MX2009003542A - Metodos y composiciones con opalescencia reducida. - Google Patents
Metodos y composiciones con opalescencia reducida.Info
- Publication number
- MX2009003542A MX2009003542A MX2009003542A MX2009003542A MX2009003542A MX 2009003542 A MX2009003542 A MX 2009003542A MX 2009003542 A MX2009003542 A MX 2009003542A MX 2009003542 A MX2009003542 A MX 2009003542A MX 2009003542 A MX2009003542 A MX 2009003542A
- Authority
- MX
- Mexico
- Prior art keywords
- ionic strength
- aggregates
- antibody
- modification
- solutions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Inorganic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Se describen métodos para reducir la apariencia opalescente de una preparación proteínica que modifica la fuerza iónica de la preparación, así como composiciones, por ejemplo, composiciones farmacéuticas, de una proteína concentrada con una opalescencia disminuida. También se describen métodos de purificación que monitorizan y/o reducen las concentraciones de sal durante las etapas seleccionadas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US85165106P | 2006-10-12 | 2006-10-12 | |
PCT/US2007/021904 WO2008045563A2 (en) | 2006-10-12 | 2007-10-12 | Modification of ionic strength in antibody-solutions to reduce opalescence/aggregates |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009003542A true MX2009003542A (es) | 2009-04-15 |
Family
ID=39205011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009003542A MX2009003542A (es) | 2006-10-12 | 2007-10-12 | Metodos y composiciones con opalescencia reducida. |
Country Status (12)
Country | Link |
---|---|
US (1) | US7744890B2 (es) |
EP (1) | EP2076287A2 (es) |
JP (1) | JP2010506839A (es) |
KR (1) | KR20090069330A (es) |
CN (1) | CN101522219A (es) |
AU (1) | AU2007308145A1 (es) |
BR (1) | BRPI0719250A2 (es) |
CA (1) | CA2665423A1 (es) |
IL (1) | IL197778A0 (es) |
MX (1) | MX2009003542A (es) |
RU (1) | RU2009111138A (es) |
WO (1) | WO2008045563A2 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010506839A (ja) | 2006-10-12 | 2010-03-04 | ワイス エルエルシー | 乳光の低減を伴う方法および組成物 |
EP2020240A1 (en) * | 2007-07-30 | 2009-02-04 | Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe | Methods and substances for the treatment of Alzheimer's |
EP2297203A1 (en) | 2008-06-30 | 2011-03-23 | Novo Nordisk A/S | Anti-human interleukin-20 antibodies |
CA2751000A1 (en) * | 2009-03-11 | 2010-12-23 | Wyeth Llc | Methods of purifying small modular immunopharmaceutical proteins |
US8454956B2 (en) | 2009-08-31 | 2013-06-04 | National Cheng Kung University | Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies |
EP2518084B1 (en) * | 2009-12-25 | 2016-11-30 | Sekisui Medical Co., Ltd. | Method for measuring human insulin and measurement reagent |
EP3708190A1 (en) * | 2010-02-26 | 2020-09-16 | Novo Nordisk A/S | Stable antibody containing compositions |
CA3101298A1 (en) | 2010-03-01 | 2011-09-09 | Bayer Healthcare Llc | Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi) |
US20130136733A1 (en) | 2010-05-28 | 2013-05-30 | Novo Nordisk A/S | Stable Multi-Dose Compositions Comprising an Antibody and a Preservative |
WO2014015133A1 (en) | 2012-07-19 | 2014-01-23 | National Cheng Kung University | Treatment of osteoarthritis using il-20 antagonists |
US8852588B2 (en) | 2012-08-07 | 2014-10-07 | National Cheng Kung University | Treating allergic airway disorders using anti-IL-20 receptor antibodies |
US8603470B1 (en) | 2012-08-07 | 2013-12-10 | National Cheng Kung University | Use of IL-20 antagonists for treating liver diseases |
US9592297B2 (en) | 2012-08-31 | 2017-03-14 | Bayer Healthcare Llc | Antibody and protein formulations |
WO2017198114A1 (zh) * | 2016-05-19 | 2017-11-23 | 长弘生物科技股份有限公司 | 用于延缓肺纤维化的发病及/或治疗肺纤维化的药剂 |
PL3500856T3 (pl) * | 2016-08-18 | 2021-04-19 | Regeneron Pharmaceuticals, Inc. | Oznaczenie umożliwiające określenie potencjału białka do samoasocjacji za pomocą spektroskopii zależnych od stężenia samoodziaływań nanocząstek (CD-SINS) |
CN107236038B (zh) * | 2017-06-20 | 2020-11-27 | 华兰生物工程股份有限公司 | 微晶纤维素提高蛋白质澄清度的方法及其产品和应用 |
JP7233980B2 (ja) * | 2019-03-08 | 2023-03-07 | キオクシア株式会社 | 粒子計測方法及び検出液 |
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JP2010506839A (ja) | 2006-10-12 | 2010-03-04 | ワイス エルエルシー | 乳光の低減を伴う方法および組成物 |
-
2007
- 2007-10-12 JP JP2009532451A patent/JP2010506839A/ja active Pending
- 2007-10-12 RU RU2009111138/15A patent/RU2009111138A/ru not_active Application Discontinuation
- 2007-10-12 CN CNA2007800368948A patent/CN101522219A/zh active Pending
- 2007-10-12 BR BRPI0719250-9A patent/BRPI0719250A2/pt not_active IP Right Cessation
- 2007-10-12 EP EP07852729A patent/EP2076287A2/en not_active Withdrawn
- 2007-10-12 MX MX2009003542A patent/MX2009003542A/es not_active Application Discontinuation
- 2007-10-12 CA CA002665423A patent/CA2665423A1/en not_active Abandoned
- 2007-10-12 WO PCT/US2007/021904 patent/WO2008045563A2/en active Application Filing
- 2007-10-12 US US11/974,312 patent/US7744890B2/en not_active Expired - Fee Related
- 2007-10-12 KR KR1020097009757A patent/KR20090069330A/ko not_active Application Discontinuation
- 2007-10-12 AU AU2007308145A patent/AU2007308145A1/en not_active Abandoned
-
2009
- 2009-03-24 IL IL197778A patent/IL197778A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20090069330A (ko) | 2009-06-30 |
BRPI0719250A2 (pt) | 2015-06-16 |
US20080154023A1 (en) | 2008-06-26 |
CN101522219A (zh) | 2009-09-02 |
CA2665423A1 (en) | 2008-04-17 |
AU2007308145A1 (en) | 2008-04-17 |
US7744890B2 (en) | 2010-06-29 |
EP2076287A2 (en) | 2009-07-08 |
JP2010506839A (ja) | 2010-03-04 |
WO2008045563A3 (en) | 2008-06-19 |
IL197778A0 (en) | 2011-08-01 |
RU2009111138A (ru) | 2010-11-20 |
WO2008045563A2 (en) | 2008-04-17 |
WO2008045563A9 (en) | 2008-08-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HH | Correction or change in general | ||
FA | Abandonment or withdrawal |