US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
US7671200B2
(en)
*
|
1999-10-27 |
2010-03-02 |
Cytokinetics, Inc. |
Quinazolinone KSP inhibitors
|
US7230000B1
(en)
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
US6667300B2
(en)
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
US6608053B2
(en)
|
2000-04-27 |
2003-08-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Fused heteroaryl derivatives
|
US6403588B1
(en)
|
2000-04-27 |
2002-06-11 |
Yamanouchi Pharmaceutical Co., Ltd. |
Imidazopyridine derivatives
|
US7829084B2
(en)
*
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
IL149462A0
(en)
*
|
2001-05-09 |
2002-11-10 |
Warner Lambert Co |
Method of treating or inhibiting neutrophil chemotaxis by administering a mek inhibitor
|
US6689782B2
(en)
|
2001-07-16 |
2004-02-10 |
Essential Therapeutics, Inc. |
Fungal efflux pump inhibitors
|
AU2002364889A1
(en)
*
|
2001-09-24 |
2003-06-10 |
University Of Aarhus |
Methods for diagnosis and treatment of diseases associated with altered expression of nrf2
|
EP1442132A2
(en)
*
|
2001-10-26 |
2004-08-04 |
Novartis AG |
Methods for the treatment of osteoarthritis and compositions thereof
|
US7060705B2
(en)
|
2001-11-07 |
2006-06-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
EP1480980A4
(en)
*
|
2002-02-15 |
2005-04-20 |
Cytokinetics Inc |
SYNTHESIS OF QUINAZOLINONES
|
TWI314928B
(en)
*
|
2002-02-28 |
2009-09-21 |
Novartis A |
5-phenylthiazole derivatives and use as pi3 kinase inhibitors
|
US7381730B2
(en)
*
|
2002-03-15 |
2008-06-03 |
Bristol-Myers Squibb Company |
3-arylquinazoline derivatives as selective estrogen receptor beta modulators
|
WO2003084544A2
(en)
*
|
2002-04-04 |
2003-10-16 |
Cv Therapeutics, Inc. |
Compounds dor increasing abca-1 expression useful for treating coronary artery disease and atherosclerosis
|
BR0309892A2
(pt)
*
|
2002-05-09 |
2011-04-05 |
Cytokinetics Inc |
composto, composição, métodos para modular a atividade da cinesina de ksp, para inibir a ksp, e para o tratamento de uma doença proliferativa celular, e, uso de um composto
|
US7214800B2
(en)
*
|
2002-05-09 |
2007-05-08 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
JP2005536475A
(ja)
*
|
2002-05-23 |
2005-12-02 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物、および方法
|
AU2003236527A1
(en)
*
|
2002-06-14 |
2003-12-31 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
EP1542703A4
(en)
*
|
2002-07-10 |
2007-11-07 |
Massachusetts Inst Technology |
SOLUBLE AND SOLUBLE PHASE SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GLYCANES
|
EP1537089A4
(en)
*
|
2002-07-23 |
2008-04-16 |
Cytokinetics Inc |
CONNECTIONS, COMPOSITIONS AND PROCEDURES
|
US20040048853A1
(en)
*
|
2002-08-21 |
2004-03-11 |
Gustave Bergnes |
Compounds, compositions, and methods
|
PL226562B1
(pl)
|
2002-09-30 |
2017-08-31 |
Bayer Pharmaceuticals Corp |
Skondensowane pochodne azolopirymidyn, leki zawierające takie pochodne oraz ich zastosowanie
|
JP2006501306A
(ja)
*
|
2002-09-30 |
2006-01-12 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物および方法
|
US20040132732A1
(en)
*
|
2002-10-21 |
2004-07-08 |
Wei Han |
Quinazolinones and derivatives thereof as factor Xa inhibitors
|
JP2006510661A
(ja)
*
|
2002-12-06 |
2006-03-30 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
Pi3kの阻害剤としてのベンズオキサジン−3−オン類及びその誘導体
|
WO2004056820A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Warner-Lambert Company Llc |
Benzoxazines and derivatives thereof as inhibitors of pi3ks
|
US20040242566A1
(en)
*
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
US7429596B2
(en)
*
|
2003-06-20 |
2008-09-30 |
The Regents Of The University Of California |
1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
|
US7410974B2
(en)
|
2003-08-08 |
2008-08-12 |
Ulysses Pharmaceutical Products, Inc. |
Halogenated Quinazolinyl nitrofurans as antibacterial agents
|
US7579357B2
(en)
|
2003-08-13 |
2009-08-25 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
US20050065144A1
(en)
*
|
2003-09-08 |
2005-03-24 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
WO2005026148A1
(en)
*
|
2003-09-08 |
2005-03-24 |
Takeda San Diego, Inc. |
Dipeptidyl peptidase inhibitors
|
CN101906106A
(zh)
|
2003-09-18 |
2010-12-08 |
康福玛医药公司 |
作为hsp90-抑制剂的新的杂环化合物
|
US20050197327A1
(en)
*
|
2003-11-03 |
2005-09-08 |
Gustave Bergnes |
Compounds, compositions, and methods
|
WO2005067901A2
(en)
*
|
2004-01-08 |
2005-07-28 |
Michigan State University |
Methods for treating and preventing hypertension and hypertension-related disorders
|
US7521455B2
(en)
*
|
2004-02-13 |
2009-04-21 |
Banyu Pharmaceutical Co. Ltd. |
Fused ring 4-oxopyrimidine derivative
|
US8507484B2
(en)
*
|
2004-02-26 |
2013-08-13 |
Kyowa Hakko Kirin Co., Ltd. |
Preventive and/or therapeutic agent for neutrophilic inflammatory diseases
|
BRPI0418639B8
(pt)
|
2004-03-15 |
2021-05-25 |
Takeda Pharmaceutical |
compostos inibidores de dipeptidil peptidase, assim como composição farmacêutica contendo os mesmos
|
WO2005095360A1
(en)
|
2004-04-02 |
2005-10-13 |
Prana Biotechnology Limited |
Neurologically-active compounds
|
US20070203109A1
(en)
*
|
2004-05-06 |
2007-08-30 |
Cancer Research Technology Limited |
Compounds And Compositions For Treatment Of Cancer
|
AU2005245875C1
(en)
|
2004-05-13 |
2017-08-31 |
Icos Corporation |
Quinazolinones as inhibitors of human phosphatidylinositol 3-kinase delta
|
CA2730540A1
(en)
*
|
2004-05-13 |
2005-12-01 |
Vanderbilt University |
Phosphoinositide 3-kinase delta selective inhibitors for inhibiting angiogenesis
|
JP2008500338A
(ja)
*
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
EP1750715A1
(en)
*
|
2004-06-04 |
2007-02-14 |
Icos Corporation |
Methods for treating mast cell disorders
|
EP1800693B1
(en)
*
|
2004-08-24 |
2013-07-17 |
Chugai Seiyaku Kabushiki Kaisha |
Adjuvant therapy with the use of anti-glypican 3 antibody
|
US20060079573A1
(en)
*
|
2004-10-10 |
2006-04-13 |
Jakob Vinten-Johansen |
Methods and compositions for preventing vasospasm
|
JP2008520744A
(ja)
|
2004-11-19 |
2008-06-19 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
抗炎症性ピラゾロピリミジン
|
EP1828192B1
(en)
|
2004-12-21 |
2014-12-03 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP1885356A2
(en)
*
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
EP1903040A4
(en)
*
|
2005-07-05 |
2010-08-04 |
Banyu Pharma Co Ltd |
PROCESS FOR PRODUCING 4 (3H) -QUINAZOLINONE DERIVATIVE
|
PL1912675T3
(pl)
*
|
2005-07-25 |
2014-10-31 |
Emergent Product Dev Seattle |
Zmniejszanie liczby komórek B za pomocą cząsteczek wiążących swoistych dla antygenów CD37 i CD20
|
CA2618479C
(en)
*
|
2005-08-26 |
2014-12-30 |
Laboratoires Serono S.A. |
Pyrazine derivatives and use as pi3k inhibitors
|
CN101374523B
(zh)
|
2005-09-14 |
2012-04-11 |
武田药品工业株式会社 |
用于治疗糖尿病的二肽基肽酶抑制剂
|
PE20070622A1
(es)
*
|
2005-09-14 |
2007-08-22 |
Takeda Pharmaceutical |
Administracion de inhibidores de dipeptidil peptidasa
|
JP5122462B2
(ja)
*
|
2005-09-16 |
2013-01-16 |
武田薬品工業株式会社 |
ジペプチジルペプチダーゼ阻害剤
|
US20070087005A1
(en)
|
2005-10-14 |
2007-04-19 |
Lazar Gregory A |
Anti-glypican-3 antibody
|
US8217042B2
(en)
|
2005-11-11 |
2012-07-10 |
Zentaris Gmbh |
Pyridopyrazines and their use as modulators of kinases
|
EP1790342A1
(de)
|
2005-11-11 |
2007-05-30 |
Zentaris GmbH |
Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege
|
WO2007054556A1
(de)
|
2005-11-11 |
2007-05-18 |
Æterna Zentaris Gmbh |
Neue pyridopyrazine und deren verwendung als modulatoren von kinasen
|
EP2348023B9
(en)
|
2005-12-13 |
2017-03-08 |
Incyte Holdings Corporation |
Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors
|
JP2009531456A
(ja)
*
|
2006-03-28 |
2009-09-03 |
武田薬品工業株式会社 |
(r)−3−アミノピペリジン二塩酸塩の調製
|
AU2007347115A1
(en)
*
|
2006-04-04 |
2008-10-23 |
The Regents Of The University Of California |
PI3 kinase antagonists
|
GB0610242D0
(en)
*
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
MX363905B
(es)
*
|
2006-06-12 |
2019-04-08 |
Aptevo Res & Development Llc |
Proteinas de union multivalentes monocatenarias con funcion efectora.
|
KR101419075B1
(ko)
*
|
2006-08-08 |
2014-07-11 |
아스카 세이야쿠 가부시키가이샤 |
퀴나졸린 유도체
|
SI2073810T1
(sl)
*
|
2006-09-13 |
2011-12-30 |
Takeda Pharmaceutical |
Uporaba 2-6(3-amino-piperidin-1-il)-3-metil-2,4-diokso-3,4-dihidro-2H-pirimidin -1-ilmetil-4-fluoro-benzonitrila za zdravljenje diabetesa, raka, avtoimunskih motenj in infekcije s HIV
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
JP2010505811A
(ja)
*
|
2006-10-04 |
2010-02-25 |
ファイザー・プロダクツ・インク |
カルシウム受容体アンタゴニストとしてのピリド[4,3−d]ピリミジン−4(3H)−オン誘導体
|
RU2009120389A
(ru)
|
2006-10-30 |
2010-12-10 |
Новартис АГ (CH) |
Гетероциклические соединения в качестве противовоспалительных агентов
|
JP5313909B2
(ja)
*
|
2006-11-13 |
2013-10-09 |
アイコス コーポレイション |
炎症性疾患および癌の処置のためのチエノピリミジノン
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
CN101932582B
(zh)
|
2007-06-13 |
2013-09-25 |
因塞特公司 |
詹纳斯激酶抑制剂(R)-3-(4-(7H-吡咯并[2,3-d]嘧啶-4-基)-1H-吡唑-1-基)-3-环戊基丙腈的盐
|
UY31137A1
(es)
*
|
2007-06-14 |
2009-01-05 |
Smithkline Beecham Corp |
Derivados de quinazolina como inhibidores de la pi3 quinasa
|
GB2467670B
(en)
|
2007-10-04 |
2012-08-01 |
Intellikine Inc |
Chemical entities and therapeutic uses thereof
|
WO2009058361A1
(en)
*
|
2007-10-31 |
2009-05-07 |
Dynavax Technologies Corp. |
Inhibition of type i ifn production
|
US20110021541A1
(en)
*
|
2007-11-13 |
2011-01-27 |
White Stephen L |
Inhibitors of human phosphatidyl-inositol 3-kinase delta
|
RU2537549C2
(ru)
*
|
2008-01-04 |
2015-01-10 |
Интелликайн ЭлЭлСи |
Некоторые химические структуры, композиции и способы
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
KR101897881B1
(ko)
|
2008-01-04 |
2018-09-12 |
인텔리카인, 엘엘씨 |
특정 화학 물질, 조성물 및 방법
|
WO2009114874A2
(en)
|
2008-03-14 |
2009-09-17 |
Intellikine, Inc. |
Benzothiazole kinase inhibitors and methods of use
|
US8637542B2
(en)
|
2008-03-14 |
2014-01-28 |
Intellikine, Inc. |
Kinase inhibitors and methods of use
|
WO2009126944A1
(en)
*
|
2008-04-11 |
2009-10-15 |
Trubion Pharmaceuticals, Inc. |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
US10517839B2
(en)
*
|
2008-06-09 |
2019-12-31 |
Cornell University |
Mast cell inhibition in diseases of the retina and vitreous
|
BRPI0915231A2
(pt)
|
2008-07-08 |
2018-06-12 |
Intellikine Inc |
compostos inibidores de quinase e métodos de uso
|
US20110224223A1
(en)
*
|
2008-07-08 |
2011-09-15 |
The Regents Of The University Of California, A California Corporation |
MTOR Modulators and Uses Thereof
|
US8703778B2
(en)
|
2008-09-26 |
2014-04-22 |
Intellikine Llc |
Heterocyclic kinase inhibitors
|
EP2358720B1
(en)
|
2008-10-16 |
2016-03-02 |
The Regents of The University of California |
Fused ring heteroaryl kinase inhibitors
|
US8476282B2
(en)
|
2008-11-03 |
2013-07-02 |
Intellikine Llc |
Benzoxazole kinase inhibitors and methods of use
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
CN102271708A
(zh)
*
|
2008-11-13 |
2011-12-07 |
新兴产品开发西雅图有限公司 |
Cd37免疫治疗联合疗法及其用途
|
CN102271683B
(zh)
|
2008-11-13 |
2014-07-09 |
吉里德卡利斯托加公司 |
恶性血液病的治疗
|
AU2009322187B2
(en)
*
|
2008-12-04 |
2015-02-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Phosphatidylinositol-3-kinase p110 delta-targeted drugs in the treatment of CNS disorders
|
CA2755935A1
(en)
|
2009-02-12 |
2010-08-19 |
Astellas Pharma Inc. |
Hetero ring derivative
|
EA019499B1
(ru)
*
|
2009-03-24 |
2014-04-30 |
ГИЛИЭД КАЛИСТОГА ЭлЭлСи |
Производные атропоизомеров 2-пуринил-3-толилхиназолинона и способы применения
|
EP2411387B1
(en)
|
2009-03-27 |
2015-08-19 |
VetDC, Inc. |
Pyrimidinyl and 1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
WO2010110686A1
(en)
|
2009-03-27 |
2010-09-30 |
Pathway Therapeutics Limited |
Pyrimidinyl and 1,3,5 triazinyl benzimidazoles and their use in cancer therapy
|
EP2421536B1
(en)
*
|
2009-04-20 |
2015-08-26 |
Gilead Calistoga LLC |
Methods of treatment for solid tumors
|
EP2427195B1
(en)
|
2009-05-07 |
2019-05-01 |
Intellikine, LLC |
Heterocyclic compounds and uses thereof
|
JP2012531435A
(ja)
*
|
2009-06-25 |
2012-12-10 |
アムジエン・インコーポレーテツド |
PI3K阻害剤としての4H−ピリド[1,2−a]ピリミジン−4−オン誘導体
|
ES2706185T3
(es)
|
2009-07-07 |
2019-03-27 |
Mei Pharma Inc |
Pirimidinil y 1,3,5-triazinil bencimidazoles y sus usos en la terapia contra el cáncer
|
WO2011011550A1
(en)
|
2009-07-21 |
2011-01-27 |
Calistoga Pharmaceuticals Inc. |
Treatment of liver disorders with pi3k inhibitors
|
EA026693B1
(ru)
|
2009-08-17 |
2017-05-31 |
Интелликайн ЭлЭлСи |
Производные бензоксазола и бензотиазола в качестве ингибиторов pi3-киназы
|
WO2011047384A2
(en)
|
2009-10-16 |
2011-04-21 |
The Regents Of The University Of California |
Methods of inhibiting ire1
|
GB0918249D0
(en)
|
2009-10-19 |
2009-12-02 |
Respivert Ltd |
Compounds
|
WO2011049625A1
(en)
|
2009-10-20 |
2011-04-28 |
Mansour Samadpour |
Method for aflatoxin screening of products
|
AU2010316780B2
(en)
|
2009-11-05 |
2015-07-16 |
Rhizen Pharmaceuticals Sa |
Novel benzopyran kinase modulators
|
ME02386B
(me)
|
2010-03-10 |
2016-09-20 |
Incyte Holdings Corp |
Derivati piperidin-4-il azetidina kao inhibitori jak1
|
KR102303885B1
(ko)
|
2010-05-21 |
2021-09-24 |
인사이트 홀딩스 코포레이션 |
Jak 저해제에 대한 국소 제형
|
CN103002738A
(zh)
|
2010-05-21 |
2013-03-27 |
英特利凯恩有限责任公司 |
用于激酶调节的化学化合物、组合物和方法
|
EP3399026A1
(en)
|
2010-06-14 |
2018-11-07 |
The Scripps Research Institute |
Reprogramming of cells to a new fate
|
CN103025725B
(zh)
|
2010-08-10 |
2015-09-16 |
安斯泰来制药有限公司 |
杂环化合物
|
PL2611300T3
(pl)
|
2010-09-03 |
2016-10-31 |
|
Podstawione skondensowane pochodne dihydropirymidynonów
|
WO2012040634A1
(en)
|
2010-09-24 |
2012-03-29 |
Gilead Calistoga Llc |
Atropisomers of pi3k-inhibiting compounds
|
WO2012044641A1
(en)
|
2010-09-29 |
2012-04-05 |
Pathway Therapeutics Inc. |
1,3,5-triazinyl benzimidazole sulfonamides and their use in cancer therapy
|
UY33337A
(es)
|
2010-10-18 |
2011-10-31 |
Respivert Ltd |
DERIVADOS SUSTITUIDOS DE 1H-PIRAZOL[ 3,4-d]PIRIMIDINA COMO INHIBIDORES DE LAS FOSFOINOSITIDA 3-QUINASAS
|
CN103298474B
(zh)
|
2010-11-10 |
2016-06-29 |
无限药品股份有限公司 |
杂环化合物及其用途
|
EP2640723A1
(en)
|
2010-11-19 |
2013-09-25 |
Incyte Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
NZ612909A
(en)
|
2011-01-10 |
2015-09-25 |
Infinity Pharmaceuticals Inc |
Processes for preparing isoquinolinones and solid forms of isoquinolinones
|
AR085397A1
(es)
|
2011-02-23 |
2013-09-25 |
Intellikine Inc |
Combinacion de inhibidores de quinasa y sus usos
|
WO2012116237A2
(en)
|
2011-02-23 |
2012-08-30 |
Intellikine, Llc |
Heterocyclic compounds and uses thereof
|
KR101940831B1
(ko)
|
2011-03-28 |
2019-01-21 |
메이 파마, 아이엔씨. |
(알파-치환된 아르알킬아미노 및 헤테로아릴알킬아미노)피리미딘일 및 1,3,5-트라이아진일 벤즈이미다졸, 이들을 함유하는 약학 조성물, 및 증식성 질병의 치료에 사용하기 위한 이들 화합물
|
CN102731525A
(zh)
*
|
2011-04-08 |
2012-10-17 |
上海艾力斯医药科技有限公司 |
苯并吗啉衍生物
|
EP2518070A1
(en)
|
2011-04-29 |
2012-10-31 |
Almirall, S.A. |
Pyrrolotriazinone derivatives as PI3K inhibitors
|
MY168757A
(en)
|
2011-05-04 |
2018-12-04 |
Rhizen Pharmaceuticals S A |
Novel compounds as modulators of protein kinases
|
US8691807B2
(en)
|
2011-06-20 |
2014-04-08 |
Incyte Corporation |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors
|
US8969363B2
(en)
|
2011-07-19 |
2015-03-03 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
MX2014000648A
(es)
|
2011-07-19 |
2014-09-25 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y sus usos.
|
TW201311663A
(zh)
|
2011-08-29 |
2013-03-16 |
Infinity Pharmaceuticals Inc |
雜環化合物及其用途
|
MX370814B
(es)
|
2011-09-02 |
2020-01-08 |
Univ California |
Pirazolo[3,4-d]pirimidinas sustituidas y usos de las mismas.
|
WO2013134288A1
(en)
|
2012-03-05 |
2013-09-12 |
Gilead Calistoga Llc |
Polymorphic forms of (s)-2-(1-(9h-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3h)-one
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
PL2870157T3
(pl)
|
2012-07-04 |
2018-01-31 |
Rhizen Pharmaceuticals S A |
Selektywne inhibitory pi3k delta
|
TW201414734A
(zh)
|
2012-07-10 |
2014-04-16 |
Takeda Pharmaceutical |
氮雜吲哚衍生物
|
SG11201501173SA
(en)
*
|
2012-08-08 |
2015-05-28 |
Kbp Biosciences Co Ltd |
PI3Kδ INHIBITOR
|
RU2015115631A
(ru)
|
2012-09-26 |
2016-11-20 |
Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния |
Модулирование ire1
|
JP2015533181A
(ja)
*
|
2012-10-16 |
2015-11-19 |
アルミラル・ソシエダッド・アノニマAlmirall, S.A. |
Pi3k阻害剤としてのピロロトリアジノン誘導体
|
KR20150079745A
(ko)
|
2012-11-08 |
2015-07-08 |
리젠 파마슈티컬스 소시에떼 아노님 |
Pde4 억제제 및 pi3 델타 또는 이중 pi3 델타-감마 키나아제 억제제를 함유하는 약제학적 조성물
|
EA201590930A1
(ru)
|
2012-11-15 |
2015-08-31 |
Инсайт Корпорейшн |
Лекарственные формы руксолитиниба с замедленным высвобождением
|
RU2658006C2
(ru)
*
|
2012-11-16 |
2018-06-19 |
Мерк Шарп И Доум Корп. |
Пуриновые ингибиторы человеческой фосфатидилинозит 3-киназы дельта
|
CA2895785A1
(en)
|
2012-12-21 |
2014-06-26 |
Jerry Evarts |
Isoquinolinone or quinazolinone phosphatidylinositol 3-kinase inhibitors
|
CA2895782C
(en)
|
2012-12-21 |
2017-08-22 |
Gilead Calistoga Llc |
Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
|
JP6397831B2
(ja)
|
2013-03-06 |
2018-09-26 |
インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation |
Jak阻害剤の製造方法及びその中間体
|
WO2014151386A1
(en)
|
2013-03-15 |
2014-09-25 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
TW201522341A
(zh)
|
2013-03-15 |
2015-06-16 |
Respivert Ltd |
化合物
|
US9227977B2
(en)
|
2013-03-15 |
2016-01-05 |
Respivert Ltd. |
Phosphoinositide 3-kinase inhibitors
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
AR096621A1
(es)
|
2013-06-14 |
2016-01-20 |
Gilead Sciences Inc |
Inhibidores de isómeros de la fosfatidilinositol 3-quinasa (pi3k)
|
WO2015001491A1
(en)
|
2013-07-02 |
2015-01-08 |
Rhizen Pharmaceuticals Sa |
Pi3k protein kinase inhibitors, particularly delta and/or gamma inhibitors
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
MY195091A
(en)
|
2013-08-07 |
2023-01-10 |
Incyte Corp |
Sustained Release Dosage Forms for a JAK1 Inhibitor
|
KR20160060100A
(ko)
|
2013-09-22 |
2016-05-27 |
칼리토르 사이언시즈, 엘엘씨 |
치환된 아미노피리미딘 화합물 및 이용 방법
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
NZ718430A
(en)
|
2013-10-04 |
2021-12-24 |
Infinity Pharmaceuticals Inc |
Heterocyclic compounds and uses thereof
|
JP6584391B2
(ja)
|
2013-10-10 |
2019-10-02 |
アセチロン ファーマシューティカルズ インコーポレイテッドAcetylon Pharmaceuticals,Inc. |
非ホジキンリンパ腫を治療するための、hdac阻害剤単独またはpi3k阻害剤との組み合わせ
|
WO2015061204A1
(en)
|
2013-10-21 |
2015-04-30 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
ES2752552T3
(es)
|
2013-12-20 |
2020-04-06 |
Gilead Calistoga Llc |
Métodos de proceso para inhibidores de fosfatidilinositol 3-quinasa
|
WO2015095605A1
(en)
|
2013-12-20 |
2015-06-25 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
TW201620904A
(zh)
|
2014-01-09 |
2016-06-16 |
武田藥品工業有限公司 |
氮雜吲哚衍生物
|
WO2015106014A1
(en)
|
2014-01-09 |
2015-07-16 |
Takeda Pharmaceutical Company Limited |
Azaindole derivatives
|
AU2015231413B2
(en)
|
2014-03-19 |
2020-04-23 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds for use in the treatment of PI3K-gamma mediated disorders
|
US20150320755A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
WO2015168079A1
(en)
|
2014-04-29 |
2015-11-05 |
Infinity Pharmaceuticals, Inc. |
Pyrimidine or pyridine derivatives useful as pi3k inhibitors
|
DK3149000T3
(da)
|
2014-05-27 |
2021-08-30 |
Rhizen Pharmaceuticals S A |
Krystallinsk tosylatsalt af en pi3k-delta-selektiv inhibitor til anvendelse i farmaceutiske formuleringer
|
BR112016028814A2
(pt)
|
2014-06-13 |
2017-08-22 |
Gilead Sciences Inc |
?composição farmacêutica, métodos de tratamento de uma doença ou condição, de inibição de reações imunitárias ou crescimento excessivo ou destrutivo ou de proliferação de células cancerosas, kit, composto, um sal, um isômero, ou uma mistura farmaceuticamente aceitável do mesmo, e, uso de um composto, de um sal, de um isômero, ou de uma mistura farmaceuticamente aceitável do mesmo?
|
EA201692266A1
(ru)
*
|
2014-06-13 |
2017-06-30 |
Джилид Сайэнс, Инк. |
Ингибиторы фосфатидилинозитол-3-киназы
|
BR112016028818A2
(pt)
*
|
2014-06-13 |
2017-08-22 |
Gilead Sciences Inc |
composição farmacêutica, métodos de tratamento de uma doença ou condição, de inibição da atividade de um polipeptídeo de fosfatidilinositol 3-quinase e de inibição de reações imunes excessivas ou destrutivas ou crescimento ou proliferação de células cancerosas, kit, composto, sal, isômero, ou uma mistura farmaceuticamente aceitável do mesmo, e, uso de um composto, um sal, isômero, ou uma mistura farmaceuticamente aceitável do mesmo.
|
US11021467B2
(en)
|
2014-06-13 |
2021-06-01 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|
SG11201609540TA
(en)
|
2014-06-13 |
2016-12-29 |
Gilead Sciences Inc |
Phosphatidylinositol 3-kinase inhibitors
|
SG11201610341PA
(en)
|
2014-06-24 |
2017-01-27 |
Gilead Sciences Inc |
Phosphatidylinositol 3-kinase inhibitors
|
AU2015283671B2
(en)
|
2014-07-04 |
2018-07-05 |
Lupin Limited |
Quinolizinone derivatives as Pl3K inhibitors
|
US9708348B2
(en)
|
2014-10-03 |
2017-07-18 |
Infinity Pharmaceuticals, Inc. |
Trisubstituted bicyclic heterocyclic compounds with kinase activities and uses thereof
|
WO2017002934A1
(ja)
|
2015-07-01 |
2017-01-05 |
中外製薬株式会社 |
Gpc3標的治療剤が有効である患者に投与されるgpc3標的治療剤
|
US9957267B2
(en)
|
2015-07-01 |
2018-05-01 |
Crinetics Pharmaceuticals, Inc. |
Somatostatin modulators and uses thereof
|
US9643980B2
(en)
|
2015-07-02 |
2017-05-09 |
Genentech, Inc. |
Benzoxazepin oxazolidinone compounds and methods of use
|
SI3317284T1
(sl)
|
2015-07-02 |
2020-02-28 |
F. Hoffmann-La Roche Ag |
Spojine benzoksazepin oksazolidinona in načini uporabe
|
LT3337506T
(lt)
|
2015-08-21 |
2021-10-11 |
Morphosys Ag |
Deriniai ir jų panaudojimas
|
MX2018003058A
(es)
|
2015-09-14 |
2018-08-01 |
Infinity Pharmaceuticals Inc |
Formas solidas de derivados de isoquinolinona, proceso de fabricacion, composiciones que las contienen y metodos de uso de las mismas.
|
JP7002446B2
(ja)
|
2015-09-21 |
2022-03-04 |
アプティーボ リサーチ アンド デベロップメント エルエルシー |
Cd3結合ポリペプチド
|
WO2017103825A1
(en)
|
2015-12-18 |
2017-06-22 |
Lupin Limited |
Quinolizinone derivatives as pi3k inhibitors
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
WO2017214269A1
(en)
|
2016-06-08 |
2017-12-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
JP7054681B2
(ja)
|
2016-06-24 |
2022-04-14 |
インフィニティー ファーマシューティカルズ, インコーポレイテッド |
組合せ療法
|
EP3272348A1
(en)
|
2016-07-21 |
2018-01-24 |
LEK Pharmaceuticals d.d. |
Pharmaceutical composition comprising idelalisib
|
WO2018057808A1
(en)
|
2016-09-23 |
2018-03-29 |
Gilead Sciences, Inc. |
Benzimidazole derivatives and their use as phosphatidylinositol 3-kinase inhibitors
|
TW201825465A
(zh)
|
2016-09-23 |
2018-07-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
TW201813963A
(zh)
|
2016-09-23 |
2018-04-16 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
TW201815787A
(zh)
|
2016-09-23 |
2018-05-01 |
美商基利科學股份有限公司 |
磷脂醯肌醇3-激酶抑制劑
|
CN108239074B
(zh)
*
|
2016-12-26 |
2021-07-06 |
中国医学科学院药物研究所 |
喹唑啉类化合物及其制备方法、用途和药物组合物
|
EP4169918A1
(en)
*
|
2016-12-26 |
2023-04-26 |
Institute of Materia Medica, Chinese Academy of Medical Sciences |
Quinazoline compound and preparation method, application, and pharmaceutical compostion thereof
|
EP3658560A4
(en)
|
2017-07-25 |
2021-01-06 |
Crinetics Pharmaceuticals, Inc. |
SOMATOSTAT IN MODULATORS AND USES THEREOF
|
JP2020529418A
(ja)
*
|
2017-07-31 |
2020-10-08 |
ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨークThe Trustees Of Columbia University In The City Of New York |
T細胞急性リンパ芽球性白血病を治療するための化合物、組成及び方法
|
CA3072476A1
(en)
|
2017-08-14 |
2019-02-21 |
Mei Pharma, Inc. |
Combination therapy
|
WO2019113487A1
(en)
|
2017-12-08 |
2019-06-13 |
Incyte Corporation |
Low dose combination therapy for treatment of myeloproliferative neoplasms
|
CR20200379A
(es)
|
2018-01-30 |
2021-03-05 |
Incyte Corp |
Procesos e intermedio para elaborar un inhibidor de jak campo técnico
|
WO2019178596A1
(en)
|
2018-03-16 |
2019-09-19 |
Johnson Matthey Public Limited Company |
Pyridine or n,n-dimethyl acetamide solvated solid state forms of solvated idelalisib, their use and preparation
|
CA3095487A1
(en)
|
2018-03-30 |
2019-10-03 |
Incyte Corporation |
Treatment of hidradenitis suppurativa using jak inhibitors
|
US20220112217A1
(en)
*
|
2018-08-21 |
2022-04-14 |
Medshine Discovery Inc. |
Pyrazolopyrimidine derivative and use thereof as pi3k inhibitor
|
EP3877511A1
(en)
|
2018-11-05 |
2021-09-15 |
Iovance Biotherapeutics, Inc. |
Expansion of tils utilizing akt pathway inhibitors
|
CN111269231B
(zh)
*
|
2018-12-04 |
2023-06-09 |
安徽中科拓苒药物科学研究有限公司 |
一种选择性PI3Kδ抑制剂及其用途
|
WO2020201073A1
(en)
*
|
2019-03-29 |
2020-10-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of keloid, hypertrophic scars and/or hyperpigmentation disorders
|
WO2020247679A1
(en)
*
|
2019-06-04 |
2020-12-10 |
Vanderbilt University |
Wdr5 inhibitors and modulators
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
CN112830927A
(zh)
*
|
2021-03-04 |
2021-05-25 |
山西科灜科技有限公司 |
一种嘌呤喹唑啉酮衍生物及其制备方法
|