MX9803419A - Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos. - Google Patents
Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos.Info
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- MX9803419A MX9803419A MX9803419A MX9803419A MX9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Marine Sciences & Fisheries (AREA)
- Birds (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Electrically Operated Instructional Devices (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
La presente invencion se relaciona con extractos de cartílago y con un método para producir los mismos. Los extractos de cartílago de tiburon tienen actividades antigiogénica, anti-tumoral, anti-inflamatoria y anti-colagenolítica y se han obtenido por un proceso mejorado. El proceso comprende el paso de obtener un homogenado de cartílago en una solucion acuosa, este homogenado se separa en una fraccion solida (EXTRACTO SOLIDO) y en una fraccion líquida que se fracciona adicionalmente para obtener un EXTRACTO LIQUIDO, que tiene moléculas de un peso molecular comprendido entre 0 y 500 kDa. La composicion del extracto líquido se ha investigado por diferentes formas. La fraccionacion adicional de este extracto condujo a la caracterizacion preliminar de algunos de sus componentes activos. Devido a la multiplicidad de actividades biologicas del extracto líquido total, este puede usarse para tratar varias enfermedades o condiciones como aquellas que tienen componentes seleccionados del grupo que consiste de: proliferacion de tumor, angiogénesis, inflamacion y colagenolisis. Varias aplicaciones cosméticas que se basan en la capacidad del extremo líquido para mejorar las funciones de barrera de la piel también quedan dentro del alcance de esta invencion. Estos extractos no tienen efecto ofensivo sobre las funciones normales del cuerpo. Por lo tanto, estos extractos de cartílago de tiburon tiene un valor terapéutico muy prometedor. El proceso para la obtencion de los extractos de cartílago es simple y eficiente. Los productos inesperadamente valiosos que se obtienen por este proceso son, por lo tanto, una indicacion de un proceso nuevo y no obvio.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/550,003 US6025334A (en) | 1994-04-28 | 1995-10-30 | Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9803419A true MX9803419A (es) | 1998-10-31 |
Family
ID=24195326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9803419A MX9803419A (es) | 1995-10-30 | 1998-04-30 | Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos. |
Country Status (28)
Country | Link |
---|---|
US (1) | US6025334A (es) |
EP (1) | EP0859622B1 (es) |
JP (2) | JPH11513990A (es) |
KR (1) | KR100296016B1 (es) |
CN (1) | CN1187060C (es) |
AT (1) | ATE230604T1 (es) |
BG (1) | BG63907B1 (es) |
BR (1) | BR9611507A (es) |
CA (1) | CA2236021C (es) |
CO (1) | CO4750839A1 (es) |
CZ (1) | CZ129398A3 (es) |
DE (1) | DE69625698T2 (es) |
DK (1) | DK0859622T3 (es) |
ES (1) | ES2190475T3 (es) |
HK (1) | HK1015683A1 (es) |
HU (1) | HU225490B1 (es) |
IL (1) | IL119030A (es) |
IN (1) | IN188198B (es) |
IS (1) | IS2017B (es) |
MX (1) | MX9803419A (es) |
NO (1) | NO981781L (es) |
NZ (1) | NZ313957A (es) |
PL (1) | PL187989B1 (es) |
RO (1) | RO118567B1 (es) |
RU (1) | RU2181292C2 (es) |
TW (1) | TW503108B (es) |
WO (1) | WO1997016197A1 (es) |
ZA (1) | ZA966726B (es) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6380366B1 (en) * | 1994-04-28 | 2002-04-30 | Les Laboratoires Aeterna Inc. | Shark cartilage extract:process of making, methods of using and compositions thereof |
GB9621630D0 (en) * | 1996-10-17 | 1996-12-11 | Kappa Pharmaceuticals Ltd | Treatment of skin disorders |
EP0842670A1 (en) * | 1996-11-13 | 1998-05-20 | Katsunari Nishihara | Biomedical materials |
CA2288269A1 (en) | 1997-02-20 | 1998-08-27 | Industrial Research Limited | Angiogenesis inhibitors and activators from shark cartilage |
WO1998040088A1 (en) | 1997-03-11 | 1998-09-17 | Les Laboratoires Aeterna Inc. | Compositions for treating tumors containing shark cartilage extracts and anti-neoplastic agents |
CN1288165C (zh) * | 1997-07-11 | 2006-12-06 | Cv技术公司 | 用于治疗与phf过多或细胞内钙过多相关疾病的来自鲨软骨的制剂 |
JPH11171782A (ja) * | 1997-12-03 | 1999-06-29 | Kaoru Yamane | 液体鮫軟骨の製造方法 |
FR2778558B1 (fr) * | 1998-05-12 | 2001-02-16 | Oreal | Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute |
US6168807B1 (en) * | 1998-07-23 | 2001-01-02 | Les Laboratoires Aeterna Inc. | Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof |
US20020009501A1 (en) * | 1998-07-23 | 2002-01-24 | Eric Dupont | Preparation of cartilage extracts using organic solvents |
WO2000010552A2 (en) * | 1998-08-24 | 2000-03-02 | Global Vascular Concepts, Inc. | Use of anti-angiogenic agents for inhibiting vessel wall injury |
KR100355952B1 (ko) * | 2000-03-15 | 2002-10-11 | 주식회사 코리아나화장품 | 상어 연골추출물과 비타민 케이 유도체를 함유하는 화장료조성물 |
AU2001242502A1 (en) * | 2000-03-31 | 2001-10-15 | Henkel Kommanditgesellschaft Auf Aktien | Use of protease inhibitors in cosmetics and pharmacy |
CN1245991C (zh) * | 2000-12-20 | 2006-03-22 | 工业研究有限公司 | 鲨鱼肉提取物 |
TWI233361B (en) * | 2001-04-13 | 2005-06-01 | Gen Hospital Corp | Methods of preventing UVB-induced skin damage |
WO2003018620A2 (en) * | 2001-08-27 | 2003-03-06 | Les Laboratoires Aeterna Inc. | Serine protease inhibitor and processes for the preparation thereof |
US7504115B2 (en) | 2002-02-15 | 2009-03-17 | Ocean Nutrition Canada Limited | Shark cartilage extracts and use thereof for immunomodulation |
US20080063677A1 (en) * | 2004-03-10 | 2008-03-13 | New Life Resources, Llc | Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations |
JPWO2004083257A1 (ja) * | 2003-03-20 | 2006-06-22 | ホソカワミクロン株式会社 | 軟骨魚類から単離されたプロテオグリカンおよびその製造方法 |
US20050222687A1 (en) * | 2004-04-02 | 2005-10-06 | Gordana Vunjak-Novakovic | Cartilage implant assembly and method for implantation |
US7067123B2 (en) * | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US20090291112A1 (en) * | 2003-05-16 | 2009-11-26 | Truncale Katherine G | Allograft osteochondral plug combined with cartilage particle mixture |
US7901457B2 (en) * | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
ES2223291B1 (es) * | 2003-08-06 | 2006-03-16 | Bioiberica, S.A. | Nuevo uso terapeutico de condroitin sulfato. |
EP2338441B1 (en) | 2003-12-11 | 2013-01-23 | Isto Technologies Inc. | Particulate cartilage system |
JP4390809B2 (ja) * | 2004-01-07 | 2009-12-24 | イーエルシー マネージメント エルエルシー | 発毛遅延のための化粧品組成物及び方法 |
US8580315B2 (en) * | 2004-03-10 | 2013-11-12 | Esm Technologies, Llc | Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations |
US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
US7837740B2 (en) * | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US20080220044A1 (en) * | 2007-03-06 | 2008-09-11 | Semler Eric J | Cancellous construct with support ring for repair of osteochondral defects |
WO2006059236A2 (en) * | 2004-11-16 | 2006-06-08 | Aeterna Zentaris Inc. | Method of using cartilage extract for increasing blood parameters |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
JP4875865B2 (ja) * | 2005-08-17 | 2012-02-15 | 株式会社日本バリアフリー | 変形性関節症の予防及び治療用NTx値低減剤 |
WO2007025290A2 (en) | 2005-08-26 | 2007-03-01 | Isto Technologies, Inc. | Implants and methods for repair, replacement and treatment of joint disease |
CA2623106C (en) | 2005-09-19 | 2013-12-24 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
JP4834671B2 (ja) | 2005-09-29 | 2011-12-14 | 株式会社マルハニチロ水産 | 成人病の予防及び治療に有効な組成物 |
US20080154233A1 (en) * | 2006-12-20 | 2008-06-26 | Zimmer Orthobiologics, Inc. | Apparatus for delivering a biocompatible material to a surgical site and method of using same |
US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
US8435551B2 (en) * | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
AU2008240191B2 (en) | 2007-04-12 | 2013-09-19 | Zimmer, Inc. | Compositions and methods for tissue repair |
CA2708147A1 (en) * | 2007-12-05 | 2009-06-18 | Musculoskeletal Transplant Foundation | Cancellous bone implant for cartilage repair |
EP2265220A1 (en) | 2008-03-05 | 2010-12-29 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
EP2262469A4 (en) * | 2008-04-15 | 2013-12-04 | Immanence Integrale Dermo Correction Inc | SKIN CARE COMPOSITIONS AND METHODS OF USE |
CN103429608B (zh) * | 2011-01-19 | 2016-08-03 | 国立大学法人弘前大学 | 蛋白多糖的大量制备方法 |
ES2403804B1 (es) * | 2011-09-21 | 2014-07-15 | Bioib�Rica, S.A. | Producto de cartílago. |
US9347081B2 (en) | 2011-04-19 | 2016-05-24 | Bioiberica, S.A. | Cartilage product |
US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
RU2526825C1 (ru) * | 2013-06-18 | 2014-08-27 | Вера Геннадьевна Лихванцева | Фармацевтическая антиангиогенная композиция для лечения заболеваний глаз |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
CN104877009B (zh) * | 2015-05-11 | 2020-08-11 | 浙江海洋学院 | 一种赤魟软骨多肽类血管生成抑制因子 |
KR101901568B1 (ko) | 2016-07-04 | 2018-09-28 | 주식회사 강스템바이오텍 | 연골 무세포 파쇄물 및 줄기세포를 포함하는 연골분화 촉진용 복합체 및 그의 용도 |
KR102154976B1 (ko) * | 2018-08-30 | 2020-09-11 | 전남대학교산학협력단 | 구내염 치료용 하이드로겔 |
KR102369902B1 (ko) * | 2021-04-23 | 2022-03-02 | 이수한 | 전 처리된 캐비아가 함유된 철갑상어 진액 및 그 제조 방법 |
KR20220166032A (ko) | 2021-06-09 | 2022-12-16 | 아스코코리아 주식회사 | 조립식 캠핑 테이블 |
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US3478146A (en) * | 1965-02-26 | 1969-11-11 | Leslie L Balassa | Wound-healing cartilage powder extracting process |
US4042457A (en) * | 1975-11-10 | 1977-08-16 | Rush-Presbyterian-St. Luke's Medical Center | Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor |
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US4356261A (en) * | 1980-04-22 | 1982-10-26 | Rush-Presbyterian-St. Luke's Medical Center | Anti-invasion factor containing cultures |
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US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
US4746729A (en) * | 1986-07-30 | 1988-05-24 | Kuettner Klaus E | Cartilage-derived leukocyte elastase-inhibitor |
US5075112A (en) * | 1990-02-12 | 1991-12-24 | Cartilage Technologies Inc. | Method of and dosage unit for inhibiting angiogenesis or vascularization in an animal using shark cartilage |
AU5596494A (en) * | 1992-11-30 | 1994-06-22 | I. William Lane | Processing shark cartilage |
NZ533467A (en) * | 1993-07-19 | 2006-02-24 | Angiotech Pharm Inc | Anti-angiogenic compositions and methods of use |
US5618925A (en) * | 1994-04-28 | 1997-04-08 | Les Laboratories Aeterna Inc. | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
JPH0870822A (ja) * | 1994-09-01 | 1996-03-19 | Makoma Kk | カプセル入り食品及びその製造法 |
CZ292627B6 (cs) * | 1995-02-03 | 2003-11-12 | Les Laboratoires Aeterna Inc. | Léčivo pro léčení nemocí nebo poruch majících složku kolagenolytickou nebo zánětlivou |
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1995
- 1995-10-30 US US08/550,003 patent/US6025334A/en not_active Expired - Fee Related
-
1996
- 1996-08-07 PL PL32688896A patent/PL187989B1/pl not_active IP Right Cessation
- 1996-08-07 RO RO98-00923A patent/RO118567B1/ro unknown
- 1996-08-07 WO PCT/CA1996/000549 patent/WO1997016197A1/en not_active Application Discontinuation
- 1996-08-07 DE DE69625698T patent/DE69625698T2/de not_active Expired - Lifetime
- 1996-08-07 DK DK96926300T patent/DK0859622T3/da active
- 1996-08-07 CA CA002236021A patent/CA2236021C/en not_active Expired - Lifetime
- 1996-08-07 BR BR9611507-6A patent/BR9611507A/pt not_active Application Discontinuation
- 1996-08-07 KR KR1019980703204A patent/KR100296016B1/ko not_active IP Right Cessation
- 1996-08-07 AT AT96926300T patent/ATE230604T1/de not_active IP Right Cessation
- 1996-08-07 ZA ZA9606726A patent/ZA966726B/xx unknown
- 1996-08-07 RU RU98110005/14A patent/RU2181292C2/ru active
- 1996-08-07 HU HU9802604A patent/HU225490B1/hu not_active IP Right Cessation
- 1996-08-07 NZ NZ313957A patent/NZ313957A/xx not_active IP Right Cessation
- 1996-08-07 CN CNB961987634A patent/CN1187060C/zh not_active Expired - Lifetime
- 1996-08-07 JP JP9516934A patent/JPH11513990A/ja active Pending
- 1996-08-07 IL IL11903096A patent/IL119030A/xx not_active IP Right Cessation
- 1996-08-07 ES ES96926300T patent/ES2190475T3/es not_active Expired - Lifetime
- 1996-08-07 CZ CZ981293A patent/CZ129398A3/cs unknown
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- 1996-10-01 TW TW085109647A patent/TW503108B/zh not_active IP Right Cessation
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1998
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1999
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2003
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