CO2017007007A2 - Análogos de calcitonina - Google Patents

Análogos de calcitonina

Info

Publication number
CO2017007007A2
CO2017007007A2 CONC2017/0007007A CO2017007007A CO2017007007A2 CO 2017007007 A2 CO2017007007 A2 CO 2017007007A2 CO 2017007007 A CO2017007007 A CO 2017007007A CO 2017007007 A2 CO2017007007 A2 CO 2017007007A2
Authority
CO
Colombia
Prior art keywords
analogs
calcitonin
relates
present
calcitonins
Prior art date
Application number
CONC2017/0007007A
Other languages
English (en)
Inventor
Morten Karsdal
Kim Henriksen
Kim Vietz Andreassen
Sofie Gydesen
Sara Toftegaard Hjuler
Original Assignee
Keybioscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keybioscience Ag filed Critical Keybioscience Ag
Publication of CO2017007007A2 publication Critical patent/CO2017007007A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

Las calcitoninas de origen natural de varias especies y análogos de las calcitoninas naturales han sido propuestos como medicamentos en el tratamiento de diversas enfermedades y trastornos. La presente invención se relaciona con análogos La presente invención se refiere a análogos o miméticos de calcitonina, y su uso en la reducción de la acumulación de grasas en el hígado de los sujetos.
CONC2017/0007007A 2015-01-08 2017-07-12 Análogos de calcitonina CO2017007007A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1500263.7A GB201500263D0 (en) 2015-01-08 2015-01-08 Calcitonin analogues for treating diseases and disorders
PCT/EP2016/050186 WO2016110525A1 (en) 2015-01-08 2016-01-07 Calcitonin analogues for treating diseases and disorders

Publications (1)

Publication Number Publication Date
CO2017007007A2 true CO2017007007A2 (es) 2018-01-31

Family

ID=52597359

Family Applications (1)

Application Number Title Priority Date Filing Date
CONC2017/0007007A CO2017007007A2 (es) 2015-01-08 2017-07-12 Análogos de calcitonina

Country Status (17)

Country Link
US (2) US10350272B2 (es)
EP (1) EP3247383A1 (es)
JP (1) JP2018502854A (es)
KR (1) KR20170120576A (es)
CN (1) CN107206056A (es)
AU (1) AU2016205994A1 (es)
BR (1) BR112017014552A2 (es)
CA (1) CA2969293A1 (es)
CL (1) CL2017001773A1 (es)
CO (1) CO2017007007A2 (es)
EA (1) EA201791154A1 (es)
GB (1) GB201500263D0 (es)
IL (1) IL253026A0 (es)
MX (1) MX2017008755A (es)
PE (1) PE20171320A1 (es)
PH (1) PH12017500988A1 (es)
WO (1) WO2016110525A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201704429D0 (en) * 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) * 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
GB201813678D0 (en) * 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) * 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders

Family Cites Families (32)

* Cited by examiner, † Cited by third party
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US6319685B1 (en) 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
US5789234A (en) 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US5102666A (en) 1990-09-11 1992-04-07 Oramed, Inc. Calcium polycarbophil controlled release composition and method
US5359030A (en) 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
US6692766B1 (en) 1994-06-15 2004-02-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Controlled release oral drug delivery system
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
US5773647A (en) 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
EP1137431A1 (en) 1998-12-04 2001-10-04 Provalis UK Limited Pharmaceutical compositions containing insulin
DE60017888T2 (de) 1999-04-05 2006-01-19 Emisphere Technologies, Inc. Dinatrium-salze, monohydrate und ethanol-solvate
US6780846B1 (en) 1999-09-27 2004-08-24 Elan Corporation, Plc Membrane translocating peptide drug delivery system
GB2368792A (en) 2000-10-06 2002-05-15 Roger Randal Charles New Absorption enhancers
US6673574B2 (en) 2000-11-30 2004-01-06 Unigene Laboratories Inc. Oral delivery of peptides using enzyme-cleavable membrane translocators
US7316819B2 (en) 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
EP1608347B1 (en) 2003-03-28 2014-08-13 Sigmoid Pharma Limited Solid oral dosage form containing seamless microcapsules
GB0308732D0 (en) 2003-04-15 2003-05-21 Axcess Ltd Absorption enhancers
BRPI0412265A (pt) 2003-07-23 2006-09-05 Novartis Ag uso de calcitonina em osteoartrite
EP1670500A2 (en) 2003-09-17 2006-06-21 Chiasma, Ltd. Compositions capable of facilitating penetration across a biological barrier
CA2574232A1 (en) 2004-07-22 2006-01-26 Thiomatrix Forschungs - Und Beratungs Gmbh Use of compounds containing thiol groups as an efflux pump inhibitor
US7445911B2 (en) 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids
EP1907561B1 (en) 2005-06-24 2013-08-28 Unigene Laboratories, Inc. Cell lines for expressing enzyme useful in the preparation of amidated products
EP2722054B1 (en) 2005-09-06 2018-03-21 Oramed Pharmaceuticals Inc. Methods and compositions for oral administration of proteins
US8093207B2 (en) 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
DK1834635T3 (da) 2006-03-13 2011-10-24 Advancell Advanced In Vitro Cell Technologies S A Stabile nanokapselsystemer til administrtion af aktive molekyler
KR101191322B1 (ko) 2006-04-07 2012-10-16 메리온 리서치 Ⅲ 리미티드 증진제를 함유하는 고형 경구용 투여 제형
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
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ES2622877T3 (es) * 2009-01-22 2017-07-07 Keybioscience Ag Tratamiento para la obesidad
JP6170933B2 (ja) 2011-11-02 2017-07-26 キーバイオサイエンス・アクチエンゲゼルシャフト ペプチドの使用
DK3068796T3 (en) * 2013-11-14 2018-03-05 Keybioscience Ag CALCITONIN MIMETICS FOR THE TREATMENT OF DISEASES AND DISORDERS

Also Published As

Publication number Publication date
CA2969293A1 (en) 2016-07-14
AU2016205994A1 (en) 2017-06-15
EP3247383A1 (en) 2017-11-29
EA201791154A1 (ru) 2017-09-29
CN107206056A (zh) 2017-09-26
PH12017500988A1 (en) 2017-12-18
KR20170120576A (ko) 2017-10-31
MX2017008755A (es) 2017-11-17
GB201500263D0 (en) 2015-02-25
WO2016110525A1 (en) 2016-07-14
BR112017014552A2 (pt) 2018-05-15
IL253026A0 (en) 2017-08-31
CL2017001773A1 (es) 2018-03-09
US20190328843A1 (en) 2019-10-31
US10350272B2 (en) 2019-07-16
JP2018502854A (ja) 2018-02-01
US20180264085A1 (en) 2018-09-20
PE20171320A1 (es) 2017-09-07

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