PL3348264T3 - Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego - Google Patents

Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Info

Publication number
PL3348264T3
PL3348264T3 PL18160174T PL18160174T PL3348264T3 PL 3348264 T3 PL3348264 T3 PL 3348264T3 PL 18160174 T PL18160174 T PL 18160174T PL 18160174 T PL18160174 T PL 18160174T PL 3348264 T3 PL3348264 T3 PL 3348264T3
Authority
PL
Poland
Prior art keywords
imidazol
methylphenyl
drugs
methanol
ethyl
Prior art date
Application number
PL18160174T
Other languages
English (en)
Inventor
Mohammed I. Dibas
Ken Chow
John E. Donello
Michael E. Garst
Daniel W. Gil
Liming Wang
Original Assignee
Allergan, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44675870&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3348264(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan, Inc. filed Critical Allergan, Inc.
Publication of PL3348264T3 publication Critical patent/PL3348264T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL18160174T 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego PL3348264T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38337010P 2010-09-16 2010-09-16
PCT/US2011/051990 WO2012037490A1 (en) 2010-09-16 2011-09-16 Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
EP16161922.6A EP3053576B1 (en) 2010-09-16 2011-09-16 Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure
EP11760962.8A EP2616068B1 (en) 2010-09-16 2011-09-16 Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl]methanol for lowering intraocular pressure
EP18160174.1A EP3348264B1 (en) 2010-09-16 2011-09-16 Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for lowering intraocular pressure

Publications (1)

Publication Number Publication Date
PL3348264T3 true PL3348264T3 (pl) 2020-08-24

Family

ID=44675870

Family Applications (7)

Application Number Title Priority Date Filing Date
PL16161920T PL3050563T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1 h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do leczenia chorób skóry i stanów skórnych
PL16161923T PL3050564T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu
PL16161922T PL3053576T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do obniżania ciśnienia śródgałkowego
PL18160174T PL3348264T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)- 2-metylofenylo]metanolu do obniżania ciśnienia śródgałkowego
PL18157147T PL3338777T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu do leczenia chorób siatkówki
PL11760963T PL2616069T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu
PL11760962.8T PL2616068T3 (pl) 2010-09-16 2011-09-16 Proleki estrów pochodzących z [3-(1-(1h-imidazol-4-ilo)etylo)-2- metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Family Applications Before (3)

Application Number Title Priority Date Filing Date
PL16161920T PL3050563T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1 h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do leczenia chorób skóry i stanów skórnych
PL16161923T PL3050564T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu
PL16161922T PL3053576T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo] metanolu do obniżania ciśnienia śródgałkowego

Family Applications After (3)

Application Number Title Priority Date Filing Date
PL18157147T PL3338777T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazol-4-ilo)etylo)-2-metylofenylo]metanolu do leczenia chorób siatkówki
PL11760963T PL2616069T3 (pl) 2010-09-16 2011-09-16 Estrowe proleki [3-(1-(1h-imidazolo-4-ilo)etylo)-2-metylofenylo]metanolu
PL11760962.8T PL2616068T3 (pl) 2010-09-16 2011-09-16 Proleki estrów pochodzących z [3-(1-(1h-imidazol-4-ilo)etylo)-2- metylofenylo]metanolu do obniżania ciśnienia śródgałkowego

Country Status (28)

Country Link
US (9) US8653123B2 (pl)
EP (13) EP3338777B1 (pl)
JP (4) JP6045495B2 (pl)
KR (7) KR102354097B1 (pl)
CN (5) CN103221045A (pl)
AR (4) AR083017A1 (pl)
AU (4) AU2011301901B2 (pl)
BR (4) BR112013006352A2 (pl)
CA (8) CA2811559A1 (pl)
CL (4) CL2013000734A1 (pl)
CY (3) CY1121024T1 (pl)
DK (9) DK2616068T3 (pl)
ES (10) ES2904479T3 (pl)
HU (5) HUE039090T2 (pl)
IL (4) IL225281A0 (pl)
MX (4) MX2013003002A (pl)
MY (4) MY168763A (pl)
NZ (1) NZ608751A (pl)
PL (7) PL3050563T3 (pl)
PT (7) PT2616069T (pl)
RU (4) RU2013116405A (pl)
SG (4) SG188573A1 (pl)
SI (5) SI3050563T1 (pl)
TR (1) TR201909249T4 (pl)
TW (4) TW201240661A (pl)
UA (1) UA112973C2 (pl)
WO (4) WO2012037484A1 (pl)
ZA (4) ZA201302194B (pl)

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CA2785822C (en) 2010-01-11 2019-06-25 Orexigen Therapeutics, Inc. Methods of providing weight loss therapy in patients with major depression
US8653123B2 (en) * 2010-09-16 2014-02-18 Allergan, Inc. Ester pro-drugs of [3-(1-(1H-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating retinal diseases
AU2012287243A1 (en) * 2011-07-22 2014-02-20 Allergan, Inc. Alpha-2 adrenergic modulators for treating visual disorders mediated by central visual projections from the eye
US9095576B2 (en) 2011-11-21 2015-08-04 Allergan, Inc. Pharmaceutical compositions comprising 4-[1-(2,3-dimethylphenyl)ethyl]-3H-imidazole derivatives for treating retinal diseases
USD794650S1 (en) 2014-11-28 2017-08-15 Samsung Electronics Co., Ltd. Display screen or portion thereof with a graphical user interface
CN108310442B (zh) * 2017-01-17 2021-08-27 台北科技大学 眼科用组合物
KR102050506B1 (ko) 2017-06-20 2019-11-29 한국식품연구원 망막 질환 예방, 개선, 완화 또는 치료용 조성물
CN108872431B (zh) * 2018-07-09 2021-03-23 成都倍特药业股份有限公司 一种检测4-(1-(2,5-二甲基苯基)乙基)-1h-咪唑或/和其盐酸盐的方法
CN112552314B (zh) * 2018-08-24 2022-03-04 杭州阿诺生物医药科技有限公司 Sting激动剂小分子抗肿瘤化合物及其应用
AU2022258105A1 (en) * 2021-04-16 2023-10-26 Ads Therapeutics Llc Alpha2 adrenergic agonist codrugs conjugated with muscarinic agonist drugs
IL322606A (en) * 2023-02-08 2025-10-01 Bausch & Lomb Ireland Ltd Alpha-2-adrenergic agonists for improving vision
WO2025179071A1 (en) * 2024-02-20 2025-08-28 Bausch + Lomb Ireland Limited Sustained-release drug delivery compositions for treating ocular diseases

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Also Published As

Publication number Publication date
CL2013000733A1 (es) 2013-08-23
CN103200941A (zh) 2013-07-10
US20140057958A1 (en) 2014-02-27
CN103221045A (zh) 2013-07-24
EP2616069A1 (en) 2013-07-24
JP6045495B2 (ja) 2016-12-14
RU2013116405A (ru) 2014-10-27
KR101840500B1 (ko) 2018-03-20
ES2687420T3 (es) 2018-10-25
US20130289088A1 (en) 2013-10-31
HK1257416A1 (en) 2019-10-18
SG188571A1 (en) 2013-04-30
TWI591058B (zh) 2017-07-11
PT3053576T (pt) 2018-10-08
PT2616069T (pt) 2016-12-06
AR083017A1 (es) 2013-01-23
BR112013006362A2 (pt) 2016-06-28
CY1122809T1 (el) 2021-05-05
PT3050564T (pt) 2019-12-11
MX2013003004A (es) 2013-06-28
MX2013003008A (es) 2013-06-28
CN103200942A (zh) 2013-07-10
AU2011301847A1 (en) 2013-05-02
HK1185541A1 (zh) 2014-02-21
EP2616069B1 (en) 2016-11-16
PT3050563T (pt) 2018-10-01
KR102104760B1 (ko) 2020-04-27
CA3079450A1 (en) 2012-03-22
EP3698789A1 (en) 2020-08-26
RU2612351C2 (ru) 2017-03-07
US8853251B2 (en) 2014-10-07
JP2013540749A (ja) 2013-11-07
HK1185538A1 (zh) 2014-02-21
CL2013000736A1 (es) 2013-07-12
EP2616066B1 (en) 2016-07-13
CL2013000734A1 (es) 2013-11-08
US8492557B2 (en) 2013-07-23
ES2684055T3 (es) 2018-10-01
IL225282A0 (en) 2013-06-27
KR20130114140A (ko) 2013-10-16
PT3338777T (pt) 2020-05-06
AU2011301901A1 (en) 2013-05-02
KR102139905B1 (ko) 2020-07-31
AU2011301932B2 (en) 2016-02-25
ZA201302288B (en) 2013-11-27
KR20200091507A (ko) 2020-07-30
KR20200044147A (ko) 2020-04-28
CA2812191C (en) 2021-04-13
DK3078376T3 (da) 2019-06-24
RU2013116403A (ru) 2014-10-27
HUE049573T2 (hu) 2020-10-28
DK2616068T3 (en) 2016-08-29
CA2811559A1 (en) 2012-03-22
IL225280A0 (en) 2013-06-27
RU2013116541A (ru) 2014-10-27
BR112013006320A2 (pt) 2016-06-21
DK3636263T3 (da) 2022-01-10
SI3348264T1 (sl) 2020-07-31
KR20130105658A (ko) 2013-09-25
RU2013116763A (ru) 2014-10-27
WO2012037453A1 (en) 2012-03-22
ES2613509T3 (es) 2017-05-24
IL225278A (en) 2015-11-30
US20160354346A1 (en) 2016-12-08
PL3053576T3 (pl) 2018-11-30
CN103209694A (zh) 2013-07-17
NZ608751A (en) 2015-04-24
CA2812191A1 (en) 2012-03-22
EP3659600A1 (en) 2020-06-03
CY1121024T1 (el) 2019-12-11
EP3348264B1 (en) 2020-01-01
CN103200941B (zh) 2015-12-16
EP3053576B1 (en) 2018-05-16
EP3338777B1 (en) 2020-02-05
AU2011301847B2 (en) 2016-02-11
ES2760920T3 (es) 2020-05-18
WO2012037484A1 (en) 2012-03-22
MX2013003002A (es) 2013-06-28
MY173846A (en) 2020-02-24
HK1185539A1 (zh) 2014-02-21
US20120122945A1 (en) 2012-05-17
AR083018A1 (es) 2013-01-23
US8492422B2 (en) 2013-07-23
MY168763A (en) 2018-12-04
DK3050563T3 (en) 2018-08-13
SG188570A1 (en) 2013-04-30
IL225281A0 (en) 2013-06-27
JP2013537237A (ja) 2013-09-30
CN105412092A (zh) 2016-03-23
EP3636263A1 (en) 2020-04-15
AU2011301856A1 (en) 2013-05-02
CA3116249A1 (en) 2012-03-22
EP3348264A1 (en) 2018-07-18
ZA201302193B (en) 2013-11-27
DK3050564T3 (da) 2019-11-25
JP2013537236A (ja) 2013-09-30
TR201909249T4 (tr) 2019-07-22
ZA201302194B (en) 2013-11-27
TW201305116A (zh) 2013-02-01
EP2616067A1 (en) 2013-07-24
KR20140003407A (ko) 2014-01-09
EP3050563B1 (en) 2018-05-09
SI3050564T1 (sl) 2020-02-28
WO2012037499A1 (en) 2012-03-22
EP3050564B1 (en) 2019-09-04
EP2616066A1 (en) 2013-07-24
ES2607084T3 (es) 2017-03-29
AR083020A1 (es) 2013-01-23
ES2788051T3 (es) 2020-10-20
CA2812197C (en) 2024-01-02
AU2011301932C1 (en) 2016-09-01
US20150148394A1 (en) 2015-05-28
HK1185540A1 (en) 2014-02-21
US20120142746A1 (en) 2012-06-07
BR112013006352A2 (pt) 2016-06-28
AR083019A1 (es) 2013-01-23
AU2011301932A1 (en) 2013-05-02
ES2593612T3 (es) 2016-12-12
MX2013003009A (es) 2013-06-28
JP2013541527A (ja) 2013-11-14
EP3050564A1 (en) 2016-08-03
HUE038698T2 (hu) 2018-11-28
KR101952457B1 (ko) 2019-02-26
PL3050563T3 (pl) 2018-12-31
CA2812195A1 (en) 2012-03-22
EP2616068B1 (en) 2016-07-13
EP3338777A1 (en) 2018-06-27
US20130296394A1 (en) 2013-11-07
DK3338777T3 (da) 2020-04-20
ES2904479T3 (es) 2022-04-05
BR112013006355A2 (pt) 2016-06-28
BR112013006320B1 (pt) 2022-08-30
TW201240662A (en) 2012-10-16
SG188572A1 (en) 2013-04-30
ES2781681T3 (es) 2020-09-04
KR20190022895A (ko) 2019-03-06
KR102354097B1 (ko) 2022-01-20
UA112973C2 (uk) 2016-11-25
DK3348264T3 (da) 2020-03-23
EP3078376A1 (en) 2016-10-12
DK3053576T3 (en) 2018-08-20
CA3077732A1 (en) 2012-03-22
PL2616068T3 (pl) 2016-11-30
JP6073229B2 (ja) 2017-02-01
US20120136036A1 (en) 2012-05-31
PT2616068T (pt) 2016-09-13
DK2616069T3 (en) 2016-12-19
PL3050564T3 (pl) 2020-06-01
IL225278A0 (en) 2013-06-27
CN105412092B (zh) 2020-11-17
HUE047476T2 (hu) 2020-04-28
EP3053576A1 (en) 2016-08-10
EP2616067B1 (en) 2016-05-18
HUE048725T2 (hu) 2020-09-28
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