003-02-28 | Oreal | Equivalent de peau agee, son procede de preparation et son utilisation |
| WO2000066055A1 (fr) * | 1999-04-30 | 2000-11-09 | Boris Alexeevich Paramonov | Bandage |
| DE19922078A1 (de) * | 1999-05-15 | 2000-11-23 | Weitzel Kage Doris | Gewebekonstrukt für die Transplantationschirurgie |
| IT1306679B1 (it) * | 1999-06-29 | 2001-10-02 | Fidia Advanced Biopolymers Srl | Uso dei derivati dell'acido ialuronico per la preparazione dicomposizoni farmaceutiche e biomateriali per la prevenzione della |
| US6733530B1 (en) * | 1999-08-02 | 2004-05-11 | Eric Sun-Yin Chan | Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin |
| NZ527874A (en) * | 1999-12-03 | 2005-04-29 | Univ Leeds | Replacement kit for repair of damaged tissue on the surface of bones |
| DE19959750C1 (de) * | 1999-12-11 | 2001-05-31 | Axel Thierauf | Verfahren zur Herstellung eines Hautimplantats, insbesondere Eigenhaut-Implantat und nach dem Verfahren hergestelltes Implantat |
| US6560471B1 (en) | 2001-01-02 | 2003-05-06 | Therasense, Inc. | Analyte monitoring device and methods of use |
| PT1404809E (pt) * | 2001-03-02 | 2014-03-20 | Stratatech Corp | Substitutos de pele melhorados e suas utilizações |
| US6974697B2 (en) * | 2001-03-02 | 2005-12-13 | Stratech Corporation | Skin substitutes with improved barrier function |
| EP1397068A2 (en) | 2001-04-02 | 2004-03-17 | Therasense, Inc. | Blood glucose tracking apparatus and methods |
| DE10135676A1 (de) * | 2001-07-21 | 2003-02-06 | Degussa Bioactives Deutschland | Physiologisch verträglicher, Cellulose enthaltender Film |
| US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US6702857B2 (en) | 2001-07-27 | 2004-03-09 | Dexcom, Inc. | Membrane for use with implantable devices |
| DE10151296A1 (de) | 2001-10-17 | 2003-04-30 | Boehringer Ingelheim Pharma | Keratinozyten verwendbar als biologisch aktive Substanz bei der Behandlung von Wunden |
| KR20030032420A (ko) * | 2001-10-18 | 2003-04-26 | 한국과학기술연구원 | 손상된 안구 조직의 재생을 위한 생분해성 고분자로제조된 다공성 지지체 |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US8260393B2 (en) | 2003-07-25 | 2012-09-04 | Dexcom, Inc. | Systems and methods for replacing signal data artifacts in a glucose sensor data stream |
| US9247901B2 (en) | 2003-08-22 | 2016-02-02 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US8010174B2 (en) | 2003-08-22 | 2011-08-30 | Dexcom, Inc. | Systems and methods for replacing signal artifacts in a glucose sensor data stream |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| ATE465242T1 (de) * | 2002-04-30 | 2010-05-15 | Stratatech Corp | Exogene angiogene wachstumsfaktoren exprimierende keratinozyten |
| US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
| AU2003249310A1 (en) * | 2002-07-17 | 2004-02-02 | Proxy Biomedical Limited | Soft tissue implants and methods for making same |
| AU2003265103A1 (en) * | 2002-09-30 | 2004-04-19 | Bioland Ltd. | Dermal substitute consisting of amnion and biodegradable polymer, the preparation method and the use thereof |
| US8685943B2 (en) | 2003-03-12 | 2014-04-01 | Hill's Pet Nutrition, Inc. | Methods for reducing diarrhea in a companion animal |
| US7134999B2 (en) | 2003-04-04 | 2006-11-14 | Dexcom, Inc. | Optimized sensor geometry for an implantable glucose sensor |
| US7875293B2 (en) | 2003-05-21 | 2011-01-25 | Dexcom, Inc. | Biointerface membranes incorporating bioactive agents |
| EP1896092A1 (de) * | 2003-05-24 | 2008-03-12 | JUVENA (International) AG | Kosmetische oder dermatologische Zubereitung umfassend eine Nährmedienphase |
| WO2007120442A2 (en) | 2003-07-25 | 2007-10-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8423113B2 (en) | 2003-07-25 | 2013-04-16 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US7519408B2 (en) | 2003-11-19 | 2009-04-14 | Dexcom, Inc. | Integrated receiver for continuous analyte sensor |
| US8060173B2 (en) | 2003-08-01 | 2011-11-15 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US20190357827A1 (en) | 2003-08-01 | 2019-11-28 | Dexcom, Inc. | Analyte sensor |
| US7774145B2 (en) | 2003-08-01 | 2010-08-10 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20100168543A1 (en) | 2003-08-01 | 2010-07-01 | Dexcom, Inc. | System and methods for processing analyte sensor data |
| US8275437B2 (en) | 2003-08-01 | 2012-09-25 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8845536B2 (en) | 2003-08-01 | 2014-09-30 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8160669B2 (en) | 2003-08-01 | 2012-04-17 | Dexcom, Inc. | Transcutaneous analyte sensor |
| EP3100611B1 (en) * | 2003-08-01 | 2018-09-12 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| JP4863714B2 (ja) | 2003-08-07 | 2012-01-25 | 旭化成クラレメディカル株式会社 | 複合多孔膜とその製造方法 |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20140121989A1 (en) | 2003-08-22 | 2014-05-01 | Dexcom, Inc. | Systems and methods for processing analyte sensor data |
| US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
| US8774886B2 (en) | 2006-10-04 | 2014-07-08 | Dexcom, Inc. | Analyte sensor |
| US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
| EP2239567B1 (en) | 2003-12-05 | 2015-09-02 | DexCom, Inc. | Calibration techniques for a continuous analyte sensor |
| EP2301428B1 (en) | 2003-12-09 | 2016-11-30 | Dexcom, Inc. | Signal processing for continuous analyte sensor |
| US7364592B2 (en) * | 2004-02-12 | 2008-04-29 | Dexcom, Inc. | Biointerface membrane with macro-and micro-architecture |
| WO2009048462A1 (en) | 2007-10-09 | 2009-04-16 | Dexcom, Inc. | Integrated insulin delivery system with continuous glucose sensor |
| US8808228B2 (en) | 2004-02-26 | 2014-08-19 | Dexcom, Inc. | Integrated medicament delivery device for use with continuous analyte sensor |
| US8500751B2 (en) | 2004-03-31 | 2013-08-06 | Merlin Md Pte Ltd | Medical device |
| US8715340B2 (en) | 2004-03-31 | 2014-05-06 | Merlin Md Pte Ltd. | Endovascular device with membrane |
| EP1734897A4 (en) * | 2004-03-31 | 2010-12-22 | Merlin Md Pte Ltd | PROCESS FOR TREATING ANEURYSMS |
| US20050245799A1 (en) * | 2004-05-03 | 2005-11-03 | Dexcom, Inc. | Implantable analyte sensor |
| US8792955B2 (en) | 2004-05-03 | 2014-07-29 | Dexcom, Inc. | Transcutaneous analyte sensor |
| HUP0401054A2 (en) * | 2004-05-26 | 2006-07-28 | Dr Juhasz Zsuzsanna Rethyne | Process for growing of living tissue on living organism |
| US7777092B2 (en) * | 2004-06-30 | 2010-08-17 | Coloplast A/S | Skin plate adhesive product and method for its manufacture |
| US7713574B2 (en) | 2004-07-13 | 2010-05-11 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US8886272B2 (en) | 2004-07-13 | 2014-11-11 | Dexcom, Inc. | Analyte sensor |
| US8452368B2 (en) | 2004-07-13 | 2013-05-28 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7905833B2 (en) | 2004-07-13 | 2011-03-15 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US7783333B2 (en) | 2004-07-13 | 2010-08-24 | Dexcom, Inc. | Transcutaneous medical device with variable stiffness |
| US20060270922A1 (en) | 2004-07-13 | 2006-11-30 | Brauker James H | Analyte sensor |
| US8565848B2 (en) | 2004-07-13 | 2013-10-22 | Dexcom, Inc. | Transcutaneous analyte sensor |
| US20060029633A1 (en) * | 2004-08-03 | 2006-02-09 | Arthrotek, Inc | Biological patch for use in medical procedures |
| US9163076B2 (en) | 2005-03-01 | 2015-10-20 | Stratatech Corporation | Human skin equivalents expressing exogenous polypeptides |
| WO2006101834A1 (en) | 2005-03-17 | 2006-09-28 | Stratatech Corporation | Skin substitutes with improved purity |
| JP4716092B2 (ja) * | 2005-03-31 | 2011-07-06 | オリンパステルモバイオマテリアル株式会社 | タンパク質多孔マトリックスの製造方法 |
| JP2007006987A (ja) * | 2005-06-28 | 2007-01-18 | Hokkaido Univ | 皮膚再生用の細胞シートを作製するための構造体およびその利用 |
| GB0513552D0 (en) | 2005-07-01 | 2005-08-10 | Bristol Myers Squibb Co | Bandage |
| US20070038299A1 (en) * | 2005-08-12 | 2007-02-15 | Arthrotek, Inc | Multilayer microperforated implant |
| US20090216338A1 (en) * | 2005-09-12 | 2009-08-27 | Peter Gingras | Soft tissue implants and methods for making same |
| KR101420988B1 (ko) | 2005-10-13 | 2014-07-17 | 신세스 게엠바하 | 약물-함침 용기 |
| US8361781B2 (en) | 2006-01-24 | 2013-01-29 | Brown University | Cell aggregation and encapsulation device and method |
| US20070185238A1 (en) * | 2006-02-06 | 2007-08-09 | No-Burn Investments, Llc | Paint with mold inhibitor and insecticide |
| EP1991110B1 (en) | 2006-03-09 | 2018-11-07 | DexCom, Inc. | Systems and methods for processing analyte sensor data |
| US20080064937A1 (en) | 2006-06-07 | 2008-03-13 | Abbott Diabetes Care, Inc. | Analyte monitoring system and method |
| WO2008017170A1 (en) * | 2006-08-10 | 2008-02-14 | Ao Technology Ag | Biomedical polymer material for tissue repair and engineering |
| KR20150036810A (ko) * | 2007-03-30 | 2015-04-07 | 고쿠리쓰다이가쿠호진 규슈다이가쿠 | 세포의 입체 구조체의 제조 방법 |
| US20200037874A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| EP2152350A4 (en) | 2007-06-08 | 2013-03-27 | Dexcom Inc | INTEGRATED MEDICATION RELEASE DEVICE WITH CONTINUOUS ANALYTICAL SENSOR |
| DE102007028423A1 (de) * | 2007-06-20 | 2008-12-24 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren und Vorrichtung zur Bildung von Aggregaten biologischer Zellen |
| US20090123766A1 (en) * | 2007-11-13 | 2009-05-14 | G3 Enterprises | Modified barrier layers in liners for container closures, capable of providing varible, controlled oxygen ingress |
| DK2215212T3 (da) | 2007-11-14 | 2017-11-27 | Stratatech Corp | Kold opbevaring af organotypisk dyrkede hudækvivalenter til kliniske anvendelser |
| WO2009105709A1 (en) | 2008-02-21 | 2009-08-27 | Dexcom, Inc. | Systems and methods for processing, transmitting and displaying sensor data |
| US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
| EP2106784B1 (en) * | 2008-04-03 | 2015-04-22 | Rohm and Haas Company | Hair styling composition |
| CN102076365B (zh) * | 2008-06-20 | 2014-07-30 | 泰国研究基金会 | 生产人造皮肤的方法和系统 |
| US9382514B2 (en) | 2008-06-20 | 2016-07-05 | Escape Therapeutics, Inc. | Compositions comprising mesenchymal stem cell-derived fibroblasts |
| TW201010747A (en) * | 2008-09-02 | 2010-03-16 | Univ Nat Taiwan | Porous material duct and method of fabricating the same |
| WO2010052585A2 (en) | 2008-11-07 | 2010-05-14 | Sofradim Production | Composite mesh including a 3d mesh and a non porous film of oxidized cellulose from bacterial cellulose origin |
| CA2741518A1 (en) * | 2008-11-07 | 2010-05-14 | Sofradim Production | Medical device including a bacterial cellulose sheet, perforated or microperforated as a mesh |
| WO2010086754A2 (en) | 2009-01-30 | 2010-08-05 | Beiersdorf Ag | Cosmetic or dermatological preparation comprising collagen, chitosan, glycosylaminoglycan and cell growth promoting peptide and/or cellular complex |
| US8501476B2 (en) * | 2009-10-07 | 2013-08-06 | Brown University | Assays and methods for fusing cell aggregates to form proto-tissues |
| IT1398807B1 (it) * | 2009-10-29 | 2013-03-18 | Marzaro | Metodo di preparazione di un tessuto organico a-cellulare di origine umana o animale per la rivitalizzazione |
| BR112012021267A2 (pt) | 2010-02-23 | 2015-09-22 | Inst Nat Sante Rech Med | métodos para a preparação de melanócitos a partir de células tronco humanas pluripotentes. |
| US20120065741A1 (en) * | 2010-09-13 | 2012-03-15 | Chao-Fu Chang | Guided tissue regeneration membrane |
| US20140080096A1 (en) * | 2010-09-13 | 2014-03-20 | BioEconeer, Inc. | Guided Tissue Regeneration Membrane |
| US20120265036A1 (en) | 2011-04-15 | 2012-10-18 | Dexcom, Inc. | Advanced analyte sensor calibration and error detection |
| US9243278B2 (en) | 2011-09-22 | 2016-01-26 | Brown University | Mechanotransduction by the synergistic action of heterotypic cell interactions |
| US9468680B2 (en) | 2011-09-22 | 2016-10-18 | Brown University | Differential effects of drugs on transport in a multi-layer 3D spheroid model |
| TWI590843B (zh) * | 2011-12-28 | 2017-07-11 | 信迪思有限公司 | 膜及其製造方法 |
| ES2943709T3 (es) | 2012-04-06 | 2023-06-15 | Merlin Md Pte Ltd | Dispositivos para tratar un aneurisma |
| USD702445S1 (en) * | 2012-05-11 | 2014-04-15 | Columbia Sportswear North America, Inc. | Printed cooling material |
| USD696522S1 (en) * | 2012-05-11 | 2013-12-31 | Columbia Sportswear North America, Inc. | Printed cooling material |
| CN102697600A (zh) * | 2012-05-19 | 2012-10-03 | 江苏百得医疗器械有限公司 | 医用可吸收防粘连薄膜 |
| JP2015518843A (ja) | 2012-05-25 | 2015-07-06 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 創傷、例えば、糖尿病性創傷の処置における、ｄｐｐ−４阻害剤と組み合わせてもよい生物活性物質としてのケラチン生成細胞の使用 |
| ES2705043T3 (es) | 2013-03-13 | 2019-03-21 | Stratatech Corp | Criopreservación de sustitutos de piel humana viables |
| KR102249720B1 (ko) | 2013-06-21 | 2021-05-11 | 디퍼이 신테스 프로덕츠, 인코포레이티드 | 필름 및 제조 방법 |
| CN103394122B (zh) * | 2013-08-08 | 2014-10-29 | 中国科学技术大学 | 一种人工皮肤及其制备方法和应用 |
| ITMI20131904A1 (it) * | 2013-11-18 | 2015-05-19 | Antonio Sambusseti | Dispositivo per la ricostruzione di cute |
| WO2015181372A1 (en) | 2014-05-30 | 2015-12-03 | Sofradim Production | Implant comprising oxidized cellulose and method for preparing such an implant |
| USD786509S1 (en) * | 2014-08-28 | 2017-05-09 | 3M Innovative Properties Company | Welding helmet having a button |
| CA3055551A1 (en) | 2017-03-06 | 2018-09-13 | Tei Biosciences, Inc. | Perforated tissue graft |
| US11331022B2 (en) | 2017-10-24 | 2022-05-17 | Dexcom, Inc. | Pre-connected analyte sensors |
| US11943876B2 (en) | 2017-10-24 | 2024-03-26 | Dexcom, Inc. | Pre-connected analyte sensors |
| JP7290302B2 (ja) * | 2018-10-26 | 2023-06-13 | 国立研究開発法人農業・食品産業技術総合研究機構 | ハイドロゲル膜及びその使用 |
| AU2020353695A1 (en) * | 2019-09-27 | 2022-03-31 | Stratatech Corporation | Methods for treating acute wounds and improving outcomes |
| US12059509B1 (en) | 2020-05-05 | 2024-08-13 | Integra Lifesciences Corporation | Method and matrix for tissue regeneration |
| EP4001296A1 (de) | 2020-11-20 | 2022-05-25 | Eberhard Karls Universität Tübingen | Neue zyklische verbindungen, verfahren zu deren herstellung und die verwendung dieser zyklischen verbindungen in kosmetischen zubereitungen |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2671444A (en) * | 1951-12-08 | 1954-03-09 | Jr Benjamin F Pease | Nonmetallic mesh surgical insert for hernia repair |
| NL8001236A (nl) * | 1980-02-29 | 1981-10-01 | Doornes Transmissie Bv | Transmissie, voorzien van een traploos variabele drijfriemoverbrenging. |
| SE444640B (sv) * | 1980-08-28 | 1986-04-28 | Bergentz Sven Erik | I djur eller menniska implanterbar kerlprotes samt sett for dess framstellning |
| US4553272A (en) * | 1981-02-26 | 1985-11-19 | University Of Pittsburgh | Regeneration of living tissues by growth of isolated cells in porous implant and product thereof |
| US4604346A (en) * | 1984-10-09 | 1986-08-05 | Massachusetts Institute Of Technology | Skin-equivalent prepared by the use of punch biopsy |
| EP0183184A1 (en) * | 1984-11-30 | 1986-06-04 | Ppg Industries, Inc. | Method of cultivating cellular biomaterial and glass fibers with cellular biomaterial or biomaterial |
| US4765985A (en) * | 1985-03-05 | 1988-08-23 | Ciba-Geigy Corporation | Devices and methods for treating memory impairment |
| IL75554A (en) * | 1985-06-18 | 1993-01-14 | Yeda Res & Dev | Matrix for cell cultivation in vitro |
| US4851521A (en) * | 1985-07-08 | 1989-07-25 | Fidia, S.P.A. | Esters of hyaluronic acid |
| DE3539270A1 (de) * | 1985-11-06 | 1987-05-07 | Rolf Prof Dr Med Hettich | Folien-spannrahmen fuer mischtransplantat |
| US5032508A (en) * | 1988-09-08 | 1991-07-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| JPS62246371A (ja) * | 1986-04-19 | 1987-10-27 | 株式会社 高研 | 人工皮膚及びその製造方法 |
| DE3878909T2 (de) | 1987-04-28 | 1993-08-19 | Univ California | Vorrichtung und verfahren zur herstellung eines komposithautersatzes. |
| FR2616318A1 (fr) * | 1987-06-15 | 1988-12-16 | Centre Nat Rech Scient | Peau artificielle et son procede de preparation |
| US5015584A (en) * | 1987-10-14 | 1991-05-14 | Board Of Regents, The University Of Texas System | Epidermal graft system |
| US5122470A (en) * | 1988-07-05 | 1992-06-16 | Banes Albert J | Floating cell culture device and method |
| NL8801741A (nl) * | 1988-07-08 | 1990-02-01 | Utermoehlen Nv | Kunsthuid. |
| DE3830481A1 (de) * | 1988-09-08 | 1990-03-22 | Ethicon Gmbh | Schlauchfoermiges implantat, sowie verfahren zu dessen herstellung |
| JPH0662678B2 (ja) * | 1988-11-28 | 1994-08-17 | 電気化学工業株式会社 | ヒアルロン酸固定化蛋白質及びその製造方法 |
| EP0402718B1 (en) * | 1989-06-03 | 1994-11-02 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Control of cell arrangement |
-
1990
- 1990-06-01 IT IT02051390A patent/IT1248934B/it active IP Right Grant
-
1991
- 1991-05-24 IL IL98255A patent/IL98255A/xx not_active IP Right Cessation
- 1991-05-28 IE IE182591A patent/IE911825A1/en not_active IP Right Cessation
- 1991-05-28 DK DK91108654.4T patent/DK0462426T3/da active
- 1991-05-28 SG SG1996005810A patent/SG52545A1/en unknown
- 1991-05-28 AT AT91108654T patent/ATE156689T1/de not_active IP Right Cessation
- 1991-05-28 EP EP91108654A patent/EP0462426B1/en not_active Expired - Lifetime
- 1991-05-28 DE DE69127235T patent/DE69127235T2/de not_active Expired - Lifetime
- 1991-05-28 ES ES91108654T patent/ES2108019T3/es not_active Expired - Lifetime
- 1991-05-29 BR BR919102225A patent/BR9102225A/pt not_active IP Right Cessation
- 1991-05-29 NO NO912058A patent/NO303562B1/no not_active IP Right Cessation
- 1991-05-29 ZA ZA914098A patent/ZA914098B/xx unknown
- 1991-05-30 AU AU78066/91A patent/AU637235B2/en not_active Expired
- 1991-05-30 FI FI912591A patent/FI108918B/fi active
- 1991-05-30 AR AR91319818A patent/AR244354A1/es active
- 1991-05-30 TW TW080104245A patent/TW208652B/zh not_active IP Right Cessation
- 1991-05-30 CA CA002043527A patent/CA2043527C/en not_active Expired - Lifetime
- 1991-05-31 PT PT97832A patent/PT97832B/pt not_active IP Right Cessation
- 1991-05-31 UY UY23231A patent/UY23231A1/es not_active IP Right Cessation
- 1991-05-31 KR KR1019910008999A patent/KR100195574B1/ko not_active Expired - Lifetime
- 1991-05-31 HU HU911834A patent/HU215534B/hu unknown
- 1991-05-31 JP JP12924591A patent/JP3202257B2/ja not_active Expired - Lifetime
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1993
- 1993-02-16 US US08/019,818 patent/US5326356A/en not_active Expired - Lifetime
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1994
- 1994-03-14 US US08/209,626 patent/US5650164A/en not_active Expired - Lifetime
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1995
- 1995-06-07 US US08/478,541 patent/US5658331A/en not_active Expired - Lifetime
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1997
- 1997-10-16 GR GR970402714T patent/GR3025075T3/el unknown
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