DK1834635T3 - Stabile nanokapselsystemer til administrtion af aktive molekyler - Google Patents

Stabile nanokapselsystemer til administrtion af aktive molekyler

Info

Publication number
DK1834635T3
DK1834635T3 DK06380048.6T DK06380048T DK1834635T3 DK 1834635 T3 DK1834635 T3 DK 1834635T3 DK 06380048 T DK06380048 T DK 06380048T DK 1834635 T3 DK1834635 T3 DK 1834635T3
Authority
DK
Denmark
Prior art keywords
administration
active molecules
stable
nanocapsule systems
stable nanocapsule
Prior art date
Application number
DK06380048.6T
Other languages
English (en)
Inventor
Rez Luque Silvia Sua
Ferna Ndez M Alonso
Pena Ana Isabel Vila
Original Assignee
Advancell Advanced In Vitro Cell Technologies S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advancell Advanced In Vitro Cell Technologies S A filed Critical Advancell Advanced In Vitro Cell Technologies S A
Application granted granted Critical
Publication of DK1834635T3 publication Critical patent/DK1834635T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK06380048.6T 2006-03-13 2006-03-13 Stabile nanokapselsystemer til administrtion af aktive molekyler DK1834635T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06380048A EP1834635B1 (en) 2006-03-13 2006-03-13 Stable nanocapsule systems for the administration of active molecules

Publications (1)

Publication Number Publication Date
DK1834635T3 true DK1834635T3 (da) 2011-10-24

Family

ID=36743270

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06380048.6T DK1834635T3 (da) 2006-03-13 2006-03-13 Stabile nanokapselsystemer til administrtion af aktive molekyler

Country Status (17)

Country Link
US (1) US20090074824A1 (da)
EP (1) EP1834635B1 (da)
JP (1) JP5222739B2 (da)
KR (1) KR20080102303A (da)
CN (1) CN101426479B (da)
AR (1) AR059829A1 (da)
AT (1) ATE515260T1 (da)
AU (1) AU2007224471B2 (da)
BR (1) BRPI0709594A2 (da)
CA (1) CA2646338A1 (da)
DK (1) DK1834635T3 (da)
ES (1) ES2369244T3 (da)
IL (1) IL194005A0 (da)
PE (1) PE20080141A1 (da)
PL (1) PL1834635T3 (da)
PT (1) PT1834635E (da)
WO (1) WO2007104732A2 (da)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2848648C (en) 2006-06-02 2017-10-10 Synedgen, Inc. Chitosan-derivative compounds and methods of controlling microbial populations
US20080248508A1 (en) * 2006-08-17 2008-10-09 Shenda Baker Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials
US20100203163A1 (en) * 2007-06-12 2010-08-12 Christine Allen Injectable polymer-lipid blend for localized drug delivery
PL2200588T3 (pl) * 2007-09-25 2019-09-30 Solubest Ltd. Kompozycje zawierające lipofilowe związki aktywne i sposób ich wytwarzania
EP2042166A1 (en) * 2007-09-25 2009-04-01 The Jordanian Pharmaceutical Manufacturing Co. Nanocapsules for oral delivery of proteins
KR101199580B1 (ko) * 2008-08-06 2013-11-27 (주)에델프라우 국소 투여용 나노에멀젼
BRPI0805854A2 (pt) * 2008-10-10 2010-08-24 Biolab Sanus Farmaceutica Ltda sistema nanoparticulado, processo de preparaÇço do mesmo, uso do mesmo, composiÇço fotoproterora, processo de preparaÇço da mesma, mÉtodo de prevenÇço de doenÇas e distérbios da pele
TWI328565B (en) * 2008-12-19 2010-08-11 Taiwan Textile Res Inst Dispersions of conductive carbon materials and methods for preparing the same
NZ595021A (en) 2009-03-12 2013-04-26 Nordic Bioscience As Treatment of diabetes and metabolic syndrome with enteral formulations of calcitonin peptides or calcitonin receptor agonists
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
EP2266546A1 (en) * 2009-06-08 2010-12-29 Advancell Advanced in Vitro Cell Technologies,S.A. Process for the preparation of colloidal systems for the delivery of active compounds
EP2364600A1 (en) * 2010-02-18 2011-09-14 Nestec S.A. Liquid-filled chitosan-anionic liposoluble capsule dispsersions
BRPI1002601E2 (pt) * 2010-06-01 2020-06-30 Embrapa Pesquisa Agropecuaria composição nanoestruturada de uso veterinário para administração de fármacos
US20110318406A1 (en) * 2010-06-23 2011-12-29 Eley Crispin G S Lecithin carrier vesicles and methods of making the same
WO2012070031A1 (en) * 2010-11-26 2012-05-31 University Of The Witwatersrand, Johannesburg Polymeric matrix of polymer-lipid nanoparticles as a pharmaceutical dosage form
US9801829B2 (en) * 2011-04-29 2017-10-31 University Of Florida Research Foundation, Inc. Methods and systems of making nanostructures
DE102011076149A1 (de) * 2011-05-19 2012-11-22 Rovi Cosmetics International Gmbh Ladungsgeber für ein vesikuläres Trägersystem eines UV-Schutzmittels für die Haut oder die Haare
ES2366255B2 (es) * 2011-06-27 2012-08-08 Universidade De Santiago De Compostela Nanocomposiciones sacarídicas para la liberación de vacunas.
LT3095484T (lt) 2011-11-02 2018-08-10 Keybioscience Ag Kalcitonino mimetikai, skirti ligų ir sutrikimų gydymui
MX351092B (es) 2011-11-02 2017-10-02 Keybioscience Ag Analogos peptidicos para tratar enfermedades y trastornos.
KR102015151B1 (ko) * 2011-11-15 2019-08-27 알러간, 인코포레이티드 사이클로스포린 a 제2형의 고압멸균처리 가능한 현탁액
US8968790B2 (en) * 2011-12-09 2015-03-03 Shaker A. Mousa Nanoformulation of vitamin D derivatives and/or vitamin D metabolites
EP2625966A1 (en) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanoparticles comprising a vegetable hydrophobic protein and a water miscible non-volatile organic solvent and uses thereof
EP2934740B1 (en) * 2012-12-21 2019-12-11 Bracco Suisse SA Gas-filled microvesicles
CA3002989C (en) 2013-10-14 2021-03-16 Nanosphere Health Sciences, Llc Nanoparticle compositions and methods as carriers of nutraceutical factors across cell membranes and biological barriers
RS58530B1 (sr) 2013-11-14 2019-04-30 Keybioscience Ag Mimetici kalcitonina za lečenje bolesti i poremećaja
CN104117066B (zh) * 2014-07-16 2016-03-02 陈凌 外敷用抗甲状腺软膏的制备方法
CA3050535C (en) 2014-12-15 2021-11-09 Richard Clark Kaufman Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of anti-inflammatory nutraceuticals
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
CA2979184C (en) 2015-03-10 2020-09-08 Nanosphere Health Sciences, Llc Lipid nanoparticle compositions and methods as carriers of cannabinoids in standardized precision-metered dosage forms
PL229276B1 (pl) * 2015-07-17 2018-06-29 Univ Jagiellonski Nanokapsuła do przenoszenia związku lipofilowego i sposób jej wytwarzania
TWI709410B (zh) * 2015-08-11 2020-11-11 荷蘭商艾西優藥物股份有限公司 具有生物活性親脂性化合物之聚乙二醇化脂質奈米粒子
JP2019513359A (ja) * 2016-03-25 2019-05-30 アディッソ・フランス・エス．エー．エス．Ａｄｉｓｓｅｏ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． 脂溶性の有効成分のナノカプセル並びにその製造方法及び使用方法
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
CN109316602A (zh) * 2018-11-13 2019-02-12 西安力邦医药科技有限责任公司 一种长效镇痛并促进伤口愈合的复方缓释递药系统的组方与应用
AU2019398117B2 (en) 2018-12-11 2021-04-15 Disruption Labs Inc. Compositions for the delivery of therapeutic agents and methods of use and making thereof
KR102384808B1 (ko) * 2018-12-20 2022-04-08 주식회사 스킨메드 키토산으로 코팅된 나노 캡슐 및 이의 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
US5527537A (en) * 1992-05-18 1996-06-18 Dietl; Hans Pharmaceutical preparation containing cyclosporine(s) for intravenous administration and a process for its production
US20030224022A1 (en) * 1993-01-19 2003-12-04 Amos Nussinovitch Hydrocolloid cellular solid matrices
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
ES2093562B1 (es) * 1995-05-26 1997-07-01 Univ Santiago Compostela Estabilizacion de sistemas coloidales mediante formacion de complejos ionicos lipido-polisacarido.
US6649192B2 (en) * 1996-07-29 2003-11-18 Universidade De Santiago De Compostela Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms
JP3441665B2 (ja) * 1999-02-04 2003-09-02 株式会社資生堂 （２−置換オキシフェニル）アルカンアミド誘導体及び養毛剤、皮膚外用剤
EP1190702A1 (en) * 2000-09-22 2002-03-27 Ciba SC Holding AG Chitosan emulsion formulation
DE50105026D1 (de) * 2001-03-22 2005-02-10 Cognis Iberia Sl Nanokapseln
CN100335036C (zh) * 2001-11-01 2007-09-05 耶路撒冷希伯来语大学依苏姆研究开发公司 用于干眼症治疗的方法和组合物

Also Published As

Publication number Publication date
WO2007104732A2 (en) 2007-09-20
AR059829A1 (es) 2008-04-30
BRPI0709594A2 (pt) 2011-07-19
JP5222739B2 (ja) 2013-06-26
WO2007104732A3 (en) 2007-11-08
CN101426479B (zh) 2012-10-10
EP1834635A1 (en) 2007-09-19
ES2369244T3 (es) 2011-11-28
EP1834635B1 (en) 2011-07-06
PL1834635T3 (pl) 2012-01-31
AU2007224471A1 (en) 2007-09-20
US20090074824A1 (en) 2009-03-19
CA2646338A1 (en) 2007-09-20
AU2007224471B2 (en) 2013-05-02
JP2009530241A (ja) 2009-08-27
CN101426479A (zh) 2009-05-06
PT1834635E (pt) 2011-10-13
IL194005A0 (en) 2011-08-01
ATE515260T1 (de) 2011-07-15
KR20080102303A (ko) 2008-11-24
PE20080141A1 (es) 2008-03-04

Similar Documents

Publication Publication Date Title
DK1834635T3 (da) Stabile nanokapselsystemer til administrtion af aktive molekyler
DK1983964T3 (da) Anordning til indgivelse af lægemiddel
DK2959894T3 (da) S1p-receptormodulatorer til behandling af multipel sklerose
DK3851447T3 (da) Fremgangsmåder, forbindelser, sammensætninger og vehikler til administration af 3-amino-1-propansulfonsyre
DK2117521T3 (da) Transdermale indgivelsessystemer omfattende bupivacain
DK2054042T3 (da) Fremgangsmåder til fremstilling af biologisk aktive forbindelser i nanopartikelform
DK2058020T3 (da) Indretning til indgivelse af lægemiddel
DK2086944T3 (da) Fremgangsmåde til fremstilling af difluormethylpyrazolylcarboxylater
DE602005001512D1 (de) System zur intravenösen Verabreichung
DK1928438T3 (da) Anvendelse af ibudilast til behandling af stofafhængighed
DK2173407T3 (da) Anordning til indgivelse af lægemiddel
BRPI0821876A8 (pt) sistemas e métodos para administração de medicação
BRPI0821169A2 (pt) Sistema para estabilização ativa e passiva de uma embarcação, e, métodos para estabilização ativa de uma embarcação e para estabilização passiva de uma embarcação
DK2462116T3 (da) Fremgangsmåde til fremstillingen af farmaceutisk aktive forbindelser
DE602007008562D1 (de) Flüssigkeitsausgabespritze
DK2019683T4 (da) Indgivelse af vækstfaktorer til behandling af CNS-lidelser
BRPI0821474A2 (pt) formulação farmacêutica líquida estável
DK1947933T4 (da) System til styret udbringning af herbicider
DK2094676T3 (da) Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater
DK1942967T3 (da) Fremgangsmåde til dosering af medikamenter
DK2249866T3 (da) Anvendelse af et acetylsalicylsyresalt til behandlingen af virusinfektioner
DK1986622T3 (da) Små-molekyle-modulatorer af Trp-p8-aktivitet
ATE494896T1 (de) Stabile parenterale formulierung mit einem rsv- hemmer einer benzodiazepin-struktur
DK1795186T3 (da) Flupirtinomfattende lægemiddelformulering med en kontrolleret frisætning af det aktive middel
DK2251019T3 (da) Middel til forebyggelse af alkoholhepatopati