MX9803419A - Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos. - Google Patents
Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos.Info
- Publication number
- MX9803419A MX9803419A MX9803419A MX9803419A MX9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A MX 9803419 A MX9803419 A MX 9803419A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/60—Fish, e.g. seahorses; Fish eggs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Marine Sciences & Fisheries (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Birds (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Meat, Egg Or Seafood Products (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Electrically Operated Instructional Devices (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
La presente invencion se relaciona con extractos de cartílago y con un método para producir los mismos. Los extractos de cartílago de tiburon tienen actividades antigiogénica, anti-tumoral, anti-inflamatoria y anti-colagenolítica y se han obtenido por un proceso mejorado. El proceso comprende el paso de obtener un homogenado de cartílago en una solucion acuosa, este homogenado se separa en una fraccion solida (EXTRACTO SOLIDO) y en una fraccion líquida que se fracciona adicionalmente para obtener un EXTRACTO LIQUIDO, que tiene moléculas de un peso molecular comprendido entre 0 y 500 kDa. La composicion del extracto líquido se ha investigado por diferentes formas. La fraccionacion adicional de este extracto condujo a la caracterizacion preliminar de algunos de sus componentes activos. Devido a la multiplicidad de actividades biologicas del extracto líquido total, este puede usarse para tratar varias enfermedades o condiciones como aquellas que tienen componentes seleccionados del grupo que consiste de: proliferacion de tumor, angiogénesis, inflamacion y colagenolisis. Varias aplicaciones cosméticas que se basan en la capacidad del extremo líquido para mejorar las funciones de barrera de la piel también quedan dentro del alcance de esta invencion. Estos extractos no tienen efecto ofensivo sobre las funciones normales del cuerpo. Por lo tanto, estos extractos de cartílago de tiburon tiene un valor terapéutico muy prometedor. El proceso para la obtencion de los extractos de cartílago es simple y eficiente. Los productos inesperadamente valiosos que se obtienen por este proceso son, por lo tanto, una indicacion de un proceso nuevo y no obvio.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/550,003 US6025334A (en) | 1994-04-28 | 1995-10-30 | Extracts of shark cartilage having anti-collagenolytic, anti-inflammatory, anti-angiogenic and anti-tumoral activities; process of making, methods of using and compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9803419A true MX9803419A (es) | 1998-10-31 |
Family
ID=24195326
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9803419A MX9803419A (es) | 1995-10-30 | 1998-04-30 | Extractos de cartilago de tiburon que tienen actividades anti-colagenolitica, anti-inflamatoria, anti-angiogenica y anti-tumoral, procesos para elaborarlos, metodos de utilizacion y composiciones de los mismos. |
Country Status (28)
Country | Link |
---|---|
US (1) | US6025334A (es) |
EP (1) | EP0859622B1 (es) |
JP (2) | JPH11513990A (es) |
KR (1) | KR100296016B1 (es) |
CN (1) | CN1187060C (es) |
AT (1) | ATE230604T1 (es) |
BG (1) | BG63907B1 (es) |
BR (1) | BR9611507A (es) |
CA (1) | CA2236021C (es) |
CO (1) | CO4750839A1 (es) |
CZ (1) | CZ129398A3 (es) |
DE (1) | DE69625698T2 (es) |
DK (1) | DK0859622T3 (es) |
ES (1) | ES2190475T3 (es) |
HK (1) | HK1015683A1 (es) |
HU (1) | HU225490B1 (es) |
IL (1) | IL119030A (es) |
IN (1) | IN188198B (es) |
IS (1) | IS2017B (es) |
MX (1) | MX9803419A (es) |
NO (1) | NO981781L (es) |
NZ (1) | NZ313957A (es) |
PL (1) | PL187989B1 (es) |
RO (1) | RO118567B1 (es) |
RU (1) | RU2181292C2 (es) |
TW (1) | TW503108B (es) |
WO (1) | WO1997016197A1 (es) |
ZA (1) | ZA966726B (es) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6380366B1 (en) * | 1994-04-28 | 2002-04-30 | Les Laboratoires Aeterna Inc. | Shark cartilage extract:process of making, methods of using and compositions thereof |
GB9621630D0 (en) * | 1996-10-17 | 1996-12-11 | Kappa Pharmaceuticals Ltd | Treatment of skin disorders |
EP0842670A1 (en) * | 1996-11-13 | 1998-05-20 | Katsunari Nishihara | Biomedical materials |
CA2288269A1 (en) | 1997-02-20 | 1998-08-27 | Industrial Research Limited | Angiogenesis inhibitors and activators from shark cartilage |
IL131701A (en) * | 1997-03-11 | 2005-03-20 | Aeterna Zentaris Inc | Compositions for treating tumors containing shark cartilage extracts and anti-neoplastic agents |
AU8379098A (en) * | 1997-07-11 | 1999-02-08 | Cv Technologies Inc. | A preparation derived from shark cartilage for treatment of diseases related to excessive phf or excessive intracellular calcium |
JPH11171782A (ja) * | 1997-12-03 | 1999-06-29 | Kaoru Yamane | 液体鮫軟骨の製造方法 |
FR2778558B1 (fr) | 1998-05-12 | 2001-02-16 | Oreal | Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute |
US20020009501A1 (en) * | 1998-07-23 | 2002-01-24 | Eric Dupont | Preparation of cartilage extracts using organic solvents |
US6168807B1 (en) | 1998-07-23 | 2001-01-02 | Les Laboratoires Aeterna Inc. | Low molecular weight components of shark cartilage, processes for their preparation and therapeutic uses thereof |
AU5687199A (en) * | 1998-08-24 | 2000-03-14 | Global Vascular Concepts, Inc. | Use of anti-angiogenic agents for inhibiting vessel wall injury |
KR100355952B1 (ko) * | 2000-03-15 | 2002-10-11 | 주식회사 코리아나화장품 | 상어 연골추출물과 비타민 케이 유도체를 함유하는 화장료조성물 |
AU2001242502A1 (en) * | 2000-03-31 | 2001-10-15 | Henkel Kommanditgesellschaft Auf Aktien | Use of protease inhibitors in cosmetics and pharmacy |
BR0114470A (pt) * | 2000-12-20 | 2004-01-13 | Ind Res Ltd | Extrato de carne de tubarão |
TWI233361B (en) * | 2001-04-13 | 2005-06-01 | Gen Hospital Corp | Methods of preventing UVB-induced skin damage |
AU2002325108A1 (en) * | 2001-08-27 | 2003-03-10 | Les Laboratoires Aeterna Inc. | Serine protease inhibitor and processes for the preparation thereof |
CA2476126A1 (en) * | 2002-02-15 | 2003-08-21 | Ocean Nutrition Canada Limited | Shark cartilage extracts and use thereof for immunomodulation |
US20080063677A1 (en) * | 2004-03-10 | 2008-03-13 | New Life Resources, Llc | Therapeutic, nutraceutical and cosmetic applications for eggshell membrane and processed eggshell membrane preparations |
US20070010430A1 (en) * | 2003-03-20 | 2007-01-11 | Hosokawa Micron Corparation | Proteoglycan isolated from cartilaginous fish and process for producing the same |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US20050222687A1 (en) * | 2004-04-02 | 2005-10-06 | Gordana Vunjak-Novakovic | Cartilage implant assembly and method for implantation |
US20090291112A1 (en) * | 2003-05-16 | 2009-11-26 | Truncale Katherine G | Allograft osteochondral plug combined with cartilage particle mixture |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
ES2223291B1 (es) * | 2003-08-06 | 2006-03-16 | Bioiberica, S.A. | Nuevo uso terapeutico de condroitin sulfato. |
EP2335650B1 (en) | 2003-12-11 | 2012-10-03 | Isto Technologies Inc. | Particulate cartilage system |
JP4390809B2 (ja) * | 2004-01-07 | 2009-12-24 | イーエルシー マネージメント エルエルシー | 発毛遅延のための化粧品組成物及び方法 |
US8580315B2 (en) * | 2004-03-10 | 2013-11-12 | Esm Technologies, Llc | Anti-inflammatory activity of eggshell membrane and processed eggshell membrane preparations |
US20050288796A1 (en) * | 2004-06-23 | 2005-12-29 | Hani Awad | Native soft tissue matrix for therapeutic applications |
US7837740B2 (en) * | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US20080220044A1 (en) * | 2007-03-06 | 2008-09-11 | Semler Eric J | Cancellous construct with support ring for repair of osteochondral defects |
WO2006059236A2 (en) * | 2004-11-16 | 2006-06-08 | Aeterna Zentaris Inc. | Method of using cartilage extract for increasing blood parameters |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
JP4875865B2 (ja) * | 2005-08-17 | 2012-02-15 | 株式会社日本バリアフリー | 変形性関節症の予防及び治療用NTx値低減剤 |
US8480757B2 (en) | 2005-08-26 | 2013-07-09 | Zimmer, Inc. | Implants and methods for repair, replacement and treatment of disease |
US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
US7951782B2 (en) | 2005-09-29 | 2011-05-31 | Maruha Nichiro Seafoods, Inc | Composition effective to prevent or treat adult disease |
US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
US20080154233A1 (en) * | 2006-12-20 | 2008-06-26 | Zimmer Orthobiologics, Inc. | Apparatus for delivering a biocompatible material to a surgical site and method of using same |
US8435551B2 (en) * | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
AU2008240191B2 (en) | 2007-04-12 | 2013-09-19 | Zimmer, Inc. | Compositions and methods for tissue repair |
EP2224884A2 (en) * | 2007-12-05 | 2010-09-08 | Musculoskeletal Transplant Foundation | Cancellous bone implant for cartilage repair |
CA2717725A1 (en) * | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
EP2262469A4 (en) * | 2008-04-15 | 2013-12-04 | Immanence Integrale Dermo Correction Inc | SKIN CARE COMPOSITIONS AND METHODS OF USE |
RU2592850C2 (ru) * | 2011-01-19 | 2016-07-27 | Хиросаки Юниверсити | Способ крупномасштабного получения протеогликана |
US9347081B2 (en) | 2011-04-19 | 2016-05-24 | Bioiberica, S.A. | Cartilage product |
ES2403804B1 (es) * | 2011-09-21 | 2014-07-15 | Bioib�Rica, S.A. | Producto de cartílago. |
US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
RU2526825C1 (ru) * | 2013-06-18 | 2014-08-27 | Вера Геннадьевна Лихванцева | Фармацевтическая антиангиогенная композиция для лечения заболеваний глаз |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
CN104877009B (zh) * | 2015-05-11 | 2020-08-11 | 浙江海洋学院 | 一种赤魟软骨多肽类血管生成抑制因子 |
JP6929346B2 (ja) | 2016-07-04 | 2021-09-01 | カンステム バイオテック カンパニー リミテッド | 軟骨無細胞破砕物及び幹細胞を含む軟骨分化促進用複合体及びその用途 |
KR102154976B1 (ko) * | 2018-08-30 | 2020-09-11 | 전남대학교산학협력단 | 구내염 치료용 하이드로겔 |
KR102369902B1 (ko) * | 2021-04-23 | 2022-03-02 | 이수한 | 전 처리된 캐비아가 함유된 철갑상어 진액 및 그 제조 방법 |
KR20220166032A (ko) | 2021-06-09 | 2022-12-16 | 아스코코리아 주식회사 | 조립식 캠핑 테이블 |
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US3478146A (en) * | 1965-02-26 | 1969-11-11 | Leslie L Balassa | Wound-healing cartilage powder extracting process |
US4042457A (en) * | 1975-11-10 | 1977-08-16 | Rush-Presbyterian-St. Luke's Medical Center | Preparation of tissue invasion inhibitor and method of treatment utilizing the inhibitor |
US4822607A (en) * | 1976-10-29 | 1989-04-18 | Lescarden Ltd. | Anti-tumor agent and method |
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US4356261A (en) * | 1980-04-22 | 1982-10-26 | Rush-Presbyterian-St. Luke's Medical Center | Anti-invasion factor containing cultures |
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US4656137A (en) * | 1985-09-12 | 1987-04-07 | Lescarden Inc | Method of processing animal cartilage |
US4749522A (en) * | 1985-10-31 | 1988-06-07 | Angio-Medical Corporation | Supercritical fluid extraction of animal derived materials |
US4746729A (en) * | 1986-07-30 | 1988-05-24 | Kuettner Klaus E | Cartilage-derived leukocyte elastase-inhibitor |
US5075112A (en) * | 1990-02-12 | 1991-12-24 | Cartilage Technologies Inc. | Method of and dosage unit for inhibiting angiogenesis or vascularization in an animal using shark cartilage |
WO1994012510A1 (en) * | 1992-11-30 | 1994-06-09 | Lane I William | Processing shark cartilage |
NZ511762A (en) * | 1993-07-19 | 2003-09-26 | Univ British Columbia | Anti-angiogenic compositions and methods of use |
US5618925A (en) * | 1994-04-28 | 1997-04-08 | Les Laboratories Aeterna Inc. | Extracts of shark cartilage having an anti-angiogenic activity and an effect on tumor regression; process of making thereof |
JPH0870822A (ja) * | 1994-09-01 | 1996-03-19 | Makoma Kk | カプセル入り食品及びその製造法 |
CZ292627B6 (cs) * | 1995-02-03 | 2003-11-12 | Les Laboratoires Aeterna Inc. | Léčivo pro léčení nemocí nebo poruch majících složku kolagenolytickou nebo zánětlivou |
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1995
- 1995-10-30 US US08/550,003 patent/US6025334A/en not_active Expired - Fee Related
-
1996
- 1996-08-07 CN CNB961987634A patent/CN1187060C/zh not_active Expired - Lifetime
- 1996-08-07 BR BR9611507-6A patent/BR9611507A/pt not_active Application Discontinuation
- 1996-08-07 DK DK96926300T patent/DK0859622T3/da active
- 1996-08-07 ZA ZA9606726A patent/ZA966726B/xx unknown
- 1996-08-07 JP JP9516934A patent/JPH11513990A/ja active Pending
- 1996-08-07 KR KR1019980703204A patent/KR100296016B1/ko not_active IP Right Cessation
- 1996-08-07 HU HU9802604A patent/HU225490B1/hu not_active IP Right Cessation
- 1996-08-07 IL IL11903096A patent/IL119030A/xx not_active IP Right Cessation
- 1996-08-07 PL PL32688896A patent/PL187989B1/pl not_active IP Right Cessation
- 1996-08-07 RU RU98110005/14A patent/RU2181292C2/ru active
- 1996-08-07 DE DE69625698T patent/DE69625698T2/de not_active Expired - Lifetime
- 1996-08-07 WO PCT/CA1996/000549 patent/WO1997016197A1/en not_active Application Discontinuation
- 1996-08-07 AT AT96926300T patent/ATE230604T1/de not_active IP Right Cessation
- 1996-08-07 RO RO98-00923A patent/RO118567B1/ro unknown
- 1996-08-07 ES ES96926300T patent/ES2190475T3/es not_active Expired - Lifetime
- 1996-08-07 EP EP96926300A patent/EP0859622B1/en not_active Expired - Lifetime
- 1996-08-07 CA CA002236021A patent/CA2236021C/en not_active Expired - Lifetime
- 1996-08-07 NZ NZ313957A patent/NZ313957A/xx not_active IP Right Cessation
- 1996-08-07 CZ CZ981293A patent/CZ129398A3/cs unknown
- 1996-08-08 CO CO96042024A patent/CO4750839A1/es unknown
- 1996-08-09 IN IN1427CA1996 patent/IN188198B/en unknown
- 1996-10-01 TW TW085109647A patent/TW503108B/zh not_active IP Right Cessation
-
1998
- 1998-04-21 NO NO981781A patent/NO981781L/no not_active Application Discontinuation
- 1998-04-29 IS IS4728A patent/IS2017B/is unknown
- 1998-04-29 BG BG102419A patent/BG63907B1/bg unknown
- 1998-04-30 MX MX9803419A patent/MX9803419A/es unknown
-
1999
- 1999-02-23 HK HK99100722A patent/HK1015683A1/xx not_active IP Right Cessation
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2003
- 2003-01-14 JP JP2003005998A patent/JP2003246740A/ja active Pending
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