ATE318267T1 - Einige alkylendiamin-substituierte heterocyclen - Google Patents
Einige alkylendiamin-substituierte heterocyclenInfo
- Publication number
- ATE318267T1 ATE318267T1 AT00967133T AT00967133T ATE318267T1 AT E318267 T1 ATE318267 T1 AT E318267T1 AT 00967133 T AT00967133 T AT 00967133T AT 00967133 T AT00967133 T AT 00967133T AT E318267 T1 ATE318267 T1 AT E318267T1
- Authority
- AT
- Austria
- Prior art keywords
- alkylenediamine
- substituted heterocycles
- novel compounds
- heterocycles
- substituted
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/5755—Neuropeptide Y
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70571—Assays involving receptors, cell surface antigens or cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15687099P | 1999-09-30 | 1999-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE318267T1 true ATE318267T1 (de) | 2006-03-15 |
Family
ID=22561438
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00967133T ATE318267T1 (de) | 1999-09-30 | 2000-09-29 | Einige alkylendiamin-substituierte heterocyclen |
Country Status (21)
Country | Link |
---|---|
US (3) | US6506762B1 (de) |
EP (1) | EP1224187B1 (de) |
JP (2) | JP2003510327A (de) |
KR (1) | KR20020043223A (de) |
CN (1) | CN1377356A (de) |
AT (1) | ATE318267T1 (de) |
AU (1) | AU7738000A (de) |
BG (1) | BG106508A (de) |
CA (1) | CA2379640C (de) |
CZ (1) | CZ20021086A3 (de) |
DE (1) | DE60026155T2 (de) |
EA (1) | EA200200424A1 (de) |
ES (1) | ES2258476T3 (de) |
HU (1) | HUP0202636A3 (de) |
IL (1) | IL148903A0 (de) |
NO (1) | NO20021358L (de) |
NZ (1) | NZ517575A (de) |
OA (1) | OA12050A (de) |
PL (1) | PL354784A1 (de) |
WO (1) | WO2001023389A2 (de) |
ZA (1) | ZA200202518B (de) |
Families Citing this family (150)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1183245T3 (da) * | 1999-04-22 | 2007-09-24 | Lundbeck & Co As H | Selektive NPY(Y5)-antagonister |
US6989379B1 (en) | 1999-04-22 | 2006-01-24 | H. Lundbick A/S | Selective NPY (Y5) antagonists |
US6340683B1 (en) | 1999-04-22 | 2002-01-22 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (triazines) |
US7273880B2 (en) | 1999-06-30 | 2007-09-25 | H. Lunbeck A/S | Selective NPY (Y5) antagonists |
HUP0202678A3 (en) * | 1999-09-30 | 2004-06-28 | Pfizer | Certain alkylene diamine-substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines, pharmaceutical compositions containing them and their use |
EA200200424A1 (ru) * | 1999-09-30 | 2002-12-26 | Ньюроджен Корпорейшн | Некоторые гетероциклы, замещенные алкилендиамином |
WO2001055103A2 (en) * | 2000-01-28 | 2001-08-02 | Neurogen Corporation | Chimeric neuropeptide y receptors |
EE200200711A (et) * | 2000-06-26 | 2004-06-15 | Pfizer Products Inc. | Pürrolo[2,3-d]pürimidiinühendid kui immunosupressiivsed vahendid |
MXPA03004245A (es) * | 2000-12-12 | 2003-09-22 | Neurogen Corp | Espiro[isobenzofuran-1,4'piperidin]-3-onas y 3h-espiroisobenzofuran-1,4'-piperidinas. |
CN1649848A (zh) | 2001-04-30 | 2005-08-03 | 葛兰素集团有限公司 | 作为促肾上腺皮质激素释放因子(crf)拮抗剂的稠合嘧啶衍生物 |
MXPA03009925A (es) * | 2001-04-30 | 2004-06-30 | Bayer Pharmaceuticals Corp | Nuevas tiofeno [2,3-d]pirimidinas 4-amino-5,6-sustituidas. |
US7498019B2 (en) | 2001-05-24 | 2009-03-03 | Alexza Pharmaceuticals, Inc. | Delivery of compounds for the treatment of headache through an inhalation route |
US6805853B2 (en) * | 2001-11-09 | 2004-10-19 | Alexza Molecular Delivery Corporation | Delivery of diazepam through an inhalation route |
US7090830B2 (en) * | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
US20030051728A1 (en) * | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
EP1392258B1 (de) * | 2001-05-24 | 2008-11-26 | Alexza Pharmaceuticals, Inc. | Verabreichung von alprazolam, estazolam, midazolam oder triazolam durch inhalation |
US20070122353A1 (en) * | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US6759029B2 (en) * | 2001-05-24 | 2004-07-06 | Alexza Molecular Delivery Corporation | Delivery of rizatriptan and zolmitriptan through an inhalation route |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
JP2005503425A (ja) | 2001-05-24 | 2005-02-03 | アレックザ モレキュラー デリヴァリー コーポレイション | 所定の吸入ルートによる薬剤エステルの送出 |
US7458374B2 (en) * | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
GB0117396D0 (en) | 2001-07-17 | 2001-09-05 | Glaxo Group Ltd | Chemical compounds |
US7323469B2 (en) | 2001-08-07 | 2008-01-29 | Novartis Ag | 7H-pyrrolo[2,3-d]pyrimidine derivatives |
GB0119249D0 (en) | 2001-08-07 | 2001-10-03 | Novartis Ag | Organic compounds |
US6787558B2 (en) * | 2001-09-28 | 2004-09-07 | Hoffmann-La Roche Inc. | Quinoline derivatives |
CA2403307A1 (en) | 2001-10-23 | 2003-04-23 | Neurogen Corporation | Substituted 2-cyclohexyl-4-phenyl-1h-imidazole derivatives |
AU2002363947A1 (en) * | 2001-11-21 | 2003-07-24 | Alexza Molecular Delivery Corporation | Delivery of caffeine through an inhalation route |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
WO2003094900A1 (en) | 2002-05-13 | 2003-11-20 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
US20060193788A1 (en) * | 2002-11-26 | 2006-08-31 | Hale Ron L | Acute treatment of headache with phenothiazine antipsychotics |
EP1522314B1 (de) * | 2002-06-26 | 2014-03-05 | Ono Pharmaceutical Co., Ltd. | Arzneimittel für durch vaskuläre kontraktion oder dilatation hervorgerufene erkrankungen |
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NZ524842A (en) * | 1998-01-28 | 2003-10-31 | Bristol Myers Squibb Pharma Co | Azolo triazines and pyrimidines |
US6187777B1 (en) * | 1998-02-06 | 2001-02-13 | Amgen Inc. | Compounds and methods which modulate feeding behavior and related diseases |
AU2931099A (en) * | 1998-03-06 | 1999-09-20 | Janssen Pharmaceutica N.V. | Crf antagonistic pyrazolo(4,3-b)pyridines |
HUP0202678A3 (en) * | 1999-09-30 | 2004-06-28 | Pfizer | Certain alkylene diamine-substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines, pharmaceutical compositions containing them and their use |
EA200200424A1 (ru) * | 1999-09-30 | 2002-12-26 | Ньюроджен Корпорейшн | Некоторые гетероциклы, замещенные алкилендиамином |
WO2001055103A2 (en) | 2000-01-28 | 2001-08-02 | Neurogen Corporation | Chimeric neuropeptide y receptors |
MXPA03004245A (es) * | 2000-12-12 | 2003-09-22 | Neurogen Corp | Espiro[isobenzofuran-1,4'piperidin]-3-onas y 3h-espiroisobenzofuran-1,4'-piperidinas. |
CA2403307A1 (en) * | 2001-10-23 | 2003-04-23 | Neurogen Corporation | Substituted 2-cyclohexyl-4-phenyl-1h-imidazole derivatives |
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2000
- 2000-09-29 EA EA200200424A patent/EA200200424A1/ru unknown
- 2000-09-29 CN CN00813704A patent/CN1377356A/zh active Pending
- 2000-09-29 AT AT00967133T patent/ATE318267T1/de not_active IP Right Cessation
- 2000-09-29 OA OA1200200089A patent/OA12050A/en unknown
- 2000-09-29 AU AU77380/00A patent/AU7738000A/en not_active Abandoned
- 2000-09-29 NZ NZ517575A patent/NZ517575A/en unknown
- 2000-09-29 IL IL14890300A patent/IL148903A0/xx unknown
- 2000-09-29 ES ES00967133T patent/ES2258476T3/es not_active Expired - Lifetime
- 2000-09-29 CZ CZ20021086A patent/CZ20021086A3/cs unknown
- 2000-09-29 EP EP00967133A patent/EP1224187B1/de not_active Expired - Lifetime
- 2000-09-29 PL PL00354784A patent/PL354784A1/xx not_active Application Discontinuation
- 2000-09-29 KR KR1020027004150A patent/KR20020043223A/ko not_active Application Discontinuation
- 2000-09-29 WO PCT/US2000/026886 patent/WO2001023389A2/en active IP Right Grant
- 2000-09-29 DE DE60026155T patent/DE60026155T2/de not_active Expired - Fee Related
- 2000-09-29 HU HU0202636A patent/HUP0202636A3/hu unknown
- 2000-09-29 JP JP2001526541A patent/JP2003510327A/ja active Pending
- 2000-09-29 CA CA002379640A patent/CA2379640C/en not_active Expired - Fee Related
- 2000-09-29 US US09/676,941 patent/US6506762B1/en not_active Expired - Fee Related
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2002
- 2002-03-11 BG BG106508A patent/BG106508A/xx unknown
- 2002-03-19 NO NO20021358A patent/NO20021358L/no not_active Application Discontinuation
- 2002-03-28 ZA ZA200202518A patent/ZA200202518B/xx unknown
- 2002-11-08 US US10/291,446 patent/US6696445B2/en not_active Expired - Fee Related
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2003
- 2003-11-10 US US10/705,446 patent/US7074929B2/en not_active Expired - Fee Related
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2007
- 2007-08-22 JP JP2007215782A patent/JP2008007515A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU7738000A (en) | 2001-04-30 |
NO20021358L (no) | 2002-05-27 |
WO2001023389A2 (en) | 2001-04-05 |
EA200200424A1 (ru) | 2002-12-26 |
HUP0202636A3 (en) | 2004-06-28 |
US20040229870A1 (en) | 2004-11-18 |
ES2258476T3 (es) | 2006-09-01 |
NO20021358D0 (no) | 2002-03-19 |
CA2379640A1 (en) | 2001-04-05 |
JP2008007515A (ja) | 2008-01-17 |
ZA200202518B (en) | 2003-08-27 |
US6696445B2 (en) | 2004-02-24 |
EP1224187A2 (de) | 2002-07-24 |
PL354784A1 (en) | 2004-02-23 |
DE60026155T2 (de) | 2006-08-10 |
US6506762B1 (en) | 2003-01-14 |
IL148903A0 (en) | 2002-09-12 |
CZ20021086A3 (cs) | 2002-10-16 |
OA12050A (en) | 2006-05-02 |
CN1377356A (zh) | 2002-10-30 |
WO2001023389A3 (en) | 2002-05-10 |
BG106508A (en) | 2003-02-28 |
JP2003510327A (ja) | 2003-03-18 |
DE60026155D1 (de) | 2006-04-27 |
EP1224187B1 (de) | 2006-02-22 |
HUP0202636A2 (hu) | 2002-12-28 |
KR20020043223A (ko) | 2002-06-08 |
US20030158197A1 (en) | 2003-08-21 |
NZ517575A (en) | 2004-04-30 |
US7074929B2 (en) | 2006-07-11 |
CA2379640C (en) | 2006-11-28 |
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