DK2094676T3 - Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater - Google Patents
Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivaterInfo
- Publication number
- DK2094676T3 DK2094676T3 DK07849225.3T DK07849225T DK2094676T3 DK 2094676 T3 DK2094676 T3 DK 2094676T3 DK 07849225 T DK07849225 T DK 07849225T DK 2094676 T3 DK2094676 T3 DK 2094676T3
- Authority
- DK
- Denmark
- Prior art keywords
- iminothiazolidin
- derivatives
- preparation
- new procedure
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IB2006054409 | 2006-11-23 | ||
PCT/IB2007/054752 WO2008062376A2 (en) | 2006-11-23 | 2007-11-22 | New process for the preparation of 2-imino-thiazolidin-4-one derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2094676T3 true DK2094676T3 (da) | 2013-06-10 |
Family
ID=39316391
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12000613.5T DK2489662T3 (da) | 2006-11-23 | 2007-11-22 | Mellemprodukter af en ny fremgangsmåde til fremstillingen af 5-benzyliden-2-alkylimino-3-phenylthiazolidin-4-on derivater |
DK07849225.3T DK2094676T3 (da) | 2006-11-23 | 2007-11-22 | Ny fremgangsmåde til fremstillingen af 2-iminothiazolidin-4-on-derivater |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12000613.5T DK2489662T3 (da) | 2006-11-23 | 2007-11-22 | Mellemprodukter af en ny fremgangsmåde til fremstillingen af 5-benzyliden-2-alkylimino-3-phenylthiazolidin-4-on derivater |
Country Status (14)
Country | Link |
---|---|
US (1) | US8263780B2 (da) |
EP (2) | EP2094676B1 (da) |
JP (1) | JP4669564B2 (da) |
KR (1) | KR101255879B1 (da) |
CN (2) | CN101541772B (da) |
AU (1) | AU2007323042B2 (da) |
BR (1) | BRPI0718986A2 (da) |
CA (1) | CA2669069C (da) |
DK (2) | DK2489662T3 (da) |
ES (2) | ES2523401T3 (da) |
IL (1) | IL198847A (da) |
MX (1) | MX2009005048A (da) |
TW (1) | TWI460166B (da) |
WO (1) | WO2008062376A2 (da) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE43833E1 (en) | 2003-11-21 | 2012-11-27 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
ES2352555T3 (es) | 2003-11-21 | 2011-02-21 | Actelion Pharmaceuticals Ltd. | Derivados de 5-(benc-(z)-iliden)tiazolidin-4-ona como agentes inmunosupresores. |
US8912340B2 (en) | 2006-11-23 | 2014-12-16 | Actelion Pharmaceuticals Ltd. | Process for the preparation of 2-imino-thiazolidin-4-one derivatives |
AR070842A1 (es) * | 2008-03-17 | 2010-05-05 | Actelion Pharmaceuticals Ltd | Regimen de dosificacion para un agonista de receptor selectivo de s1p1 |
GB0819182D0 (en) | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
EP2885266B1 (en) | 2012-08-17 | 2020-03-18 | Actelion Pharmaceuticals Ltd | Process for the preparation of (2z,5z)-5-(3-chloro-4-((r)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one and intermediate used in said process |
UA122064C2 (uk) | 2014-12-11 | 2020-09-10 | Актеліон Фармасьютікалз Лтд | Схема дозування для селективного агоніста рецептора s1p1 |
MA41139A (fr) | 2014-12-11 | 2017-10-17 | Actelion Pharmaceuticals Ltd | Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1 |
JOP20190207A1 (ar) | 2017-03-14 | 2019-09-10 | Actelion Pharmaceuticals Ltd | تركيبة صيدلانية تشتمل على بونيسيمود |
US11220488B2 (en) | 2017-09-19 | 2022-01-11 | Teva Pharmaceuticals International Gmbh | Crystalline polymorph of Ponesimod |
US11014940B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Thiazolidinone and oxazolidinone compounds and formulations |
US11013723B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms of a thiazolidinone compound, compositions and methods of use thereof |
US11186556B1 (en) | 2018-10-16 | 2021-11-30 | Celgene Corporation | Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof |
US11014897B1 (en) | 2018-10-16 | 2021-05-25 | Celgene Corporation | Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof |
EP3997076A1 (de) * | 2019-07-10 | 2022-05-18 | Bayer Aktiengesellschaft | Verfahren zur herstellung von 2-(phenylimino)-1,3-thiazolidin-4-onen |
JP2022540114A (ja) * | 2019-07-10 | 2022-09-14 | バイエル・アクチエンゲゼルシヤフト | 2-(フェニルイミノ)-1,3-チアゾリジン-4-オン類の調製方法 |
EP4051250A1 (en) | 2019-10-31 | 2022-09-07 | Idorsia Pharmaceuticals Ltd | Combination of a cxcr7 antagonist with an s1p1 receptor modulator |
KR20200019639A (ko) | 2020-01-30 | 2020-02-24 | 전대연 | 만남의 스마트 도착시스템 |
KR20220143032A (ko) * | 2020-02-18 | 2022-10-24 | 바이엘 악티엔게젤샤프트 | 2-(페닐이미노)-3-알킬-1,3-티아졸리딘-4-온의 제조 방법 |
WO2023022896A1 (en) | 2021-08-17 | 2023-02-23 | Teva Czech Industries S.R.O | Polymorphs of ponesimod |
EP4212156A1 (en) | 2022-01-13 | 2023-07-19 | Abivax | Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator |
WO2023152691A1 (en) * | 2022-02-10 | 2023-08-17 | Metrochem Api Pvt Ltd | Process for the preparation of ponesimod and its intermediates thereof |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3077402A (en) * | 1954-12-06 | 1963-02-12 | Polaroid Corp | Photographic color processes, products, and compositions |
NL270002A (da) * | 1960-10-08 | |||
OA03835A (fr) * | 1970-07-17 | 1971-12-24 | Rhone Poulenc Sa | Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent. |
PT97507B (pt) * | 1990-04-27 | 1998-08-31 | Orion Yhtymae Oy | Processo para apreparacao de novos derivados de catecol farmacologicamente activos |
TW221689B (da) * | 1991-08-27 | 1994-03-11 | Otsuka Pharma Co Ltd | |
KR100250701B1 (ko) * | 1993-02-26 | 2000-07-01 | 오쓰까 아끼히꼬 | 메일라드 반응 억제제로서의 티아졸 또는 이미다졸 유도체 |
KR960022486A (ko) | 1994-12-29 | 1996-07-18 | 김준웅 | 신규 티아졸리딘-4-온 유도체 |
US6353006B1 (en) * | 1999-01-14 | 2002-03-05 | Bayer Corporation | Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents |
WO2001019807A1 (fr) | 1999-09-14 | 2001-03-22 | Shionogi & Co., Ltd. | Derives de 2-imino-1,3-thiazine |
ATE345332T1 (de) * | 1999-11-12 | 2006-12-15 | Fujimoto Brothers Co Ltd | 2-(n-cyanimino)thiazolidin-4-on derivate |
US20050019825A9 (en) * | 2002-03-15 | 2005-01-27 | Qing Dong | Common ligand mimics: pseudothiohydantoins |
JP4782564B2 (ja) | 2002-07-10 | 2011-09-28 | メルク セローノ ソシエテ アノニム | アゾリジノン−ビニル縮合−ベンゼン誘導体 |
GB0217152D0 (en) | 2002-07-24 | 2002-09-04 | Novartis Ag | Organic compounds |
US7767701B2 (en) * | 2002-11-22 | 2010-08-03 | Glaxosmithkline Llc | Chemical compounds |
US20040167192A1 (en) * | 2003-01-16 | 2004-08-26 | David Solow-Cordero | Methods of treating conditions associated with an Edg-7 receptor |
ES2352555T3 (es) * | 2003-11-21 | 2011-02-21 | Actelion Pharmaceuticals Ltd. | Derivados de 5-(benc-(z)-iliden)tiazolidin-4-ona como agentes inmunosupresores. |
US20070249599A1 (en) * | 2004-02-25 | 2007-10-25 | Duffy Kevin J | Novel Chemical Compounds |
WO2006094233A1 (en) * | 2005-03-03 | 2006-09-08 | Sirtris Pharmaceuticals, Inc. | N,n'-dicyclic isothiourea sirtuin modulators |
AR070842A1 (es) * | 2008-03-17 | 2010-05-05 | Actelion Pharmaceuticals Ltd | Regimen de dosificacion para un agonista de receptor selectivo de s1p1 |
GB0819182D0 (en) * | 2008-10-20 | 2008-11-26 | Actelion Pharmaceuticals Ltd | Crystalline forms |
-
2007
- 2007-11-22 AU AU2007323042A patent/AU2007323042B2/en active Active
- 2007-11-22 KR KR1020097011745A patent/KR101255879B1/ko active IP Right Grant
- 2007-11-22 ES ES12000613.5T patent/ES2523401T3/es active Active
- 2007-11-22 MX MX2009005048A patent/MX2009005048A/es active IP Right Grant
- 2007-11-22 BR BRPI0718986-9A patent/BRPI0718986A2/pt not_active Application Discontinuation
- 2007-11-22 DK DK12000613.5T patent/DK2489662T3/da active
- 2007-11-22 JP JP2009537744A patent/JP4669564B2/ja active Active
- 2007-11-22 EP EP07849225.3A patent/EP2094676B1/en active Active
- 2007-11-22 EP EP12000613.5A patent/EP2489662B1/en active Active
- 2007-11-22 DK DK07849225.3T patent/DK2094676T3/da active
- 2007-11-22 CN CN2007800431941A patent/CN101541772B/zh active Active
- 2007-11-22 CN CN2012105461683A patent/CN103087004A/zh active Pending
- 2007-11-22 TW TW096144311A patent/TWI460166B/zh active
- 2007-11-22 WO PCT/IB2007/054752 patent/WO2008062376A2/en active Application Filing
- 2007-11-22 US US12/516,055 patent/US8263780B2/en active Active
- 2007-11-22 ES ES07849225T patent/ES2410793T3/es active Active
- 2007-11-22 CA CA2669069A patent/CA2669069C/en active Active
-
2009
- 2009-05-20 IL IL198847A patent/IL198847A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR101255879B1 (ko) | 2013-04-17 |
EP2094676B1 (en) | 2013-04-10 |
BRPI0718986A2 (pt) | 2014-02-11 |
DK2489662T3 (da) | 2014-10-20 |
CA2669069C (en) | 2015-02-17 |
ES2410793T3 (es) | 2013-07-03 |
IL198847A0 (en) | 2010-02-17 |
CA2669069A1 (en) | 2008-05-29 |
US20110201821A2 (en) | 2011-08-18 |
JP2010510976A (ja) | 2010-04-08 |
WO2008062376A2 (en) | 2008-05-29 |
WO2008062376A3 (en) | 2008-07-10 |
CN103087004A (zh) | 2013-05-08 |
AU2007323042A1 (en) | 2008-05-29 |
US20100317867A1 (en) | 2010-12-16 |
EP2094676A2 (en) | 2009-09-02 |
US8263780B2 (en) | 2012-09-11 |
CN101541772A (zh) | 2009-09-23 |
TWI460166B (zh) | 2014-11-11 |
AU2007323042B2 (en) | 2012-12-20 |
JP4669564B2 (ja) | 2011-04-13 |
TW200831474A (en) | 2008-08-01 |
EP2489662B1 (en) | 2014-08-06 |
IL198847A (en) | 2015-07-30 |
ES2523401T3 (es) | 2014-11-25 |
EP2489662A1 (en) | 2012-08-22 |
CN101541772B (zh) | 2013-04-17 |
KR20090081009A (ko) | 2009-07-27 |
MX2009005048A (es) | 2009-05-25 |
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