MX2009005048A - Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. - Google Patents

Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.

Info

Publication number
MX2009005048A
MX2009005048A MX2009005048A MX2009005048A MX2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A MX 2009005048 A MX2009005048 A MX 2009005048A
Authority
MX
Mexico
Prior art keywords
thiazolidin
derivatives
preparation
imino
new process
Prior art date
Application number
MX2009005048A
Other languages
English (en)
Inventor
Martin Bolli
Stefan Abele
Gunther Schmidt
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of MX2009005048A publication Critical patent/MX2009005048A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La presente invención se refiere a un nuevo proceso para la preparación de compuestos de 2-imino-tiazolidin-4-ona de la fórmula (I) y (II) y a los compuestos de la fórmula (II) como tales. Los presentes compuestos de la fórmula (II) pueden ser utilizados como compuestos intermedios en la preparación de los derivados de tiazolidin-4-ona de la fórmula general (II), los derivados son descritos en WO 2005/054215. Estos compuestos de la fórmula general (II) son descritos en WO 2005/054215 para que actúen como agentes inmunosupresores.
MX2009005048A 2006-11-23 2007-11-22 Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona. MX2009005048A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2006054409 2006-11-23
PCT/IB2007/054752 WO2008062376A2 (en) 2006-11-23 2007-11-22 New process for the preparation of 2-imino-thiazolidin-4-one derivatives

Publications (1)

Publication Number Publication Date
MX2009005048A true MX2009005048A (es) 2009-05-25

Family

ID=39316391

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009005048A MX2009005048A (es) 2006-11-23 2007-11-22 Nuevo proceso para la preparacion de derivados de 2-imino-tiazolidin-4-ona.

Country Status (14)

Country Link
US (1) US8263780B2 (es)
EP (2) EP2094676B1 (es)
JP (1) JP4669564B2 (es)
KR (1) KR101255879B1 (es)
CN (2) CN101541772B (es)
AU (1) AU2007323042B2 (es)
BR (1) BRPI0718986A2 (es)
CA (1) CA2669069C (es)
DK (2) DK2094676T3 (es)
ES (2) ES2523401T3 (es)
IL (1) IL198847A (es)
MX (1) MX2009005048A (es)
TW (1) TWI460166B (es)
WO (1) WO2008062376A2 (es)

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USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
ES2352555T3 (es) 2003-11-21 2011-02-21 Actelion Pharmaceuticals Ltd. Derivados de 5-(benc-(z)-iliden)tiazolidin-4-ona como agentes inmunosupresores.
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
ES2617628T5 (es) * 2008-03-17 2020-06-01 Actelion Pharmaceuticals Ltd Régimen de dosificación para un agonista selectivo del receptor de S1P1
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms
JP6322630B2 (ja) 2012-08-17 2018-05-09 アクテリオン ファーマシューティカルズ リミテッドＡｃｔｅｌｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ （２Ｚ，５Ｚ）−５−（３−クロロ−４−（（Ｒ）−２，３−ジヒドロキシプロポキシ）ベンジリデン）−２−（プロピルイミノ）−３−（ｏ−トリル）チアゾリジン−４−オンの製造方法及び前記方法において使用される中間体
MY188764A (en) 2014-12-11 2021-12-30 Actelion Pharmaceuticals Ltd Dosing regimen for a selective s1p1 receptor agonist
MA41139A (fr) 2014-12-11 2017-10-17 Actelion Pharmaceuticals Ltd Combinaison pharmaceutique comportant un agoniste sélectif du récepteur sip1
JOP20190207A1 (ar) 2017-03-14 2019-09-10 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على بونيسيمود
US11220488B2 (en) 2017-09-19 2022-01-11 Teva Pharmaceuticals International Gmbh Crystalline polymorph of Ponesimod
US11014940B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Thiazolidinone and oxazolidinone compounds and formulations
US11013723B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms of a thiazolidinone compound, compositions and methods of use thereof
US11186556B1 (en) 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
US11014897B1 (en) 2018-10-16 2021-05-25 Celgene Corporation Solid forms comprising a thiazolidinone compound, compositions and methods of use thereof
JP2022540115A (ja) * 2019-07-10 2022-09-14 バイエル・アクチエンゲゼルシヤフト ２－（フェニルイミノ）－１，３－チアゾリジン－４－オン類の調製方法
CN114040910A (zh) * 2019-07-10 2022-02-11 拜耳公司 制备2-(苯基亚氨基)-1,3-噻唑烷-4-酮的方法
AU2020372647A1 (en) 2019-10-31 2022-06-16 Idorsia Pharmaceuticals Ltd Combination of a CXCR7 antagonist with an S1P1 receptor modulator
KR20200019639A (ko) 2020-01-30 2020-02-24 전대연 만남의 스마트 도착시스템
KR20220143032A (ko) * 2020-02-18 2022-10-24 바이엘 악티엔게젤샤프트 2-(페닐이미노)-3-알킬-1,3-티아졸리딘-4-온의 제조 방법
WO2023022896A1 (en) 2021-08-17 2023-02-23 Teva Czech Industries S.R.O Polymorphs of ponesimod
EP4212156A1 (en) 2022-01-13 2023-07-19 Abivax Combination of 8-chloro-n-(4-(trifluoromethoxy)phenyl)quinolin-2-amine and its derivatives with a s1p receptor modulator
WO2023152691A1 (en) * 2022-02-10 2023-08-17 Metrochem Api Pvt Ltd Process for the preparation of ponesimod and its intermediates thereof

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US3077402A (en) * 1954-12-06 1963-02-12 Polaroid Corp Photographic color processes, products, and compositions
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OA03835A (fr) * 1970-07-17 1971-12-24 Rhone Poulenc Sa Nouveaux dérivés de la thiazolidine, leur préparation et les compositions qui les contiennent.
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CN1037842C (zh) * 1993-02-26 1998-03-25 大制药株式会社 取代的噻唑烷衍生物及其药物组合物和用途
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US6353006B1 (en) * 1999-01-14 2002-03-05 Bayer Corporation Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents
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ES2617628T5 (es) * 2008-03-17 2020-06-01 Actelion Pharmaceuticals Ltd Régimen de dosificación para un agonista selectivo del receptor de S1P1
GB0819182D0 (en) * 2008-10-20 2008-11-26 Actelion Pharmaceuticals Ltd Crystalline forms

Also Published As

Publication number Publication date
WO2008062376A3 (en) 2008-07-10
US20100317867A1 (en) 2010-12-16
CN101541772B (zh) 2013-04-17
JP2010510976A (ja) 2010-04-08
CA2669069A1 (en) 2008-05-29
CN103087004A (zh) 2013-05-08
AU2007323042A1 (en) 2008-05-29
US8263780B2 (en) 2012-09-11
IL198847A0 (en) 2010-02-17
CN101541772A (zh) 2009-09-23
IL198847A (en) 2015-07-30
TWI460166B (zh) 2014-11-11
EP2489662A1 (en) 2012-08-22
AU2007323042B2 (en) 2012-12-20
US20110201821A2 (en) 2011-08-18
ES2410793T3 (es) 2013-07-03
WO2008062376A2 (en) 2008-05-29
BRPI0718986A2 (pt) 2014-02-11
ES2523401T3 (es) 2014-11-25
KR101255879B1 (ko) 2013-04-17
JP4669564B2 (ja) 2011-04-13
TW200831474A (en) 2008-08-01
KR20090081009A (ko) 2009-07-27
EP2094676B1 (en) 2013-04-10
EP2094676A2 (en) 2009-09-02
CA2669069C (en) 2015-02-17
DK2094676T3 (da) 2013-06-10
EP2489662B1 (en) 2014-08-06
DK2489662T3 (da) 2014-10-20

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