PL2616069T3 - Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu - Google Patents

Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu

Info

Publication number
PL2616069T3
PL2616069T3 PL11760963T PL11760963T PL2616069T3 PL 2616069 T3 PL2616069 T3 PL 2616069T3 PL 11760963 T PL11760963 T PL 11760963T PL 11760963 T PL11760963 T PL 11760963T PL 2616069 T3 PL2616069 T3 PL 2616069T3
Authority
PL
Poland
Prior art keywords
imidazol
methylphenyl
drugs
methanol
ethyl
Prior art date
Application number
PL11760963T
Other languages
English (en)
Inventor
Ken Chow
Mohammed I. Dibas
John E. Donello
Michael E. Garst
Daniel W. Gil
Liming Wang
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44675870&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2616069(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Publication of PL2616069T3 publication Critical patent/PL2616069T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL11760963T 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu PL2616069T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38337010P 2010-09-16 2010-09-16
EP11760963.6A EP2616069B1 (en) 2010-09-16 2011-09-16 Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl]methanol

Publications (1)

Publication Number Publication Date
PL2616069T3 true PL2616069T3 (pl) 2017-04-28

Family

ID=44675870

Family Applications (7)

Application Number Title Priority Date Filing Date
PL16161920T PL3050563T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1 h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do leczenia chorób skóry i stanów skórnych
PL16161923T PL3050564T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu
PL16161922T PL3053576T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do obniżania ciśnienia śródgałkowego
PL18157147T PL3338777T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu do leczenia chorób siatkówki
PL18160174T PL3348264T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego
PL11760963T PL2616069T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu
PL11760962.8T PL2616068T3 (pl) 2010-09-16 2011-09-16 Proleki estrów pochodzących z [3-(1-(1h-imidazol-4-ilo)etylo)-2- metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Family Applications Before (5)

Application Number Title Priority Date Filing Date
PL16161920T PL3050563T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1 h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do leczenia chorób skóry i stanów skórnych
PL16161923T PL3050564T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu
PL16161922T PL3053576T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do obniżania ciśnienia śródgałkowego
PL18157147T PL3338777T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu do leczenia chorób siatkówki
PL18160174T PL3348264T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11760962.8T PL2616068T3 (pl) 2010-09-16 2011-09-16 Proleki estrów pochodzących z [3-(1-(1h-imidazol-4-ilo)etylo)-2- metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Country Status (29)

Country Link
US (9) US8501796B2 (pl)
EP (13) EP3053576B1 (pl)
JP (4) JP2013541527A (pl)
KR (7) KR102354097B1 (pl)
CN (5) CN105412092B (pl)
AR (4) AR083019A1 (pl)
AU (4) AU2011301932C1 (pl)
BR (4) BR112013006355A2 (pl)
CA (8) CA2812197C (pl)
CL (4) CL2013000736A1 (pl)
CY (3) CY1121024T1 (pl)
DK (9) DK3053576T3 (pl)
ES (10) ES2904479T3 (pl)
HK (5) HK1185538A1 (pl)
HU (5) HUE049573T2 (pl)
IL (4) IL225280A0 (pl)
MX (4) MX2013003002A (pl)
MY (4) MY191369A (pl)
NZ (1) NZ608751A (pl)
PL (7) PL3050563T3 (pl)
PT (7) PT2616069T (pl)
RU (4) RU2013116405A (pl)
SG (4) SG188570A1 (pl)
SI (5) SI3338777T1 (pl)
TR (1) TR201909249T4 (pl)
TW (4) TWI591058B (pl)
UA (1) UA112973C2 (pl)
WO (4) WO2012037499A1 (pl)
ZA (4) ZA201302193B (pl)

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DK3566703T3 (da) * 2009-02-13 2021-07-05 Allergan Inc Farmaceutiske sammensætninger omfattende (3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl)methanol
AU2011203867B2 (en) 2010-01-11 2015-12-03 Nalpropion Pharmaceuticals Llc Methods of providing weight loss therapy in patients with major depression
US8501796B2 (en) * 2010-09-16 2013-08-06 Allergan, Inc. Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
BR112014001501A2 (pt) * 2011-07-22 2017-02-14 Allergan Inc moduladores alfa-2 adrenérgicos para tratamento de distúrbios visuais mediados por projeções visuais centrais do olho
WO2013078151A1 (en) 2011-11-21 2013-05-30 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole derivatives for treating retinal diseases
USD794650S1 (en) 2014-11-28 2017-08-15 Samsung Electronics Co., Ltd. Display screen or portion thereof with a graphical user interface
CN108310442B (zh) * 2017-01-17 2021-08-27 台北科技大学 眼科用组合物
KR102050506B1 (ko) 2017-06-20 2019-11-29 한국식품연구원 망막 질환 예방, 개선, 완화 또는 치료용 조성물
CN108872431B (zh) * 2018-07-09 2021-03-23 成都倍特药业股份有限公司 一种检测4-(1-(2,5-二甲基苯基)乙基)-1h-咪唑或/和其盐酸盐的方法
WO2020038387A1 (zh) * 2018-08-24 2020-02-27 杭州阿诺生物医药科技有限公司 高活性sting蛋白激动剂
BR112023021140A2 (pt) * 2021-04-16 2023-12-12 Ads Therapeutics Llc Cofármaco compreendendo uma fração de agonista muscarínico e uma fração de agonista alfa2 adrenérgico, ou um sal farmacêutico deste, composição farmacêutica e formulação farmacêutica

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BR112013006320B1 (pt) 2022-08-30
EP3050564A1 (en) 2016-08-03
EP2616068A1 (en) 2013-07-24
AU2011301856A1 (en) 2013-05-02
KR101952457B1 (ko) 2019-02-26
US20120149746A1 (en) 2012-06-14
US20150148394A1 (en) 2015-05-28
CY1121024T1 (el) 2019-12-11
AU2011301847A1 (en) 2013-05-02
EP3636263A1 (en) 2020-04-15
AR083019A1 (es) 2013-01-23
DK3348264T3 (da) 2020-03-23
CA3122745A1 (en) 2012-03-22
AU2011301856C1 (en) 2016-09-08
EP3348264B1 (en) 2020-01-01
US8492422B2 (en) 2013-07-23
EP3050563A1 (en) 2016-08-03
CA2812191A1 (en) 2012-03-22
EP2616066A1 (en) 2013-07-24
JP2013540749A (ja) 2013-11-07
BR112013006320A2 (pt) 2016-06-21
KR20140005154A (ko) 2014-01-14
AR083020A1 (es) 2013-01-23
SI3050564T1 (sl) 2020-02-28
US20160354346A1 (en) 2016-12-08
JP2013541527A (ja) 2013-11-14
WO2012037453A1 (en) 2012-03-22
CA2812195A1 (en) 2012-03-22
TW201240661A (en) 2012-10-16
EP2616067B1 (en) 2016-05-18
WO2012037490A1 (en) 2012-03-22
HK1185538A1 (zh) 2014-02-21
BR112013006362A2 (pt) 2016-06-28
ES2593612T3 (es) 2016-12-12
AU2011301901B2 (en) 2016-02-11
EP3659600A1 (en) 2020-06-03
ES2613509T3 (es) 2017-05-24
IL225278A (en) 2015-11-30
DK3050563T3 (en) 2018-08-13
CL2013000733A1 (es) 2013-08-23
PL3050564T3 (pl) 2020-06-01
PT3338777T (pt) 2020-05-06
MX2013003009A (es) 2013-06-28
RU2013116763A (ru) 2014-10-27
CY1122958T1 (el) 2021-10-29
MY168763A (en) 2018-12-04
EP3053576A1 (en) 2016-08-10
ZA201302291B (en) 2013-11-27
PT2616068T (pt) 2016-09-13
AR083018A1 (es) 2013-01-23
US20130289088A1 (en) 2013-10-31
TW201305116A (zh) 2013-02-01
EP3698789A1 (en) 2020-08-26
EP3348264A1 (en) 2018-07-18
TW201240662A (en) 2012-10-16
HK1257416A1 (zh) 2019-10-18
US20140057958A1 (en) 2014-02-27
AR083017A1 (es) 2013-01-23
PT3050564T (pt) 2019-12-11
AU2011301847B2 (en) 2016-02-11
SG188570A1 (en) 2013-04-30
PL3338777T3 (pl) 2020-07-13
PT3348264T (pt) 2020-04-02
CA2811559A1 (en) 2012-03-22
CL2013000735A1 (es) 2013-11-29
DK3636263T3 (da) 2022-01-10
IL225278A0 (en) 2013-06-27
SI3348264T1 (sl) 2020-07-31
DK3338777T3 (da) 2020-04-20
ES2904479T3 (es) 2022-04-05
US20120142746A1 (en) 2012-06-07
RU2013116541A (ru) 2014-10-27
PL2616068T3 (pl) 2016-11-30
ZA201302288B (en) 2013-11-27
ES2760920T3 (es) 2020-05-18
US8653123B2 (en) 2014-02-18
SG188571A1 (en) 2013-04-30
CY1122809T1 (el) 2021-05-05
CA2812197C (en) 2024-01-02
AU2011301901A1 (en) 2013-05-02
US8492557B2 (en) 2013-07-23
RU2612351C2 (ru) 2017-03-07
KR20130114140A (ko) 2013-10-16
EP3050563B1 (en) 2018-05-09
MX2013003002A (es) 2013-06-28
PL3050563T3 (pl) 2018-12-31
ES2788051T3 (es) 2020-10-20
JP6045495B2 (ja) 2016-12-14
MY161607A (en) 2017-04-28
SG188572A1 (en) 2013-04-30
RU2013116405A (ru) 2014-10-27
WO2012037484A1 (en) 2012-03-22
CA3079450A1 (en) 2012-03-22
CA3116249A1 (en) 2012-03-22
CN105412092A (zh) 2016-03-23
MY191369A (en) 2022-06-20
TWI591058B (zh) 2017-07-11
DK2616068T3 (en) 2016-08-29
EP3050564B1 (en) 2019-09-04
MX2013003004A (es) 2013-06-28
CA2812191C (en) 2021-04-13
CN103200942A (zh) 2013-07-10
NZ608751A (en) 2015-04-24
AU2011301932A1 (en) 2013-05-02
HK1185539A1 (zh) 2014-02-21
PL3053576T3 (pl) 2018-11-30
IL225280A0 (en) 2013-06-27
CL2013000736A1 (es) 2013-07-12
ZA201302193B (en) 2013-11-27
ES2781681T3 (es) 2020-09-04
EP2616068B1 (en) 2016-07-13
HK1185540A1 (zh) 2014-02-21
ES2687420T3 (es) 2018-10-25
US8501796B2 (en) 2013-08-06
CL2013000734A1 (es) 2013-11-08
ES2737230T3 (es) 2020-01-10
CA3077732A1 (en) 2012-03-22
AU2011301932C1 (en) 2016-09-01
AU2011301932B2 (en) 2016-02-25
WO2012037499A1 (en) 2012-03-22
US20130296394A1 (en) 2013-11-07
KR101840500B1 (ko) 2018-03-20
KR20140003407A (ko) 2014-01-09
EP2616069B1 (en) 2016-11-16
CN105412092B (zh) 2020-11-17
US8853251B2 (en) 2014-10-07
HUE039090T2 (hu) 2018-12-28
EP3078376B1 (en) 2019-03-27
PT3050563T (pt) 2018-10-01
CN103200941A (zh) 2013-07-10
ES2684055T3 (es) 2018-10-01
KR20200091507A (ko) 2020-07-30
EP3636263B1 (en) 2021-11-03
MY173846A (en) 2020-02-24
IL225281A0 (en) 2013-06-27
JP2013537237A (ja) 2013-09-30
UA112973C2 (uk) 2016-11-25
EP3338777A1 (en) 2018-06-27
KR101840501B1 (ko) 2018-05-04
TW201305117A (zh) 2013-02-01
EP3338777B1 (en) 2020-02-05
DK3053576T3 (en) 2018-08-20
KR20200044147A (ko) 2020-04-28
HUE047476T2 (hu) 2020-04-28
SI3053576T1 (sl) 2018-11-30
KR102139905B1 (ko) 2020-07-31
CA2812197A1 (en) 2012-03-22
TR201909249T4 (tr) 2019-07-22
HUE048725T2 (hu) 2020-09-28
BR112013006352A2 (pt) 2016-06-28
IL225282A0 (en) 2013-06-27
ZA201302194B (en) 2013-11-27
EP3053576B1 (en) 2018-05-16
US20120136036A1 (en) 2012-05-31
JP6073229B2 (ja) 2017-02-01
PT2616069T (pt) 2016-12-06
MX2013003008A (es) 2013-06-28
CN103209694A (zh) 2013-07-17
DK3050564T3 (da) 2019-11-25
PT3053576T (pt) 2018-10-08
HUE049573T2 (hu) 2020-10-28
RU2013116403A (ru) 2014-10-27
KR20190022895A (ko) 2019-03-06
KR102354097B1 (ko) 2022-01-20
SG188573A1 (en) 2013-04-30
KR20130105658A (ko) 2013-09-25
DK3078376T3 (da) 2019-06-24
JP2013537236A (ja) 2013-09-30
EP3078376A1 (en) 2016-10-12
SI3338777T1 (sl) 2020-08-31
CN103221045A (zh) 2013-07-24
EP2616069A1 (en) 2013-07-24
HUE038698T2 (hu) 2018-11-28
EP2616066B1 (en) 2016-07-13
EP2616067A1 (en) 2013-07-24
SI3050563T1 (sl) 2018-10-30
US20120122945A1 (en) 2012-05-17
BR112013006355A2 (pt) 2016-06-28
KR102104760B1 (ko) 2020-04-27
HK1185541A1 (zh) 2014-02-21
PL3348264T3 (pl) 2020-08-24
DK2616069T3 (en) 2016-12-19
CN103200941B (zh) 2015-12-16
ES2607084T3 (es) 2017-03-29

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