PL354784A1 - Alkileno-diamino podstawione heterocykle - Google Patents

Alkileno-diamino podstawione heterocykle

Info

Publication number
PL354784A1
PL354784A1 PL00354784A PL35478400A PL354784A1 PL 354784 A1 PL354784 A1 PL 354784A1 PL 00354784 A PL00354784 A PL 00354784A PL 35478400 A PL35478400 A PL 35478400A PL 354784 A1 PL354784 A1 PL 354784A1
Authority
PL
Poland
Prior art keywords
alkylene diamine
substituted heterocycles
certain alkylene
certain
novel compounds
Prior art date
Application number
PL00354784A
Other languages
English (en)
Inventor
Raymond F. Horvath
Jennifer Tran
Lombaert Stephane De
Kevin Julian Hodgetts
David Andrew Griffith
Philip Albert Carpino
Original Assignee
Neurogen Corporation
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corporation, Pfizer Inc. filed Critical Neurogen Corporation
Publication of PL354784A1 publication Critical patent/PL354784A1/pl

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
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    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
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    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • C—CHEMISTRY; METALLURGY
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
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  • Organic Chemistry (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL00354784A 1999-09-30 2000-09-29 Alkileno-diamino podstawione heterocykle PL354784A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15687099P 1999-09-30 1999-09-30
PCT/US2000/026886 WO2001023389A2 (en) 1999-09-30 2000-09-29 Certain alkylene diamine-substituted heterocycles

Publications (1)

Publication Number Publication Date
PL354784A1 true PL354784A1 (pl) 2004-02-23

Family

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PL00354784A PL354784A1 (pl) 1999-09-30 2000-09-29 Alkileno-diamino podstawione heterocykle

Country Status (21)

Country Link
US (3) US6506762B1 (pl)
EP (1) EP1224187B1 (pl)
JP (2) JP2003510327A (pl)
KR (1) KR20020043223A (pl)
CN (1) CN1377356A (pl)
AT (1) ATE318267T1 (pl)
AU (1) AU7738000A (pl)
BG (1) BG106508A (pl)
CA (1) CA2379640C (pl)
CZ (1) CZ20021086A3 (pl)
DE (1) DE60026155T2 (pl)
EA (1) EA200200424A1 (pl)
ES (1) ES2258476T3 (pl)
HU (1) HUP0202636A3 (pl)
IL (1) IL148903A0 (pl)
NO (1) NO20021358L (pl)
NZ (1) NZ517575A (pl)
OA (1) OA12050A (pl)
PL (1) PL354784A1 (pl)
WO (1) WO2001023389A2 (pl)
ZA (1) ZA200202518B (pl)

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WO2001023389A3 (en) 2002-05-10
OA12050A (en) 2006-05-02
BG106508A (en) 2003-02-28
WO2001023389A2 (en) 2001-04-05
EP1224187A2 (en) 2002-07-24
CZ20021086A3 (cs) 2002-10-16
EP1224187B1 (en) 2006-02-22
JP2003510327A (ja) 2003-03-18
CN1377356A (zh) 2002-10-30
KR20020043223A (ko) 2002-06-08
EA200200424A1 (ru) 2002-12-26
ES2258476T3 (es) 2006-09-01
US6506762B1 (en) 2003-01-14
HUP0202636A2 (hu) 2002-12-28
US6696445B2 (en) 2004-02-24
JP2008007515A (ja) 2008-01-17
US7074929B2 (en) 2006-07-11
NZ517575A (en) 2004-04-30
NO20021358D0 (no) 2002-03-19
CA2379640C (en) 2006-11-28
HUP0202636A3 (en) 2004-06-28
US20040229870A1 (en) 2004-11-18
NO20021358L (no) 2002-05-27
IL148903A0 (en) 2002-09-12
ZA200202518B (en) 2003-08-27
ATE318267T1 (de) 2006-03-15
AU7738000A (en) 2001-04-30
DE60026155T2 (de) 2006-08-10
US20030158197A1 (en) 2003-08-21
CA2379640A1 (en) 2001-04-05

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