MX351092B - Analogos peptidicos para tratar enfermedades y trastornos. - Google Patents

Analogos peptidicos para tratar enfermedades y trastornos.

Info

Publication number
MX351092B
MX351092B MX2014005265A MX2014005265A MX351092B MX 351092 B MX351092 B MX 351092B MX 2014005265 A MX2014005265 A MX 2014005265A MX 2014005265 A MX2014005265 A MX 2014005265A MX 351092 B MX351092 B MX 351092B
Authority
MX
Mexico
Prior art keywords
seq
reducing
disorders
treating diseases
peptide analogs
Prior art date
Application number
MX2014005265A
Other languages
English (en)
Other versions
MX2014005265A (es
Inventor
M Mehta Nozer
Stern William
M Sturmer Amy
Asser Karsdal Morten
Henriksen Kim
Original Assignee
Keybioscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Keybioscience Ag filed Critical Keybioscience Ag
Publication of MX2014005265A publication Critical patent/MX2014005265A/es
Publication of MX351092B publication Critical patent/MX351092B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a un péptido caracterizado porque se selecciona del grupo que consiste en: SEQ. ID NO.: 15.
MX2014005265A 2011-11-02 2012-11-02 Analogos peptidicos para tratar enfermedades y trastornos. MX351092B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161554771P 2011-11-02 2011-11-02
US201161578620P 2011-12-21 2011-12-21
US13/667,578 US9006172B2 (en) 2011-11-02 2012-11-02 Peptide analogs for treating diseases and disorders
PCT/US2012/063332 WO2013067357A1 (en) 2011-11-02 2012-11-02 Peptide analogs for treating diseases and disorders

Publications (2)

Publication Number Publication Date
MX2014005265A MX2014005265A (es) 2014-10-13
MX351092B true MX351092B (es) 2017-10-02

Family

ID=48192827

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014005265A MX351092B (es) 2011-11-02 2012-11-02 Analogos peptidicos para tratar enfermedades y trastornos.

Country Status (10)

Country Link
US (1) US9006172B2 (es)
JP (3) JP6170933B2 (es)
KR (1) KR102019911B1 (es)
CN (1) CN103998052B (es)
AU (2) AU2012332265B2 (es)
BR (1) BR112014010701A2 (es)
CA (1) CA2854175A1 (es)
MX (1) MX351092B (es)
RU (1) RU2616511C2 (es)
WO (1) WO2013067357A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9533022B2 (en) * 2011-11-02 2017-01-03 KeyBioscience A/S Peptide analogs for treating diseases and disorders
PL3321278T3 (pl) 2013-11-14 2019-06-28 Keybioscience Ag Mimetyki kalcytoniny do leczenia chorób i zaburzeń
GB201500263D0 (en) 2015-01-08 2015-02-25 Keybioscience Ag Calcitonin analogues for treating diseases and disorders
GB201704429D0 (en) 2017-03-21 2017-05-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
GB201707955D0 (en) 2017-05-18 2017-07-05 Keybioscience Ag Dual amylin and calcitonin receptor agonists for treating diseases and disorders
GB201813678D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Acylated calcitonin mimetics
GB201813677D0 (en) 2018-08-22 2018-10-03 Keybioscience Ag Calcitonin mimetics for treating diseases and disorders
US11420525B2 (en) 2020-04-21 2022-08-23 Mac LTT, Inc. Tractor trailer with included battery charging
US11634095B2 (en) 2020-04-21 2023-04-25 Mac LTT, Inc. Removable safety bar for creating a remote safety visual device

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6033478B2 (ja) * 1980-06-20 1985-08-02 帝国臓器製薬株式会社 ペプチドの製造方法
US6319685B1 (en) 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
US4708934A (en) 1984-09-27 1987-11-24 Unigene Laboratories, Inc. α-amidation enzyme
US4659804A (en) * 1984-11-01 1987-04-21 Armour Pharmaceutical Company (Bis-1,7-S-acetamidomethyl-L-cysteine)salmon calcitonin
US4764589A (en) 1987-05-26 1988-08-16 Rorer Pharmaceutical Corporation [N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin
US5789234A (en) 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
US5175146A (en) 1989-12-05 1992-12-29 Vical, Inc. Synthetic calcitonin peptides
US5102666A (en) 1990-09-11 1992-04-07 Oramed, Inc. Calcium polycarbophil controlled release composition and method
US5527790A (en) 1991-09-30 1996-06-18 The University Of British Columbia Bis(maltolato)oxovanadium compositions for the treatment of elevated blood sugar
US5359030A (en) 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
US6692766B1 (en) 1994-06-15 2004-02-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Controlled release oral drug delivery system
JPH083196A (ja) 1994-06-21 1996-01-09 Sanwa Kagaku Kenkyusho Co Ltd カルシトニン誘導体及びその用途
EP0726075A1 (en) 1995-02-08 1996-08-14 Therapicon Srl Pharmaceutical non-inorganic saline solutions for endonasal administration
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5739106A (en) 1995-06-07 1998-04-14 Rink; Timothy J. Appetite regulating compositions
USRE39088E1 (en) 1995-08-22 2006-05-02 Japan Tobacco, Inc. Amide compounds and use of the same
US5962270A (en) * 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US5912014A (en) 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
US5773647A (en) 1997-02-07 1998-06-30 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
ATE522598T1 (de) 1997-04-16 2011-09-15 Unigene Lab Inc Direkte expression von peptiden in nährmedien
CN1105726C (zh) * 1998-05-15 2003-04-16 中国科学院上海生物化学研究所 人降钙素类似物
CN1329502A (zh) 1998-12-04 2002-01-02 普罗瓦利斯英国有限公司 含有胰岛素的药物组合物
JP2000290295A (ja) 1999-03-31 2000-10-17 Asahi Chem Ind Co Ltd Ｎ−アセチルグルコサミニルカルシトニン
ES2235854T3 (es) * 1999-04-05 2005-07-16 Emisphere Technologies, Inc. Sales disodicas, monohidratos y solvatos etanolicos para aportar agentes activos.
US6780846B1 (en) 1999-09-27 2004-08-24 Elan Corporation, Plc Membrane translocating peptide drug delivery system
GB2368792A (en) 2000-10-06 2002-05-15 Roger Randal Charles New Absorption enhancers
US6673574B2 (en) 2000-11-30 2004-01-06 Unigene Laboratories Inc. Oral delivery of peptides using enzyme-cleavable membrane translocators
US7316819B2 (en) 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
GB0109438D0 (en) * 2001-04-17 2001-06-06 Isis Innovation Peptides
US6770625B2 (en) 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
ES2665464T3 (es) 2003-03-28 2018-04-25 Sigmoid Pharma Limited Forma de dosificación oral sólida que contiene microcápsulas sin costuras
GB0308732D0 (en) 2003-04-15 2003-05-21 Axcess Ltd Absorption enhancers
AU2004262906B2 (en) 2003-07-23 2008-04-03 Nordic Bioscience A/S Use of calcitonin in osteoarthritis
JP2007523050A (ja) 2003-09-17 2007-08-16 カイアズマ・リミテッド 生物学的障壁を通した透過を容易にすることのできる組成物
RU2385878C2 (ru) 2004-02-11 2010-04-10 Амилин Фармасьютикалз, Инк. Пептид, обладающий свойствами амилина (варианты), и его применение (варианты)
US7399744B2 (en) 2004-03-04 2008-07-15 Amylin Pharmaceuticals, Inc. Methods for affecting body composition
AU2005263729B2 (en) 2004-07-22 2011-01-06 Bey Pharma GmbH Use of compounds containing thiol groups as an efflux pump inhibitor
GB0422644D0 (en) 2004-10-12 2004-11-10 Novartis Ag Organic compounds
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
US7445911B2 (en) 2004-11-24 2008-11-04 Unigene Laboratories Inc. Enzymatic reactions in the presence of keto acids
JP4856177B2 (ja) 2005-06-24 2012-01-18 ユニジーン・ラボラトリーズ・インコーポレーテッド アミド化生成物の調製に有用な酵素を発現させるための細胞株
ES2462117T3 (es) 2005-09-06 2014-05-22 Oramed Pharmaceuticals Inc. Métodos y composiciones para la administración oral de proteínas
US8093207B2 (en) 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
ATE515260T1 (de) 2006-03-13 2011-07-15 Advanced In Vitro Cell Technologies S L Stabile nanokapselsysteme für die verabreichung von wirkstoffen
BRPI0710503A2 (pt) 2006-04-07 2011-08-16 Merrion Res Iii Ltd uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral
US8377863B2 (en) 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
US8962015B2 (en) 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
CA2750035C (en) 2009-01-22 2018-02-27 Unigene Laboratories Inc. Treatment for obesity
EP2762150A1 (en) * 2009-03-12 2014-08-06 Nordic Bioscience A/S Treatment of Diabetes and Metabolic Syndrome

Also Published As

Publication number Publication date
CN103998052B (zh) 2016-08-17
RU2616511C2 (ru) 2017-04-17
JP2014532722A (ja) 2014-12-08
AU2016247189B2 (en) 2017-09-14
JP2018135360A (ja) 2018-08-30
US20130183385A1 (en) 2013-07-18
MX2014005265A (es) 2014-10-13
BR112014010701A2 (pt) 2020-06-23
CA2854175A1 (en) 2013-05-10
AU2016247189A1 (en) 2016-11-10
WO2013067357A1 (en) 2013-05-10
CN103998052A (zh) 2014-08-20
NZ625215A (en) 2016-04-29
US9006172B2 (en) 2015-04-14
RU2014122171A (ru) 2015-12-10
KR102019911B1 (ko) 2019-09-09
AU2012332265B2 (en) 2016-11-10
KR20140093967A (ko) 2014-07-29
JP6330013B2 (ja) 2018-05-23
AU2012332265A1 (en) 2014-06-05
JP6170933B2 (ja) 2017-07-26
JP6547034B2 (ja) 2019-07-17
JP2017061500A (ja) 2017-03-30

Similar Documents

Publication Publication Date Title
MX351092B (es) Analogos peptidicos para tratar enfermedades y trastornos.
PH12018500767A1 (en) Pharmaceutical composition, methods for treating and uses thereof
MY176863A (en) Ibat inhibitors for treatment of metabolic disorders and related conditions
MX2014015423A (es) Analogos de peptido de exedina-4.
MX347324B (es) Uso de dosis bajas de il-2 para tratar trastornos inflamatorios o relacionados con la autoinmunidad.
PH12015501116A1 (en) New indanyloxydihydrobenzofuranylacetic acids
MY173828A (en) A composition for treating diabetes or diabesity comprising oxyntomodulin analog
EA201101524A1 (ru) Способ и композиция для лечения состояния, связанного с хемосенсорным рецептором
BR112014006587A2 (pt) modulação antisense da expressão de gcgr
PH12015502102B1 (en) Reducing proinflammatory response
WO2015063081A3 (en) Micrornas modulating the effect of glucocorticoid signaling
NZ595021A (en) Treatment of diabetes and metabolic syndrome with enteral formulations of calcitonin peptides or calcitonin receptor agonists
BR112013018782A2 (pt) compostos e seus efeitos no comportamento alimentar
PH12016500705A1 (en) Calcitonin mimetics for treating diseases and disorders
EP2579876A4 (en) THERAPEUTIC TREATMENT OF METABOLIC SYNDROME, TYPE 2 DIABETES, OBESITY OR PREDICT
WO2014036528A3 (en) Agents useful for treating obesity, diabetes and related disorders
WO2013003449A3 (en) Methods of treatment with glp-1 receptor agonists
EP2646032A4 (en) THERAPEUTIC TREATMENT OF METABOLIC SYNDROME AND TYPE 2 DIABETES, ADIPOSITAS OR PREDICTES
WO2012109561A3 (en) Tripeptide compositions and methods for treatment of diabetes
PH12014502802A1 (en) Novel compound having ability to inhibit 11b-hsd1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient
AU2010353685A8 (en) Novel glucagon like peptide analogs, composition, and method of use
PH12015502100A1 (en) Reducing the risk of autoimmune disease
WO2013006692A3 (en) Methods of treatment using a pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1)
MX2014003883A (es) Inhibidores de monoacilglicerol lipasa para el tratamiento de enfermedades metabolicas y transtornos relacionados.
CY1120332T1 (el) Μιμητικα καλσιτονινης για τη θεραπεια των ασθενειων και των διαταραχων

Legal Events

Date Code Title Description
FG Grant or registration