PE20142380A1 - Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo - Google Patents

Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo

Info

Publication number
PE20142380A1
PE20142380A1 PE2014002012A PE2014002012A PE20142380A1 PE 20142380 A1 PE20142380 A1 PE 20142380A1 PE 2014002012 A PE2014002012 A PE 2014002012A PE 2014002012 A PE2014002012 A PE 2014002012A PE 20142380 A1 PE20142380 A1 PE 20142380A1
Authority
PE
Peru
Prior art keywords
fatty acid
highly
highly unsaturated
ethyl ester
unsaturated fatty
Prior art date
Application number
PE2014002012A
Other languages
English (en)
Inventor
Nobushige Doisaki
Kazuhiko Hata
Shinji Tokiwa
Kazunori Matsushima
Original Assignee
Nippon Suisan Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49583751&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20142380(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nippon Suisan Kaisha Ltd filed Critical Nippon Suisan Kaisha Ltd
Publication of PE20142380A1 publication Critical patent/PE20142380A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D3/00—Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
    • B01D3/14—Fractional distillation or use of a fractionation or rectification column
    • B01D3/143—Fractional distillation or use of a fractionation or rectification column by two or more of a fractionation, separation or rectification step
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C07C51/44—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/47—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C07C57/12—Straight chain carboxylic acids containing eighteen carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation
    • C07C67/54—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation by distillation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/56—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/12—Refining fats or fatty oils by distillation
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
    • C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
    • C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/003—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with alcohols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/02—Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/612—Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B3/00—Refining fats or fatty oils
    • C11B3/16—Refining fats or fatty oils by mechanical means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Nutrition Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
  • Edible Oils And Fats (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)

Abstract

Referida a un acido graso altamente insaturado o un ester etilico de acido graso altamente insaturado, que ha sido producido utilizando como aceite de materia prima una grasa o aceite que contiene acidos grasos altamente insaturados como constituyentes de los acidos grasos y el cual ha sido reducido en el contenido de contaminantes ambientales, en donde entre las dioxinas contenidas, dibenzoparadioxinas policloradas (PCDD) y dibenzofuranos policlorados (PCDF) estan contenidos, en cantidades de menos de 0,05 pg-TEQ/g y PCB coplanares (Co-PCB) en cantidades de menos de 0,03 pg-TEQ/g. Tambien esta referida a un metodo para producir el acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, por medio de las etapas de remover acidos grasos libres y contaminantes ambientales por medio de la destinacion de pelicula fina de aceite de materia prima, esterificado etilico del aceite o grasa resultante y refinado del mismo, por medio de rectificacion y columna de cromatografia
PE2014002012A 2012-05-14 2013-05-14 Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo PE20142380A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012110809 2012-05-14

Publications (1)

Publication Number Publication Date
PE20142380A1 true PE20142380A1 (es) 2015-01-21

Family

ID=49583751

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2019001187A PE20190969A1 (es) 2012-05-14 2013-05-14 Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo
PE2014002012A PE20142380A1 (es) 2012-05-14 2013-05-14 Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2019001187A PE20190969A1 (es) 2012-05-14 2013-05-14 Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo

Country Status (13)

Country Link
US (6) US9540306B2 (es)
EP (3) EP3971165B1 (es)
JP (8) JP5592570B2 (es)
KR (7) KR102117725B1 (es)
CN (5) CN113045422A (es)
CA (2) CA2873160C (es)
CL (1) CL2014003053A1 (es)
DE (1) DE202013012875U1 (es)
DK (1) DK2851361T3 (es)
ES (1) ES2900618T3 (es)
HU (1) HUE057283T2 (es)
PE (2) PE20190969A1 (es)
WO (1) WO2013172346A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102117725B1 (ko) * 2012-05-14 2020-06-01 닛폰 스이산 가부시키가이샤 환경 오염 물질을 저감시킨 고도 불포화 지방산 또는 고도 불포화 지방산 에틸에스테르 및 그 제조 방법
WO2014068056A1 (en) 2012-11-02 2014-05-08 Pronova Biopharma Norge As Removal of undesired components from oil compositions
US11330817B2 (en) * 2013-12-04 2022-05-17 Nippon Suisan Kaisha, Ltd. Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil
SG10201912618XA (en) 2015-08-31 2020-02-27 Nippon Suisan Kaisha Ltd Free polyunsaturated fatty acid-containing composition and manufacturing method therefor
ITUB20153877A1 (it) * 2015-09-24 2017-03-24 Tiberio Bruzzese Metodo di purificazione di gliceridi di acidi grassi, composizioni che ne derivano, e loro uso
CN106349070A (zh) * 2016-08-31 2017-01-25 山东康曼生物科技有限公司 一种从低含量乙酯鱼油生产欧米加‑3‑酸乙酯90的工艺
JP6987129B2 (ja) * 2016-09-23 2021-12-22 シージェイ チェイルジェダン コーポレイション 脂肪酸エチルエステルの製造方法
EP3649219B1 (en) * 2017-07-07 2022-10-05 Bunge Loders Croklaan B.V. Process for the preparation of a hydrogenated fat composition
CN109438220B (zh) * 2018-10-31 2021-04-13 苏州赛分科技有限公司 一种从鱼油中纯化epa的方法
EP3904328A4 (en) 2018-12-26 2022-10-05 Nisshin Pharma Inc. COMPOSITION CONTAINING AN ALKYL ESTER OF EICOSAPENTAENOIC ACID AND METHOD FOR PRODUCTION
CN111302940A (zh) * 2020-04-08 2020-06-19 燕园泽龙(涿鹿)生物科技有限公司 高纯度α-亚麻酸乙酯的生产方法
JP7289994B2 (ja) * 2021-03-17 2023-06-12 株式会社ニッスイ 精製の方法および精製された製品
CN114057574A (zh) * 2021-12-03 2022-02-18 浙江工商大学 一种制备高纯度epa乙酯的方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57149400A (en) 1981-03-12 1982-09-14 Kureha Chemical Ind Co Ltd Manufacture of high purity long chain highly unsaturated fatty acid ester
JPS5888339A (ja) 1981-11-20 1983-05-26 Kagakuhin Kensa Kyokai エイコサペンタエン酸又はそのエステルとドコサヘキサエン酸又はそのエステルの分離精製方法
NL8200559A (nl) 1982-02-15 1983-09-01 Ir Jan Bart Le Poole Prof Dr Bestralingsinrichting met bundelsplitsing.
JPS60208940A (ja) 1984-03-31 1985-10-21 Nippon Zeon Co Ltd 長鎮不飽和脂肪酸化合物の分離精製法
GB8819110D0 (en) 1988-08-11 1988-09-14 Norsk Hydro As Antihypertensive drug & method for production
JPH0633088B2 (ja) 1990-02-20 1994-05-02 金沢樹脂工業株式会社 組立式フォークリフト用パレット
CA2043615C (en) 1990-06-04 2001-08-14 Kazuhiko Hata Method of producing eicosapentaenoic acid or the ester derivative thereof
JP3290152B2 (ja) 1990-06-04 2002-06-10 日本水産株式会社 高濃度エイコサペンタエン酸またはそのエステル
JPH07105223B2 (ja) 1991-03-11 1995-11-13 日本碍子株式会社 高温電池集合体
US5215630A (en) 1991-06-04 1993-06-01 Nippon Suisan Kaisha, Ltd. Method of purifying eicosapentaenoic acid or the ester derivative thereof by fractional distillation
JP2988754B2 (ja) 1991-09-03 1999-12-13 日本水産株式会社 高真空連続蒸留装置
JP3400466B2 (ja) 1991-10-28 2003-04-28 日本水産株式会社 高純度エイコサペンタエン酸またはそのエステルの製造方法
JP3614177B2 (ja) 1992-07-21 2005-01-26 日本水産株式会社 高純度ドコサヘキサエン酸またはそのエステルの 製造方法
GB9404483D0 (en) * 1994-03-08 1994-04-20 Norsk Hydro As Refining marine oil compositions
JPH08100191A (ja) * 1994-09-30 1996-04-16 Nisshin Flour Milling Co Ltd 高度不飽和脂肪酸またはそのエステルの精製方法
NO314788B1 (no) 1994-11-15 2003-05-26 K D Pharma Gmbh Framgangsmåte for utvinning av en eller flere forbindelser fra en blanding
JPH09302380A (ja) * 1996-05-10 1997-11-25 Nippon Wax Polymer Kaihatsu Kenkyusho:Kk エイコサペンタエン酸又はそのエステルの精製方法
JPH1095744A (ja) * 1996-09-20 1998-04-14 Nof Corp 高度不飽和脂肪酸又はそのアルキルエステルの製造方法
JPH10310551A (ja) * 1997-05-12 1998-11-24 Nippon Wax Polymer Kaihatsu Kenkyusho:Kk エイコサペンタエン酸又はそのエステルの精製方法
CN1072711C (zh) * 1998-01-05 2001-10-10 山东禹王制药有限公司 一种高度不饱和脂肪酸的工业化生产方法
JP2872986B1 (ja) * 1998-01-21 1999-03-24 池田食研株式会社 高純度高度不飽和脂肪酸の低級アルコールエステル精製方法
EP1084214B1 (en) * 1998-06-05 2006-08-30 MERCK PATENT GmbH Contaminant reduced marine oil
DE19923558A1 (de) 1999-05-21 2000-11-23 K D Pharma Bexbach Gmbh Verfahren zur Herstellung von geruchs- und geschmacksfreien ungesättigten Fettsäuren aus Naturölen und deren Verwendung
ES2159257B1 (es) 1999-11-19 2002-04-16 Kd Iqa S L Nuevo procedimiento de preparacion del ester etilico del acido eicosa pentaenoico.
EP1125914A1 (en) 2000-02-14 2001-08-22 Nisshin Flour Milling Co., Ltd. Process for separating and purifying eicosapentaenoic acid or its ester
CA2336513C (en) 2000-02-17 2010-08-24 Tatsuo Tateno Process for producing fatty acid esters and fuels comprising fatty acid ester
JP4752118B2 (ja) * 2000-02-17 2011-08-17 住友化学株式会社 脂肪酸エステルの製造方法および脂肪酸エステルを含む燃料
ES2264698T3 (es) * 2000-07-19 2007-01-16 Lysi Hf Metodo para la produccion de aceites marinos con niveles reducidos de contaminantes.
SE0202188D0 (sv) 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
FR2894772B1 (fr) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Procede d'enrichissement en dha
DE102006012866B4 (de) 2006-03-19 2009-04-09 Uic Gmbh Verfahren zur Abtrennung leichtflüchtiger Komponenten aus einem Stoffgemisch sowie Vorrichtung zur Durchführung dieses Verfahrens
WO2008133573A1 (en) * 2007-04-26 2008-11-06 Patrick Adlercreutz A polyunsaturated fatty acid (pufa) enriched marine oil comprising eicosapentaenoic acid (epa) and docosahexaenoic acid (dha), and a process of production thereof
EP2172558B1 (en) 2007-07-30 2017-07-19 Nippon Suisan Kaisha, Ltd. Method for production of epa-enriched oil and dha-enriched oil
SI2062484T1 (sl) 2007-11-23 2011-08-31 Reemtsma H F & Ph Postopek izdelave tobačnih izdelkov, ki se ne kadijo, in tobačni izdelek, ki se ne kadi, za oralno uporabo
CN107080734B (zh) 2008-03-20 2020-10-30 维尔恩公司 包含生育酚的peg衍生物的乳剂
US8829215B2 (en) 2008-05-15 2014-09-09 Pronova Biopharma Norge As Krill oil process
KR101357298B1 (ko) 2008-06-20 2014-01-28 에이케이 앤 엠엔 바이오팜 주식회사 오메가-3계 고도불포화 지방산의 고순도 정제방법
JP2010118383A (ja) * 2008-11-11 2010-05-27 Nikon Corp 照明装置、露光装置、及びデバイス製造方法
CN110538148A (zh) 2009-03-09 2019-12-06 巴斯夫股份公司 含有脂肪酸油混合物和表面活性剂的组合物及其方法和用途
CL2009001343A1 (es) * 2009-06-02 2009-07-10 Golden Omega S A Proceso de obtencion concentrado de esteres de epa y dha a partir de aceite marino, que comprende agregar al aceite alcali y agua a menos de 100 grados celsius, agregar solvente, separar fase de refinado, agregar acido, separar la fase no acuosa y agregar alcohol y un catalizador a menos de 150 grados celsius, desolventilizar y destilar.
EP2519332B1 (en) * 2009-12-30 2014-03-05 BASF Pharma (Callanish) Limited Simulated moving bed chromatographic separation process for the purification of polyunsaturated fatty acids
KR101622441B1 (ko) 2010-03-23 2016-05-18 버런, 아이엔씨. 자당 지방산 에스테르를 포함하는 나노에멀전
US20130123525A1 (en) 2010-05-28 2013-05-16 Nippon Suisan Kaisha, Ltd. Method for producing oil containing polyunsaturated fatty acid using lipase
US8769868B2 (en) * 2010-06-09 2014-07-08 Photonz Corporation Limited Compositions comprising eicosapentaenoic acid suitable for high purification
ES2700134T3 (es) 2010-09-24 2019-02-14 Basf As Procedimiento de concentración de ácidos grasos omega-3
JP5650506B2 (ja) 2010-11-22 2015-01-07 優章 荒井 電解水の製造装置
AU2012214260A1 (en) 2011-02-11 2013-07-25 E. I. Du Pont De Nemours And Company An eicosapentaenoic acid concentrate
GB201111591D0 (en) * 2011-07-06 2011-08-24 Equateq Ltd Further new process
ES2395320B1 (es) 2011-07-14 2013-12-18 Soluciones Extractivas Alimentarias, S.L. Nuevo método para la reducción de contaminantes en grasas y aceites a partir de aceites y sus derivados.
RU2014123063A (ru) * 2011-11-09 2015-12-20 Эвоник Мембрейн Экстрекшн Текнолоджи Лтд. Мембранный способ снижения по меньшей мере одной примеси и получения концентрата, содержащего по меньшей мере один природный компонент из смеси масел неморских жирных кислот, и получаемые композиции
US8258330B1 (en) 2012-01-04 2012-09-04 Naturalis, S.A. Carrier fluid composition comprising fatty acids ethyl esters and process for reducing the concentration of persistent organic pollutants in fish oil
KR102117725B1 (ko) * 2012-05-14 2020-06-01 닛폰 스이산 가부시키가이샤 환경 오염 물질을 저감시킨 고도 불포화 지방산 또는 고도 불포화 지방산 에틸에스테르 및 그 제조 방법
US11330817B2 (en) 2013-12-04 2022-05-17 Nippon Suisan Kaisha, Ltd. Microbial oil, production method for microbial oil, concentrated microbial oil, and production method for concentrated microbial oil

Also Published As

Publication number Publication date
US20210269388A1 (en) 2021-09-02
KR20150013257A (ko) 2015-02-04
CN113025434A (zh) 2021-06-25
CN107602378B (zh) 2021-06-25
CN104302615A (zh) 2015-01-21
JP2017190335A (ja) 2017-10-19
KR20220140655A (ko) 2022-10-18
EP2851361A4 (en) 2015-12-30
JP6309828B2 (ja) 2018-04-11
CL2014003053A1 (es) 2015-02-27
PE20190969A1 (es) 2019-07-08
US10399922B2 (en) 2019-09-03
DE202013012875U1 (de) 2021-01-15
KR102117725B1 (ko) 2020-06-01
JP2024069262A (ja) 2024-05-21
CN106810446A (zh) 2017-06-09
US20180305291A1 (en) 2018-10-25
JP6774469B2 (ja) 2020-10-21
CN104302615B (zh) 2017-09-08
JP2022132317A (ja) 2022-09-08
JPWO2013172346A1 (ja) 2016-01-12
KR102453616B1 (ko) 2022-10-11
EP3971165C0 (en) 2024-08-07
JP6434573B2 (ja) 2018-12-05
US11603347B2 (en) 2023-03-14
ES2900618T3 (es) 2022-03-17
JP5592570B2 (ja) 2014-09-17
CA2873160A1 (en) 2013-11-21
JP2019031507A (ja) 2019-02-28
US10399923B2 (en) 2019-09-03
JP2018111719A (ja) 2018-07-19
US20190337883A1 (en) 2019-11-07
CN113045422A (zh) 2021-06-29
WO2013172346A1 (ja) 2013-11-21
US9540306B2 (en) 2017-01-10
EP2851361A1 (en) 2015-03-25
KR20240096704A (ko) 2024-06-26
JP6389579B2 (ja) 2018-09-12
CA2873160C (en) 2024-02-27
CN107602378A (zh) 2018-01-19
US20170081272A1 (en) 2017-03-23
EP3971165A1 (en) 2022-03-23
KR20210030507A (ko) 2021-03-17
KR102381331B1 (ko) 2022-04-01
KR102229106B1 (ko) 2021-03-18
KR20200060531A (ko) 2020-05-29
US20230183165A1 (en) 2023-06-15
EP4414356A2 (en) 2024-08-14
HUE057283T2 (hu) 2022-04-28
CA3225865A1 (en) 2013-11-21
US20150126760A1 (en) 2015-05-07
US11034643B2 (en) 2021-06-15
JP2014231513A (ja) 2014-12-11
EP2851361B1 (en) 2021-11-24
EP3971165B1 (en) 2024-08-07
KR102117806B1 (ko) 2020-06-01
KR20220044387A (ko) 2022-04-07
KR20200023557A (ko) 2020-03-04
JP2021004254A (ja) 2021-01-14
DK2851361T3 (da) 2022-01-03

Similar Documents

Publication Publication Date Title
PE20142380A1 (es) Acido graso altamente insaturado o ester etilico de acido graso altamente insaturado, con reducidos contaminantes ambientales, y metodo para producir el mismo
MY183587A (en) Process for the purification of a fatty acid alkyl ester by liquid/liquid extraction
PE20130491A1 (es) Proceso simulado de separacion cromatografica de lecho movil para la purificacion de acidos grasos poliinsaturados
MY164889A (en) Purification of unrefined edible oils and fats with magnesium silicate and organic acids
CL2012003376A1 (es) Proceso para remover lignina de licor negro acidificando el licor negro, en donde el licor negro es oxidado antes de dicha acidificacion para minimizar elazufre reducido total (trs) en el licor negro, de manera que las hemicelulosas sean oxidadas para formar un agente de acidificacion, el cual complementa a dicho acidificante en la acidificacion; proceso para separar lignina de licor negro.
AR098895A1 (es) Proceso para obtener aceite microbiano a partir de células microbianas
CL2011002745A1 (es) Compuestos derivados de acidos grasos poliinsaturados; metodo de preparacion; composicion farmaceutica que los comprende; y su uso para la prevencion o el tratamiento de trastornos cardiovasculares, metabolicos e inflamatorios, tales como, artritis reumatoide, aterosclerosis, diabetes, dislipidemia, entre otras.
WO2013102800A9 (en) Carrier fluid composition comprising fatty acids ethyl esters and process for reducing the concentration of persistent organic pollutants in fish oil
CL2013002183A1 (es) Metodo de manufactura de una estructura de didipacion de claor para un led que comprende: d9 colocar la palaca de conducccion de calo (6) y la terjeta pcb (4)
PE20151044A1 (es) Retiro de componentes indeseados de las composiciones de aceite
AR098896A1 (es) Proceso para obtener aceite microbiano a partir de células microbianas
CL2007003630A1 (es) Composicion farmaceutica que comprende vitamina c, vitamina e, luteina, zinc, acido graso omega-3 y cobre; metodo de elaboracion; y uso para el tratamiento y/o prevencion de la degeneracion macular relacionada con la edad (amd) y/o retinopatia diabet
BR112014010347A2 (pt) óleo contendo ácido graxo poliinsaturado oxidativamente estável
FR2955459B1 (fr) Composition huileuse riche en monoglycerides de dha
BR112014013593A8 (pt) retenção de dha durante o processamento de óleo de canola
BR112016017107B8 (pt) Coluna de destilação
AR083259A1 (es) Cuantificacion y caracterizacion de los alergenos
BR112015023315A2 (pt) método para remover um contaminante de uma composição biológica que contém contaminante útil como matéria-prima de biocombustível
CR20120381A (es) Composiciones nutricionales que comprenden hojuelas de frutas que incluyen acido docosahexaenoico
BR112013018954A2 (pt) utilização de pelo menos um coproduto da indústria de refinação dos óleos vegetais para se obter um insaponificável total purificado de óleo vegetal.
CO2017007007A2 (es) Análogos de calcitonina
MX349987B (es) Emulsión orgánica que comprende dha y epa.
AR091873A1 (es) Intraesterificacion 1,3-especifica
PH12015501128A1 (en) Illuminated frame system
BR112015012026A2 (pt) método para isolamento de ácido chiquímico a partir do material residual do dendezeiro

Legal Events

Date Code Title Description
FG Grant, registration