MX2007008790A - Pirazolo piridinas sustituidas, composiciones que las contienen, metodo de produccion de las mismas, y su uso. - Google Patents
Pirazolo piridinas sustituidas, composiciones que las contienen, metodo de produccion de las mismas, y su uso.Info
- Publication number
- MX2007008790A MX2007008790A MX2007008790A MX2007008790A MX2007008790A MX 2007008790 A MX2007008790 A MX 2007008790A MX 2007008790 A MX2007008790 A MX 2007008790A MX 2007008790 A MX2007008790 A MX 2007008790A MX 2007008790 A MX2007008790 A MX 2007008790A
- Authority
- MX
- Mexico
- Prior art keywords
- pyridines
- compositions containing
- production
- substituted pyrazolo
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
Abstract
La invencion se refiere a pirazolo piridinas sustituidas, composiciones que las contienen, un metodo para la produccion de las mismas, y a su uso. La invencion particularmente se refiere a la preparacion de pirazolo piridinas sustituidas, composiciones que las contienen, un metodo para la preparacion de las mismas, y su uso como un medicamento, en particular, como agentes anticancerigenos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0500555A FR2880891B1 (fr) | 2005-01-19 | 2005-01-19 | Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation |
FR0507505A FR2888579A1 (fr) | 2005-07-13 | 2005-07-13 | Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation |
PCT/FR2006/000114 WO2006077319A1 (fr) | 2005-01-19 | 2006-01-18 | Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007008790A true MX2007008790A (es) | 2007-09-11 |
Family
ID=36593766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007008790A MX2007008790A (es) | 2005-01-19 | 2006-01-18 | Pirazolo piridinas sustituidas, composiciones que las contienen, metodo de produccion de las mismas, y su uso. |
Country Status (24)
Country | Link |
---|---|
US (2) | US8008322B2 (es) |
EP (1) | EP1845978B1 (es) |
JP (1) | JP2008527025A (es) |
KR (1) | KR20070098923A (es) |
AR (1) | AR052357A1 (es) |
AT (1) | ATE477799T1 (es) |
AU (1) | AU2006207442A1 (es) |
BR (1) | BRPI0606504A2 (es) |
CA (1) | CA2595041A1 (es) |
CY (1) | CY1110926T1 (es) |
DE (1) | DE602006016233D1 (es) |
DK (1) | DK1845978T3 (es) |
HR (1) | HRP20100624T8 (es) |
IL (1) | IL184524A0 (es) |
MX (1) | MX2007008790A (es) |
PA (1) | PA8660301A1 (es) |
PE (1) | PE20061119A1 (es) |
PL (1) | PL1845978T3 (es) |
PT (1) | PT1845978E (es) |
RU (1) | RU2375360C2 (es) |
SI (1) | SI1845978T1 (es) |
TW (1) | TW200639173A (es) |
UY (1) | UY29341A1 (es) |
WO (1) | WO2006077319A1 (es) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2871158A1 (fr) | 2004-06-04 | 2005-12-09 | Aventis Pharma Sa | Indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
FR2889526B1 (fr) | 2005-08-04 | 2012-02-17 | Aventis Pharma Sa | 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
TW200815438A (en) * | 2006-06-13 | 2008-04-01 | Bayer Schering Pharma Ag | Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
EP1870410A1 (en) | 2006-06-13 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
EP1932845A1 (en) * | 2006-12-15 | 2008-06-18 | Bayer Schering Pharma Aktiengesellschaft | 3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
EP2042500A1 (en) * | 2007-09-21 | 2009-04-01 | Bayer Schering Pharma Aktiengesellschaft | N-[4-(1-H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-N'-[(hetero)aryl]-urea compounds, pharmaceutical compositions comprising them, their preparation and their use as Tie2-kinase inhibitors |
WO2008071456A2 (en) * | 2006-12-15 | 2008-06-19 | Bayer Schering Pharma Aktiengesellschaft | 3-h-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
US20110160232A1 (en) * | 2007-10-04 | 2011-06-30 | Pingda Ren | Certain chemical entities and therapeutic uses thereof |
EP2215089B1 (en) * | 2007-11-02 | 2012-06-27 | Vertex Pharmaceuticals Incorporated | [1h- pyrazolo [3, 4-b]pyridine-4-yl]-phenyle or -pyridin-2-yle derivatives as protein kinase c-theta |
EP2070929A1 (en) | 2007-12-11 | 2009-06-17 | Bayer Schering Pharma Aktiengesellschaft | Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
CN101959887B (zh) | 2008-01-08 | 2013-07-31 | 阵列生物制药公司 | 作为激酶抑制剂的吡咯并吡啶 |
US8372842B2 (en) | 2008-01-09 | 2013-02-12 | Array Biopharma Inc. | Pyrazolopyridines as kinase inhibitors |
US8993580B2 (en) | 2008-03-14 | 2015-03-31 | Intellikine Llc | Benzothiazole kinase inhibitors and methods of use |
US8637542B2 (en) * | 2008-03-14 | 2014-01-28 | Intellikine, Inc. | Kinase inhibitors and methods of use |
CA2730106A1 (en) | 2008-07-08 | 2010-01-14 | Intellikine, Inc. | Kinase inhibitors and methods of use |
US8476431B2 (en) * | 2008-11-03 | 2013-07-02 | Itellikine LLC | Benzoxazole kinase inhibitors and methods of use |
RU2011142182A (ru) * | 2009-03-19 | 2013-04-27 | Медикал Рисерч Каунсил Текнолоджи | Соединения |
US8846673B2 (en) | 2009-08-11 | 2014-09-30 | Bristol-Myers Squibb Company | Azaindazoles as kinase inhibitors and use thereof |
US8222416B2 (en) * | 2009-12-14 | 2012-07-17 | Hoffmann-La Roche Inc. | Azaindole glucokinase activators |
GB201008134D0 (en) * | 2010-05-14 | 2010-06-30 | Medical Res Council Technology | Compounds |
WO2012015723A1 (en) | 2010-07-26 | 2012-02-02 | Bristol-Myers Squibb Company | Sulfonamide compounds useful as cyp17 inhibitors |
GB201015949D0 (en) | 2010-09-22 | 2010-11-03 | Medical Res Council Technology | Compounds |
CN103328473A (zh) | 2010-11-12 | 2013-09-25 | 百时美施贵宝公司 | 取代的氮杂吲唑化合物 |
EP2678018A4 (en) | 2011-02-23 | 2015-09-30 | Intellikine Llc | COMBINATION OF CHINESE HEMMER AND USES THEREOF |
US20140161720A1 (en) * | 2011-05-26 | 2014-06-12 | The General Hospital Corporation | Treatment of angiogenic- or vascular-associated diseases |
BR112014003296A2 (pt) * | 2011-08-12 | 2017-03-14 | Hoffmann La Roche | composto, composição farmacêutica, processo para a preparação de uma composição farmacêutica, método para o tratamento de uma doença ou distúrbio, conjunto para o tratamento de uma condição mediada pela quinase pim e utilização do composto |
EP2818473A4 (en) * | 2012-02-20 | 2015-04-15 | Takeda Pharmaceutical | HETEROCYCLIC COMPOUND |
US9233979B2 (en) * | 2012-09-28 | 2016-01-12 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
BR112015015477B1 (pt) * | 2012-12-28 | 2022-07-12 | Crystalgenomics, Inc | Derivados de 2,3-di-hidro-isoindol-1-ona e métodos de uso dos mesmos como inibidores de btk |
TWI629275B (zh) * | 2013-03-13 | 2018-07-11 | 賽諾菲公司 | N-(4-(氮雜吲唑-6-基)-苯基)-磺醯胺及其作為醫藥之用途 |
CN103524421B (zh) * | 2013-09-29 | 2015-04-01 | 镇江蓝德特药业科技有限公司 | 新型萘脲类衍生物及其医疗应用 |
SG11202008162WA (en) | 2018-04-05 | 2020-09-29 | Merck Patent Gmbh | Heteroaryl compounds as type ii irak inhibitors and uses hereof |
UY38349A (es) | 2018-08-30 | 2020-03-31 | Array Biopharma Inc | Compuestos de pirazolo[3,4-b]piridina como inhibidores de cinasas tam y met |
WO2023115142A1 (en) * | 2021-12-22 | 2023-06-29 | Anaxis Pharma Pty Ltd | Arylsulphonamide compounds |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1182896B (de) * | 1963-04-02 | 1964-12-03 | Merck Ag E | Fungizide Mittel |
DE60037455T2 (de) | 1999-09-17 | 2008-11-27 | Abbott Gmbh & Co. Kg | Kinaseinhibitoren als arzneimittel |
MXPA03000436A (es) * | 2000-07-18 | 2003-06-24 | Yamanouchi Pharma Co Ltd | Medicamentos que compreden derivados de dicianopiridina. |
DE60143041D1 (de) * | 2000-08-10 | 2010-10-21 | Pfizer Italia Srl | Bizyklische pyrazole wirksam als kinase inhibitoren, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
JP4272338B2 (ja) * | 2000-09-22 | 2009-06-03 | バイエル アクチェンゲゼルシャフト | ピリジン誘導体 |
FR2827603B1 (fr) * | 2001-07-18 | 2003-10-17 | Oreal | Composes derives de diaminopyrazole substitues par un radical heteroaromatique et leur utilisation en teinture d'oxydation des fibres keratiniques |
GB0128287D0 (en) * | 2001-11-26 | 2002-01-16 | Smithkline Beecham Plc | Novel method and compounds |
EP1534389A2 (en) * | 2002-07-23 | 2005-06-01 | SmithKline Beecham Corporation | Pyrazolopyrimidines as kinase inhibitors |
AU2003259749A1 (en) * | 2002-08-12 | 2004-02-25 | Sugen, Inc. | 3-pyrrolyl-pyridopyrazoles and 3-pyrrolyl-indazoles as novel kinase inhibitors |
NZ541836A (en) * | 2003-02-27 | 2008-12-24 | Palau Pharma Sa | Pyrazolopyridine derivatives |
JP2006524254A (ja) | 2003-04-24 | 2006-10-26 | メルク エンド カムパニー インコーポレーテッド | Akt活性の阻害剤 |
ES2346538T3 (es) * | 2003-05-22 | 2010-10-18 | Abbott Laboratories | Inhibidores de quinasa de tipo indazol, benzisoxazol y benzisotiazol. |
US7872014B2 (en) | 2003-07-23 | 2011-01-18 | Exelixis, Inc. | Anaplastic lymphoma kinase modulators and methods of use |
JP2005325099A (ja) * | 2004-04-12 | 2005-11-24 | Sankyo Co Ltd | チエノピリジン誘導体 |
US20060074102A1 (en) * | 2004-05-14 | 2006-04-06 | Kevin Cusack | Kinase inhibitors as therapeutic agents |
FR2871158A1 (fr) | 2004-06-04 | 2005-12-09 | Aventis Pharma Sa | Indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
WO2006050109A2 (en) * | 2004-10-29 | 2006-05-11 | Abbott Laboratories | Novel kinase inhibitors |
US7563781B2 (en) | 2005-01-14 | 2009-07-21 | Janssen Pharmaceutica Nv | Triazolopyrimidine derivatives |
EP1683796A1 (en) * | 2005-01-24 | 2006-07-26 | Schering Aktiengesellschaft | Pyrazolopyridines, their preparation and their medical use |
JP2008533032A (ja) | 2005-03-10 | 2008-08-21 | シージーアイ ファーマシューティカルズ,インコーポレイティド | 或る種の置換アミド、その製造方法及び使用方法 |
FR2889526B1 (fr) | 2005-08-04 | 2012-02-17 | Aventis Pharma Sa | 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation |
KR20080067339A (ko) | 2005-11-09 | 2008-07-18 | 메모리 파마슈티칼스 코포레이션 | 1h-인다졸, 벤조티아졸, 1,2-벤조이속사졸,1,2-벤조이소티아졸, 및 크로몬 및 그들의 제조법 및 용도 |
TW200815437A (en) * | 2006-06-13 | 2008-04-01 | Bayer Schering Pharma Ag | Substituted aminopyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
TW200815438A (en) * | 2006-06-13 | 2008-04-01 | Bayer Schering Pharma Ag | Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
EP1870410A1 (en) * | 2006-06-13 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
-
2006
- 2006-01-16 PE PE2006000065A patent/PE20061119A1/es not_active Application Discontinuation
- 2006-01-17 AR ARP060100172A patent/AR052357A1/es unknown
- 2006-01-18 PT PT06709121T patent/PT1845978E/pt unknown
- 2006-01-18 CA CA002595041A patent/CA2595041A1/fr not_active Abandoned
- 2006-01-18 SI SI200630831T patent/SI1845978T1/sl unknown
- 2006-01-18 RU RU2007131274/04A patent/RU2375360C2/ru not_active IP Right Cessation
- 2006-01-18 MX MX2007008790A patent/MX2007008790A/es not_active Application Discontinuation
- 2006-01-18 WO PCT/FR2006/000114 patent/WO2006077319A1/fr active Application Filing
- 2006-01-18 EP EP06709121A patent/EP1845978B1/fr not_active Revoked
- 2006-01-18 BR BRPI0606504-0A patent/BRPI0606504A2/pt not_active IP Right Cessation
- 2006-01-18 KR KR1020077018866A patent/KR20070098923A/ko not_active Application Discontinuation
- 2006-01-18 AT AT06709121T patent/ATE477799T1/de active
- 2006-01-18 AU AU2006207442A patent/AU2006207442A1/en not_active Abandoned
- 2006-01-18 PL PL06709121T patent/PL1845978T3/pl unknown
- 2006-01-18 JP JP2007551703A patent/JP2008527025A/ja active Pending
- 2006-01-18 DE DE602006016233T patent/DE602006016233D1/de active Active
- 2006-01-18 TW TW095101823A patent/TW200639173A/zh unknown
- 2006-01-18 DK DK06709121.5T patent/DK1845978T3/da active
- 2006-01-19 PA PA20068660301A patent/PA8660301A1/es unknown
- 2006-01-19 UY UY29341A patent/UY29341A1/es unknown
-
2007
- 2007-07-10 IL IL184524A patent/IL184524A0/en unknown
- 2007-07-17 US US11/778,870 patent/US8008322B2/en active Active
-
2010
- 2010-11-18 HR HR20100624T patent/HRP20100624T8/xx unknown
- 2010-11-18 CY CY20101101043T patent/CY1110926T1/el unknown
-
2011
- 2011-04-11 US US13/084,077 patent/US20110190337A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AR052357A1 (es) | 2007-03-14 |
SI1845978T1 (sl) | 2010-12-31 |
PL1845978T3 (pl) | 2011-02-28 |
HRP20100624T8 (en) | 2011-01-31 |
AU2006207442A1 (en) | 2006-07-27 |
EP1845978A1 (fr) | 2007-10-24 |
PA8660301A1 (es) | 2006-09-08 |
US8008322B2 (en) | 2011-08-30 |
DK1845978T3 (da) | 2010-12-13 |
JP2008527025A (ja) | 2008-07-24 |
IL184524A0 (en) | 2007-10-31 |
UY29341A1 (es) | 2006-08-31 |
KR20070098923A (ko) | 2007-10-05 |
US20080039491A1 (en) | 2008-02-14 |
CA2595041A1 (fr) | 2006-07-27 |
WO2006077319A1 (fr) | 2006-07-27 |
PE20061119A1 (es) | 2006-11-27 |
RU2007131274A (ru) | 2009-02-27 |
PT1845978E (pt) | 2010-11-29 |
HRP20100624T1 (hr) | 2010-12-31 |
ATE477799T1 (de) | 2010-09-15 |
RU2375360C2 (ru) | 2009-12-10 |
BRPI0606504A2 (pt) | 2009-06-30 |
TW200639173A (en) | 2006-11-16 |
US20110190337A1 (en) | 2011-08-04 |
EP1845978B1 (fr) | 2010-08-18 |
DE602006016233D1 (de) | 2010-09-30 |
CY1110926T1 (el) | 2015-06-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2007008790A (es) | Pirazolo piridinas sustituidas, composiciones que las contienen, metodo de produccion de las mismas, y su uso. | |
TNSN07360A1 (en) | Substituted pyrrolo-pyridines, composition containing them, method for their producing and use thereof | |
UA94417C2 (ru) | Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение | |
PH12013502192A1 (en) | Antibodies against human angiopoietin 2 | |
TW200745114A (en) | Novel compounds | |
TW200800999A (en) | Novel compounds | |
MX2011011661A (es) | Compuestos 1-cianoetilheterociclilcarboxamida sustituidos 750. | |
TW200612892A (en) | Novel compounds | |
PL1891004T3 (pl) | Pentafluorosulfanylo-podstawiony związek i jego zastosowanie do wytwarzania środków leczniczych | |
TW200745003A (en) | Novel compounds | |
WO2008046581A3 (de) | Substituierte tetrahydropyrrolopyrazin-verbindungen als inhibitoren der monoaminwiederaufnahme und deren verwendung in arzeimitteln | |
TW200640857A (en) | Substituted pyrroles and imidazoles, compositions containing same, manufacturing process therefor and use thereof | |
TW200634007A (en) | Substituted indoles, compositions containing them, production process and use | |
TW200738659A (en) | Novel compounds | |
TW200745084A (en) | Novel compounds | |
TW200730518A (en) | Crystalline forms of docetaxel and processes for their preparation | |
TNSN08321A1 (en) | Dimers of artemisinin derivatives, preparation thereof and therapeutic use thereof | |
TW200630343A (en) | 2-Alkoxy-3,4,5-trihydroxy-alkylamides, preparation thereof, compositions containing them and use thereof | |
MX2007006042A (es) | Bengamidas que poseen un ciclo caprolactama sustituido, procedimiento de preparacion, composiciones que las contienen y utilizacion. | |
TW200718698A (en) | Process for preparing new tiotropium salts, new tiotropium salts as such and pharmaceutical compositions thereof | |
MX2009000768A (es) | Lactamas macrociclicas. | |
TW200640858A (en) | Substituted pyrroles, compositions containing them, method of manufacture and use | |
MX2009003459A (es) | Derivados de 2,3,3-trimetilciclopent-3-encarbaldehido utiles como odorantes. | |
GB0615105D0 (en) | Novel compounds | |
TW200633717A (en) | Process for and intermediates in the preparation of canfosfamide and its salts, pharmaceutical compositions containing some intermediates, and their use as anticancer agents |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |