PL2370474T3 - Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli - Google Patents

Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli

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Publication number
PL2370474T3
PL2370474T3 PL09795949T PL09795949T PL2370474T3 PL 2370474 T3 PL2370474 T3 PL 2370474T3 PL 09795949 T PL09795949 T PL 09795949T PL 09795949 T PL09795949 T PL 09795949T PL 2370474 T3 PL2370474 T3 PL 2370474T3
Authority
PL
Poland
Prior art keywords
hydrogels
formation
hyaluronic acid
acid functionalized
functionalized derivatives
Prior art date
Application number
PL09795949T
Other languages
English (en)
Inventor
Gaetano Giammona
Fabio Palumbo
Giovanna Pitarresi
Original Assignee
Univ Degli Studi Di Palermo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Di Palermo filed Critical Univ Degli Studi Di Palermo
Publication of PL2370474T3 publication Critical patent/PL2370474T3/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B23MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23KSOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
    • B23K9/00Arc welding or cutting
    • B23K9/10Other electric circuits therefor; Protective circuits; Remote controls

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • Plasma & Fusion (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Arc Welding Control (AREA)
PL09795949T 2008-11-28 2009-11-30 Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli PL2370474T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT000636A ITRM20080636A1 (it) 2008-11-28 2008-11-28 Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
PCT/EP2009/066060 WO2010061005A1 (en) 2008-11-28 2009-11-30 Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof
EP09795949A EP2370474B1 (en) 2008-11-28 2009-11-30 Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof

Publications (1)

Publication Number Publication Date
PL2370474T3 true PL2370474T3 (pl) 2013-03-29

Family

ID=41210473

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09795949T PL2370474T3 (pl) 2008-11-28 2009-11-30 Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli

Country Status (15)

Country Link
US (2) US8858999B2 (pl)
EP (1) EP2370474B1 (pl)
JP (1) JP5607061B2 (pl)
CN (1) CN102227448B (pl)
BR (1) BRPI0920965B1 (pl)
CA (1) CA2744892C (pl)
DK (1) DK2370474T3 (pl)
ES (1) ES2397987T3 (pl)
HK (1) HK1162546A1 (pl)
IT (1) ITRM20080636A1 (pl)
MX (1) MX2011005528A (pl)
PL (1) PL2370474T3 (pl)
RU (1) RU2523182C2 (pl)
SI (1) SI2370474T1 (pl)
WO (1) WO2010061005A1 (pl)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
EP3498299A1 (en) 2007-11-16 2019-06-19 Aclaris Therapeutics, Inc. Compositions and methods for treating purpura
US8394782B2 (en) 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
EP2324064B1 (en) 2008-09-02 2017-11-08 Tautona Group LP Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
ITRM20080636A1 (it) 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.
CZ302503B6 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace
CZ2009836A3 (cs) 2009-12-11 2011-06-22 Contipro C A.S. Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
AU2010348090B2 (en) 2010-03-12 2015-09-03 Allergan Industrie Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition
EP4062950A1 (en) 2010-03-22 2022-09-28 Allergan, Inc. Syringe comprising dermal filler for soft tissue augmentation
IT1401498B1 (it) 2010-07-30 2013-07-26 Mero Srl Idrogelo a base di acido ialuronico e suo uso in ortopedia
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
CZ304072B6 (cs) * 2011-04-26 2013-09-25 Contipro Biotech S.R.O. Amfoterní materiál na bázi sítované kyseliny hyaluronové, zpusob jeho prípravy, materiály obsahující aktivní cinidla uzavrené v síti hyaluronanu, zpusob jejich prípravy a jejich pouzití
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
JP6009550B2 (ja) 2011-06-03 2016-10-19 アラーガン、インコーポレイテッドAllergan,Incorporated 抗酸化物質を含む皮膚充填剤組成物
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
JP5714456B2 (ja) * 2011-09-07 2015-05-07 株式会社シード 重合性ヒアルロン酸誘導体、ならびにその重合体を含むヒアルロン酸ヒドロゲルおよびコンタクトレンズ
CZ2012136A3 (cs) 2012-02-28 2013-06-05 Contipro Biotech S.R.O. Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití
KR101240518B1 (ko) * 2012-03-26 2013-03-11 주식회사 제네웰 생체 적합성 고분자를 이용한 이식용 재료
US20150111812A1 (en) 2012-05-31 2015-04-23 Cornell University Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof
CZ304512B6 (cs) 2012-08-08 2014-06-11 Contipro Biotech S.R.O. Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití
CZ2012842A3 (cs) 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
CZ304266B6 (cs) 2012-11-27 2014-02-05 Contipro Biotech S.R.O. Nekonečná vlákna na bázi hyaluronanu selektivně oxidovaného v poloze 6 N-acetyl-D-glukosaminové části, jejich příprava, použití, nitě, střiže, příze, textilie a způsob jejich úpravy
US9623157B2 (en) 2013-03-15 2017-04-18 Lake Region Manufacturing, Inc. Modified hyaluronate hydrophilic compositions, coatings and methods
WO2014152488A2 (en) 2013-03-15 2014-09-25 Dreher Matthew R Imageable embolic microsphere
US20140275340A1 (en) * 2013-03-15 2014-09-18 Lake Region Manufacturing, Inc. d/b/a Lake Region Medical Modified hyaluronate hydrophilic compositions, coatings and methods
CZ305153B6 (cs) 2014-03-11 2015-05-20 Contipro Biotech S.R.O. Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití
CN103910886B (zh) * 2014-03-24 2016-04-06 海南大学 半胱氨酸功能化的透明质酸结合物及其合成方法以及在可注射原位形成的水凝胶中的应用
CN106488772B (zh) * 2014-05-07 2020-11-27 内米西斯有限公司 用于乳糜泄的口服酶疗法的甲基丙烯酸透明质酸衍生物的水凝胶
CZ2014451A3 (cs) 2014-06-30 2016-01-13 Contipro Pharma A.S. Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití
ES2761558T3 (es) 2014-09-30 2020-05-20 Allergan Ind Sas Composiciones de hidrogel estables que incluyen aditivos
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
CZ309295B6 (cs) 2015-03-09 2022-08-10 Contipro A.S. Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití
WO2016176461A1 (en) * 2015-04-29 2016-11-03 Waters Technologies Corporation High purity chromatographic materials comprising ion paired-bonded phases for supercritical fluid chromatography
CZ306479B6 (cs) 2015-06-15 2017-02-08 Contipro A.S. Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin
CZ306662B6 (cs) 2015-06-26 2017-04-26 Contipro A.S. Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití
ES2914684T3 (es) * 2015-08-19 2022-06-15 Univ Iowa Res Found Terapia preventiva para la artrosis postraumática
EP3156044A1 (en) * 2015-10-16 2017-04-19 Merz Pharma GmbH & Co. KGaA In situ cross-linkable polysaccharide compositions and uses thereof
DK3623390T3 (da) 2015-12-29 2023-09-25 Galderma Sa Kulhydrattværbinder
CN105770983B (zh) * 2016-03-14 2019-02-19 武汉纺织大学 一种透明质酸生物粘合剂的制备方法
JP6675247B2 (ja) * 2016-03-28 2020-04-01 株式会社シード フィブロイン−ヒアルロン酸ハイドロゲル複合体
CZ308106B6 (cs) 2016-06-27 2020-01-08 Contipro A.S. Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití
CN106279729A (zh) * 2016-08-26 2017-01-04 北京大清生物技术有限公司 一种透明质酸交联凝胶及其制备方法与应用
FR3060239A1 (fr) * 2016-12-14 2018-06-15 Ge Energy Products France Snc Procede de determination d'un profil de reponse en statisme d'une machine electrique reliee a un reseau electrique
JP2018153296A (ja) * 2017-03-16 2018-10-04 Jsr株式会社 不飽和化合物を含有する組成物
SG10202107829YA (en) 2017-03-22 2021-08-30 Genentech Inc Hydrogel cross-linked hyaluronic acid prodrug compositions and methods
US10263552B2 (en) * 2017-08-08 2019-04-16 Rolls-Royce North American Technologies Inc. Anticipatory control using output shaft speed
CN108187130B (zh) * 2017-09-15 2020-08-18 海宁侏罗纪生物科技有限公司 一种用于生物损伤修复或止血的试剂及其应用
IT201700122135A1 (it) * 2017-10-26 2019-04-26 Jointherapeutics S R L Acido ialuronico funzionalizzato o suo derivato nel trattamento di stati infiammatori
US20210015967A1 (en) * 2018-03-23 2021-01-21 Kaohsiung Medical University Method for preparing hyaluronic acid hydrogel microparticles and use thereof in repairing articular cartilage defects
EP3659632A1 (en) 2018-11-29 2020-06-03 Nestlé Skin Health SA Post-crosslinking partial degradation of amide crosslinked hydrogels
CN110384822B (zh) * 2019-08-19 2021-11-16 江苏人冠医疗科技有限公司 眼用粘合封闭胶及其制备方法
CN110433320A (zh) * 2019-09-12 2019-11-12 深圳刚华健医疗有限公司 一种医用敷料的制备方法
CN112812200B (zh) * 2019-11-18 2023-06-16 孛朗孚(杭州)生物科技有限公司 巯基改性高分子化合物及其制备方法和用途
TW202128127A (zh) 2019-12-02 2021-08-01 瑞士商葛德瑪控股公司 高分子量美容組合物
US11904006B2 (en) 2019-12-11 2024-02-20 University Of Iowa Research Foundation Poly(diaminosulfide) particle-based vaccine
WO2021246764A1 (ko) * 2020-06-01 2021-12-09 주식회사 엘지화학 고분자 마이크로 입자의 제조방법, 고분자 마이크로 입자, 이를 포함하는 의료용 조성물, 미용 조성물, 의료 용품 및 미용 용품
IT202000028445A1 (it) 2020-11-25 2022-05-25 Univ Degli Studi Di Palermo Nanosistema per la diagnosi ed il trattamento fototermico di tumori
WO2023148619A1 (en) 2022-02-01 2023-08-10 Galderma Holding SA Methods of producing crosslinked hyaluronic acid hydrogels
CN115636884B (zh) * 2022-12-23 2023-03-28 北京格林意锐医药科技有限责任公司 一种透明质酸钠衍生物制备方法及交联透明质酸钠和用途

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06279502A (ja) * 1993-03-29 1994-10-04 Asahi Chem Ind Co Ltd カーボネート化セルロース誘導体の製法
JPH06279501A (ja) * 1993-03-29 1994-10-04 Asahi Chem Ind Co Ltd カーボネート化セルロース誘導体及びその製造方法
IT1268955B1 (it) * 1994-03-11 1997-03-18 Fidia Advanced Biopolymers Srl Esteri attivi di polisaccaridi carbossilici
WO1997018244A1 (en) * 1995-11-15 1997-05-22 Seikagaku Corporation Photocured cross-linked-hyaluronic acid gel and method of preparation thereof
RU2191782C2 (ru) * 2000-09-21 2002-10-27 Институт нефтехимии и катализа АН РБ и УНЦ РАН Способ получения модифицированной гиалуроновой кислоты
JP2004292465A (ja) * 2000-11-30 2004-10-21 Denki Kagaku Kogyo Kk ヒドロキサム酸誘導体とヒアルロン酸の結合体
ITTS20010013A1 (it) * 2001-06-04 2002-12-04 Ct Ricerche Poly Tec H A R L S Nuovi derivati di ialuronano.
WO2003002125A2 (en) * 2001-06-29 2003-01-09 Astion A/S Combination of aminosugars and cysteine or cysteine derivatives
JP4755496B2 (ja) * 2003-09-08 2011-08-24 中外製薬株式会社 ヒアルロン酸修飾物、及びそれを用いた薬物担体
GB2408741B (en) * 2003-12-04 2008-06-18 Ind Tech Res Inst Hyaluronic acid derivative with urethane linkage
JP5001645B2 (ja) * 2004-04-02 2012-08-15 電気化学工業株式会社 ヒアルロン酸−メトトレキサート結合体
JP5060131B2 (ja) * 2004-09-07 2012-10-31 中外製薬株式会社 水溶性ヒアルロン酸修飾物の製造方法
US7879818B2 (en) * 2005-12-23 2011-02-01 Janos Borbely Hyaluronic acid-based cross-linked nanoparticles
KR100849185B1 (ko) * 2006-01-19 2008-07-30 서울산업대학교 산학협력단 키토산 또는 히알루론산-폴리에틸렌옥사이드 및키토산-히알루론산-폴리에틸렌옥사이드를 기저로 하는하이드로젤과  이의 제조방법
ITRM20080636A1 (it) 2008-11-28 2010-05-29 Univ Palermo Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli.

Also Published As

Publication number Publication date
EP2370474B1 (en) 2012-10-24
JP5607061B2 (ja) 2014-10-15
RU2523182C2 (ru) 2014-07-20
HK1162546A1 (en) 2012-08-31
EP2370474A1 (en) 2011-10-05
CN102227448B (zh) 2014-04-02
SI2370474T1 (sl) 2013-02-28
DK2370474T3 (da) 2013-01-14
WO2010061005A1 (en) 2010-06-03
US8858999B2 (en) 2014-10-14
ES2397987T3 (es) 2013-03-12
US20150183891A1 (en) 2015-07-02
MX2011005528A (es) 2011-08-17
BRPI0920965B1 (pt) 2019-07-09
US9410000B2 (en) 2016-08-09
JP2012510535A (ja) 2012-05-10
CN102227448A (zh) 2011-10-26
ITRM20080636A1 (it) 2010-05-29
BRPI0920965A2 (pt) 2016-09-06
CA2744892C (en) 2016-10-25
US20110236486A1 (en) 2011-09-29
RU2011126353A (ru) 2013-01-10
CA2744892A1 (en) 2010-06-03

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