PL1613347T3 - Humanizowane przeciwciała rozpoznające peptyd beta amyloidowy - Google Patents

Humanizowane przeciwciała rozpoznające peptyd beta amyloidowy

Info

Publication number
PL1613347T3
PL1613347T3 PL04720353T PL04720353T PL1613347T3 PL 1613347 T3 PL1613347 T3 PL 1613347T3 PL 04720353 T PL04720353 T PL 04720353T PL 04720353 T PL04720353 T PL 04720353T PL 1613347 T3 PL1613347 T3 PL 1613347T3
Authority
PL
Poland
Prior art keywords
humanized antibodies
amyloid peptide
beta amyloid
recognize beta
recognize
Prior art date
Application number
PL04720353T
Other languages
English (en)
Inventor
Guriq Basi
Jose W Saldanha
Original Assignee
Janssen Alzheimer Immunotherap
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32987350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1613347(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Alzheimer Immunotherap, Wyeth Llc filed Critical Janssen Alzheimer Immunotherap
Publication of PL1613347T3 publication Critical patent/PL1613347T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cold Air Circulating Systems And Constructional Details In Refrigerators (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL04720353T 2003-03-12 2004-03-12 Humanizowane przeciwciała rozpoznające peptyd beta amyloidowy PL1613347T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,389 US7179892B2 (en) 2000-12-06 2003-03-12 Humanized antibodies that recognize beta amyloid peptide
PCT/US2004/007503 WO2004080419A2 (en) 2003-03-12 2004-03-12 Humanized antibodies that recognize beta amyloid peptide
EP04720353A EP1613347B1 (en) 2003-03-12 2004-03-12 Humanized antibodies that recognize beta amyloid peptide

Publications (1)

Publication Number Publication Date
PL1613347T3 true PL1613347T3 (pl) 2011-06-30

Family

ID=32987350

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04720353T PL1613347T3 (pl) 2003-03-12 2004-03-12 Humanizowane przeciwciała rozpoznające peptyd beta amyloidowy

Country Status (13)

Country Link
US (2) US7179892B2 (pl)
EP (2) EP2221064A1 (pl)
JP (1) JP2007525160A (pl)
AT (1) ATE479442T1 (pl)
CA (1) CA2518275C (pl)
CY (1) CY1110963T1 (pl)
DE (1) DE602004028920D1 (pl)
DK (1) DK1613347T3 (pl)
ES (1) ES2349374T3 (pl)
PL (1) PL1613347T3 (pl)
PT (1) PT1613347E (pl)
SI (1) SI1613347T1 (pl)
WO (1) WO2004080419A2 (pl)

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EP1613347B1 (en) 2010-09-01
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EP1613347A4 (en) 2007-06-06
ATE479442T1 (de) 2010-09-15
US20040087777A1 (en) 2004-05-06
US7179892B2 (en) 2007-02-20
PT1613347E (pt) 2010-11-24
CA2518275C (en) 2017-02-14
US20060280743A1 (en) 2006-12-14
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DK1613347T3 (da) 2010-11-29
DE602004028920D1 (de) 2010-10-14
CA2518275A1 (en) 2004-09-23
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WO2004080419A3 (en) 2005-05-06
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