CN1020944C
(zh)
|
1990-01-30 |
1993-05-26 |
阿图尔-费希尔股份公司费希尔厂 |
紧固件
|
US6515117B2
(en)
*
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
NZ521369A
(en)
*
|
2000-03-17 |
2004-07-30 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives, medicinal compositions containing the same and intermediates for the preparation of the derivatives
|
SK287811B6
(sk)
|
2000-09-29 |
2011-10-04 |
Kissei Pharmaceutical Co., Ltd |
Glukopyranozyloxybenzylbenzénový derivát, farmaceutická kompozícia a ľudský SGLT2-inhibítor tento derivát obsahujúci a použitie tohto derivátu
|
WO2002044192A1
(fr)
*
|
2000-11-30 |
2002-06-06 |
Kissei Pharmaceutical Co., Ltd. |
Derives de glucopyranosyloxybenzylbenzene, compositions medicinales contenant ces derives et produits intermediaires obtenus lors de l'elaboration de ces compositions
|
EP1354888B1
(en)
|
2000-12-28 |
2009-05-20 |
Kissei Pharmaceutical Co., Ltd. |
Glucopyranosyloxypyrazole derivatives and use thereof in medicines
|
TWI255817B
(en)
*
|
2001-02-14 |
2006-06-01 |
Kissei Pharmaceutical |
Glucopyranosyloxybenzylbenzene derivatives and medicinal use thereof
|
CA2442917C
(en)
|
2001-04-04 |
2011-02-01 |
Ortho-Mcneil Pharmaceutical, Inc. |
Combination therapy comprising glucose reabsorption inhibitors and ppar modulators
|
CN100384430C
(zh)
|
2001-04-04 |
2008-04-30 |
奥索-麦克尼尔药品公司 |
含有葡萄糖重吸收抑制剂和维生素a类-x受体调节剂的联合治疗
|
CA2455300A1
(en)
*
|
2001-06-20 |
2003-01-03 |
Kissei Pharmaceutical Co., Ltd. |
Nitrogen-containing heterocyclic derivative, medicinal composition containing the same, medicinal use thereof, and intermediate therefor
|
WO2003011880A1
(fr)
*
|
2001-07-31 |
2003-02-13 |
Kissei Pharmaceutical Co., Ltd. |
Derive de glucopyranosyloxybenzylbenzene, composition medicinale contenant ce derive, usage medicinal de cette composition et produit intermediaire pour produire cette composition
|
PL210710B1
(pl)
*
|
2002-03-22 |
2012-02-29 |
Kissei Pharmaceutical |
Krystaliczne postaci 2-(4-metoksybenzylo) fenylo-6-O-etoksykarbonylo-ß-D-glukopiranozydu, ich zastosowanie oraz zawierająca je kompozycja farmaceutyczna
|
US7956041B2
(en)
*
|
2002-04-26 |
2011-06-07 |
Ajinomoto Co., Inc. |
Prophylactic and therapeutic agent of diabetes mellitus
|
DE60332743D1
(de)
*
|
2002-08-08 |
2010-07-08 |
Kissei Pharmaceutical |
Pyrazolderivat, dieses enthaltende medizinische zusammensetzung, medizinische verwendung davon, und zwischenprodukt für dessen herstellung
|
EP1528066A4
(en)
*
|
2002-08-09 |
2007-05-02 |
Taisho Pharmaceutical Co Ltd |
ARYL-t-THIO-B-GLUCOPYRANOSIDE DERIVATIVES AND DIABETES CONTAINING THEM
|
JP4651934B2
(ja)
*
|
2002-12-04 |
2011-03-16 |
キッセイ薬品工業株式会社 |
ベンジルフェノール誘導体、それを含有する医薬組成物およびその医薬用途
|
DE10258007B4
(de)
*
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
DE10258008B4
(de)
*
|
2002-12-12 |
2006-02-02 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
EP1577317A4
(en)
*
|
2002-12-25 |
2007-05-09 |
Kissei Pharmaceutical |
NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES, MEDICINAL COMPOSITIONS COMPRISING SAID DERIVATIVES AND MEDICAL USE OF SAID DERIVATIVES
|
JP2004300102A
(ja)
*
|
2003-03-31 |
2004-10-28 |
Kissei Pharmaceut Co Ltd |
縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
|
US7439232B2
(en)
*
|
2003-04-01 |
2008-10-21 |
Taisho Pharmaceutical Co., Ltd. |
Heteroaryl 5-thio-β-D-glucopyranoside derivatives and therapeutic agents for diabetes containing the same
|
AR048376A1
(es)
*
|
2003-08-01 |
2006-04-26 |
Janssen Pharmaceutica Nv |
C- glicosidos heterociclos fusionados sustituidos
|
US8785403B2
(en)
|
2003-08-01 |
2014-07-22 |
Mitsubishi Tanabe Pharma Corporation |
Glucopyranoside compound
|
US7129220B2
(en)
*
|
2003-08-01 |
2006-10-31 |
Janssen Pharmaceutica N.V |
Substituted indole-O-glucosides
|
DK2896397T4
(da)
*
|
2003-08-01 |
2020-11-16 |
Mitsubishi Tanabe Pharma Corp |
Nye forbindelser med hæmmende aktivitet mod natriumafhængig glukosetransportør
|
EP1679966A4
(en)
*
|
2003-08-01 |
2009-05-27 |
Janssen Pharmaceutica Nv |
BENZIMIDAZOLE-, BENZTRIAZOLE- AND BENZIMIDAZOLONE-SUBSTITUTED O-GLUCOSIDES
|
UA86042C2
(en)
*
|
2003-08-01 |
2009-03-25 |
Янссен Фармацевтика Н.В. |
Substituted indazole-o-glucosides
|
EA010655B1
(ru)
*
|
2003-08-01 |
2008-10-30 |
Янссен Фармацевтика Н.В. |
Замещенные индазол-о-глюкозиды
|
JP4568488B2
(ja)
*
|
2003-09-05 |
2010-10-27 |
花王株式会社 |
イソプロピルメチルフェノール配糖体
|
EP1516665A1
(en)
|
2003-09-18 |
2005-03-23 |
Sony International (Europe) GmbH |
A method of immobilizing and stretching a nucleic acid on a substrate
|
US7371732B2
(en)
|
2003-12-22 |
2008-05-13 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture
|
DE10361133A1
(de)
*
|
2003-12-22 |
2005-07-21 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Glucopyranosyloxy-substituierte Aromaten, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
US8058245B2
(en)
*
|
2004-03-04 |
2011-11-15 |
Kissei Pharmaceutical Co., Ltd. |
Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
|
CA2557801C
(en)
|
2004-03-16 |
2013-06-25 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzol derivatives, drugs containing said compounds, the use thereof and method for the production thereof
|
JPWO2005095373A1
(ja)
*
|
2004-03-31 |
2008-02-21 |
キッセイ薬品工業株式会社 |
ナフタレン誘導体、それを含有する医薬組成物およびその医薬用途
|
JPWO2005095372A1
(ja)
*
|
2004-03-31 |
2008-02-21 |
キッセイ薬品工業株式会社 |
ナフタレン誘導体、それを含有する医薬組成物及びその医薬用途
|
US20070185197A1
(en)
*
|
2004-03-31 |
2007-08-09 |
Hideki Fujikura |
Phenol derivative, medicinal composition containing the same, and medicinal use thereof
|
US20050261292A1
(en)
*
|
2004-05-19 |
2005-11-24 |
Solvay Pharmaceuticals Gmbh |
Pharmaceutical composition containing N-sulfamoyl-N'-arylpiperazines for the treatment or inhibition of obesity and related conditions
|
TW200606129A
(en)
|
2004-07-26 |
2006-02-16 |
Chugai Pharmaceutical Co Ltd |
Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
|
WO2006035796A1
(ja)
*
|
2004-09-29 |
2006-04-06 |
Kissei Pharmaceutical Co., Ltd. |
1-(β-D-グリコピラノシル)-3-置換含窒素ヘテロ環化合物、それを含有する医薬組成物及びその医薬用途
|
DE102004058449A1
(de)
*
|
2004-12-03 |
2006-06-14 |
Merck Patent Gmbh |
Tetrahydropyranderivate
|
US7687469B2
(en)
|
2004-12-16 |
2010-03-30 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
TW200637869A
(en)
|
2005-01-28 |
2006-11-01 |
Chugai Pharmaceutical Co Ltd |
The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
|
MY147375A
(en)
*
|
2005-01-31 |
2012-11-30 |
Mitsubishi Tanabe Pharma Corp |
Indole derivatives
|
JP5073948B2
(ja)
*
|
2005-01-31 |
2012-11-14 |
田辺三菱製薬株式会社 |
医薬組成物
|
AR053329A1
(es)
*
|
2005-01-31 |
2007-05-02 |
Tanabe Seiyaku Co |
Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
|
ATE445608T1
(de)
|
2005-02-23 |
2009-10-15 |
Boehringer Ingelheim Int |
Glucopyranosylsubstituierte ((hetero)arylethynyl- benzyl)-benzenderivative und deren verwendung als inhibitoren des natriumabhängigen glucose- cotransporters typ 2 (sglt2)
|
ATE453656T1
(de)
|
2005-04-15 |
2010-01-15 |
Boehringer Ingelheim Int |
Glucopyranosyl-substituierte (heteroaryloxy- benzyl)-benzen-derivate als sglt-inhibitoren
|
US7723309B2
(en)
|
2005-05-03 |
2010-05-25 |
Boehringer Ingelheim International Gmbh |
Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
UA91546C2
(uk)
|
2005-05-03 |
2010-08-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
|
US7772191B2
(en)
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
JP5128474B2
(ja)
|
2005-07-27 |
2013-01-23 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル−置換((ヘテロ)シクロアルキルエチニル−ベンジル)−ベンゼン誘導体、該化合物を含有する薬剤、それらの使用及びそれらの製造方法
|
UY29694A1
(es)
*
|
2005-07-28 |
2007-02-28 |
Boehringer Ingelheim Int |
Metodos para prevenir y tratar trastornos metabolicos y nuevos derivados de pirazol-o-glucosido
|
DE602006017566D1
(de)
*
|
2005-08-30 |
2010-11-25 |
Boehringer Ingelheim Pharma |
Glucopyranosyl-substituierte benzyl-derivate, medikamente mit solchen verbindungen, ihre verwendung und herstellungsverfahren dafür
|
EP1926720B1
(en)
|
2005-09-08 |
2010-12-15 |
Boehringer Ingelheim International GmbH |
CRYSTALLINE FORMS OF 1-CHLORO-4-(ß-D-GLUCOPYRANOS-1-YL)-2-(4-ETHYNYL-BENZYL)-BENZENE, METHODS FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
|
AR056195A1
(es)
|
2005-09-15 |
2007-09-26 |
Boehringer Ingelheim Int |
Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos
|
AR059489A1
(es)
|
2006-02-15 |
2008-04-09 |
Boehringer Ingelheim Vetmed |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
EP1854806A1
(en)
*
|
2006-05-02 |
2007-11-14 |
MPG Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Thioglycosides as pharmaceutically active agents
|
PE20080697A1
(es)
|
2006-05-03 |
2008-08-05 |
Boehringer Ingelheim Int |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
AU2007252432B2
(en)
*
|
2006-05-19 |
2011-11-17 |
Taisho Pharmaceutical Co., Ltd. |
C-phenyl glycitol compound
|
US7803778B2
(en)
*
|
2006-05-23 |
2010-09-28 |
Theracos, Inc. |
Glucose transport inhibitors and methods of use
|
WO2007143052A1
(en)
*
|
2006-06-01 |
2007-12-13 |
Glycomimetics, Inc. |
Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
|
DE102006028862A1
(de)
|
2006-06-23 |
2007-12-27 |
Merck Patent Gmbh |
3-Amino-imidazo[1,2-a]pyridinderivate
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
TWI418556B
(zh)
*
|
2006-07-27 |
2013-12-11 |
Mitsubishi Tanabe Pharma Corp |
吲哚衍生物
|
TW200817424A
(en)
*
|
2006-08-04 |
2008-04-16 |
Daiichi Sankyo Co Ltd |
Benzylphenyl glucopyranoside derivatives
|
TWI499414B
(zh)
|
2006-09-29 |
2015-09-11 |
Lexicon Pharmaceuticals Inc |
鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
|
UY30730A1
(es)
*
|
2006-12-04 |
2008-07-03 |
Mitsubishi Tanabe Pharma Corp |
Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
|
ES2397664T3
(es)
*
|
2006-12-04 |
2013-03-08 |
Janssen Pharmaceutica, N.V. |
Derivados de glucopiranósilo que contienen tienilo como antidiabéticos
|
MX2009005935A
(es)
|
2006-12-06 |
2009-06-30 |
Smithkline Beecham Corp |
Compuestos biciclicos y su uso como anti-diabeticos.
|
US7795228B2
(en)
*
|
2006-12-28 |
2010-09-14 |
Theracos, Inc. |
Spiroheterocyclic glycosides and methods of use
|
DE102007008420A1
(de)
|
2007-02-21 |
2008-08-28 |
Merck Patent Gmbh |
Benzimidazolderivate
|
US7846945B2
(en)
*
|
2007-03-08 |
2010-12-07 |
Lexicon Pharmaceuticals, Inc. |
Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use
|
AU2008232419B2
(en)
|
2007-04-02 |
2013-06-20 |
Theracos, Inc. |
Benzylic glycoside derivatives and methods of use
|
EP2183263B1
(en)
*
|
2007-07-26 |
2011-10-26 |
Lexicon Pharmaceuticals, Inc. |
Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
|
PE20090938A1
(es)
|
2007-08-16 |
2009-08-08 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende un derivado de benceno sustituido con glucopiranosilo
|
JP4809931B2
(ja)
*
|
2007-08-23 |
2011-11-09 |
セラコス・インコーポレイテッド |
ベンジルベンゼン誘導体およびその使用方法
|
ES2647504T3
(es)
|
2007-09-10 |
2017-12-21 |
Janssen Pharmaceutica N.V. |
Proceso para la preparación de compuestos útiles como inhibidores de SGLT
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
PT2247602E
(pt)
*
|
2007-11-30 |
2013-07-10 |
Novartis Ag |
Derivados de adamantil o-glucuronido como inibidores da dipeptidilpeptidase iv para o tratamento de diabetes
|
UA101004C2
(en)
|
2007-12-13 |
2013-02-25 |
Теракос, Инк. |
Derivatives of benzylphenylcyclohexane and use thereof
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
WO2009096503A1
(ja)
*
|
2008-01-31 |
2009-08-06 |
Daiichi Sankyo Company, Limited |
ベンジルフェニルグルコピラノシド誘導体
|
FR2929615B1
(fr)
*
|
2008-04-02 |
2010-12-17 |
Tfchem |
Composes c-aryl glycosides pour le traitement du diabete et de l'obesite.
|
DE102008017590A1
(de)
|
2008-04-07 |
2009-10-08 |
Merck Patent Gmbh |
Glucopyranosidderivate
|
CN102105153B
(zh)
|
2008-05-22 |
2014-03-05 |
百时美施贵宝公司 |
Sglt2抑制剂的医药用途和含该抑制剂的组合物
|
JP6071198B2
(ja)
|
2008-07-15 |
2017-02-01 |
テラコス,インコーポレーテッド |
重水素化ベンジルベンゼン誘導体及び使用方法
|
NZ591818A
(en)
|
2008-08-22 |
2013-01-25 |
Theracos Inc |
Processes for the preparation of sglt2 inhibitors
|
JP4825322B1
(ja)
*
|
2008-08-28 |
2011-11-30 |
ファイザー・インク |
ジオキサ−ビシクロ[3.2.1]オクタン−2,3,4−トリオール誘導体
|
US9056850B2
(en)
*
|
2008-10-17 |
2015-06-16 |
Janssen Pharmaceutica N.V. |
Process for the preparation of compounds useful as inhibitors of SGLT
|
CN101445527B
(zh)
*
|
2008-12-25 |
2011-09-14 |
天津药物研究院 |
五元芳杂环甲苯基葡萄糖苷、其制备方法和用途
|
WO2010092125A1
(en)
|
2009-02-13 |
2010-08-19 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition comprising a sglt2 inhibitor, a dpp-iv inhibitor and optionally a further antidiabetic agent and uses thereof
|
US20110009347A1
(en)
|
2009-07-08 |
2011-01-13 |
Yin Liang |
Combination therapy for the treatment of diabetes
|
CN102482250B
(zh)
|
2009-07-10 |
2014-11-19 |
詹森药业有限公司 |
1-(β-D-吡喃葡糖基)-4-甲基-3-[5-(4-氟苯基)-2-噻吩基甲基]苯的结晶方法
|
BR112012007085B8
(pt)
|
2009-09-30 |
2021-05-25 |
Boehringer Ingelheim Int |
processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
|
PL2483286T3
(pl)
|
2009-09-30 |
2017-04-28 |
Boehringer Ingelheim International Gmbh |
Sposób wytwarzania postaci krystalicznej 1-chloro-4-(β-D-glukopiranoz-1-ylo)-2-[4-((S)-tetrahydrofuran-3-yloksy)-benzylo]-benzenu
|
US10610489B2
(en)
|
2009-10-02 |
2020-04-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
|
CN102648196B
(zh)
*
|
2009-10-14 |
2016-04-27 |
詹森药业有限公司 |
可用作sglt2的抑制剂的化合物的制备方法
|
EP2491050A2
(en)
|
2009-10-20 |
2012-08-29 |
Novartis AG |
Glycoside derivative and uses thereof
|
US8163704B2
(en)
|
2009-10-20 |
2012-04-24 |
Novartis Ag |
Glycoside derivatives and uses thereof
|
PT2496583E
(pt)
|
2009-11-02 |
2015-01-14 |
Pfizer |
Derivados de dioxa-biciclo[3.2.1]octano-2,3,4-triol
|
WO2011070592A2
(en)
|
2009-12-09 |
2011-06-16 |
Panacea Biotec Ltd. |
Novel sugar derivatives
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
CN108354930A
(zh)
|
2010-05-11 |
2018-08-03 |
詹森药业有限公司 |
包含1-(β-D-吡喃葡萄糖基)-2-噻吩基-甲基苯衍生物的药物制剂
|
WO2011153712A1
(en)
|
2010-06-12 |
2011-12-15 |
Theracos, Inc. |
Crystalline form of benzylbenzene sglt2 inhibitor
|
KR101466838B1
(ko)
|
2010-06-18 |
2014-11-28 |
주식회사 녹십자 |
Sglt2 억제제로서의 티아졸 유도체 및 이를 포함하는 약학 조성물
|
WO2012025857A1
(en)
|
2010-08-23 |
2012-03-01 |
Hetero Research Foundation |
Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors
|
US8921328B2
(en)
|
2010-09-14 |
2014-12-30 |
Glycomimetics, Inc. |
E-selectin antagonists
|
UY33937A
(es)
|
2011-03-07 |
2012-09-28 |
Boehringer Ingelheim Int |
Composiciones farmacéuticas que contienen inhibidores de dpp-4 y/o sglt-2 y metformina
|
US10544135B2
(en)
|
2011-04-13 |
2020-01-28 |
Janssen Pharmaceutica Nv |
Process for the preparation of compounds useful as inhibitors of SGLT2
|
BR112013026361A2
(pt)
|
2011-04-14 |
2016-12-27 |
Novartis Ag |
derivados de glicosídeo e usos dos mesmos
|
US8614195B2
(en)
|
2011-04-14 |
2013-12-24 |
Novartis Ag |
Glycoside derivatives and uses thereof
|
TWI542596B
(zh)
|
2011-05-09 |
2016-07-21 |
健生藥品公司 |
(2s,3r,4r,5s,6r)-2-(3-((5-(4-氟苯基)噻吩-2-基)甲基)-4-甲基苯基)-6-(羥甲基)四氫-2h-哌喃-3,4,5-三醇之l-脯胺酸及檸檬酸共晶體
|
EP3296310A1
(en)
|
2011-12-22 |
2018-03-21 |
GlycoMimetics, Inc. |
E-selectin antagonist compounds, compositions, and methods of use
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US9193751B2
(en)
|
2012-04-10 |
2015-11-24 |
Theracos, Inc. |
Process for the preparation of benzylbenzene SGLT2 inhibitors
|
HUE038423T2
(hu)
|
2012-12-07 |
2018-10-29 |
Glycomimetics Inc |
E-szelektin antagonistákat felhasználó vegyületek, készítmények és eljárások vérképzõ sejtek mobilizációjára
|
EP2774619B1
(de)
|
2013-03-04 |
2016-05-18 |
BioActive Food GmbH |
Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen
|
CN103127513A
(zh)
*
|
2013-03-11 |
2013-06-05 |
乔文龙 |
一种治疗糖尿病及并发症的α-糖苷酶抑制剂和羟甲基戊二酰辅酶A还原酶抑制剂组合物
|
US8652527B1
(en)
|
2013-03-13 |
2014-02-18 |
Upsher-Smith Laboratories, Inc |
Extended-release topiramate capsules
|
EP2968375B1
(en)
|
2013-03-14 |
2019-06-12 |
MSD International GmbH |
Methods for preparing sglt2 inhibitors
|
US9101545B2
(en)
|
2013-03-15 |
2015-08-11 |
Upsher-Smith Laboratories, Inc. |
Extended-release topiramate capsules
|
US11813275B2
(en)
|
2013-04-05 |
2023-11-14 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US20140303098A1
(en)
|
2013-04-05 |
2014-10-09 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US20140303097A1
(en)
|
2013-04-05 |
2014-10-09 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
CA3175715A1
(en)
|
2013-04-18 |
2014-10-23 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
CN105611920B
(zh)
|
2013-10-12 |
2021-07-16 |
泰拉科斯萨普有限责任公司 |
羟基-二苯甲烷衍生物的制备
|
US10603300B2
(en)
|
2014-01-23 |
2020-03-31 |
Boehringer Ingelheim Vetmedica Gmbh |
Treatment of metabolic disorders in canine animals
|
CN105001213B
(zh)
*
|
2014-04-14 |
2020-08-28 |
上海迪诺医药科技有限公司 |
C-芳基糖苷衍生物、其药物组合物、制备方法及应用
|
EP2944311A1
(de)
|
2014-05-16 |
2015-11-18 |
BioActive Food GmbH |
Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen
|
WO2016089872A1
(en)
|
2014-12-03 |
2016-06-09 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
CN104478967A
(zh)
*
|
2015-01-14 |
2015-04-01 |
佛山市赛维斯医药科技有限公司 |
含腈基苯噻唑基的o-半乳糖苷衍生物、其制备方法和用途
|
CN104497068A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
一种含三氟甲氧基苯s-葡萄糖苷结构的化合物及其用途
|
CN104497073A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
含丙烯腈和烷氧苯基o-葡萄糖苷结构的衍生物和用途
|
CN104497071A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
一种含丙烯腈基和腈基苯o-葡萄糖苷结构化合物及用途
|
CN104497072A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
含丙烯腈和卤代苯o-葡萄糖苷结构衍生物、其制备方法和用途
|
CN104497074A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
一种含丙烯腈基和硝基苯o-葡萄糖苷结构化合物及用途
|
CN104478961A
(zh)
*
|
2015-01-15 |
2015-04-01 |
佛山市赛维斯医药科技有限公司 |
含丙烯腈和胺基苯o-葡萄糖苷结构衍生物、其制备方法和用途
|
CN104497069A
(zh)
*
|
2015-01-15 |
2015-04-08 |
佛山市赛维斯医药科技有限公司 |
一类胺基苯基s-葡萄糖苷衍生物、其制备方法和用途
|
US20170071970A1
(en)
|
2015-09-15 |
2017-03-16 |
Janssen Pharmaceutica Nv |
Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
|
US11045485B2
(en)
|
2016-01-22 |
2021-06-29 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of PA-IL and PA-IIL lectins
|
WO2017151708A1
(en)
|
2016-03-02 |
2017-09-08 |
Glycomimetics, Inc. |
Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin
|
WO2018031445A1
(en)
|
2016-08-08 |
2018-02-15 |
Glycomimetics, Inc. |
Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4
|
WO2018068010A1
(en)
|
2016-10-07 |
2018-04-12 |
Glycomimetics, Inc. |
Highly potent multimeric e-selectin antagonists
|
EP3596096A1
(en)
|
2017-03-15 |
2020-01-22 |
GlycoMimetics, Inc. |
Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists
|
WO2019108750A1
(en)
|
2017-11-30 |
2019-06-06 |
Glycomimetics, Inc. |
Methods of mobilizing marrow infiltrating lymphocytes and uses thereof
|
JP7304863B2
(ja)
|
2017-12-29 |
2023-07-07 |
グリコミメティクス, インコーポレイテッド |
E-セレクチンおよびガレクチン-3のヘテロ二機能性阻害剤
|
CA3091454A1
(en)
|
2018-03-05 |
2019-09-12 |
Glycomimetics, Inc. |
Methods for treating acute myeloid leukemia and related conditions
|
CA3103424A1
(en)
*
|
2018-06-14 |
2019-12-19 |
Astrazeneca Uk Limited |
Methods for lowering blood sugar with a gliflozin sodium-glucose cotransporter 2 inhibitor pharmaceutical composition
|
MX2021000601A
(es)
|
2018-07-19 |
2021-04-13 |
Astrazeneca Ab |
Metodos de tratamiento de hfpef empleando dapagliflozina y composiciones que comprenden la misma.
|
CN109456370A
(zh)
*
|
2018-12-24 |
2019-03-12 |
重庆理工大学 |
一种钠-葡萄糖协同转运蛋白2抑制剂及其应用
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|
US20220023252A1
(en)
|
2020-07-27 |
2022-01-27 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
EP4315350A1
(en)
|
2021-04-01 |
2024-02-07 |
AstraZeneca UK Limited |
Systems and methods for managing prediabetes with a gliflozin sodium-glucose cotransport 2 inhibitor pharmaceutical composition
|
CN113980071B
(zh)
*
|
2021-11-26 |
2023-08-22 |
重庆大学 |
红景天苷衍生物及其应用
|
WO2023144722A1
(en)
|
2022-01-26 |
2023-08-03 |
Astrazeneca Ab |
Dapagliflozin for use in the treatment of prediabetes or reducing the risk of developing type 2 diabetes
|
CN114933619B
(zh)
*
|
2022-05-18 |
2024-03-01 |
上海科利生物医药有限公司 |
一类硫代糖苷列净类似物及其制备方法和应用
|
WO2024033288A1
(en)
*
|
2022-08-12 |
2024-02-15 |
Société des Produits Nestlé S.A. |
Salicin derivatives as inhibitors of sglt2
|