NO981781L - Ekstrakter av haibrusk - Google Patents
Ekstrakter av haibruskInfo
- Publication number
- NO981781L NO981781L NO981781A NO981781A NO981781L NO 981781 L NO981781 L NO 981781L NO 981781 A NO981781 A NO 981781A NO 981781 A NO981781 A NO 981781A NO 981781 L NO981781 L NO 981781L
- Authority
- NO
- Norway
- Prior art keywords
- extracts
- extract
- liquid extract
- cartilage
- cartilage extracts
- Prior art date
Links
- 239000000284 extract Substances 0.000 title abstract 12
- 210000000845 cartilage Anatomy 0.000 title abstract 6
- 241000251730 Chondrichthyes Species 0.000 title abstract 3
- 239000007788 liquid Substances 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 5
- 239000007787 solid Substances 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 1
- 230000000791 anti-collagenolytic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000002537 cosmetic Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000989 no adverse effect Toxicity 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 230000008591 skin barrier function Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Marine Sciences & Fisheries (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Birds (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Plant Substances (AREA)
- Electrically Operated Instructional Devices (AREA)
- Medicinal Preparation (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
Den foreliggende oppfinnelse vedrører. bruskekstrakter og en fremgangsmåte for. fremstilling av samme. Haibruskekstrakter som har. antiangiogene, antitumorale, antiinflammatoriske. og antikollagenolytiske aktiviteter er blitt oppnådd. ved en forbedret fremgangsmåte. Fremgangsmåten. omfatter trinn for fremstilling av et homogenat av. brusk i en vanndig løsning, dette homogenat blir. separert i en fast fraksjon (fast ekstrakt) og en. flytende fraksjon som ble ytterligere fraksjonert for. å oppnå FLYTENDE EKSTRAKT som har. molekyler med en molekylvekt i området mellom 0. og 500 kDa. Blandingen av det flytende ekstrakt er. deretter blitt undersøkt på forskjellige måter.Ytterligere fraksjonering av dette ekstrakt førte til. den preliminære karakterisering av noen av dets. aktive komponenter. På grunn av de mange. biologiske aktiviteter av det totale flytende ekstrakt, kan det anvendes for behandling av mange forskjellige sykdommer eller tilstander såsom de som har komponenter valgt fra gruppen bestående av tumorproliferasjon, angiogenese, betennelse og kollagenolyse. Flere kosmetiske applikasjoner basert på evnen til det flytende ekstrakt til å forbedre hudbarrierefunksjonen er også innenfor rammen av denne oppfinnelse. Disse ekstrakter har ingen utiltalende virkning på normale kroppsfunksjoner. Disse haibruskekstrakter har derfor en svært lovende terapeutisk verdi. Fremgangsmåten for fremstillingen av bruskekstrakter er enkel og effektiv. De uventet verdifulle produkter som oppnås ved denne fremgangsmåte, er derfor en indikasjon på en ny og ikke åpenbar fremgangsmåte.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/550,003 US6025334A (en) | 1994-04-28 | 1995-10-30 | Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof |
| PCT/CA1996/000549 WO1997016197A1 (en) | 1995-10-30 | 1996-08-07 | Extracts of shark cartilage |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO981781D0 NO981781D0 (no) | 1998-04-21 |
| NO981781L true NO981781L (no) | 1998-06-19 |
Family
ID=24195326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO981781A NO981781L (no) | 1995-10-30 | 1998-04-21 | Ekstrakter av haibrusk |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6025334A (no) |
| EP (1) | EP0859622B1 (no) |
| JP (2) | JPH11513990A (no) |
| KR (1) | KR100296016B1 (no) |
| CN (1) | CN1187060C (no) |
| AT (1) | ATE230604T1 (no) |
| BG (1) | BG63907B1 (no) |
| BR (1) | BR9611507A (no) |
| CA (1) | CA2236021C (no) |
| CO (1) | CO4750839A1 (no) |
| CZ (1) | CZ129398A3 (no) |
| DE (1) | DE69625698T2 (no) |
| DK (1) | DK0859622T3 (no) |
| ES (1) | ES2190475T3 (no) |
| HK (1) | HK1015683A1 (no) |
| HU (1) | HU225490B1 (no) |
| IL (1) | IL119030A (no) |
| IN (1) | IN188198B (no) |
| IS (1) | IS2017B (no) |
| MX (1) | MX9803419A (no) |
| NO (1) | NO981781L (no) |
| NZ (1) | NZ313957A (no) |
| PL (1) | PL187989B1 (no) |
| RO (1) | RO118567B1 (no) |
| RU (1) | RU2181292C2 (no) |
| TW (1) | TW503108B (no) |
| WO (1) | WO1997016197A1 (no) |
| ZA (1) | ZA966726B (no) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6380366B1 (en) * | 1994-04-28 | 2002-04-30 | Les Laboratoires Aeterna Inc. | Shark cartilage extract:process of making, methods of using and compositions thereof |
| GB9621630D0 (en) * | 1996-10-17 | 1996-12-11 | Kappa Pharmaceuticals Ltd | Treatment of skin disorders |
| EP0842670A1 (en) * | 1996-11-13 | 1998-05-20 | Katsunari Nishihara | Biomedical materials |
| AU6639898A (en) | 1997-02-20 | 1998-09-09 | Industrial Research Limited | Angiogenesis inhibitors and activators from shark cartilage |
| DE69815310T2 (de) * | 1997-03-11 | 2004-04-22 | Les Laboratoires Aeterna Inc. | Zubereitungen zur tumorbehandlung enthaltend hai-knorpelextrakte und antineoplastische mittel |
| KR100732322B1 (ko) * | 1997-07-11 | 2007-06-25 | 에프엑스 라이프 싸이언스즈 인터내셔널 게엠베하 | 피에이취에프 과다 또는 세포내 칼슘 과다와 관련한질병을 치료하기 위한 상어 연골에서 유래한 조제물 |
| JPH11171782A (ja) * | 1997-12-03 | 1999-06-29 | Kaoru Yamane | 液体鮫軟骨の製造方法 |
| FR2778558B1 (fr) * | 1998-05-12 | 2001-02-16 | Oreal | Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute |
| US20020009501A1 (en) * | 1998-07-23 | 2002-01-24 | Eric Dupont | Preparation of cartilage extracts using organic solvents |
| US6168807B1 (en) | 1998-07-23 | 2001-01-02 | Les Laboratoires Aeterna Inc. | Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof |
| AU5687199A (en) * | 1998-08-24 | 2000-03-14 | Global Vascular Concepts, Inc. | Use of anti-angiogenic agents for inhibiting vessel wall injury |
| KR100355952B1 (ko) * | 2000-03-15 | 2002-10-11 | 주식회사 코리아나화장품 | 상어 연골추출물과 비타민 케이 유도체를 함유하는 화장료조성물 |
| WO2001074320A2 (de) * | 2000-03-31 | 2001-10-11 | Henkel Kommanditgesellschaft Auf Aktien | Verwendung von protease-inhibitoren in der kosmetik und pharmazie |
| JP2004516272A (ja) * | 2000-12-20 | 2004-06-03 | インダストリアル リサーチ リミテッド | サメ肉抽出物 |
| TWI233361B (en) * | 2001-04-13 | 2005-06-01 | Gen Hospital Corp | Methods of preventing UVB-induced skin damage |
| AU2002325108A1 (en) * | 2001-08-27 | 2003-03-10 | Les Laboratoires Aeterna Inc. | Serine protease inhibitor and processes for the preparation thereof |
| WO2003068249A1 (en) * | 2002-02-15 | 2003-08-21 | Ocean Nutrition Canada Limited | Shark cartilage extracts and use thereof for immunomodulation |
| US20080063677A1 (en) * | 2004-03-10 | 2008-03-13 | New Life Resources, Llc | Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations |
| WO2004083257A1 (ja) * | 2003-03-20 | 2004-09-30 | Hosokawa Micron Corporation | 軟骨魚類から単離されたプロテオグリカンおよびその製造方法 |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US20050222687A1 (en) * | 2004-04-02 | 2005-10-06 | Gordana Vunjak-Novakovic | Cartilage implant assembly and method for implantation |
| US20090291112A1 (en) * | 2003-05-16 | 2009-11-26 | Truncale Katherine G | Allograft osteochondral plug combined with cartilage particle mixture |
| US7901457B2 (en) * | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| ES2223291B1 (es) * | 2003-08-06 | 2006-03-16 | Bioiberica, S.A. | Nuevo uso terapeutico de condroitin sulfato. |
| EP2338442B1 (en) | 2003-12-11 | 2013-01-30 | Isto Technologies Inc. | Particulate cartilage system |
| KR100778992B1 (ko) * | 2004-01-07 | 2007-11-28 | 이엘씨 매니지먼트 엘엘씨 | 체모 성장을 지연시키기 위한 미용 조성물 및 방법 |
| US8580315B2 (en) * | 2004-03-10 | 2013-11-12 | Esm Technologies, Llc | Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations |
| US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
| US20080220044A1 (en) * | 2007-03-06 | 2008-09-11 | Semler Eric J | Cancellous construct with support ring for repair of osteochondral defects |
| US7837740B2 (en) * | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| WO2006059236A2 (en) * | 2004-11-16 | 2006-06-08 | Aeterna Zentaris Inc. | Method of using cartilage extract for increasing blood parameters |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| JP4875865B2 (ja) * | 2005-08-17 | 2012-02-15 | 株式会社日本バリアフリー | 変形性関節症の予防及び治療用ＮＴｘ値低減剤 |
| WO2007025290A2 (en) | 2005-08-26 | 2007-03-01 | Isto Technologies, Inc. | Implants and methods for repair, replacement and treatment of joint disease |
| JP2009508596A (ja) | 2005-09-19 | 2009-03-05 | ヒストジェニックス コーポレイション | 細胞支持基材及びその調製方法 |
| JP4834671B2 (ja) | 2005-09-29 | 2011-12-14 | 株式会社マルハニチロ水産 | 成人病の予防及び治療に有効な組成物 |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| US20080154233A1 (en) * | 2006-12-20 | 2008-06-26 | Zimmer Orthobiologics, Inc. | Apparatus for delivering a biocompatible material to a surgical site and method of using same |
| US8435551B2 (en) * | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| WO2008128075A1 (en) * | 2007-04-12 | 2008-10-23 | Isto Technologies, Inc. | Compositions and methods for tissue repair |
| WO2009076164A2 (en) * | 2007-12-05 | 2009-06-18 | Musculoskeletal Transplant Foundation | Cancellous bone implant for cartilage repair |
| WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| CA2749750C (en) * | 2008-04-15 | 2014-01-28 | Immanence Integrale Dermo Correction Inc. | Skin care compositions and methods of use thereof |
| CN103429608B (zh) * | 2011-01-19 | 2016-08-03 | 国立大学法人弘前大学 | 蛋白多糖的大量制备方法 |
| ES2403804B1 (es) * | 2011-09-21 | 2014-07-15 | Bioib�Rica, S.A. | Producto de cartílago. |
| ES2604559T3 (es) * | 2011-04-19 | 2017-03-07 | Bioiberica, S.A. | Producto de cartílago |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| RU2526825C1 (ru) * | 2013-06-18 | 2014-08-27 | Вера Геннадьевна Лихванцева | Фармацевтическая антиангиогенная композиция для лечения заболеваний глаз |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| CN104877009B (zh) * | 2015-05-11 | 2020-08-11 | 浙江海洋学院 | 一种赤魟软骨多肽类血管生成抑制因子 |
| EP3479834B1 (en) | 2016-07-04 | 2022-09-07 | Kangstem Biotech Co., Ltd. | Complex comprising cartilage cell-free lysate and stem cell for promoting cartilage differentiation and use thereof |
| KR102154976B1 (ko) * | 2018-08-30 | 2020-09-11 | 전남대학교산학협력단 | 구내염 치료용 하이드로겔 |
| KR102369902B1 (ko) * | 2021-04-23 | 2022-03-02 | 이수한 | 전 처리된 캐비아가 함유된 철갑상어 진액 및 그 제조 방법 |
| KR20220166032A (ko) | 2021-06-09 | 2022-12-16 | 아스코코리아 주식회사 | 조립식 캠핑 테이블 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3478146A (en) * | 1965-02-26 | 1969-11-11 | Leslie L Balassa | Wound-healing cartilage powder extracting process |
| US4042457A (en) * | 1975-11-10 | 1977-08-16 | Rush-Presbyterian-St. Luke's Medical Center | Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor |
| US4822607A (en) * | 1976-10-29 | 1989-04-18 | Lescarden Ltd. | Anti-tumor agent and method |
| US4243582A (en) * | 1979-04-26 | 1981-01-06 | Monsanto Company | Novel glycoproteins from bovine cartilage |
| US4350682A (en) * | 1979-05-11 | 1982-09-21 | Lescarden Ltd. | Cartilage extraction processes and products |
| US4356261A (en) * | 1980-04-22 | 1982-10-26 | Rush-Presbyterian-St. Luke's Medical Center | Anti-invasion factor containing cultures |
| US4473551A (en) * | 1982-08-23 | 1984-09-25 | Faxon Pharmaceuticals, Inc. | Anti-inflammatory composition |
| US4656137A (en) * | 1985-09-12 | 1987-04-07 | Lescarden Inc | Method of processing animal cartilage |
| US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
| US4746729A (en) * | 1986-07-30 | 1988-05-24 | Kuettner Klaus E | Cartilage-derived leukocyte elastase-inhibitor |
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| JPH0870822A (ja) * | 1994-09-01 | 1996-03-19 | Makoma Kk | カプセル入り食品及びその製造法 |
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1995
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1996
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