OA07419A - Activateur de plamimogène de tissu humain, son procédé de production et composition pharmaceutique le contenant. - Google Patents

Activateur de plamimogène de tissu humain, son procédé de production et composition pharmaceutique le contenant.

Info

Publication number
OA07419A
OA07419A OA57990A OA57990A OA07419A OA 07419 A OA07419 A OA 07419A OA 57990 A OA57990 A OA 57990A OA 57990 A OA57990 A OA 57990A OA 07419 A OA07419 A OA 07419A
Authority
OA
OAPI
Prior art keywords
plamimogen
activator
pharmaceutical composition
composition containing
production process
Prior art date
Application number
OA57990A
Other languages
English (en)
French (fr)
Inventor
David Van Norman Goeddel
William Jack Kohr
Diane Bennica
Gordon Allen Vehar
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27409206&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=OA07419(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/483,052 external-priority patent/US4766075A/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of OA07419A publication Critical patent/OA07419A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • C12N9/003—Dihydrofolate reductase [DHFR] (1.5.1.3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
OA57990A 1982-05-05 1983-05-05 Activateur de plamimogène de tissu humain, son procédé de production et composition pharmaceutique le contenant. OA07419A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37486082A 1982-05-05 1982-05-05
US39800382A 1982-07-14 1982-07-14
US06/483,052 US4766075A (en) 1982-07-14 1983-04-07 Human tissue plasminogen activator

Publications (1)

Publication Number Publication Date
OA07419A true OA07419A (fr) 1984-11-30

Family

ID=27409206

Family Applications (1)

Application Number Title Priority Date Filing Date
OA57990A OA07419A (fr) 1982-05-05 1983-05-05 Activateur de plamimogène de tissu humain, son procédé de production et composition pharmaceutique le contenant.

Country Status (26)

Country Link
EP (1) EP0093619B2 (bg)
JP (2) JPH0216981A (bg)
AR (1) AR241654A1 (bg)
BG (1) BG60253B1 (bg)
BR (1) BR8302318A (bg)
CA (1) CA1293211C (bg)
CS (1) CS248705B2 (bg)
CY (1) CY1341A (bg)
DD (1) DD210303A5 (bg)
DE (3) DE93619T1 (bg)
DK (1) DK174236B1 (bg)
ES (1) ES522085A0 (bg)
FR (1) FR2526443B1 (bg)
GB (1) GB2119804B (bg)
GR (1) GR79202B (bg)
HK (1) HK88586A (bg)
IE (1) IE54975B1 (bg)
IL (1) IL68561A (bg)
KE (1) KE3647A (bg)
MY (1) MY8700119A (bg)
NO (2) NO831575L (bg)
OA (1) OA07419A (bg)
PL (1) PL152438B1 (bg)
PT (1) PT76636B (bg)
RO (1) RO90639B (bg)
ZW (1) ZW10483A1 (bg)

Families Citing this family (106)

* Cited by examiner, † Cited by third party
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US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
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JPS5852634B2 (ja) * 1980-12-05 1983-11-24 株式会社林原生物化学研究所 ウロキナ−ゼの製造法
GR79202B (bg) * 1982-05-05 1984-10-22 Genentech Inc
KR840004781A (ko) * 1982-05-05 1984-10-24 월터 에이치·드레거 인체의 조직 플라스미노겐 활성화제

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ZW10483A1 (en) 1983-09-21
BG60253B2 (bg) 1994-03-24
DE3316297C2 (bg) 1989-09-21
EP0093619B2 (en) 1996-09-18
FR2526443A1 (fr) 1983-11-10
IL68561A (en) 1991-01-31
BR8302318A (pt) 1984-01-10
HK88586A (en) 1986-11-28
PT76636B (en) 1986-01-10
DE93619T1 (de) 1987-08-13
KE3647A (en) 1986-07-25
PL152438B1 (en) 1990-12-31
NO831575L (no) 1983-11-07
PL241805A1 (en) 1984-07-30
GB8312221D0 (en) 1983-06-08
DK198883D0 (da) 1983-05-04
PT76636A (en) 1983-06-01
ES8501629A1 (es) 1984-12-16
AR241654A1 (es) 1992-10-30
DK198883A (da) 1983-12-20
JP2564444B2 (ja) 1996-12-18
MY8700119A (en) 1987-12-31
IE54975B1 (en) 1990-04-11
GR79202B (bg) 1984-10-22
GB2119804A (en) 1983-11-23
JPH0448440B2 (bg) 1992-08-06
BG60253B1 (bg) 1994-03-24
DD210303A5 (de) 1984-06-06
EP0093619B1 (en) 1989-09-13
AU563031B2 (en) 1987-06-25
CA1293211C (en) 1991-12-17
NO852065L (no) 1983-11-07
RO90639B (ro) 1987-01-31
JPH05137583A (ja) 1993-06-01
DE3316297A1 (de) 1983-11-17
IL68561A0 (en) 1983-09-30
FR2526443B1 (fr) 1985-12-06
GB2119804B (en) 1986-02-26
AU1414283A (en) 1983-11-10
DE3380567D1 (en) 1989-10-19
CS248705B2 (en) 1987-02-12
IE831024L (en) 1983-11-05
JPH0216981A (ja) 1990-01-19
ES522085A0 (es) 1984-12-16
CY1341A (en) 1987-01-16
DK174236B1 (da) 2002-10-07
RO90639A (ro) 1987-01-30
EP0093619A1 (en) 1983-11-09

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