PL2370474T3 - Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli - Google Patents
Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeliInfo
- Publication number
- PL2370474T3 PL2370474T3 PL09795949T PL09795949T PL2370474T3 PL 2370474 T3 PL2370474 T3 PL 2370474T3 PL 09795949 T PL09795949 T PL 09795949T PL 09795949 T PL09795949 T PL 09795949T PL 2370474 T3 PL2370474 T3 PL 2370474T3
- Authority
- PL
- Poland
- Prior art keywords
- hydrogels
- formation
- hyaluronic acid
- acid functionalized
- functionalized derivatives
- Prior art date
Links
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 229920002674 hyaluronan Polymers 0.000 title 1
- 229960003160 hyaluronic acid Drugs 0.000 title 1
- 239000000017 hydrogel Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
- B23K—SOLDERING OR UNSOLDERING; WELDING; CLADDING OR PLATING BY SOLDERING OR WELDING; CUTTING BY APPLYING HEAT LOCALLY, e.g. FLAME CUTTING; WORKING BY LASER BEAM
- B23K9/00—Arc welding or cutting
- B23K9/10—Other electric circuits therefor; Protective circuits; Remote controls
Landscapes
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Plasma & Fusion (AREA)
- Molecular Biology (AREA)
- Mechanical Engineering (AREA)
- Physics & Mathematics (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Arc Welding Control (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000636A ITRM20080636A1 (it) | 2008-11-28 | 2008-11-28 | Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli. |
| EP09795949A EP2370474B1 (en) | 2008-11-28 | 2009-11-30 | Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof |
| PCT/EP2009/066060 WO2010061005A1 (en) | 2008-11-28 | 2009-11-30 | Method to produce hyaluronic acid functionalized derivatives and formation of hydrogels thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2370474T3 true PL2370474T3 (pl) | 2013-03-29 |
Family
ID=41210473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09795949T PL2370474T3 (pl) | 2008-11-28 | 2009-11-30 | Sposób wytwarzania funkcjonalizowanych pochodnych kwasu hialuronowego i wytwarzanie z nich hydrożeli |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8858999B2 (pl) |
| EP (1) | EP2370474B1 (pl) |
| JP (1) | JP5607061B2 (pl) |
| CN (1) | CN102227448B (pl) |
| BR (1) | BRPI0920965B1 (pl) |
| CA (1) | CA2744892C (pl) |
| DK (1) | DK2370474T3 (pl) |
| ES (1) | ES2397987T3 (pl) |
| IT (1) | ITRM20080636A1 (pl) |
| MX (1) | MX2011005528A (pl) |
| PL (1) | PL2370474T3 (pl) |
| RU (1) | RU2523182C2 (pl) |
| SI (1) | SI2370474T1 (pl) |
| WO (1) | WO2010061005A1 (pl) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| BRPI0819075A2 (pt) | 2007-11-16 | 2014-10-07 | Vicept Therapeutics Inc | Método para tratar púrpura em um indivíduo e método para diminuir a púrpura em um indivíduo antes de um procedimento cirúrgico |
| US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| US9228027B2 (en) | 2008-09-02 | 2016-01-05 | Allergan Holdings France S.A.S. | Threads of Hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
| ITRM20080636A1 (it) | 2008-11-28 | 2010-05-29 | Univ Palermo | Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli. |
| CZ302503B6 (cs) | 2009-12-11 | 2011-06-22 | Contipro C A.S. | Zpusob prípravy derivátu kyseliny hyaluronové oxidovaného v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd a zpusob jeho modifikace |
| CZ302504B6 (cs) | 2009-12-11 | 2011-06-22 | Contipro C A.S. | Derivát kyseliny hyaluronové oxidovaný v poloze 6 glukosaminové cásti polysacharidu selektivne na aldehyd, zpusob jeho prípravy a zpusob jeho modifikace |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| KR101764451B1 (ko) | 2010-03-12 | 2017-08-02 | 알러간 인더스트리 에스에이에스 | 피부 상태 개선을 위한 히알루론안 폴리머 및 만니톨을 포함하는 유체 조성물 |
| CA2794254C (en) | 2010-03-22 | 2018-09-04 | Allergan, Inc. | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
| IT1401498B1 (it) | 2010-07-30 | 2013-07-26 | Mero Srl | Idrogelo a base di acido ialuronico e suo uso in ortopedia |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| CZ304072B6 (cs) * | 2011-04-26 | 2013-09-25 | Contipro Biotech S.R.O. | Amfoterní materiál na bázi sítované kyseliny hyaluronové, zpusob jeho prípravy, materiály obsahující aktivní cinidla uzavrené v síti hyaluronanu, zpusob jejich prípravy a jejich pouzití |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| AU2012262047A1 (en) | 2011-06-03 | 2014-01-16 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
| US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
| JP5714456B2 (ja) * | 2011-09-07 | 2015-05-07 | 株式会社シード | 重合性ヒアルロン酸誘導体、ならびにその重合体を含むヒアルロン酸ヒドロゲルおよびコンタクトレンズ |
| CZ2012136A3 (cs) | 2012-02-28 | 2013-06-05 | Contipro Biotech S.R.O. | Deriváty na bázi kyseliny hyaluronové schopné tvorit hydrogely, zpusob jejich prípravy, hydrogely na bázi techto derivátu, zpusob jejich prípravy a pouzití |
| KR101240518B1 (ko) * | 2012-03-26 | 2013-03-11 | 주식회사 제네웰 | 생체 적합성 고분자를 이용한 이식용 재료 |
| WO2013181566A1 (en) | 2012-05-31 | 2013-12-05 | Cornell University | Polysaccharide-based hydrogels and hybrid hydrogels and precursors thereof, methods of making same, and uses thereof |
| CZ304512B6 (cs) | 2012-08-08 | 2014-06-11 | Contipro Biotech S.R.O. | Derivát kyseliny hyaluronové, způsob jeho přípravy, způsob jeho modifikace a použití |
| CZ304654B6 (cs) | 2012-11-27 | 2014-08-20 | Contipro Biotech S.R.O. | Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití |
| CZ2012843A3 (cs) | 2012-11-27 | 2014-02-05 | Contipro Biotech S.R.O. | Nekonečná vlákna na bázi hyaluronanu, selektivně oxidovaného v poloze 6 N-acetyl-D-glukosaminové části, jejich příprava, použití, nitě, střiže, příze, textilie a způsob jejich úpravy |
| US9623157B2 (en) | 2013-03-15 | 2017-04-18 | Lake Region Manufacturing, Inc. | Modified hyaluronate hydrophilic compositions, coatings and methods |
| WO2014152488A2 (en) * | 2013-03-15 | 2014-09-25 | Dreher Matthew R | Imageable embolic microsphere |
| US20140275340A1 (en) * | 2013-03-15 | 2014-09-18 | Lake Region Manufacturing, Inc. d/b/a Lake Region Medical | Modified hyaluronate hydrophilic compositions, coatings and methods |
| CZ305153B6 (cs) | 2014-03-11 | 2015-05-20 | Contipro Biotech S.R.O. | Konjugáty oligomeru kyseliny hyaluronové nebo její soli, způsob jejich přípravy a použití |
| CN103910886B (zh) * | 2014-03-24 | 2016-04-06 | 海南大学 | 半胱氨酸功能化的透明质酸结合物及其合成方法以及在可注射原位形成的水凝胶中的应用 |
| RU2679638C2 (ru) * | 2014-05-07 | 2019-02-12 | Немисис Лимитед | Гидрогели метакриловых производных гиалуроновой кислоты для пероральной ферментной терапии глютеновой энтеропатии |
| CZ2014451A3 (cs) | 2014-06-30 | 2016-01-13 | Contipro Pharma A.S. | Protinádorová kompozice na bázi kyseliny hyaluronové a anorganických nanočástic, způsob její přípravy a použití |
| EP3620184A1 (en) | 2014-09-30 | 2020-03-11 | Allergan Industrie, SAS | Stable hydrogel compositions including additives |
| WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| KR102759640B1 (ko) | 2015-02-13 | 2025-01-23 | 알러간 인더스트리 에스에이에스 | 턱과 같은 얼굴 이목구비를 조각, 확대 또는 교정하기 위한 임플란트 |
| CZ309295B6 (cs) | 2015-03-09 | 2022-08-10 | Contipro A.S. | Samonosný, biodegradabilní film na bázi hydrofobizované kyseliny hyaluronové, způsob jeho přípravy a použití |
| CN108136275A (zh) * | 2015-04-29 | 2018-06-08 | 沃特世科技公司 | 用于超临界流体色谱法的包含离子配对键合相的高纯度色谱材料 |
| CZ2015398A3 (cs) | 2015-06-15 | 2017-02-08 | Contipro A.S. | Způsob síťování polysacharidů s využitím fotolabilních chránicích skupin |
| CZ306662B6 (cs) | 2015-06-26 | 2017-04-26 | Contipro A.S. | Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití |
| CN114010640A (zh) | 2015-08-19 | 2022-02-08 | 爱荷华大学研究基金会 | 创伤后骨关节炎的预防性治疗 |
| EP3156044A1 (en) * | 2015-10-16 | 2017-04-19 | Merz Pharma GmbH & Co. KGaA | In situ cross-linkable polysaccharide compositions and uses thereof |
| RU2018126365A (ru) | 2015-12-29 | 2020-01-30 | Гальдерма С.А. | Способ расщепления амидных связей |
| CN105770983B (zh) * | 2016-03-14 | 2019-02-19 | 武汉纺织大学 | 一种透明质酸生物粘合剂的制备方法 |
| JP6675247B2 (ja) * | 2016-03-28 | 2020-04-01 | 株式会社シード | フィブロイン−ヒアルロン酸ハイドロゲル複合体 |
| CZ308106B6 (cs) | 2016-06-27 | 2020-01-08 | Contipro A.S. | Nenasycené deriváty polysacharidů, způsob jejich přípravy a jejich použití |
| CN106279729A (zh) * | 2016-08-26 | 2017-01-04 | 北京大清生物技术有限公司 | 一种透明质酸交联凝胶及其制备方法与应用 |
| FR3060239A1 (fr) * | 2016-12-14 | 2018-06-15 | Ge Energy Products France Snc | Procede de determination d'un profil de reponse en statisme d'une machine electrique reliee a un reseau electrique |
| JP2018153296A (ja) * | 2017-03-16 | 2018-10-04 | Jsr株式会社 | 不飽和化合物を含有する組成物 |
| AU2018240375C1 (en) | 2017-03-22 | 2024-02-01 | Ascendis Pharma A/S | Hydrogel cross-linked hyaluronic acid prodrug compositions and methods |
| US10263552B2 (en) * | 2017-08-08 | 2019-04-16 | Rolls-Royce North American Technologies Inc. | Anticipatory control using output shaft speed |
| CN108187130B (zh) * | 2017-09-15 | 2020-08-18 | 海宁侏罗纪生物科技有限公司 | 一种用于生物损伤修复或止血的试剂及其应用 |
| IT201700122135A1 (it) * | 2017-10-26 | 2019-04-26 | Jointherapeutics S R L | Acido ialuronico funzionalizzato o suo derivato nel trattamento di stati infiammatori |
| WO2019178825A1 (zh) * | 2018-03-23 | 2019-09-26 | 高雄医学大学 | 玻尿酸水胶微粒的制备方法及其修复关节软骨缺损的用途 |
| EP3659632A1 (en) | 2018-11-29 | 2020-06-03 | Nestlé Skin Health SA | Post-crosslinking partial degradation of amide crosslinked hydrogels |
| CN110384822B (zh) * | 2019-08-19 | 2021-11-16 | 江苏人冠医疗科技有限公司 | 眼用粘合封闭胶及其制备方法 |
| CN110433320A (zh) * | 2019-09-12 | 2019-11-12 | 深圳刚华健医疗有限公司 | 一种医用敷料的制备方法 |
| CN112812200B (zh) * | 2019-11-18 | 2023-06-16 | 孛朗孚(杭州)生物科技有限公司 | 巯基改性高分子化合物及其制备方法和用途 |
| JP7730323B2 (ja) | 2019-12-02 | 2025-08-27 | ガルデルマ ホールディング エスエー | 高分子量美容組成物 |
| US11904006B2 (en) | 2019-12-11 | 2024-02-20 | University Of Iowa Research Foundation | Poly(diaminosulfide) particle-based vaccine |
| US12296054B2 (en) | 2020-06-01 | 2025-05-13 | Lg Chem, Ltd. | Method of preparing polymeric microparticles, polymeric microparticles, medical composition, cosmetic composition, medical articles and cosmetic articles using the same |
| IT202000028445A1 (it) | 2020-11-25 | 2022-05-25 | Univ Degli Studi Di Palermo | Nanosistema per la diagnosi ed il trattamento fototermico di tumori |
| TR202022151A2 (tr) * | 2020-12-29 | 2022-07-21 | Vsy Biyoteknoloji Ve Ilac Sanayi Anonim Sirketi | Enjekte edi̇lebi̇li̇r fotoçapraz bağli hi̇yaluroni̇k asi̇t hi̇drojeller, bunlarin üreti̇m yöntemi̇ ve osteoartri̇t tedavi̇si̇ i̇çi̇n kullanimi |
| EP4473021A1 (en) | 2022-02-01 | 2024-12-11 | Galderma Holding SA | Methods of producing crosslinked hyaluronic acid hydrogels |
| CN115636884B (zh) * | 2022-12-23 | 2023-03-28 | 北京格林意锐医药科技有限责任公司 | 一种透明质酸钠衍生物制备方法及交联透明质酸钠和用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06279502A (ja) * | 1993-03-29 | 1994-10-04 | Asahi Chem Ind Co Ltd | カーボネート化セルロース誘導体の製法 |
| JPH06279501A (ja) * | 1993-03-29 | 1994-10-04 | Asahi Chem Ind Co Ltd | カーボネート化セルロース誘導体及びその製造方法 |
| IT1268955B1 (it) * | 1994-03-11 | 1997-03-18 | Fidia Advanced Biopolymers Srl | Esteri attivi di polisaccaridi carbossilici |
| CN1098863C (zh) * | 1995-11-15 | 2003-01-15 | 生化学株式会社 | 光固化交联透明质酸凝胶、其制备方法和生物医学材料 |
| RU2191782C2 (ru) * | 2000-09-21 | 2002-10-27 | Институт нефтехимии и катализа АН РБ и УНЦ РАН | Способ получения модифицированной гиалуроновой кислоты |
| JP2004292465A (ja) * | 2000-11-30 | 2004-10-21 | Denki Kagaku Kogyo Kk | ヒドロキサム酸誘導体とヒアルロン酸の結合体 |
| ITTS20010013A1 (it) * | 2001-06-04 | 2002-12-04 | Ct Ricerche Poly Tec H A R L S | Nuovi derivati di ialuronano. |
| WO2003002125A2 (en) * | 2001-06-29 | 2003-01-09 | Astion A/S | Combination of aminosugars and cysteine or cysteine derivatives |
| KR101121403B1 (ko) * | 2003-09-08 | 2012-04-12 | 추가이 세이야쿠 가부시키가이샤 | 히알루론산 수식물, 및 그것을 사용한 약물 담체 |
| GB2408741B (en) * | 2003-12-04 | 2008-06-18 | Ind Tech Res Inst | Hyaluronic acid derivative with urethane linkage |
| US7807675B2 (en) * | 2004-04-02 | 2010-10-05 | Denki Kagaku Kogyo Kabushiki Kaisha | Hyaluronic acid-methotrexate conjugate |
| TW200612991A (en) * | 2004-09-07 | 2006-05-01 | Chugai Pharmaceutical Co Ltd | Process for producing water-soluble hyaluronic acid modification |
| US7879818B2 (en) * | 2005-12-23 | 2011-02-01 | Janos Borbely | Hyaluronic acid-based cross-linked nanoparticles |
| KR100849185B1 (ko) * | 2006-01-19 | 2008-07-30 | 서울산업대학교 산학협력단 | 키토산 또는 히알루론산-폴리에틸렌옥사이드 및키토산-히알루론산-폴리에틸렌옥사이드를 기저로 하는하이드로젤과 이의 제조방법 |
| ITRM20080636A1 (it) | 2008-11-28 | 2010-05-29 | Univ Palermo | Procedimento per la produzione di derivati funzionalizzati dell acido ialuronico e relativi idrogeli. |
-
2008
- 2008-11-28 IT IT000636A patent/ITRM20080636A1/it unknown
-
2009
- 2009-01-30 US US13/131,098 patent/US8858999B2/en active Active
- 2009-11-30 CN CN200980147761.7A patent/CN102227448B/zh active Active
- 2009-11-30 JP JP2011537999A patent/JP5607061B2/ja active Active
- 2009-11-30 BR BRPI0920965-4A patent/BRPI0920965B1/pt not_active IP Right Cessation
- 2009-11-30 MX MX2011005528A patent/MX2011005528A/es active IP Right Grant
- 2009-11-30 EP EP09795949A patent/EP2370474B1/en active Active
- 2009-11-30 PL PL09795949T patent/PL2370474T3/pl unknown
- 2009-11-30 WO PCT/EP2009/066060 patent/WO2010061005A1/en not_active Ceased
- 2009-11-30 ES ES09795949T patent/ES2397987T3/es active Active
- 2009-11-30 RU RU2011126353/13A patent/RU2523182C2/ru not_active IP Right Cessation
- 2009-11-30 DK DK09795949.8T patent/DK2370474T3/da active
- 2009-11-30 SI SI200930470T patent/SI2370474T1/sl unknown
- 2009-11-30 CA CA2744892A patent/CA2744892C/en active Active
-
2014
- 2014-11-13 US US14/507,474 patent/US9410000B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM20080636A1 (it) | 2010-05-29 |
| CA2744892C (en) | 2016-10-25 |
| EP2370474B1 (en) | 2012-10-24 |
| ES2397987T3 (es) | 2013-03-12 |
| CN102227448B (zh) | 2014-04-02 |
| BRPI0920965A2 (pt) | 2016-09-06 |
| JP2012510535A (ja) | 2012-05-10 |
| HK1162546A1 (en) | 2012-08-31 |
| EP2370474A1 (en) | 2011-10-05 |
| WO2010061005A1 (en) | 2010-06-03 |
| JP5607061B2 (ja) | 2014-10-15 |
| RU2523182C2 (ru) | 2014-07-20 |
| DK2370474T3 (da) | 2013-01-14 |
| US9410000B2 (en) | 2016-08-09 |
| MX2011005528A (es) | 2011-08-17 |
| US20150183891A1 (en) | 2015-07-02 |
| RU2011126353A (ru) | 2013-01-10 |
| US8858999B2 (en) | 2014-10-14 |
| CA2744892A1 (en) | 2010-06-03 |
| US20110236486A1 (en) | 2011-09-29 |
| BRPI0920965B1 (pt) | 2019-07-09 |
| CN102227448A (zh) | 2011-10-26 |
| SI2370474T1 (sl) | 2013-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2370474T1 (sl) | Postopek izdelave funkcionaliziranih derivatov hiarulonske kisline in tvorba hidrogelov le-teh | |
| IL223420A0 (en) | Large-scale production of soluble hyaluronidase | |
| IL208977A (en) | A method for making butyric acid | |
| AP3117A (en) | Method of production of ethanol from two differentstarting materials | |
| EP2635634A4 (en) | METHOD OF USING ALDEHYDE FUNCTIONALITY POLYMERS FOR INCREASING THE PERFORMANCE OF A PAPER MACHINE AND IMPROVING COLLAGE | |
| ZA201200727B (en) | Modified hyaluronic acid polymer compositions and related methods | |
| IL219865A (en) | Forms of acid salts of polymer-drug couplings, preparations containing them, methods for their preparation and uses | |
| EP2319800A4 (en) | PROCESS FOR THE PREPARATION OF HEXAFLUORO PHOSPHATES | |
| SI2415743T1 (sl) | Piceatanol vsebujoč sestavek in postopek proizvodnje piceatanol vsebujočega sestavka | |
| BR112012013954A2 (pt) | derivado de ácido hialurônico, método de preparação do derivado de ácido hialurônico e método de modificação do derivado de ácido hialurônico | |
| IL215376A0 (en) | Methods and microorganisms for production of c4-dicarboxylic acids | |
| EP2264144A4 (en) | PROCESS FOR THE PREPARATION OF 5'-GUANYLIC ACID | |
| ZA201006971B (en) | Methods and compositions for production of acetaldehyde | |
| ZA201005788B (en) | Process for production of thiophene compound and intermediate thereof | |
| EP2265625A4 (en) | PROCESS FOR CONTINUOUS ACIDIC HYDROLYSIS OF CELLULOSE CONTAINING SUBSTANCES | |
| GB0809169D0 (en) | Method of L-lysine production | |
| PT2161022E (pt) | Produção de ligantes de fosfato e ligantes de fosfato produzidos de acordo com o método | |
| PL385356A1 (pl) | Sposób wytwarzania tadalafilu | |
| EP2251329A4 (en) | PROCESS FOR THE PRODUCTION OF 3-AMINO-2-CHLORO-6-TRIFLUOROMETHYLPYRIDINE | |
| EP2448916A4 (en) | PRODUCTION OF TRANS-4-AMINOCYCLOPENT-2-ENE-1-CARBOXYLIC ACID DERIVATIVES | |
| PL388213A1 (pl) | Nowe pochodne politienylenowinylenu z ugrupowaniami alkilowymi oraz sposób ich wytwarzania | |
| AU2008902353A0 (en) | Production of hyaluronic acid | |
| GB0801977D0 (en) | Production of l-iduronate containing polysaccharides | |
| PL384822A1 (pl) | Sposób wytwarzania wyrobu piekarskiego | |
| GB0802615D0 (en) | Method of production |