PT1404809E - Substitutos de pele melhorados e suas utilizações - Google Patents

Substitutos de pele melhorados e suas utilizações Download PDF

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Publication number
PT1404809E
PT1404809E PT2725028T PT02725028T PT1404809E PT 1404809 E PT1404809 E PT 1404809E PT 2725028 T PT2725028 T PT 2725028T PT 02725028 T PT02725028 T PT 02725028T PT 1404809 E PT1404809 E PT 1404809E
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PT
Portugal
Prior art keywords
improved skin
skin substitutes
substitutes
improved
skin
Prior art date
Application number
PT2725028T
Other languages
English (en)
Inventor
Allen Comer
Lynn Allen-Hoffmann
Michael Hoffmann
Cathy Ann-Rasmussen Ivarie
Paul Barth Conrad
Original Assignee
Stratatech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stratatech Corp filed Critical Stratatech Corp
Publication of PT1404809E publication Critical patent/PT1404809E/pt

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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • C12N5/0698—Skin equivalents
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/09—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells
    • C12N2502/094—Coculture with; Conditioned medium produced by epidermal cells, skin cells, oral mucosa cells keratinocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/04—Screening or testing on artificial tissues
    • C12N2503/06—Screening or testing on artificial skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2510/00—Genetically modified cells
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/148—Screening for cosmetic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
PT2725028T 2001-03-02 2002-03-01 Substitutos de pele melhorados e suas utilizações PT1404809E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27303401P 2001-03-02 2001-03-02
US28789801P 2001-05-01 2001-05-01

Publications (1)

Publication Number Publication Date
PT1404809E true PT1404809E (pt) 2014-03-20

Family

ID=26955894

Family Applications (1)

Application Number Title Priority Date Filing Date
PT2725028T PT1404809E (pt) 2001-03-02 2002-03-01 Substitutos de pele melhorados e suas utilizações

Country Status (11)

Country Link
US (3) US7501238B2 (pt)
EP (1) EP1404809B1 (pt)
JP (2) JP4317366B2 (pt)
AU (3) AU2002255618B2 (pt)
CA (1) CA2439899C (pt)
DK (1) DK1404809T3 (pt)
ES (1) ES2457092T3 (pt)
IL (3) IL157667A0 (pt)
NZ (4) NZ549527A (pt)
PT (1) PT1404809E (pt)
WO (1) WO2002070729A2 (pt)

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JP6817610B2 (ja) * 2016-04-05 2021-01-20 日本メナード化粧品株式会社 三次元培養表皮モデル及びその製造方法、ならびに三次元培養表皮モデルの使用方法
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FR3068045B1 (fr) 2017-06-22 2021-06-04 Expanscience Lab Modeles de peau sensible reconstituee
EP4095235A4 (en) * 2020-01-22 2024-03-06 Aist THREE-DIMENSIONAL CULTURE OF IMMORTALIZED SKIN CELLS HAVING A SURFACE LAYER FORMED OF STRATUM CORNEUM, METHOD FOR PRODUCING SAID THREE-DIMENSIONAL CULTURE, AND METHOD FOR EVALUATING A TEST SUBSTANCE USING SAID THREE-DIMENSIONAL CULTURE
EP4150053A1 (en) * 2020-05-13 2023-03-22 Stratatech Corporation Viable bioengineered skin constructs
JP7041977B2 (ja) * 2020-11-17 2022-03-25 日本メナード化粧品株式会社 三次元培養表皮モデル及びその製造方法、ならびに三次元培養表皮モデルの使用方法
KR102583179B1 (ko) * 2020-11-27 2023-09-26 (주)엑셀세라퓨틱스 칼슘, 상피세포성장인자 및 알부민을 포함하는 각질형성세포 수립 또는 배양용 배지 조성물
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CA2439899C (en) 2015-09-29
US20050226853A1 (en) 2005-10-13
EP1404809B1 (en) 2013-12-11
US7501238B2 (en) 2009-03-10
IL195076A (en) 2012-02-29
IL195076A0 (en) 2011-08-01
CA2439899A1 (en) 2002-09-12
NZ549527A (en) 2008-04-30
AU2010214639A1 (en) 2010-09-16
DK1404809T3 (da) 2014-03-17
AU2006249240B2 (en) 2010-05-27
JP2005505312A (ja) 2005-02-24
AU2006249240A1 (en) 2007-01-04
JP4317366B2 (ja) 2009-08-19
NZ549528A (en) 2008-04-30
JP4989674B2 (ja) 2012-08-01
EP1404809A2 (en) 2004-04-07
US20020187498A1 (en) 2002-12-12
NZ528166A (en) 2007-05-31
US6846675B2 (en) 2005-01-25
US20020164793A1 (en) 2002-11-07
WO2002070729A2 (en) 2002-09-12
ES2457092T3 (es) 2014-04-24
AU2002255618B2 (en) 2006-09-07
AU2010214639B2 (en) 2012-04-19
WO2002070729A3 (en) 2004-01-22
IL157667A0 (en) 2004-03-28
EP1404809A4 (en) 2005-08-10
IL157667A (en) 2009-09-22
NZ549526A (en) 2009-06-26
US7541188B2 (en) 2009-06-02
JP2009195232A (ja) 2009-09-03

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