ATE515260T1 - Stabile nanokapselsysteme für die verabreichung von wirkstoffen - Google Patents

Stabile nanokapselsysteme für die verabreichung von wirkstoffen

Info

Publication number
ATE515260T1
ATE515260T1 AT06380048T AT06380048T ATE515260T1 AT E515260 T1 ATE515260 T1 AT E515260T1 AT 06380048 T AT06380048 T AT 06380048T AT 06380048 T AT06380048 T AT 06380048T AT E515260 T1 ATE515260 T1 AT E515260T1
Authority
AT
Austria
Prior art keywords
administration
active ingredients
stable
nanocapsule systems
stable nanocapsule
Prior art date
Application number
AT06380048T
Other languages
English (en)
Inventor
Pena Ana Isabel Pabellon De Servi Vila
Luque Silvia Pabellon De Servi Suarez
Fernandez M Jose Pabellon De Alonso
Original Assignee
Advanced In Vitro Cell Technologies S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced In Vitro Cell Technologies S L filed Critical Advanced In Vitro Cell Technologies S L
Application granted granted Critical
Publication of ATE515260T1 publication Critical patent/ATE515260T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/736—Chitin; Chitosan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
AT06380048T 2006-03-13 2006-03-13 Stabile nanokapselsysteme für die verabreichung von wirkstoffen ATE515260T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06380048A EP1834635B1 (de) 2006-03-13 2006-03-13 Stabile Nanokapselsysteme für die Verabreichung von Wirkstoffen

Publications (1)

Publication Number Publication Date
ATE515260T1 true ATE515260T1 (de) 2011-07-15

Family

ID=36743270

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06380048T ATE515260T1 (de) 2006-03-13 2006-03-13 Stabile nanokapselsysteme für die verabreichung von wirkstoffen

Country Status (17)

Country Link
US (1) US20090074824A1 (de)
EP (1) EP1834635B1 (de)
JP (1) JP5222739B2 (de)
KR (1) KR20080102303A (de)
CN (1) CN101426479B (de)
AR (1) AR059829A1 (de)
AT (1) ATE515260T1 (de)
AU (1) AU2007224471B2 (de)
BR (1) BRPI0709594A2 (de)
CA (1) CA2646338A1 (de)
DK (1) DK1834635T3 (de)
ES (1) ES2369244T3 (de)
IL (1) IL194005A0 (de)
PE (1) PE20080141A1 (de)
PL (1) PL1834635T3 (de)
PT (1) PT1834635E (de)
WO (1) WO2007104732A2 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007142704A2 (en) 2006-06-02 2007-12-13 Hawaii Chitopure, Inc. Chitosan-derivative compounds and methods of controlling microbial populations
US20080248508A1 (en) * 2006-08-17 2008-10-09 Shenda Baker Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials
CA2690771A1 (en) * 2007-06-12 2008-12-18 Christine Allen Injectable polymer-lipid blend for localized drug delivery
EP2042166A1 (de) * 2007-09-25 2009-04-01 The Jordanian Pharmaceutical Manufacturing Co. Nanokapseln zur oralen Verabreichung von Proteinen
US9254268B2 (en) 2007-09-25 2016-02-09 Solubest Ltd. Compositions comprising lipophilic active compounds and method for their preparation
KR101199580B1 (ko) * 2008-08-06 2013-11-27 (주)에델프라우 국소 투여용 나노에멀젼
BRPI0805854A2 (pt) 2008-10-10 2010-08-24 Biolab Sanus Farmaceutica Ltda sistema nanoparticulado, processo de preparaÇço do mesmo, uso do mesmo, composiÇço fotoproterora, processo de preparaÇço da mesma, mÉtodo de prevenÇço de doenÇas e distérbios da pele
TWI328565B (en) * 2008-12-19 2010-08-11 Taiwan Textile Res Inst Dispersions of conductive carbon materials and methods for preparing the same
CN102369018B (zh) 2009-03-12 2016-08-03 关键生物科学有限公司 糖尿病和代谢综合征的治疗
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
EP2266546A1 (de) 2009-06-08 2010-12-29 Advancell Advanced in Vitro Cell Technologies,S.A. Verfahren zur Herstellung kolloidaler Systeme zur Abgabe von Wirkstoffen
EP2364600A1 (de) * 2010-02-18 2011-09-14 Nestec S.A. Flüssigkeitsgefüllte chitosan-anionische fettlösliche Kapseldispersionen
BRPI1002601E2 (pt) * 2010-06-01 2020-06-30 Embrapa Pesquisa Agropecuaria composição nanoestruturada de uso veterinário para administração de fármacos
JP6189749B2 (ja) * 2010-06-23 2017-08-30 ブライトサイド イノベーションズ，インコーポレイティド レシチン担体小胞とその作製方法
JP2013543886A (ja) * 2010-11-26 2013-12-09 ユニバーシティ・オブ・ザ・ウィットウォータースランド・ヨハネスブルグ 医薬投与形態としてのポリマー−脂質ナノ粒子のポリマーマトリックス
US9801829B2 (en) * 2011-04-29 2017-10-31 University Of Florida Research Foundation, Inc. Methods and systems of making nanostructures
DE102011076149A1 (de) * 2011-05-19 2012-11-22 Rovi Cosmetics International Gmbh Ladungsgeber für ein vesikuläres Trägersystem eines UV-Schutzmittels für die Haut oder die Haare
ES2366255B2 (es) * 2011-06-27 2012-08-08 Universidade De Santiago De Compostela Nanocomposiciones sacarídicas para la liberación de vacunas.
HUE039105T2 (hu) 2011-11-02 2018-12-28 Keybioscience Ag Kalcitonin mimetikumok betegségek és rendellenességek kezelésére
KR102019911B1 (ko) 2011-11-02 2019-09-09 키바이오사이언스 아게 질병 및 장애 치료용 펩타이드 유사체
CA2856074C (en) * 2011-11-15 2017-07-04 Allergan, Inc. Autoclavable suspensions of cyclosporin a form 2
US8968790B2 (en) * 2011-12-09 2015-03-03 Shaker A. Mousa Nanoformulation of vitamin D derivatives and/or vitamin D metabolites
EP2625966A1 (de) 2012-02-13 2013-08-14 Bionanoplus, S.L. Nanopartikel mit einem pflanzlichen hydrophoben Protein und wassermischbare nichtflüchtige organische Lösung sowie Verwendungen davon
WO2014096165A2 (en) * 2012-12-21 2014-06-26 Bracco Suisse Sa Gas-filled microvesicles
AU2014337519A1 (en) 2013-10-14 2016-05-05 Nanosphere Health Sciences, Llc Nanoparticle compositions and methods as carriers of nutraceutical factors across cell membranes and biological barriers
MX2016006049A (es) 2013-11-14 2016-08-12 Keybioscience Ag Mimeticos de calcitonina para tratar enfermedades y trastornos.
CN104117066B (zh) 2014-07-16 2016-03-02 陈凌 外敷用抗甲状腺软膏的制备方法
US11707436B2 (en) 2014-12-15 2023-07-25 Nanosphere Health Sciences Inc. Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of NSAIDS
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
EP3268043A4 (de) 2015-03-10 2018-12-19 Nanosphere Health Sciences, LLC Lipidnanoteilchenzusammensetzungen und verfahren als träger von cannabinoiden in standardisierten präzisionsabgemessenen darreichungsformen
PL229276B1 (pl) * 2015-07-17 2018-06-29 Univ Jagiellonski Nanokapsuła do przenoszenia związku lipofilowego i sposób jej wytwarzania
EP3334416A1 (de) * 2015-08-11 2018-06-20 Eyesiu Medicines B.V. Pegyliertes lipidnanoteilchen mit bioaktiver lipophiler verbindung
WO2017162963A1 (fr) * 2016-03-25 2017-09-28 Adisseo France S.A.S. Nanocapsules de principe actif liposoluble, fabrication et utilisations
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
CN109316602A (zh) * 2018-11-13 2019-02-12 西安力邦医药科技有限责任公司 一种长效镇痛并促进伤口愈合的复方缓释递药系统的组方与应用
EP4272731A3 (de) 2018-12-11 2024-02-14 Disruption Labs Inc. Zusammensetzungen zur abgabe von therapeutika und verfahren zu deren verwendung und herstellung
KR102384808B1 (ko) * 2018-12-20 2022-04-08 주식회사 스킨메드 키토산으로 코팅된 나노 캡슐 및 이의 용도

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
DE59310166D1 (de) * 1992-05-18 2001-05-31 Ciclomulsion Ag Cyclosporin(e) enthaltende pharmazeutische Zubereitung zur intravenösen Applikation sowie Verfahren zu ihrer Herstellung
US20030224022A1 (en) * 1993-01-19 2003-12-04 Amos Nussinovitch Hydrocolloid cellular solid matrices
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery
ES2093562B1 (es) * 1995-05-26 1997-07-01 Univ Santiago Compostela Estabilizacion de sistemas coloidales mediante formacion de complejos ionicos lipido-polisacarido.
US6649192B2 (en) * 1996-07-29 2003-11-18 Universidade De Santiago De Compostela Application of nanoparticles based on hydrophilic polymers as pharmaceutical forms
JP3441665B2 (ja) * 1999-02-04 2003-09-02 株式会社資生堂 （２−置換オキシフェニル）アルカンアミド誘導体及び養毛剤、皮膚外用剤
EP1190702A1 (de) * 2000-09-22 2002-03-27 Ciba SC Holding AG Emulgierte Chitosan Zusammensetzung
EP1243323B1 (de) * 2001-03-22 2005-01-05 Cognis Iberia, S.L. Nanokapseln
JP2005513097A (ja) * 2001-11-01 2005-05-12 イサム・リサーチ・デベロツプメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシテイ・オブ・エルサレム ドライアイ治療方法および組成物

Also Published As

Publication number Publication date
AU2007224471B2 (en) 2013-05-02
AR059829A1 (es) 2008-04-30
AU2007224471A1 (en) 2007-09-20
US20090074824A1 (en) 2009-03-19
CN101426479B (zh) 2012-10-10
CA2646338A1 (en) 2007-09-20
CN101426479A (zh) 2009-05-06
JP2009530241A (ja) 2009-08-27
JP5222739B2 (ja) 2013-06-26
IL194005A0 (en) 2011-08-01
BRPI0709594A2 (pt) 2011-07-19
KR20080102303A (ko) 2008-11-24
PE20080141A1 (es) 2008-03-04
ES2369244T3 (es) 2011-11-28
PL1834635T3 (pl) 2012-01-31
EP1834635B1 (de) 2011-07-06
WO2007104732A2 (en) 2007-09-20
WO2007104732A3 (en) 2007-11-08
DK1834635T3 (da) 2011-10-24
EP1834635A1 (de) 2007-09-19
PT1834635E (pt) 2011-10-13

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